BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0247.0008.p (331 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C0ZJQ9.1 C0ZJQ9_BREBN Putative transcriptional regulator 278 7e-73 B3KA52.1 B3KA52_9BACI Helix-turn-helix type 11 domain protein 262 4e-68 Q8F269.1 Q8F269_LEPIN Transcription regulator 246 2e-63 Q72T75.1 Q72T75_LEPIC Putative transcriptional regulator (DeoR f... 245 5e-63 C1XLN9.1 C1XLN9_MEIRU Predicted transcriptional regulator, COG2378 211 1e-52 >C0ZJQ9.1 C0ZJQ9_BREBN Putative transcriptional regulator Length = 318 Score = 278 bits (710), Expect = 7e-73, Method: Compositional matrix adjust. Identities = 135/312 (43%), Positives = 196/312 (62%), Gaps = 1/312 (0%) Query: 1 MRADRXXXXXXXXQNRGKVTSRELAGTLEVSERTIFRDMEALSASGIPVLAERGREGGWM 60 MRADR QN G++TS++LA LEVSERT+ RDMEALS+SG+PV A RG +GGW Sbjct: 1 MRADRLLAILLLLQNHGRMTSKQLAERLEVSERTVHRDMEALSSSGVPVYALRGADGGWA 60 Query: 61 LTEGYRTSLTGMKPKEIGALQLSADPSILQDLGIHEDYTLATRKLEAAATANTFPSANYF 120 L EGYR++LTGMK E+ +L +++ ++L DLG+HE+Y A KL +A A + Sbjct: 61 LAEGYRSNLTGMKINELQSLLVASPAALLNDLGLHENYEAAFLKLLSALPKTVQQDAIHV 120 Query: 121 NQRIHIDSEGWVPSKESFPFLSELQTALWEDRKVNISYLRNGEVKNRKIGLLGLVAKQGV 180 +HID GW S E+FPFLS +Q A+W RK+ I Y+R R + LGLVAK+ + Sbjct: 121 RHLLHIDGAGWHESTETFPFLSTVQDAVWLSRKLFIRYMREDVAVERIVCPLGLVAKRSI 180 Query: 181 WYVIGEHDGQFRTYRVSRIIACQKIDEAYTRPDDFELTSYWESSKVSFKSALPSYKAKFX 240 WY++ + D RTYR+SR++ +D+ + RP +F+L SYWE S + FKS+LP Y A+ Sbjct: 181 WYLVAKVDEDMRTYRISRLLDAHLLDDGFVRPSEFDLASYWEQSTMDFKSSLPRYPARLL 240 Query: 241 XXXXXXXXXXXERYVTVLSMEDSPGSAWLKVEAEFNTIEAACRVMLSLGPNVIVGEPEEL 300 ERY+ + S + + W++ E EF+T+ +AC ++LS GP++ V EP+EL Sbjct: 241 VKKGTLPAVKQERYIKIASTQAATDD-WMEAEVEFHTLASACSLVLSFGPHIQVLEPQEL 299 Query: 301 RARVYKAALKTV 312 + V + T+ Sbjct: 300 KREVLEQVRATL 311 >B3KA52.1 B3KA52_9BACI Helix-turn-helix type 11 domain protein Length = 317 Score = 262 bits (669), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 137/309 (44%), Positives = 184/309 (59%), Gaps = 1/309 (0%) Query: 1 MRADRXXXXXXXXQNRGKVTSRELAGTLEVSERTIFRDMEALSASGIPVLAERGREGGWM 60 MRADR QN GK +R LA LEVSERTI RDME+LS++GIPV AERG +GGW+ Sbjct: 1 MRADRLLSIMLMLQNGGKKNTRYLAEQLEVSERTIIRDMESLSSAGIPVYAERGSQGGWV 60 Query: 61 LTEGYRTSLTGMKPKEIGALQLSADPSILQDLGIHEDYTLATRKLEAAATANTFPSANYF 120 L E YRT+LTGM P E+ +L +S+ ++ DLGI + + A +KL A++ + A Sbjct: 61 LEESYRTNLTGMTPDELISLLVSSHSPLIGDLGIRKQFDAAYQKLLASSPRSIRQDAEII 120 Query: 121 NQRIHIDSEGWVPSKESFPFLSELQTALWEDRKVNISYLRNGEVKNRKIGLLGLVAKQGV 180 ++IHID GW +ES