BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0251.0021.p (527 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DGT9.1 B1DGT9_9BACL Two component transcriptional regulator, A... 706 0.0 B1D5Z5.1 B1D5Z5_9BACL Two component transcriptional regulator, A... 223 4e-56 B1D4P3.1 B1D4P3_9BACL Two component transcriptional regulator, A... 206 4e-51 B3KJG1.1 B3KJG1_9BACI Response regulator receiver 199 6e-49 A9QDR4.1 A9QDR4_9BACL YesN 196 5e-48 >B1DGT9.1 B1DGT9_9BACL Two component transcriptional regulator, AraC family Length = 527 Score = 706 bits (1823), Expect = 0.0, Method: Compositional matrix adjust. Identities = 331/527 (62%), Positives = 428/527 (81%) Query: 1 VRLVLIDDEKGIVEGLKKIIGRYLPECKVVGEAYNGLEGFELIQRLRPDIVITDIRMPVA 60 +RL+L+DDEKGIV+GLKK+I RY+PEC+VVG A+NG+EG +LIQ+++PDIVITDIRMP A Sbjct: 1 MRLILVDDEKGIVDGLKKMISRYIPECEVVGTAHNGVEGSKLIQKIKPDIVITDIRMPQA 60 Query: 61 DGLDMIKMLEDNKIQTKFILLSGYADFEYARRGMKLGVQFYINKPVEEEELHDSVNRVME 120 DGLDMI M+++ +QTKFILLSGYADFEYARRGM+LGVQFYINKPVEEEEL D + M+ Sbjct: 61 DGLDMIHMVQEAGVQTKFILLSGYADFEYARRGMQLGVQFYINKPVEEEELRDCLYTAMK 120 Query: 121 TIRADRSKLQRLNELKHEVHSRMQEETLRDILDLGNEHTSLVEELLHSAQIPTAGTWFNS 180 T++A+++K + +++LK EVHS MQE LRD+LD+G+E ++EELL A+IP+AG WF Sbjct: 121 TVQAEKAKRREVDDLKQEVHSLMQENALRDLLDIGSEKEEVIEELLQIARIPSAGIWFGC 180 Query: 181 IIIEIEGSTELLKEIGFQPLLQHIDQTLRNYYKVYRFRYFGPQIAIVIAHNSNIVYGRLL 240 +++E GS + L++ Q +L IDQ L Y VYRFRY QIA++++ +I Y L+ Sbjct: 181 MLLEFYGSADTLRDSVIQQVLDQIDQNLGKYRAVYRFRYSSTQIAVIVSQGRSIGYADLV 240 Query: 241 HVIQGLRQAVYQKLNLSISVGIGTVYKRGTGICQSFEEARNALSYKLIKEGNPVISFTEI 300 + L++ VYQ LS++VGIGTV K GI SFE+AR+ALSYK+IK N VI+ EI Sbjct: 241 SSVHRLKEQVYQHYELSMTVGIGTVQKGAAGISLSFEQARHALSYKVIKGANAVIAHPEI 300 Query: 301 KKITEHSHPVPEELITRLEDGLDNMDEEECVAVIREMFRGMAAESGMNPADLQLRCLNIL 360 +T S PVPEE+IT+LE L+N+DE+E +++IR++FR M A SGM+P DLQL+CLNIL Sbjct: 301 HNLTGRSEPVPEEMITKLEAALENLDEKEGISIIRDIFRKMEARSGMSPTDLQLQCLNIL 360 Query: 361 LSSIRKLSFQQLQQNELVGRHILSLEGFSRFRTLEYLEEWMIQVIRGIINFKVEHNLSQK 420 LSS+RK+SF+QLQQN+ +GRHILSLEG SRF+TLE LEEWM QVIR II FK EHN+ +K Sbjct: 361 LSSVRKMSFRQLQQNDFLGRHILSLEGMSRFQTLESLEEWMAQVIRKIIVFKQEHNIPKK 420 Query: 421 KDIISEIKLYVSKHFNEQISLADLAARFFISPYYLSQLFKRKTGDNYLNFLTQMRIDKAK 480 KDII+E+K YV++H++E I+LADL+ARFFISPYYLSQ FK+KTGD Y+NFLT++RI+KAK Sbjct: 421 KDIIAEVKEYVAEHYSEPITLADLSARFFISPYYLSQFFKQKTGDTYVNFLTRIRINKAK 480 Query: 481 ELLENTDLKVYEICRMVGYLDAQHFSRMFEKLAGCKPREYRKNLPNS 527 ELLE TDLKVYE+C+MVGY D QHF+RMFEKL G KPR+YRK LPN+ Sbjct: 481 ELLERTDLKVYEVCQMVGYSDTQHFARMFEKLTGYKPRDYRKRLPNA 527 >B1D5Z5.1 B1D5Z5_9BACL Two component transcriptional regulator, AraC family Length = 535 Score = 223 bits (568), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 163/547 (29%), Positives = 282/547 (51%), Gaps = 41/547 (7%) Query: 1 VRLVLIDDEKGIVEGLKKIIGRYLPECKVVGEAYNGLEGFELIQRLRPDIVITDIRMPVA 60 + L+++DDE I +G++ I +VVGEA +G+EG E +L+P I +TDIRMP+ Sbjct: 2 ITLLIVDDEPNIRKGIRTSIDWEDYGIEVVGEAADGVEGLEKALKLKPHITVTDIRMPLM 61 Query: 61 DGLDMIKMLEDNKIQTKFILLSGYADFEYARRGMKLGVQFYINKPVEEEELHDSVNRVME 120 DGL++ + L++ T+ ++LSGY DF +A+ + +GVQ Y+ KPV EEL D + ++ E Sbjct: 62 DGLELSRHLKNQLPDTRIVILSGYEDFSFAKEALAIGVQDYLLKPVGAEELVDLMLKLSE 121 Query: 121 TIR---ADRSKLQRLNELKHEVHSRMQEETLRDILDLGNEHTSLVEELLHSAQIPTAGTW 177 I+ AD+ Q LN + +E + ++ + + IL G +S + + +I +G Sbjct: 122 EIKLAEADKRNRQSLNMMINENYQTIKSDFINRILQGGVTDSSAIFDKAELLKIRLSGPE 181 Query: 178 FNSIIIEIEGSTELLKEIGFQPLLQHIDQTLRNYYKVYRFRYFGPQIAIVIAHNSNIV-Y 236 ++ + I+I+ F + + + + R ++ RF ++++ +V Y Sbjct: 182 YSILAIDID---------DFALMTEDLPENKR---ELIRFSVMNIAEEVLLSRTQGLVCY 229 Query: 237 GRLLHVI-----QGLR------------QAVYQKLNLSISVGIGTVYKRGTGICQSFEEA 279 + H+I GLR QAV L LSIS+GI + S+ EA Sbjct: 230 SQFDHLIGMMSGGGLRADFVDHVCEEIQQAVKTYLKLSISIGISRNCTDIAVLSTSYAEA 289 Query: 280 RNALSYKLIKEGNPVISFTEIKKITEHS---HPVPEELITRLEDGLDNMDEEECVAVIRE 336 +AL K+ K +I + E TE +P EE + + L ++ E + I + Sbjct: 290 FSALKAKIHKGKGSLIRYQESMMSTEMQNVLYPSEEEKV--IIGCLKTLNSSELHSAIDQ 347 Query: 337 MFRGMAAESGMNPADLQLRCLNILLSSIRKLSFQQLQQNELVGRHILSLEGFSRFRTLEY 396 +F AA P ++ C +LL ++ + + ++G + RF TL Sbjct: 348 IFDRFAAGQTDAPV-IRSICGRLLLMAVSGVEEMSVDVGSIIGTNFNPYREMERFDTLGD 406 Query: 397 LEEWMIQVIRGIINFKVEHNLSQK-KDIISEIKLYVSKHFNEQISLADLAARFFISPYYL 455 L +WM V+ + V+ N +QK K +I Y+ +++N +SLAD+AA +++P YL Sbjct: 407 LRKWMNDVLHRLSEL-VQENKNQKFKGVIKTALRYMEENYNRAVSLADVAAIVYVTPNYL 465 Query: 456 SQLFKRKTGDNYLNFLTQMRIDKAKELLENTDLKVYEICRMVGYLDAQHFSRMFEKLAGC 515 S++FK + G N++ +L + RI+KAK LL K Y + VGY D ++FS+MF++ A C Sbjct: 466 