BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0251.0037.p (410 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C3B5N7.1 C3B5N7_BACMY Cytochrome P450 622 e-176 C3ANA5.1 C3ANA5_BACMY Cytochrome P450 618 e-175 C3VHQ6.1 C3VHQ6_BACCE Cytochrome P450 478 e-133 C2R8M2.1 C2R8M2_BACCE Cytochrome P450 478 e-133 C2X4N0.1 C2X4N0_BACCE Cytochrome P450 478 e-133 >C3B5N7.1 C3B5N7_BACMY Cytochrome P450 Length = 409 Score = 622 bits (1603), Expect = e-176, Method: Compositional matrix adjust. Identities = 294/402 (73%), Positives = 337/402 (83%) Query: 6 MNAYRQVILLNEISKLATKQAQWEPYAWYKDMRDRNPVYYDAEQDVWNVFSYDHVKRVLF 65 M + VIL+NEISKL TK+ W PYAWY+ MR+ +PV+YDAEQDVWNVF Y+H KRVLF Sbjct: 1 MKSPENVILINEISKLKTKEELWNPYAWYQYMRENHPVFYDAEQDVWNVFLYEHAKRVLF 60 Query: 66 DHELFSNKKERSLIPTPIQLDNRSNVNLVDPPEHRKRRALLTQAFTPRSLKEWEPRIQEI 125 DH+LFSNKKERS IP P +DNRSNVN DPP+HR RRALL +AFTPRSL+ WEPRIQ I Sbjct: 61 DHQLFSNKKERSFIPIPKIMDNRSNVNFCDPPQHRNRRALLAKAFTPRSLESWEPRIQAI 120 Query: 126 VDELITNMEGAPVIDIVQKLAIPLPVTVIADLLGVPSRARGQIKAWSDILFLPYNKKAYT 185 VDEL+ +MEG +DI+QKLAIPLPV VIA+LLGVPS+ R IK+WSDILF PY K+ Y+ Sbjct: 121 VDELLIDMEGQSAVDIIQKLAIPLPVIVIAELLGVPSKDRAMIKSWSDILFFPYEKETYS 180 Query: 186 DIEQQKGRAMKEFAEFLYPIVLEKRKHPADDIISDLTQAELEGEKLTDEEVVRSAIGLLG 245 DI +K AMKEF +LYPIVLEKRKHPADDIISDLT+AELEGE+LT+EEVV SAIGLLG Sbjct: 181 DIVTKKEEAMKEFYYYLYPIVLEKRKHPADDIISDLTKAELEGERLTEEEVVISAIGLLG 240 Query: 246 AGNETTTTLISNIFYCMLFDQPGVYQELRADLSLVPKLIEEVLRFRFGATIDRKVAQDTN 305 AGNETTTTLISNIFY MLFD+PGVYQELRAD SLVPKLIEEVLRFRF +T DRKV QDT Sbjct: 241 AGNETTTTLISNIFYSMLFDKPGVYQELRADFSLVPKLIEEVLRFRFPSTNDRKVVQDTK 300 Query: 306 VFGPEMKAGQVVVAWIGAANRDESHFTRADVFDIHRPGNQQHMTFGAGPHFCLGAPLARL 365 VFG EMK GQ+V+ WIGAANRDES FT A+ FDIHR NQ H+ FG+GPHFCLGAPLAR+ Sbjct: 301 VFGHEMKQGQMVMVWIGAANRDESQFTNAEEFDIHRLENQSHLAFGSGPHFCLGAPLARM 360 Query: 366 EANMALASFVRRFPDIQQTDGFNLDEHLTASATGQSLKSLTI 407 EA +AL SFV+RF +I+Q +GF++ HLT SA GQ+LKSL I Sbjct: 361 EARIALTSFVKRFANIRQVEGFDVIHHLTDSAMGQALKSLPI 402 >C3ANA5.1 C3ANA5_BACMY Cytochrome P450 Length = 409 Score = 618 bits (1594), Expect = e-175, Method: Compositional matrix adjust. Identities = 293/402 (72%), Positives = 336/402 (83%) Query: 6 MNAYRQVILLNEISKLATKQAQWEPYAWYKDMRDRNPVYYDAEQDVWNVFSYDHVKRVLF 65 M + VIL+NEISKL TK+ W PYAWY+ MR+ +PV+YDAEQDVWNVF Y+H KRVLF Sbjct: 1 MKSPENVILINEISKLKTKEELWNPYAWYQYMRENHPVFYDAEQDVWNVFLYEHAKRVLF 60 Query: 66 DHELFSNKKERSLIPTPIQLDNRSNVNLVDPPEHRKRRALLTQAFTPRSLKEWEPRIQEI 125 DH+LFSNKKERS IP P +DNRSNVN DPP+HR RRALL +AFTPRSL+ WEPRIQ I Sbjct: 61 DHQLFSNKKERSFIPIPKIMDNRSNVNFCDPPQHRNRRALLAKAFTPRSLESWEPRIQAI 120 Query: 126 VDELITNMEGAPVIDIVQKLAIPLPVTVIADLLGVPSRARGQIKAWSDILFLPYNKKAYT 185 VDEL+ MEG +DI+QKLAIPLPV VIA+LLGVPS+ R IK+WSDILF PY K+ Y+ Sbjct: 121 VDELLIEMEGQSAVDIIQKLAIPLPVIVIAELLGVPSKDRAMIKSWSDILFFPYEKETYS 180 Query: 186 DIEQQKGRAMKEFAEFLYPIVLEKRKHPADDIISDLTQAELEGEKLTDEEVVRSAIGLLG 245 DI +K AMKEF + LYPIVLEKRKHPADDIISDLT+AELEGE+LT+EEVV SAIGLLG Sbjct: 181 DIVTKKEEAMKEFYDCLYPIVLEKRKHPADDIISDLTKAELEGERLTEEEVVISAIGLLG 240 Query: 246 AGNETTTTLISNIFYCMLFDQPGVYQELRADLSLVPKLIEEVLRFRFGATIDRKVAQDTN 305 AGNETTTTLISNIF+ MLFD+PGVYQELRAD SLVPKLIEEVLRFRF +T DRKV QDT Sbjct: 241 AGNETTTTLISNIFHSMLFDKPGVYQELRADFSLVPKLIEEVLRFRFPSTNDRKVVQDTK 300 Query: 306 VFGPEMKAGQVVVAWIGAANRDESHFTRADVFDIHRPGNQQHMTFGAGPHFCLGAPLARL 365 VFG EMK GQ+V+ WIGAANRDES FT A+ FDIHR NQ H+ FG+GPHFCLGAPLAR+ Sbjct: 301 VFGHEMKQGQMVMVWIGAANRDESQFTNAEEFDIHRLENQSHLAFGSGPHFCLGAPLARM 360 Query: 366 EANMALASFVRRFPDIQQTDGFNLDEHLTASATGQSLKSLTI 407 EA +AL SFV+RF +I+Q +GF++ HLT SA GQ+LKSL I Sbjct: 361 EARIALTSFVKRFANIRQVEGFDVIHHLTDSAMGQALKSLPI 402 >C3VHQ6.1 C3VHQ6_BACCE Cytochrome P450 Length = 404 Score = 478 bits (1231), Expect = e-133, Method: Compositional matrix adjust. Identities = 223/402 (55%), Positives = 299/402 (74%), Gaps = 3/402 (0%) Query: 6 MNAYRQVILLNEISKLATKQAQWEPYAWYKDMRDRNPVYYDAEQDVWNVFSYDHVKRVLF 65 M + VIL++EISKL TK+ W PY WY+ MRD +PV+YD EQDVWNVF YD V RVL Sbjct: 1 MASPENVILVHEISKLKTKEELWNPYEWYRLMRDNHPVHYDEEQDVWNVFLYDDVNRVLS 60 Query: 66 DHELFSNKKERSLIPTPIQLDNRSNVNLVDPPEHRKRRALLTQAFTPRSLKEWEPRIQEI 125 D+ LFS+++ER P L+ R N+N DPPEHR R+++++AFTPRSL++W+PRIQ I Sbjct: 61 DYRLFSSRRERRQFSIP-PLETRININSTDPPEHRNVRSIVSKAFTPRSLEQWKPRIQAI 119 Query: 126 VDELITNMEGAPVIDIVQKLAIPLPVTVIADLLGVPSRARGQIKAWSDILFLPYNKKAYT 185 DEL+ ++E ++IV++ A PLPVTVI+DLLGVP+ R +IK WSDILF+PY+K+ + Sbjct: 120 ADELVQHIEKCSEVNIVEQFAAPLPVTVISDLLGVPTTDRKKIKEWSDILFMPYSKEKFN 179 Query: 186 DIEQQKGRAMKEFAEFLYPIVLEKRKHPADDIISDLTQAELEGEKLTDEEVVRSAIGLLG 245 D++ +KG A+ EF +L PIV