P+L+ LQ ALW DR ++I Y++ E R+I LGLVAK+ Sbjct: 121 REKIHIDGAGWHSYRESHPYLTVLQEALWLDRIMDIQYMKGEERVERRIHPLGLVAKRST 180 Query: 181 WYVIGEHDGQFRTYRVSRIIACQKIDEAYTRPDDFELTSYWESSKVSFKSALPSYKAKFX 240 WYV+ E G+ RTYRVSRI+ ++ + RP F L YWE S F LP Y A+ Sbjct: 181 WYVVAESQGELRTYRVSRIVDAVMSEDTFQRPAGFNLAEYWEESLARFMQNLPQYPAQVR 240 Query: 241 XXXXXXXXXXXERYVTVLSME-DSPGSAWLKVEAEFNTIEAACRVMLSLGPNVIVGEPEE 299 ERYV +L + D+ W+ + EFNT+E+A +LS G + V P+E Sbjct: 241 MTVHLIKRFERERYVKILRCDMDNQHDGWITADLEFNTLESASAFLLSCGAEIEVMAPQE 300 Query: 300 LRARVYKAA 308 LR V AA Sbjct: 301 LREHVSMAA 309 >Q8F269.1 Q8F269_LEPIN Transcription regulator Length = 317 Score = 246 bits (628), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 130/304 (42%), Positives = 184/304 (60%), Gaps = 2/304 (0%) Query: 1 MRADRXXXXXXXXQNRGKVTSRELAGTLEVSERTIFRDMEALSASGIPVLAERGREGGWM 60 MRADR Q +G+++SR+LA LEVSERTI RDMEALSASGIPV AERG +GGW Sbjct: 1 MRADRLLSILLQLQAKGRISSRDLAKKLEVSERTIHRDMEALSASGIPVFAERGSKGGWE 60 Query: 61 LTEGYRTSLTGMKPKEIGALQLSADPSILQDLGIHEDYTLATRKLEAAATANTFPSANYF 120 L+EGYRT+LTGMK +EI ++ L++ I DLG +D A K A+ A Sbjct: 61 LSEGYRTNLTGMKKEEIFSMILTSSTRIASDLGRKKDLDSALMKFMASLPPAYQKEAEMV 120 Query: 121 NQRIHIDSEGWVPSKESFPFLSELQTALWEDRKVNISYLRNGEVKNRKIGLLGLVAKQGV 180 QRI++D GW S+E PFLS +Q A+W+ +K+ + Y + E K R + LGLVAK + Sbjct: 121 RQRIYVDGAGWSCSEEELPFLSLIQEAVWQGKKIVLRYKTDEESKKRNVSPLGLVAKGKI 180 Query: 181 WYVIGEHDGQFRTYRVSRIIACQKIDEAYTRPDDFELTSYWESSKVSFKSALPSYKAKFX 240 WY++ +++ +FRT+RVSRI+ K+ +++ RP F+L YW+ S +F S +PSY +F Sbjct: 181 WYLVAKYEKEFRTFRVSRIVEA-KLGDSFERPKRFDLEKYWKDSTQNFLSKIPSYPVRFK 239 Query: 241 XXXXXXXXXXXERYVTVLSMEDSPGSAWLKVEAEFNTIEAACRVMLSLGPNVIVGEPEEL 300 Y+ +L W++V A+ T E A +L LG +V++ EPEEL Sbjct: 240 IHVSKIDFLKNILYIRILKYSKITKD-WIEVTADLETREWALHHILGLGDSVVLWEPEEL 298 Query: 301 RARV 304 R + Sbjct: 299 RESI 302 >Q72T75.1 Q72T75_LEPIC Putative transcriptional regulator (DeoR family) Length = 317 Score = 245 bits (625), Expect = 5e-63, Method: Compositional matrix adjust. Identities = 130/304 (42%), Positives = 184/304 (60%), Gaps = 2/304 (0%) Query: 1 MRADRXXXXXXXXQNRGKVTSRELAGTLEVSERTIFRDMEALSASGIPVLAERGREGGWM 60 MRADR Q +G+++SR+LA LEVSERTI RDMEALSASGIPV AERG +GGW Sbjct: 1 MRADRLLSILLQLQAKGRISSRDLAKKLEVSERTIHRDMEALSASGIPVYAERGSKGGWE 60 Query: 61 LTEGYRTSLTGMKPKEIGALQLSADPSILQDLGIHEDYTLATRKLEAAATANTFPSANYF 120 L+EGYRT+LTGMK +EI ++ L++ I DLG +D A K A+ A Sbjct: 61 LSEGYRTNLTGMKKEEIFSMILTSSTRIASDLGRKKDLDSALMKFMASLPPAYQKEAEMV 120 Query: 121 