BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0249.0004.p (385 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C0Z9Z9.1 C0Z9Z9_BREBN Probable two-component response regulator 388 e-106 B3KAY6.1 B3KAY6_9BACI Response regulator receiver 331 8e-89 C0ZK91.1 C0ZK91_BREBN Putative uncharacterized protein 259 2e-67 B1HY70.1 B1HY70_LYSSC Hypothetical response regulatory protein 229 3e-58 Q65N15.1 Q65N15_BACLD Two-component response regulator 220 2e-55 >C0Z9Z9.1 C0Z9Z9_BREBN Probable two-component response regulator Length = 376 Score = 388 bits (997), Expect = e-106, Method: Compositional matrix adjust. Identities = 194/379 (51%), Positives = 266/379 (70%), Gaps = 3/379 (0%) Query: 6 MKAILIDDEELALKYLEHQLLMLGDFEIAGKYTDPLQGKQMVEETDIDIVFLDIHIPELN 65 MKAILIDDEELAL YLEHQLL +GDFEI GK+TDP+ GK+ +E+ +IDIVFLDI P+LN Sbjct: 1 MKAILIDDEELALNYLEHQLLNIGDFEIVGKFTDPMIGKREIEKKEIDIVFLDIQTPKLN 60 Query: 66 GIELAEMLLEHKPSLQVVFVTAYDEYAIKAFELNALDYVLKPVHPDRLSLTVQRLNSHLK 125 GIELAE LLE KP LQ+VFVTAY+ YAIKAFELNALDYVLKPV RL T++R+ S ++ Sbjct: 61 GIELAEQLLEVKPQLQIVFVTAYERYAIKAFELNALDYVLKPVGKKRLQNTMKRIQSMME 120 Query: 126 AGIAASSTAKPKNWKFLMFDEFRIYEGTQERAPLQWRTAKAQEIFFYLLHHRGKVVSKAT 185 S K +N + +F + +G QE PL+WRTAK Q++F YL+ HRG V+K Sbjct: 121 EH-KTFSPQKSENLQMSLFQQVTFVDGGQE-IPLRWRTAKVQQLFLYLVQHRGTTVNKTA 178 Query: 186 LIELLWADFDLNRAYSQLYTAVYHIRRMLEPFSRDRILLQNTADGYLLKLEGIYLDVDEF 245 +IELLW + + +A QLYTA+YHIR+ L PFS+ + NT++GY +KLE LDVD+F Sbjct: 179 IIELLWPELEPEKANHQLYTAIYHIRKTLAPFSK-YFQISNTSEGYKVKLEQTILDVDQF 237 Query: 246 DRFVKAGMELSKDTVSEYERILKLFKSEYLEGYDYVWAELERQRFQLQWIRLKQNLVHWY 305 +RF ++ + L+ +T+ EYE+ + L K +YL+ ++Y+WAE ERQR QLQW++ +V WY Sbjct: 238 ERFFRSDLSLTAETIDEYEQAMALCKGDYLQEHNYIWAESERQRLQLQWVQTALKMVDWY 297 Query: 306 VKSEDLEQAFKHIEHICSRYPLEEQAQLLYLKICDRMGFHFLVQRQYALLETIMEAELSE 365 +++ ++A IC RYPLEE+A +KI G H V +QY L +++ EL E Sbjct: 298 YANDEWDKAITLCLDICQRYPLEEEAYFFLMKIFADTGRHSSVHKQYDHLTSVLWNELQE 357 Query: 366 KPNQEIVKWYKDWEKKRQK 384 +PN I +WY+ W++K ++ Sbjct: 358 QPNPAITEWYQLWKQKNKE 376 >B3KAY6.1 B3KAY6_9BACI Response regulator receiver Length = 385 Score = 331 bits (848), Expect = 