BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0231.0085.p (707 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A4J477.1 A4J477_DESRM Diguanylate cyclase/phosphodiesterase with... 414 e-113 C0ZBG1.1 C0ZBG1_BREBN Probable signaling protein YkoW 405 e-111 B3PCE8.1 B3PCE8_CELJU Sensory box/GGDEF family protein 393 e-107 B9LZ98.1 B9LZ98_GEOSF Diguanylate cyclase/phosphodiesterase with... 392 e-106 B3EBJ5.1 B3EBJ5_GEOLS Diguanylate cyclase/phosphodiesterase with... 389 e-106 >A4J477.1 A4J477_DESRM Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(S) Length = 947 Score = 414 bits (1064), Expect = e-113, Method: Compositional matrix adjust. Identities = 200/431 (46%), Positives = 296/431 (68%), Gaps = 6/431 (1%) Query: 272 INYLAYHDDLTGLPNRRRLMQRVEEMLLQSERDKSRGFTALVIMNINHFKNINDSLGHYA 331 + YLAYHD LT LPNR R+ L Q+ R+K++ A++ ++++HFK +ND+LGH Sbjct: 512 LRYLAYHDSLTELPNRTLFNDRLSMALNQAHRNKNK--LAVMFLDLDHFKKVNDTLGHDI 569 Query: 332 GDLLLQLVAKRIGNEAKANEELYSMGADEFAFLMTDRTGVENCLIRAGELLRLFDTPVQL 391 GD LL+ +A+R + + + +G DEF L+ + T EN I A +++ P + Sbjct: 570 GDQLLKGIAQRFSKLLRKGDTIARIGGDEFTILLHNITRAENASIVADKIIDTLANPWII 629 Query: 392 ESGEYHISLSLGMSIYPGDGDTAEQLIQNADTAVHNAKDQGVE-IRRYIPAMQMKAKERL 450 + E+HI+ S+G+++YP DG AE L++NAD A++ AK+ G + Y P M + R Sbjct: 630 GNHEFHITTSIGIALYPDDGTDAESLLKNADAAMYQAKEMGRNNYQFYTPTMNAQTLRRF 689 Query: 451 KLENDLRRALERDEFYLVYQPQVQLETEEIVGMEALLRWNHPKRGLVSPVDFIPIAEESG 510 +LEN+LRRAL+R EF + YQPQV++ T +IVG+EAL+RW HP+RG++SP +FIP+AEE+G Sbjct: 690 ELENNLRRALDRKEFVIYYQPQVEIHTGKIVGVEALIRWQHPQRGMISPAEFIPMAEETG 749 Query: 511 LIVPIGEWVLKTACLQNKMWQNAGYRPICVSINLSMRQFLQPNLAGKIDVILQDIGLDPC 570 LI+PIGEW+L+ AC QNK WQ+ G+ P+ V++NLS RQFLQP+L I +L+D GL P Sbjct: 750 LIIPIGEWILRRACAQNKAWQDRGFSPMRVTVNLSARQFLQPHLPQYISNVLEDTGLGPQ 809 Query: 571 YVDLEITESMTLDKETAFDQ--LNRLKRLGVFISIDDFGTGYSSLHYLKNMPIDRLKIDR 628 +++LEITES+ + K+ AF + L L+++G+ ++IDDFGTGYSSL+YLK +PID LKIDR Sbjct: 810 WLELEITESLAM-KDVAFTEKTLIELRKMGITLAIDDFGTGYSSLNYLKRLPIDILKIDR 868 Query: 629 SFVSEVLEDSNNAAIVSTITSMAHHLKLKVTAEGVENXXXXXXXXXXXCHEGQGYLFSKP 688 SF+ ++ +S++ AI+S I ++ H+LK+KV AEGVE C QGYLF+KP Sbjct: 869 SFIHDLNTESDDVAIISAIITLGHNLKMKVVAEGVETKEQLMFLRQQQCDLMQGYLFTKP 