SRIFKEEIGVNFVEWLNRYRIEKAKLLLSEPGAKTYAVAEKVGYSDYKYFSQMFKRFADC 525 Query: 516 KPREYRK 522 P+EY++ Sbjct: 526 SPKEYKE 532 >B1D4P3.1 B1D4P3_9BACL Two component transcriptional regulator, AraC family Length = 538 Score = 206 bits (525), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 155/539 (28%), Positives = 265/539 (49%), Gaps = 32/539 (5%) Query: 3 LVLIDDEKGIVEGLKKIIGRYLPECKVVGEAYNGLEGFELIQRLRPDIVITDIRMPVADG 62 ++L+DDE + EG+++ I + V + NG++ E I+RLRP IV+TDI MP DG Sbjct: 4 ILLVDDEAVVREGIRERIPWEELGFRCVADCENGVQALEEIERLRPHIVLTDINMPFMDG 63 Query: 63 LDMIKMLEDNKIQTKFILLSGYADFEYARRGMKLGVQFYINKPVEEEELHDSVNRV---M 119 L + + + + +TK ++L+GY DFEYA++ +KL V+ +I KPV E ++++ + Sbjct: 64 LALSREVMERYPETKVVILTGYDDFEYAQQALKLKVKDFILKPVTAAEFSAMLHKLRLEL 123 Query: 120 ETIRADRSKLQRLNELKHEVHSRMQEETLRDILDLGNEHTSLVEELLHSAQIPTAGTWFN 179 + + +R L RL HE ++E L + + + LH QI G + Sbjct: 124 DEEKREREDLARLQSQLHESMPLLKERFLERMSTMALTEKEIASR-LHYFQIQLKGPCYL 182 Query: 180 SIII-----EIEGSTELLKEIGFQPLLQHIDQTLRNYYKVYRFRYFGPQI-AIVIAHNSN 233 + I E +G + +E+ + + + FR ++ A++ Sbjct: 183 GLAIDTDRLEEQGGADTDRELLRFAVYNIAQEIISGEPGAVVFRSREERVMAVLGGEREE 242 Query: 234 IVYGRLLHVIQGLRQAVYQKLNLSISVGIGTVYKRGTGICQSFEEARNALSYKLIKEGNP 293 ++ + + + +RQ+ Q L L++SVGIG TGI ++ + A AL Y+L+ N Sbjct: 243 LLQEKAQELAERIRQSAVQFLKLTVSVGIGMTVHSYTGIRETCKAAAAALDYRLVLGDNS 302 Query: 294 VISFTEIKK--ITEHSHPV--PEELITRLEDGLDNMDEEECVAVIREMFRGMAAESGMNP 349 VIS +++K + HP ELI ++ G + E A+IR N Sbjct: 303 VISILDMEKRRSSPAGHPAQFDRELIAGIKTGTADEVERAIEALIR-----------YNK 351 Query: 350 ADLQ------LRCLNILLSSIRKLSFQQLQQNELVGRHILSLEGFSRFRTLEYLEEWMIQ 403 A+L LR +L+ ++ L +++E+ G + + RFRT+E + EW+ Sbjct: 352 AELTSIDHCYLRIQRTILAVMQALGDIGCKESEVFGEGVNPMTEIYRFRTMEEIGEWLKT 411 Query: 404 VIRGIINFKVEHNLSQKKDIISEIKLYVSKHF-NEQISLADLAARFFISPYYLSQLFKRK 462 R ++ Q + I E Y+ H+ +E +S+ + + +S Y S FK Sbjct: 412 ACRQAVHSVTATRHDQCRSQIEEAIAYLESHYEDENLSVKAVCKQVHMSVSYFSAAFKSH 471 Query: 463 TGDNYLNFLTQMRIDKAKELLENTDLKVYEICRMVGYLDAQHFSRMFEKLAGCKPREYR 521 TG ++ + T +R+DKAKELL+ T L+ YEI GY DAQ+FS +F+K G P +YR Sbjct: 472 TGRTFIEYATAVRMDKAKELLKFTGLRTYEIAARTGYSDAQYFSVLFKKHTGESPTDYR 530 >B3KJG1.1 B3KJG1_9BACI Response regulator receiver Length = 539 Score = 199 bits (506), Expect = 6e-49, Method: Compositional matrix adjust. Identities = 