8e-89, Method: Compositional matrix adjust. Identities = 170/377 (45%), Positives = 246/377 (65%), Gaps = 6/377 (1%) Query: 6 MKAILIDDEELALKYLEHQLLMLGDF--EIAGKYTDPLQGKQMVEETDIDIVFLDIHIPE 63 MK IL+DDE LALKYLE QLL L ++ G YT+P +G++ + D+DIVFLDI +PE Sbjct: 1 MKVILVDDEPLALKYLERQLLKLDTMPIDVIGTYTNPFEGRKEILARDVDIVFLDISLPE 60 Query: 64 LNGIELAEMLLEHKPSLQVVFVTAYDEYAIKAFELNALDYVLKPVHPDRLSLTVQRLNSH 123 LNGIELAE LLE KP L +VFVT Y EYA+ AFELNA+DY++KPV DR++ T++RL S Sbjct: 61 LNGIELAEQLLEQKPHLCIVFVTGYHEYAVTAFELNAVDYIVKPVQIDRVAKTMERLRSR 120 Query: 124 LKAGIAASSTAKPKNWKFLMFDEFRIYEGTQER--APLQWRTAKAQEIFFYLLHHRGKVV 181 + A + + MF + I + ++ A L WRT +AQEIF YLL HRG++V Sbjct: 121 I-ASRPEEVLNPNRKIRMTMFRQVMIEQPNEQGQFAMLHWRTTRAQEIFIYLLQHRGQLV 179 Query: 182 SKATLIELLWADFDLNRAYSQLYTAVYHIRRMLEPFSRDRILLQNTADGYLLKLEGIYLD 241 K+ LI++LW +FD+++AY QLYTA+YHIR+ LEP+ R + NT +GY+L +E + LD Sbjct: 180 RKSALIDMLWPEFDMDKAYPQLYTAIYHIRKTLEPYD-TRFQITNTTEGYVLNVEDVQLD 238 Query: 242 VDEFDRFVKAGMELSKDTVSEYERILKLFKSEYLEGYDYVWAELERQRFQLQWIRLKQNL 301 ++E++ + A +S D++ + ++KL+ +YL+ YDY WAE ERQR + W+ + ++ Sbjct: 239 IEEWENWFTANPSVSADSIDGHLEMMKLYTGDYLQEYDYWWAEGERQRLKELWLSVSLSM 298 Query: 302 VHWYVKSEDLEQAFKHIEHICSRYPLEEQAQLLYLKICDRMGFHFLVQRQYALLETIMEA 361 WYV E E+A I +PLEE+A +KI G V RQ++LL +++ Sbjct: 299 AEWYVDQERFEEAVLCFASIQRLHPLEEKAYFSLMKIYGLQGNPAQVHRQFSLLRQVLKD 358 Query: 362 ELSEKPNQEIVKWYKDW 378 E+ E+P+ I KWY +W Sbjct: 359 EMGEEPSPYIKKWYDEW 375 >C0ZK91.1 C0ZK91_BREBN Putative uncharacterized protein Length = 383 Score = 259 bits (663), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 137/382 (35%), Positives = 225/382 (58%), Gaps = 3/382 (0%) Query: 6 MKAILIDDEELALKYLEHQLLM-LGDFEIAGKYTDPLQGKQMVEETDIDIVFLDIHIPEL 64 M+A+L+DDE+L L +L+ L +G ++ G YT+PL+ D+VFLDI++P + Sbjct: 1 MRALLVDDEQLPLMHLQRLLEKDVGGVKVVGAYTNPLEAIDQAISLQPDVVFLDINMPRI 60 Query: 65 NGIELAEMLLEHKPSLQVVFVTAYDEYAIKAFELNALDYVLKPVHPDRLSLTVQRLNSHL 124 +G+E+ E L S ++VFVT YD+YA+ AFEL ALDY++KPV RL T+ RL + Sbjct: 61 SGLEIGERLQGIDNSPEIVFVTGYDKYAVDAFELCALDYIMKPVQLQRLQKTMDRLRERI 120 Query: 125 KAGIAASSTAKPKNWKFLMFDEFRIYEGTQERAPLQWRTAKAQEIFFYLLHHRGKVVSKA 184 K+ A+ + F+ ++ QE ++WRT