BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0251.0010.p (318 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q4U1W0.1 Q4U1W0_9BACL Sensor protein EC=2.7.13.3 277 9e-73 B9DXU1.1 B9DXU1_CLOK1 Sensor protein EC=2.7.13.3 274 7e-72 A5N472.1 A5N472_CLOK5 Sensor protein EC=2.7.13.3 274 7e-72 Q4U1W7.1 Q4U1W7_PANTH Sensor protein EC=2.7.13.3 273 1e-71 Q9RMA3.1 Q9RMA3_BACCI Sensor protein EC=2.7.13.3 271 4e-71 >Q4U1W0.1 Q4U1W0_9BACL Sensor protein EC=2.7.13.3 Length = 388 Score = 277 bits (709), Expect = 9e-73, Method: Compositional matrix adjust. Identities = 145/292 (49%), Positives = 193/292 (66%), Gaps = 1/292 (0%) Query: 2 NYAKLRMKVFVRMXXXXXXXXXXXXXXYSLVRGRLGEAGVRLLQYVFGYEYDHALSIYES 61 +Y+KL+ K++ + ++G LGE VR L+ + E A+ IY+ Sbjct: 15 DYSKLKRKLYQYIVVIVMAAAVFVLFLRLFIKGTLGEWIVRFLENSYHLERQDAMIIYQY 74 Query: 62 VLRDHWEXXXXXXXXXXXXXXXXXXXXWFTKYFNEVNAGIDALITDE-ADIKLSPEMSSM 120 +R++ E F KYF+E+N GID LI +E I+LS EM M Sbjct: 75 TIRNNIEIFIYVAIAISILILCRVMLSKFAKYFDEINTGIDILIQNEDKQIELSAEMEFM 134 Query: 121 EQKLVFVKQTLQKRELEVQLSEQNKRDLVMYLAHDIKTPLTSVIGYLSLLHEAPDMPNEQ 180 EQKL +K+TL+KRE + +L+EQ K D+VMYLAHDIKTPLTSVIGYLSLL EAPDMP EQ Sbjct: 135 EQKLNTLKRTLEKREQDAKLAEQRKNDVVMYLAHDIKTPLTSVIGYLSLLDEAPDMPVEQ 194 Query: 181 KENYTKITLEKAYHLERLINDFFEVERYNQQTIQLKKQNVDLSYMLIQMPDEFYPSLTPA 240 K Y ITL+KAY LE+LI++FFE+ RYN QTI L K+++DL YML+QM DEFYP L Sbjct: 195 KAKYVHITLDKAYRLEQLIDEFFEITRYNLQTITLTKKHIDLYYMLVQMADEFYPQLAAN 254 Query: 241 GKRMIVNVEDTITVYGDSEKLARVFNNILKNAIAYSDDNSTIEVSAKVQKDM 292 GK+ +++ + +TV GDS+KLARVFNNILKNA AYS+DNS I+++A + D+ Sbjct: 255 GKQAVIHASEDLTVTGDSDKLARVFNNILKNAAAYSEDNSVIDITAGLSGDV 306 >B9DXU1.1 B9DXU1_CLOK1 Sensor protein EC=2.7.13.3 Length = 388 Score = 274 bits (701), Expect = 7e-72, Method: Compositional matrix adjust. Identities = 146/289 (50%), Positives = 190/289 (65%), Gaps = 1/289 (0%) Query: 2 NYAKLRMKVFVRMXXXXXXXXXXXXXXYSLVRGRLGEAGVRLLQYVFGYEYDHALSIYES 61 +Y KL+ KVF +M ++RG++G VR L F ++ A +IY+ Sbjct: 15 DYTKLKRKVFFQMLMITVAAAVTVYLLRHILRGQIGNRIVRFLVNAFHFKNSEAQTIYQL 74 Query: 62 VLRDHWEXXXXXXXXXXXXXXXXXXXXWFTKYFNEVNAGIDALITD-EADIKLSPEMSSM 120 V+R++ + WFTKYF+EV+AG+D L + + I LSPE+ M Sbjct: 75 VIRNNMDMILFVVILIFLVILFRFSVSWFTKYFDEVSAGMDKLAEEFDEKITLSPELDFM 134 Query: 121 EQKLVFVKQTLQKRELEVQLSEQNKRDLVMYLAHDIKTPLTSVIGYLSLLHEAPDMPNEQ 180 E KL +K L+K+E +EQ K