BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0254.0001.p (202 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C2W3L2.1 C2W3L2_BACCE Transcriptional regulator, TetR 142 1e-32 A9VSK0.1 A9VSK0_BACWK Transcriptional regulator, TetR family 137 5e-31 C3A0T6.1 C3A0T6_BACMY Transcriptional regulator, TetR 137 5e-31 C2XNW2.1 C2XNW2_BACCE Transcriptional regulator, TetR 137 6e-31 C3BFI9.1 C3BFI9_9BACI Transcriptional regulator, TetR 137 6e-31 >C2W3L2.1 C2W3L2_BACCE Transcriptional regulator, TetR Length = 194 Score = 142 bits (359), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 71/195 (36%), Positives = 115/195 (58%), Gaps = 4/195 (2%) Query: 7 RSDGEETKKRIVQKAAQLFVQKGYGAVTMNEVCSAAKVSKGSLYHHFPSKDELFLYVVED 66 R EE KK I +A +LF QKGY A +M E+C K SKGS+Y+HF SK+ELFL+VV+ Sbjct: 2 RKSAEEIKKEIAYQAEELFSQKGYAATSMEEICEITKRSKGSIYYHFKSKEELFLFVVKQ 61 Query: 67 DTEQWLSQWAEKSRSISGLEERFYALGEHYANDFQNPLIRALEEYARARPHSDEVHQRLA 126 T WL +W E+ + E+ Y L E++ D Q P+ A+EE++ ++ E+ + Sbjct: 62 HTYDWLEKWNEREKQYHTSTEKLYGLAEYHVEDIQQPIFSAVEEFSMSQVVGKEILDEML 121 Query: 127 QLYESASEACRNLLQEGMDSGYLVKGDLDNYVIVVSGLLEGVARVSEIMAAAKAPEDIMQ 186 L ++ L++EG+ SG +GD+ + + +V+GLL G+ ++ P ++ + Sbjct: 122 VLARASYGVFEKLIEEGIKSGEFRQGDIRDLMYIVNGLLSGLG----VLYYELDPAEMKR 177 Query: 187 YYREAIGLLLQGIRA 201 Y++AI +LLQG+ A Sbjct: 178 IYKKAIDVLLQGLAA 192 >A9VSK0.1 A9VSK0_BACWK Transcriptional regulator, TetR family Length = 193 Score = 137 bits (345), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 72/195 (36%), Positives = 112/195 (57%), Gaps = 4/195 (2%) Query: 7 RSDGEETKKRIVQKAAQLFVQKGYGAVTMNEVCSAAKVSKGSLYHHFPSKDELFLYVVED 66 R EE KK I KA LF QKGY A +M E+C + SKGS+Y+HF SK+ELFL+VV+ Sbjct: 2 RRSAEEIKKEIAYKAESLFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQ 61 Query: 67 DTEQWLSQWAEKSRSISGLEERFYALGEHYANDFQNPLIRALEEYARARPHSDEVHQRLA 126 T WL +W EK + S E+ Y L E+Y D Q P+ A+EE++ ++ S E+ L Sbjct: 62 HTYDWLEKWNEKEKLYSTSTEKLYGLAEYYVEDIQQPISNAIEEFSMSQVVSKEILDELL 121 Query: 127 QLYESASEACRNLLQEGMDSGYLVKGDLDNYVIVVSGLLEGVARVSEIMAAAKAPEDIMQ 186 L + L++ G+ SG + D + + +V+GLL G+ ++ +++ + Sbjct: 122 ALTRESYVMVEKLIEAGIQSGEFQEDDTRDLMYIVNGLLSGLG----VLYYELDYKELKR 177 Query: 187 YYREAIGLLLQGIRA 201 Y++AI +LL+G+ A Sbjct: 178 IYKKAIDVLLKGMAA 192 >C3A0T6.1 C3A0T6_BACMY Transcriptional regulator, TetR Length = 193 Score = 137 bits (345), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 72/195 (36%), Positives = 112/195 (57%), Gaps = 4/195 (2%) Query: 7 RSDGEETKKRIVQKAAQLFVQKGYGAVTMNEVCSAAKVSKGSLYHHFPSKDELFLYVVED 66 R EE KK I KA LF QKGY A +M E+C + SKGS+Y+HF SK+ELFL+VV+ Sbjct: 2 RRSAEEIKKEIAYKAESLFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQ 61 Query: 67 DTEQWLSQWAEKSRSISGLEERFYALGEHYANDFQNPLIRALEEYARARPHSDEVHQRLA 126 T WL +W EK + S E+ Y L E+Y D Q P+ A+EE++ ++ S E+ L Sbjct: 62 HTYDWLEKWNEKEKLYSTSTEKLYGLAEYYVEDIQQPISNAIEEFSMSQVVSKEILDELL 121 Query: 127 QLYESASEACRNLLQEGMDSGYLVKGDLDNYVIVVSGLLEGVARVSEIMAAAKAPEDIMQ 186 L + L++ G+ SG + D + + +V+GLL G+ ++ +++ + Sbjct: 122 ALTRESYVMVEKLIEAGIQSGEFQEDDTRDLMYIVNGLLSGLG----VLYYELDYKELKR 177 Query: 187 YYREAIGLLLQGIRA 201 Y++AI +LL+G+ A Sbjct: 178 IYKKAIDVLLKGMAA 192 >C2XNW2.1 C2XNW2_BACCE Transcriptional regulator, TetR Length = 195 Score = 137 bits (345), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 72/195 (36%), Positives = 112/195 (57%), Gaps = 4/195 (2%) Query: 7 RSDGEETKKRIVQKAAQLFVQKGYGAVTMNEVCSAAKVSKGSLYHHFPSKDELFLYVVED 66 R EE KK I KA LF QKGY A +M E+C + SKGS+Y+HF SK+ELFL+VV+ Sbjct: 4 RRSAEEIKKEIAYKAESLFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQ 63 Query: 67 DTEQWLSQWAEKSRSISGLEERFYALGEHYANDFQNPLIRALEEYARARPHSDEVHQRLA 126 T WL +W EK + S E+ Y L E+Y D Q P+ A+EE++ ++ S E+ L Sbjct: 64 HTYDWLEKWNEKEKLYSTSTEKLYGLAEYYVEDIQQPISNAIEEFSMSQVVSKEILDELL 123 Query: 127 QLYESASEACRNLLQEGMDSGYLVKGDLDNYVIVVSGLLEGVARVSEIMAAAKAPEDIMQ 186 L + L++ G+ SG + D + + +V+GLL G+ ++ +++ + Sbjct: 124 ALTRESYVMVEKLIEAGIQSGEFQEDDTRDLMYIVNGLLSGLG----VLYYELDYKELKR 179 Query: 187 YYREAIGLLLQGIRA 201 Y++AI +LL+G+ A Sbjct: 180 IYKKAIDVLLKGMAA 194 >C3BFI9.1 C3BFI9_9BACI Transcriptional regulator, TetR Length = 194 Score = 137 bits (344), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 70/195 (35%), Positives = 113/195 (57%), Gaps = 4/195 (2%) Query: 7 RSDGEETKKRIVQKAAQLFVQKGYGAVTMNEVCSAAKVSKGSLYHHFPSKDELFLYVVED 66 R EE KK I +A +LF QKGY A +M ++C + SKGS+Y+HF SK+ELFL+VV+ Sbjct: 2 RKSAEEIKKEIAYQAEELFSQKGYAATSMEDICEITERSKGSIYYHFKSKEELFLFVVKQ 61 Query: 67 DTEQWLSQWAEKSRSISGLEERFYALGEHYANDFQNPLIRALEEYARARPHSDEVHQRLA 126 T WL +W EK + E+ Y L E++ D Q P+ A+EE++ ++ S E + Sbjct: 62 HTYDWLEKWNEKEKHYHTSTEKLYGLAEYHVEDIQQPIFSAVEEFSTSQIVSKETLDEML 121 Query: 127 QLYESASEACRNLLQEGMDSGYLVKGDLDNYVIVVSGLLEGVARVSEIMAAAKAPEDIMQ 186 L ++ L++EG+ SG +GD + + +V+GLL G+ ++ ++ + Sbjct: 122 VLARASYGVFEKLIEEGIKSGEFRQGDTRDLMYIVNGLLSGLG----VLYYELDSTEMKR 177 Query: 187 YYREAIGLLLQGIRA 201 Y++AI +LLQG+ A Sbjct: 178 IYKKAIDVLLQGMAA 192 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.133 0.377 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,152,528,913 Number of extensions: 44090491 Number of successful extensions: 152865 Number of sequences better than 1.0e-05: 812 Number of HSP's gapped: 153340 Number of HSP's successfully gapped: 812 Length of query: 202 Length of database: 3,060,696,203 Length adjustment: 129 Effective length of query: 73 Effective length of database: 1,845,385,268 Effective search space: 134713124564 Effective search space used: 134713124564 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 128 (53.9 bits)