EKR H DDIISDL +AE EGE+LTDEE+V ++GLL Sbjct: 180 DLDAEKGIALNEFKAYLLPIVQEKRYHLTDDIISDLIRAEYEGERLTDEEIVTFSLGLLA 239 Query: 246 AGNETTTTLISNIFYCMLFDQPGVYQELRADLSLVPKLIEEVLRFRFGATIDRKVAQDTN 305 AGNETTT LI N FYC L D PG+Y+ELR + +L+ K IEEVLR+RF T+ R++ +DTN Sbjct: 240 AGNETTTNLIINSFYCFLVDSPGIYEELRKEPNLISKAIEEVLRYRFPVTLARRITEDTN 299 Query: 306 VFGPEMKAGQVVVAWIGAANRDESHFTRADVFDIHRPGNQQHMTFGAGPHFCLGAPLARL 365 +FGP MK Q++VAW+ AAN DE F++A F++HR GN++H+TFG GPHFCLGAPLARL Sbjct: 300 IFGPLMKKDQMIVAWVSAANLDEKKFSQASQFNVHRTGNEEHLTFGKGPHFCLGAPLARL 359 Query: 366 EANMALASFVRRFPDIQQTDGFNLDEHLTASATGQSLKSLTI 407 EA +AL +F+ F I+ + F L++ + + Q+LK L I Sbjct: 360 EAEIALTTFINTFEKIELSPSFCLEKCILENE--QTLKYLPI 399 >C2R8M2.1 C2R8M2_BACCE Cytochrome P450 Length = 404 Score = 478 bits (1231), Expect = e-133, Method: Compositional matrix adjust. Identities = 223/402 (55%), Positives = 299/402 (74%), Gaps = 3/402 (0%) Query: 6 MNAYRQVILLNEISKLATKQAQWEPYAWYKDMRDRNPVYYDAEQDVWNVFSYDHVKRVLF 65 M + VIL++EISKL TK+ W PY WY+ MRD +PV+YD EQDVWNVF YD V RVL Sbjct: 1 MASPENVILVHEISKLKTKEELWNPYEWYRLMRDNHPVHYDEEQDVWNVFLYDDVNRVLS 60 Query: 66 DHELFSNKKERSLIPTPIQLDNRSNVNLVDPPEHRKRRALLTQAFTPRSLKEWEPRIQEI 125 D+ LFS+++ER P L+ R N+N DPPEHR R+++++AFTPRSL++W+PRIQ I Sbjct: 61 DYRLFSSRRERRQFSIP-PLETRININSTDPPEHRNVRSIVSKAFTPRSLEQWKPRIQAI 119 Query: 126 VDELITNMEGAPVIDIVQKLAIPLPVTVIADLLGVPSRARGQIKAWSDILFLPYNKKAYT 185 DEL+ ++E ++IV++ A PLPVTVI+DLLGVP+ R +IK WSDILF+PY+K+ + Sbjct: 120 ADELVQHIEKCSEVNIVEQFAAPLPVTVISDLLGVPTTDRKKIKEWSDILFMPYSKEKFN 179 Query: 186 DIEQQKGRAMKEFAEFLYPIVLEKRKHPADDIISDLTQAELEGEKLTDEEVVRSAIGLLG 245 D++ +KG A+ EF +L PIV EKR H DDIISDL +AE EGE+LTDEE+V ++GLL Sbjct: 180 DLDAEKGIALNEFKAYLLPIVQEKRYHLTDDIISDLIRAEYEGERLTDEEIVTFSLGLLA 239 Query: 246 AGNETTTTLISNIFYCMLFDQPGVYQELRADLSLVPKLIEEVLRFRFGATIDRKVAQDTN 305 AGNETTT LI N FYC L D PG+Y+ELR + +L+ K IEEVLR+RF T+ R++ +DTN Sbjct: 240 AGNETTTNLIINSFYCFLVDSPGIYEELRKEPNLISKAIEEVLRYRFPVTLARRITEDTN 299 Query: 306 VFGPEMKAGQVVVAWIGAANRDESHFTRADVFDIHRPGNQQHMTFGAGPHFCLGAPLARL 365 +FGP MK Q++VAW+ AAN DE F++A F++HR GN++H+TFG GPHFCLGAPLARL Sbjct: 300 IFGPLMKKDQMIVAWVSAANLDEKKFSQASQFNVHRTGNEKHLTFGKGPHFCLGAPLARL 359 Query: 366 EANMALASFVRRFPDIQQTDGFNLDEHLTASATGQSLKSLTI 407 EA +AL +F+ F I+ + F L++ + + Q+LK L I Sbjct: 