DLV+YLAHDIKTPLTSVIGYLSLL EAPDMP EQ Sbjct: 135 ENKLNQIKNNLEKQEKAALDAEQRKNDLVVYLAHDIKTPLTSVIGYLSLLDEAPDMPPEQ 194 Query: 181 KENYTKITLEKAYHLERLINDFFEVERYNQQTIQLKKQNVDLSYMLIQMPDEFYPSLTPA 240 K Y ITLEKAY LE+LIN+FFE+ R+N QTI L K ++L +ML QM DEFYP LTP Sbjct: 195 KAKYVSITLEKAYRLEQLINEFFEITRFNLQTIVLNKVKINLLFMLQQMADEFYPILTPQ 254 Query: 241 GKRMIVNVEDTITVYGDSEKLARVFNNILKNAIAYSDDNSTIEVSAKVQ 289 K++ VNV D +T++GD++K+ARVFNNILKNAIAYS +NS I++SAK Q Sbjct: 255 EKQVSVNVPDGLTLWGDADKMARVFNNILKNAIAYSYENSIIDISAKQQ 303 >A5N472.1 A5N472_CLOK5 Sensor protein EC=2.7.13.3 Length = 384 Score = 274 bits (701), Expect = 7e-72, Method: Compositional matrix adjust. Identities = 146/289 (50%), Positives = 190/289 (65%), Gaps = 1/289 (0%) Query: 2 NYAKLRMKVFVRMXXXXXXXXXXXXXXYSLVRGRLGEAGVRLLQYVFGYEYDHALSIYES 61 +Y KL+ KVF +M ++RG++G VR L F ++ A +IY+ Sbjct: 11 DYTKLKRKVFFQMLMITVAAAVTVYLLRHILRGQIGNRIVRFLVNAFHFKNSEAQTIYQL 70 Query: 62 VLRDHWEXXXXXXXXXXXXXXXXXXXXWFTKYFNEVNAGIDALITD-EADIKLSPEMSSM 120 V+R++ + WFTKYF+EV+AG+D L + + I LSPE+ M Sbjct: 71 VIRNNMDMILFVVILIFLVILFRFSVSWFTKYFDEVSAGMDKLAEEFDEKITLSPELDFM 130 Query: 121 EQKLVFVKQTLQKRELEVQLSEQNKRDLVMYLAHDIKTPLTSVIGYLSLLHEAPDMPNEQ 180 E KL +K L+K+E +EQ K DLV+YLAHDIKTPLTSVIGYLSLL EAPDMP EQ Sbjct: 131 ENKLNQIKNNLEKQEKAALDAEQRKNDLVVYLAHDIKTPLTSVIGYLSLLDEAPDMPPEQ 190 Query: 181 KENYTKITLEKAYHLERLINDFFEVERYNQQTIQLKKQNVDLSYMLIQMPDEFYPSLTPA 240 K Y ITLEKAY LE+LIN+FFE+ R+N QTI L K ++L +ML QM DEFYP LTP Sbjct: 191 KAKYVSITLEKAYRLEQLINEFFEITRFNLQTIVLNKVKINLLFMLQQMADEFYPILTPQ 250 Query: 241 GKRMIVNVEDTITVYGDSEKLARVFNNILKNAIAYSDDNSTIEVSAKVQ 289 K++ VNV D +T++GD++K+ARVFNNILKNAIAYS +NS I++SAK Q Sbjct: 251 EKQVSVNVPDGLTLWGDADKMARVFNNILKNAIAYSYENSIIDISAKQQ 299 >Q4U1W7.1 Q4U1W7_PANTH Sensor protein EC=2.7.13.3 Length = 386 Score = 273 bits (698), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 140/263 (53%), Positives = 182/263 (69%), Gaps = 1/263 (0%) Query: 31 LVRGRLGEAGVRLLQYVFGYEYDHALSIYESVLRDHWEXXXXXXXXXXXXXXXXXXXXWF 90 ++G LGE VR L+ + E A+ IY+ +R++ E F Sbjct: 42 FIKGTLGEWIVRFLENSYHLERQDAMKIYQYTIRNNIEIFIYVAIAISILILCRVMLSKF 101 Query: 91 TKYFNEVNAGIDALITDE-ADIKLSPEMSSMEQKLVFVKQTLQKRELEVQLSEQNKRDLV 149 KYF+E+N GID LI +E I+LS EM MEQKL +K+TL+KRE + +L+EQ K D+V Sbjct: 102 AKYFDEINTGIDILIQNEDKQIELSAEMEFMEQKLNTLKRTLEKREQDAKLAEQRKNDVV 161 Query: 150 