148/547 (27%), Positives = 279/547 (51%), Gaps = 39/547 (7%) Query: 3 LVLIDDEKGIVEGLKKIIGRYLPECKVVGEAYNGLEGFELIQRLRPDIVITDIRMPVADG 62 ++++DDE + EG++ I + +G+ NG + E + R +PD+V+TDI MP DG Sbjct: 4 ILIVDDEPIVREGIRNRIQWSEHGYECIGDCENGRDALEAVTRHQPDVVLTDINMPYMDG 63 Query: 63 LDMIKMLEDNKIQTKFILLSGYADFEYARRGMKLGVQFYINKPVEEEELHDSVNRVMETI 122 L++ + + + +TK I+L+G+ DFEYA++ +KL V +I KPV EL D ++++ + Sbjct: 64 LELSRHITERFPKTKIIILTGFDDFEYAQQAVKLQVTDFILKPVTAAELRDMLDKLKLEM 123 Query: 123 RADRSKLQRLNELKHEVHSRMQ--EETLRDILDLGNEHTSLVEELLHSAQIPTAGTWFNS 180 +R + L LK +++ + E + L S +E L IP G + + Sbjct: 124 DEERGHTEHLKRLKKQLNESLVLLRERFLERLASSPMKRSEMESRLDYFDIPLRGPLYIA 183 Query: 181 IIIEIEGSTELLKEIGFQPLLQHIDQTLRNY--YKVYR-----------FRYFGPQIAIV 227 + +++ EL + QH D L + Y + + FRY ++ + Sbjct: 184 MAADMD---ELRSD------EQHADNELHAFALYNIMQEILAGEPGAAVFRYKENKVMTI 234 Query: 228 IA-HNSNIVYGRLLHVIQGLRQAVYQKLNLSISVGIGTVYKRGTGICQSFEEARNALSYK 286 ++ + ++ R + + +R + Q + +++VGIGT+ + I S + + AL Y+ Sbjct: 235 LSGSDEKDLHARAQELAEDIRGSTKQFMKFTVTVGIGTICRELQDIRYSCKASEAALEYR 294 Query: 287 LIKEGNPVISFTEIKKITEHSHPVPE--ELITRLEDGLDNMDEEECVAVIREMFRGMAAE 344 L+ + V+ T+++K S P+ + E T L + E A IR + + + Sbjct: 295 LLIGRDQVVHITDLEK--RGSGPLLDGIETETALVSAIRAGTGSEVKACIRRLINEIGSA 352 Query: 345 SGMNPADLQLRCLNILLSSIRKLSFQQLQQNELVGRHILSLEGFSRFRTLEYLEEWMIQV 404 S ++ +R L ++L+ ++ L NEL+G+ L FR+L+ +E W+ +V Sbjct: 353 S-ISIELCYVRVLRVMLAVLQTLMEIGSNGNELIGKEKRLLSDLYSFRSLDEIERWLNEV 411 Query: 405 ----IRGIINFKVEHNLSQKKDIISEIKLYVSKHF-NEQISLADLAARFFISPYYLSQLF 459 +R + + + SQ + + ++ +H+ +E++S+ + +R F+S Y S LF Sbjct: 412 CEQALRDVAKTRKDIARSQMLEAVD----FIQRHYEDEELSIKTVCSRIFMSTSYFSALF 467 Query: 460 KRKTGDNYLNFLTQMRIDKAKELLENTDLKVYEICRMVGYLDAQHFSRMFEKLAGCKPRE 519 K TG ++ ++T++R++KAKELL+++ LK YEI GY D Q+FS +F+K G P E Sbjct: 468 KSHTGKTFVEYVTEVRMEKAKELLKHSLLKTYEIAAKTGYQDPQYFSVLFKKHTGDTPTE 527 Query: 520 YRKNLPN 526 YR + Sbjct: 528 YRNKMAT 534 >A9QDR4.1 A9QDR4_9BACL YesN Length = 522 Score = 196 bits (498), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 156/546 (28%), Positives = 271/546 (49%), Gaps = 53/546 (9%) Query: 2 RLVLIDDEKGIVEGLKKIIGRYLPECKVVGEAYNGLEGFELIQRLRPDIVITDIRMPVAD 61 +++L+DDE + +GL+ +I ++ EA NG E E IQ ++PD+VI DIRMPV D Sbjct: 3 KVLLVDDEIFVRKGLRNLIDWESLGYEICDEAGNGQEALEKIQLIKPDLVIADIRMPVLD 