360 EAEIALTTFINTFEKIELSPSFCLEKCILENE--QTLKYLPI 399 >C2X4N0.1 C2X4N0_BACCE Cytochrome P450 Length = 404 Score = 478 bits (1231), Expect = e-133, Method: Compositional matrix adjust. Identities = 225/402 (55%), Positives = 299/402 (74%), Gaps = 3/402 (0%) Query: 6 MNAYRQVILLNEISKLATKQAQWEPYAWYKDMRDRNPVYYDAEQDVWNVFSYDHVKRVLF 65 M++ VIL++EISKL TK+ W PY WY+ MRD +PV+YD EQDVWNVF Y+ V RVL Sbjct: 1 MDSPENVILVHEISKLKTKEELWNPYGWYQFMRDNHPVHYDEEQDVWNVFLYEDVNRVLS 60 Query: 66 DHELFSNKKERSLIPTPIQLDNRSNVNLVDPPEHRKRRALLTQAFTPRSLKEWEPRIQEI 125 D+ LFS+++ER P L+ R N+N DPPEHR R+++++AFTPRSL++W+PRIQ I Sbjct: 61 DYRLFSSRRERRQFAIP-PLETRININSTDPPEHRNVRSIVSKAFTPRSLEQWKPRIQAI 119 Query: 126 VDELITNMEGAPVIDIVQKLAIPLPVTVIADLLGVPSRARGQIKAWSDILFLPYNKKAYT 185 DEL+ N++ ++IV + A PLPVTVI+DLLGVP+ R QIK WSDILF+PY+K+ + Sbjct: 120 ADELVKNIKKYDEVNIVNQFAAPLPVTVISDLLGVPTTDRKQIKEWSDILFMPYSKEKFN 179 Query: 186 DIEQQKGRAMKEFAEFLYPIVLEKRKHPADDIISDLTQAELEGEKLTDEEVVRSAIGLLG 245 D++ +KG A+ EF +L PIV EKR H DDIISDL +AE EGE+LTDEE+V ++GLL Sbjct: 180 DLDAEKGIALNEFKAYLLPIVQEKRYHLTDDIISDLIRAEYEGERLTDEEIVTFSLGLLA 239 Query: 246 AGNETTTTLISNIFYCMLFDQPGVYQELRADLSLVPKLIEEVLRFRFGATIDRKVAQDTN 305 AGNETTT LI N FYC L D PG+YQELR + LV K IEEVLR+RF T+ R++ +DTN Sbjct: 240 AGNETTTNLIINCFYCFLVDSPGIYQELREEPKLVAKAIEEVLRYRFPVTLARRITEDTN 299 Query: 306 VFGPEMKAGQVVVAWIGAANRDESHFTRADVFDIHRPGNQQHMTFGAGPHFCLGAPLARL 365 +FGP MK Q++VAW+ AAN DE+ F+ A +++HR GN++H+TFG GPHFCLGAPLARL Sbjct: 300 IFGPLMKKDQMIVAWVSAANLDENKFSHASKYNLHRIGNEKHLTFGKGPHFCLGAPLARL 359 Query: 366 EANMALASFVRRFPDIQQTDGFNLDEHLTASATGQSLKSLTI 407 EA +AL++F+ F I+ + FNL+ + + Q+LK L I Sbjct: 360 EAEIALSTFINAFEKIELSPFFNLERCILKNE--QTLKYLPI 399 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.136 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,461,911,779 Number of extensions: 103857725 Number of successful extensions: 282540 Number of sequences better than 1.0e-05: 2610 Number of HSP's gapped: 275287 Number of HSP's successfully gapped: 2636 Length of query: 410 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 272 Effective length of database: 1,760,596,133 Effective search space: 478882148176 Effective search space used: 478882148176 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 132 (55.5 bits)