MYLAHDIKTPLTSVIGYLSLLHEAPDMPNEQKENYTKITLEKAYHLERLINDFFEVERYN 209 MYLAHDIKTPLTSVIGYLSLL EAPDMP EQK Y ITL+KAY LE+LI++FFE+ RYN Sbjct: 162 MYLAHDIKTPLTSVIGYLSLLDEAPDMPVEQKAKYVHITLDKAYRLEQLIDEFFEITRYN 221 Query: 210 QQTIQLKKQNVDLSYMLIQMPDEFYPSLTPAGKRMIVNVEDTITVYGDSEKLARVFNNIL 269 QTI L K+++DL YML+QM DEFYP L GK+ +++ + +TV GD +KLARVFNNIL Sbjct: 222 LQTITLTKKHIDLYYMLVQMTDEFYPQLAANGKQAVIHASEDLTVSGDPDKLARVFNNIL 281 Query: 270 KNAIAYSDDNSTIEVSAKVQKDM 292 KNA AYS+DNS I+++A + D+ Sbjct: 282 KNAAAYSEDNSVIDITAGLSGDV 304 >Q9RMA3.1 Q9RMA3_BACCI Sensor protein EC=2.7.13.3 Length = 382 Score = 271 bits (694), Expect = 4e-71, Method: Compositional matrix adjust. Identities = 143/292 (48%), Positives = 192/292 (65%), Gaps = 1/292 (0%) Query: 2 NYAKLRMKVFVRMXXXXXXXXXXXXXXYSLVRGRLGEAGVRLLQYVFGYEYDHALSIYES 61 +Y+KL K+++ + S++RG+LGE VR L+ +G A+ +Y Sbjct: 9 DYSKLERKLYMYIVAIVVVAVIFVLYIRSMIRGKLGEWIVRFLENEYGLNQLDAMKLYHY 68 Query: 62 VLRDHWEXXXXXXXXXXXXXXXXXXXXWFTKYFNEVNAGIDALITDE-ADIKLSPEMSSM 120 +R++ E F KYF+E+N GID LI +E I+LS EM M Sbjct: 69 SIRNNIEIFIYVAIAISILILCRVMLSKFAKYFDEINTGIDVLIQNEDKQIELSAEMDVM 128 Query: 121 EQKLVFVKQTLQKRELEVQLSEQNKRDLVMYLAHDIKTPLTSVIGYLSLLHEAPDMPNEQ 180 E KL +K+TL+KRE + +L+EQ K D+VMYLAHDIKTPLTS+IGYLSLL EAPDMP +Q Sbjct: 129 EHKLNTLKRTLEKREQDAKLAEQRKNDVVMYLAHDIKTPLTSIIGYLSLLDEAPDMPVDQ 188 Query: 181 KENYTKITLEKAYHLERLINDFFEVERYNQQTIQLKKQNVDLSYMLIQMPDEFYPSLTPA 240 K Y ITL+KAY LE+LI++FFE+ RYN QTI L K ++DL YML+QM DEFYP L+ Sbjct: 189 KAKYVHITLDKAYRLEQLIDEFFEITRYNLQTITLTKTHIDLYYMLVQMTDEFYPQLSAH 248 Query: 241 GKRMIVNVEDTITVYGDSEKLARVFNNILKNAIAYSDDNSTIEVSAKVQKDM 292 GK+ I++ +TV GD +KLARVFNNILKNA AYS+DNS I+++A + +M Sbjct: 249 GKQAIIHASVDLTVSGDPDKLARVFNNILKNAAAYSEDNSIIDITAGLSGNM 300 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.134 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,534,915,241 Number of extensions: 54955772 Number of successful extensions: 225287 Number of sequences better than 1.0e-05: 6926 Number of HSP's gapped: 230540 Number of HSP's successfully gapped: 6928 Length of query: 318 Length of database: 3,060,696,203 Length adjustment: 135 Effective length of query: 183 Effective length of database: 1,788,859,178 Effective search space: 327361229574 Effective search space used: 327361229574 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 131 (55.1 bits)