928 Query: 689 IKAAEFETFFL 699 + E E +L Sbjct: 929 LPVRELEQKYL 939 >C0ZBG1.1 C0ZBG1_BREBN Probable signaling protein YkoW Length = 805 Score = 405 bits (1041), Expect = e-111, Method: Compositional matrix adjust. Identities = 202/437 (46%), Positives = 292/437 (66%), Gaps = 5/437 (1%) Query: 270 ARINYLAYHDDLTGLPNRRRLMQRVEEMLLQSERDKSRGFTALVIMNINHFKNINDSLGH 329 A+INYLA+HD LTGLPNRR + Q+++++++++++ + + ++ ++++HFK +NDSLGH Sbjct: 372 AKINYLAFHDSLTGLPNRRFVEQQLDQVIMEAQKTDQQVY--VLFLDLDHFKLVNDSLGH 429 Query: 330 YAGDLLLQLVAKRIGNEAKANEELYSMGADEFAFLMTDRTGVENCLIRAGELLRLFDTPV 389 GDLLLQ + R+ +Y +G DEF ++TD T E + A E+ + Sbjct: 430 DFGDLLLQEASLRLRECVGKKGTVYRLGGDEFMVILTDVTEREVSSM-ANEINETIEQAF 488 Query: 390 QLESGEYHISLSLGMSIYPGDGDTAEQLIQNADTAVHNAKDQGV-EIRRYIPAMQMKAKE 448 + E +I+ S+G+S YP DG L++NAD A++ AKD+G Y+P ++ + Sbjct: 489 FIHGHELYITTSIGISRYPEDGQDRSVLMRNADAAMYAAKDKGKNSFHLYVPNLEQAVND 548 Query: 449 RLKLENDLRRALERDEFYLVYQPQVQLETEEIVGMEALLRWNHPKRGLVSPVDFIPIAEE 508 ++ ++N+L RAL R EF L YQPQV ++ IVG+EAL+RW+HP+RGL+ P FI +AEE Sbjct: 549 KMNIQNELNRALARQEFLLHYQPQVSAKSGAIVGVEALIRWDHPERGLLLPDQFISVAEE 608 Query: 509 SGLIVPIGEWVLKTACLQNKMWQNAGYRPICVSINLSMRQFLQPNLAGKIDVILQDIGLD 568 +GLIVPIGEWVL+TAC QNK WQ+ G +P+ V++NLS RQFL+ + I IL L Sbjct: 609 TGLIVPIGEWVLRTACKQNKQWQDQGLKPLRVAVNLSARQFLKQDFTQMIAEILHQTRLA 668 Query: 569 PCYVDLEITESMTLDKETAFDQLNRLKRLGVFISIDDFGTGYSSLHYLKNMPIDRLKIDR 628 P Y++LEITES +D A L LK+LGV ++IDDFGTGYSSL+YLK P++RLKIDR Sbjct: 669 PEYLELEITESSMIDVHRATQALKELKQLGVHVAIDDFGTGYSSLYYLKEFPLNRLKIDR 728 Query: 629 SFVSEVLEDSNNAAIVSTITSMAHHLKLKVTAEGVENXXXXXXXXXXXCHEGQGYLFSKP 688 SFV +++E +N AIVSTI SMAHHL++ V AEGVE C E QGYLFS+P Sbjct: 729 SFVRDMIEQPSNQAIVSTIISMAHHLQMHVIAEGVETKEELAFLQEHLCEEVQGYLFSRP 788 Query: 689 IKAAEFETFFLKPSLGM 705 + + + F+L+ G+ Sbjct: 789 LPSEDV-AFYLQAQKGV 804 >B3PCE8.1 B3PCE8_CELJU Sensory box/GGDEF family protein Length = 772 Score = 393 bits (1010), Expect = e-107, Method: Compositional matrix adjust. Identities = 192/431 (44%), Positives = 286/431 (66%), Gaps = 4/431 (0%) Query: 270 ARINYLAYHDDLTGLPNRRRLMQRVEEMLLQSERDKSRGFTALVIMNINHFKNINDSLGH 329 +R+NY+A+HD LT LPNR R+ L ++ R SR AL++++I+ FK +NDSLGH Sbjct: 322 