62 Query: 62 GLDMIKMLEDNKIQT-KFILLSGYADFEYARRGMKLGVQFYINKPVEEEELHDSVNRVME 120 GL++I+ + + + + FI++SGY DF+YA+R ++ GV YI KP++E EL ++ + Sbjct: 63 GLELIRKVTEEGVHSPTFIIVSGYHDFQYAQRALRYGVHDYILKPIDEAELETTLKALSG 122 Query: 121 TIRADRSKLQRLNELKHEVHSRMQEETLRDILDLGNEHTSLVEELLHSAQIPTAGTWFNS 180 T+ L +L + +++ + L G + L + Q+P + F+ Sbjct: 123 TLG--------LKKLATIAGDSLVTDSIVETLVQGQFSEADNGALCAALQMPEFSS-FDY 173 Query: 181 IIIEIEGSTELL------KEIGFQPLLQHIDQTLRNYYKVY------------RFRYFGP 222 +++E+ S + KE+ ++Q + T + VY R + P Sbjct: 174 VLVELHASAQSAGTEWQAKELA--AVVQSVSATPSSKIPVYEQTSGLFGLLIDRKPFLPP 231 Query: 223 QIAIVIAHNSNIVYGRLLHVIQGLRQAVYQKLNLSISVGIGTVYKRGTGICQSFEEARNA 282 +I + A+NS L A+ + +++ IG +R +C S+ A A Sbjct: 232 EIRLESAYNS-------------LHAAIAKSSGRPVTLYIGKTVERLQEMCLSYRAANEA 278 Query: 283 LSYKLIKEGNPVISFTEIKKITEHSHPVPEELITRLEDGLDNMDEEECVAVIREMFRGMA 342 +SYK ++G+ VI +++ + V EL +RL + L+ + + I +FR Sbjct: 279 MSYKYAEQGSSVIYANQVQGTPLYYFDVDSELYSRLLERLEENNADLYEQDIELLFRQFV 338 Query: 343 AESGMNP---ADLQLRCLNILLSSIRKLSFQQLQQNELVGRHILSLEGF-SRFRTLEYLE 398 E P A+ R + +++ IRK+ + ++L I+ +G SR + L+ L Sbjct: 339 -EKRFAPNAVANTITRFVIGIINIIRKMEGDEKGLSKL--PFIMDWQGSNSRLQDLKGL- 394 Query: 399 EWMIQVIRGIINFKVEHNLSQKKDIISEIKLYVSKHFNEQISLADLAARFFISPYYLSQL 458 +R + E Q K I IK Y+ ++ E ISL +A +F+++ YL QL Sbjct: 395 --FTDFLREAAVYLAELRNEQSKGGIERIKKYIEANYTENISLKSIAGKFYMNSVYLGQL 452 Query: 459 FKRKTGDNYLNFLTQMRIDKAKELLENTDLKVYEICRMVGYLDAQHFSRMFEKLAGCKPR 518 F++ G + +FL Q+RI +AK+LL TDL++YEI VG+ +A +F FEKL P Sbjct: 453 FRKTYGIYFNDFLLQIRIGEAKKLLRQTDLRMYEIAEKVGFQNADYFVTQFEKLEKVTPT 512 Query: 519 EYRKNL 524 +YR L Sbjct: 513 DYRNKL 518 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.322 0.139 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,986,956,357 Number of extensions: 124464346 Number of successful extensions: 440156 Number of sequences better than 1.0e-05: 10598 Number of HSP's gapped: 449336 Number of HSP's successfully gapped: 11172 Length of query: 527 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 386 Effective length of database: 1,732,333,088 Effective search space: 668680571968 Effective search space used: 668680571968 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 134 (56.2 bits)