NQRIHIDSEGWVPSKESFPFLSELQTALWEDRKVNISYLRNGEVKNRKIGLLGLVAKQGV 180 QRI++D GW S+E PFLS +Q A+W+ +K+ + Y + E K R + LGLVAK + Sbjct: 121 RQRIYVDGAGWSCSEEELPFLSLIQEAVWQGKKIVLRYKTDEESKKRNVSPLGLVAKGKI 180 Query: 181 WYVIGEHDGQFRTYRVSRIIACQKIDEAYTRPDDFELTSYWESSKVSFKSALPSYKAKFX 240 WY++ +++ +FRT+RVSRI+ K+ +++ RP F+L YW+ S +F S +PSY +F Sbjct: 181 WYLVAKYEKEFRTFRVSRIVEA-KLGDSFERPKRFDLEKYWKDSTQNFLSKIPSYPVRFK 239 Query: 241 XXXXXXXXXXXERYVTVLSMEDSPGSAWLKVEAEFNTIEAACRVMLSLGPNVIVGEPEEL 300 Y+ +L W++V A+ T E A +L LG +V++ EPEEL Sbjct: 240 IHVSKIDFLKNILYIRILKY-SKINKDWIEVIADLETREWALHHILGLGDSVVLWEPEEL 298 Query: 301 RARV 304 R + Sbjct: 299 RESI 302 >C1XLN9.1 C1XLN9_MEIRU Predicted transcriptional regulator, COG2378 Length = 321 Score = 211 bits (536), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 125/315 (39%), Positives = 169/315 (53%), Gaps = 4/315 (1%) Query: 1 MRADRXXXXXXXXQNRGKVTSRELAGTLEVSERTIFRDMEALSASGIPVLAERGREGGWM 60 MRADR Q RG+ T+ ELA LEVS RTI RDMEAL+ASG+PV AERG +GGW Sbjct: 1 MRADRLVSILLLLQTRGRATTAELAKRLEVSPRTIHRDMEALTASGVPVYAERGSKGGWR 60 Query: 61 LTEGYRTSLTGMKPKEIGALQLSADPSILQDLGIHEDYTLATRKLEAAATANTFPSANYF 120 L E YRT+LTG+ EI AL +L+DLG+ + A K+ AA A A Y Sbjct: 61 LLEEYRTNLTGLSQPEIMALFALKPTQLLRDLGLGKAGENALIKMLAALPAAQRRGAEYA 120 Query: 121 NQRIHIDSEGWVPSKESFPFLSELQTALWEDRKVNISY-LRNGEVKNRKIGLLGLVAKQG 179 QRI +D + + +E P L LQ A+W+DRK+ + Y G+ R + LGLV K Sbjct: 121 RQRILVDIQRY---QEKVPLLPVLQEAVWQDRKLRLVYEPMEGQPAERTVDPLGLVVKGS 177 Query: 180 VWYVIGEHDGQFRTYRVSRIIACQKIDEAYTRPDDFELTSYWESSKVSFKSALPSYKAKF 239 VWY++ G+ R+YRVSRI+ +DE RP DF+L +YW ++ F++ +PSY+ Sbjct: 178 VWYLVASRQGELRSYRVSRILEASVLDEPSQRPADFDLEAYWHKARADFRAKIPSYRIWV 237 Query: 240 XXXXXXXXXXXXERYVTVLSMEDSPGSAWLKVEAEFNTIEAACRVMLSLGPNVIVGEPEE 299 + L G +WLK + F E A +L+ G V EP E Sbjct: 238 RVQEKVLARSNPASHWGQLEHCKPAGDSWLKAQIRFEYPEQALGWVLAAGAGVEALEPLE 297 Query: 300 LRARVYKAALKTVLL 314 R +V +A K + L Sbjct: 298 FRKQVLEALSKALAL 312 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.316 0.132 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,787,706,468 Number of extensions: 68625554 Number of successful extensions: 150703 Number of sequences better than 1.0e-05: 493 Number of HSP's gapped: 150384 Number of HSP's successfully gapped: 494 Length of query: 331 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 195 Effective length of database: 1,779,438,163 Effective search space: 346990441785 Effective search space used: 346990441785 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 131 (55.1 bits)