KA+E+F YLLHHR K++ K Sbjct: 121 KSAKEATPVKEESVVSIQCFNSILFHQPNQEPQEIKWRTNKARELFAYLLHHRNKMIDKD 180 Query: 185 TLIELLWADFDLNRAYSQLYTAVYHIRRMLEPFSRDRILLQ--NTADGYLLKLEGIYLDV 242 +LIELLW D+D ++ +QLYT +Y IR+ L+ + I + N GY L ++ +DV Sbjct: 181 SLIELLWPDYDGSKGVTQLYTTIYLIRQTLKRYGLHTISINKGNLEGGYKLTIDSATIDV 240 Query: 243 DEFDRFVKAGMELSKDTVSEYERILKLFKSEYLEGYDYVWAELERQRFQLQWIRLKQNLV 302 +E++ +K LS + EYE++L + +Y YDY+WAE ER+R + W+ L + + Sbjct: 241 EEWENRLKQIPPLSLANMQEYEQLLAAYTGDYFGDYDYLWAEYERERLRRMWLSLAKTMS 300 Query: 303 HWYVKSEDLEQAFKHIEHICSRYPLEEQAQLLYLKICDRMGFHFLVQRQYALLETIMEAE 362 +Y+ + +A + I + +PLEE + ++ +++ + H V+ QY LL + E E Sbjct: 301 SFYLGHGRVREAINVNQRIQNLHPLEEDSYMILMQLYASLDDHAAVEEQYQLLTSRWENE 360 Query: 363 LSEKPNQEIVKWYKDWEKKRQK 384 L N+ I KWY W+++ ++ Sbjct: 361 LGSAANEHITKWYHIWKQETEQ 382 >B1HY70.1 B1HY70_LYSSC Hypothetical response regulatory protein Length = 384 Score = 229 bits (585), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 130/385 (33%), Positives = 225/385 (58%), Gaps = 16/385 (4%) Query: 6 MKAILIDDEELALKYLEHQL--LMLGDFEIAGKYTDPLQGKQMVEETDIDIVFLDIHIPE 63 M+ +L+DDE L+LK L+ L + EI G+YTD L+ + ++ +VFLDI +P+ Sbjct: 1 MRIVLVDDEYLSLKRLKTLLEESHVPGIEIVGEYTDSLKVIEEIQNLQPSVVFLDIVMPD 60 Query: 64 LNGIELAEMLLEHKPSLQVVFVTAYDEYAIKAFELNALDYVLKPVHPDRLSLTVQRL--- 120 ++G+ L E + E P +++VF T +D+YA+ AF L+A+DY+LKP+ RL T+ RL Sbjct: 61 MDGLALGEKIQELLPDVEIVFTTGFDQYALDAFNLHAVDYLLKPIQITRLEKTLDRLEQI 120 Query: 121 -NSHLKAGIAASSTAKPKNWKFLMFDEFRIYEGTQERAPLQWRTAKAQEIFFYLLHHRGK 179 N H K + ++ + +F ++ L+WRT+KA+E+F YLL+HR + Sbjct: 121 NNKHKKRVVNSTIIS--------LFGGLQVISPDGHTQILKWRTSKAKELFAYLLNHRDE 172 Query: 180 VVSKATLIELLWADFDLNRAYSQLYTAVYHIRRMLEPFSRDRILLQNT--ADGYLLKLEG 237 ++ + T++EL W + D ++A QLYTAVY IR+ L+ + D + + + GY L LE Sbjct: 173 IIYRDTILELFWPESDRDKASKQLYTAVYTIRQTLKNYGLDGVQISSPLLNSGYKLLLEQ 232 Query: 238 IYLDVDEFDRFVKAGMELSKDTVSEYERILKLFKSEYLEGYDYVWAELERQRFQLQWIRL 297 +DV+++ +K+ L ++ V E+E++ +++ +YLE DY+WAE ER+R + W+ Sbjct: 233 TIVDVEQWLSSLKSLPTLEQENVEEHEQVFQMYTGDYLEDCDYLWAESERERLRRLWLHH 292 Query: 298 KQNLVHWYVKSEDLEQAFKHIEHICSRYPLEEQAQLLYLKICDRMGFHFLVQRQYALLET 357 L +Y+K E+ A K E + + + EE+ +K+ D + V+ QY LL+ Sbjct: 293 AHQLSEFYIKIENYSAAIKVQETVQALFAGEEENYFTLMKLYDLLNNVAAVEEQYLLLKK 352 Query: 358 IMEAELSEKPNQEIVKWYKDWEKKR 382 ++ + +P++EI WYK W+K + Sbjct: 353 ALQEHFAVEPSEEIENWYKRWKKTK 377 >Q65N15.1 Q65N15_BACLD Two-component response regulator Length = 358 Score = 220 bits (561), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 120/317 (37%), Positives = 194/317 (61%), Gaps = 14/317 (4%) Query: 6 MKAILIDDEELALKYLEHQLLMLGDFEIAGKYTDPLQGKQMVEETDIDIVFLDIHIPELN 65 MKA+++DDEELAL + ++ L F + DP + + DID VFLDI +P +N Sbjct: 1 MKALIVDDEELALLHFKNMLERTNCFRFIEMFQDPADVLEYPDIRDIDTVFLDIEMPGIN 60 Query: 66 GIELAEMLLEHKPSLQVVFVTAYDEYAIKAFELNALDYVLKPVHPDRLSLTVQRL--NSH 123 GIELAE + ++QVVF+TAY+++AIKAFELNA+DY+LKPV RL T++R+ NS Sbjct: 61 GIELAEAIQSMNENIQVVFITAYNDFAIKAFELNAVDYLLKPVDYVRLVKTIERIRENSL 120 Query: 124 LKAGIAASSTAKPKNWKFLMFDEFRIY---EGTQERAPLQWRTAKAQEIFFYLLHHRGKV 180 LK AS+ ++ F + Y +G + P++WRT+KA+EI+ YLLHH G V Sbjct: 121 LK----ASAVNAGGDYFIQCFGNLQFYKAEKGVKTYIPVKWRTSKAREIYAYLLHHHGHV 176 Query: 181 VSKATLIELLWADFDLNRAYSQLYTAVYHIRRMLE--PFSRDRILLQNTADGYLLKLEGI 238 +SK LI+L W D D+++A +QLY+A+Y IR++++ PF + ++ T GY+L++ G+ Sbjct: 177 ISKDVLIDLFWQDHDVSKASTQLYSAIYQIRKLIDRLPFGQS---IEKTDTGYVLRISGV 233 Query: 239 YLDVDEFDRFVKAGMELSKDTVSEYERILKLFKSEYLEGYDYVWAELERQRFQLQWIRLK 298 +D DE+++ +K + T++ + +L +++ Y + Y+WAE E+ R W+ Sbjct: 234 KVDADEWEKSLKEAPPIHMATINRHMELLLAYENHYFMEHGYLWAEPEKTRLARIWLGKA 293 Query: 299 QNLVHWYVKSEDLEQAF 315 LV + + +D + Sbjct: 294 YELVDFLIHEKDYRRGL 310 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.323 0.139 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,225,161,930 Number of extensions: 90777015 Number of successful extensions: 320694 Number of sequences better than 1.0e-05: 6388 Number of HSP's gapped: 330078 Number of HSP's successfully gapped: 6389 Length of query: 385 Length of database: 3,060,696,203 Length adjustment: 137 Effective length of query: 248 Effective length of database: 1,770,017,148 Effective search space: 438964252704 Effective search space used: 438964252704 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 132 (55.5 bits)