SRLNYMAFHDALTSLPNRSLFYDRIYHGLARARRSNSR--VALMLLDIDRFKIVNDSLGH 379 Query: 330 YAGDLLLQLVAKRIGNEAKANEELYSMGADEFAFLMTDRTGVENCLIRAGELLRLFDTPV 389 AGD+LL+ +A R+ + + + +G DEF ++ V++ + A +LL P+ Sbjct: 380 DAGDILLKAIAMRLTEGVRDMDTVARLGGDEFVVVLEGIHDVDDVIFVANKLLATLSRPL 439 Query: 390 QLESGEYHISLSLGMSIYPGDGDTAEQLIQNADTAVHNAKDQGVE-IRRYIPAMQMKAKE 448 + ++S+G+SI+P DG ++L++NAD A++ AK+ G + Y M A Sbjct: 440 DISGHSISATVSIGVSIFPEDGADTDELLKNADIAMYKAKEAGKNNCQFYTKGMNATAVN 499 Query: 449 RLKLENDLRRALERDEFYLVYQPQVQLETEEIVGMEALLRWNHPKRGLVSPVDFIPIAEE 508 L LENDLRRA+E+++ L YQPQ+ L+T ++ G+EAL+RW HP+RGLVSP FIP+AEE Sbjct: 500 YLLLENDLRRAIEQNQLALYYQPQIDLKTGDMTGVEALVRWQHPERGLVSPAHFIPLAEE 559 Query: 509 SGLIVPIGEWVLKTACLQNKMWQNAGYRPICVSINLSMRQFLQPNLAGKIDVILQDIGLD 568 +GLIVPIGEWVL+ AC Q K+W + G V++NLS RQF Q N GK++ ILQ+ GL+ Sbjct: 560 TGLIVPIGEWVLREACKQKKIWLDTGKNVGKVAVNLSPRQFRQKNFPGKVEAILQETGLE 619 Query: 569 PCYVDLEITESMTLDKE-TAFDQLNRLKRLGVFISIDDFGTGYSSLHYLKNMPIDRLKID 627 Y++LEITES ++ +QLN+L ++G F++IDDFGTGYSSL YL+ PI +LKID Sbjct: 620 AKYLELEITESCAMEHAGETINQLNQLNQMGTFLAIDDFGTGYSSLAYLQRFPIQKLKID 679 Query: 628 RSFVSEVLEDSNNAAIVSTITSMAHHLKLKVTAEGVENXXXXXXXXXXXCHEGQGYLFSK 687 RSF+ ++ +D+N+AAI TI +AH+++L+V AEGVE C + QG+L++K Sbjct: 680 RSFIHDIHDDANDAAIAKTIIGLAHNMQLRVVAEGVETESQAEWLRAKGCDQVQGFLYAK 739 Query: 688 PIKAAEFETFF 698 P+ A + E+ F Sbjct: 740 PMTAKQLESHF 750 >B9LZ98.1 B9LZ98_GEOSF Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) Length = 912 Score = 392 bits (1006), Expect = e-106, Method: Compositional matrix adjust. Identities = 200/429 (46%), Positives = 283/429 (65%), Gaps = 4/429 (0%) Query: 272 INYLAYHDDLTGLPNRRRLMQRVEEMLLQSERDKSRGFTALVIMNINHFKNINDSLGHYA 331 I LAY+D LTGLPNR L R+ + ++Q+ RD + A++ ++++ FK+IND+LGH A Sbjct: 478 IQQLAYYDTLTGLPNRSLLQDRLGQGIVQAVRDNRK--VAIMFLDLDRFKSINDTLGHVA 535 Query: 332 GDLLLQLVAKRIGNEAKANEELYSMGADEFAFLMTDRTGVENCLIRAGELLRLFDTPVQL 391 GD LL VA+R+ + + + +G DEF +++ E+ A ++L P+ L Sbjct: 536 GDSLLATVAERLTECVRETDTVARIGGDEFVIIISAIEHAEDLNKIAEKILAAISKPLVL 595 Query: 392 ESGEYHISLSLGMSIYPGDGDTAEQLIQNADTAVHNAKDQGVEIRRYIP-AMQMKAKERL 450 E I+ S+G++IYP DG + L++NAD A++ AKDQG +Y M ++A E L Sbjct: 596 NDQEIFITASIGIAIYPEDGTDVQGLLKNADLAMYKAKDQGKNAFQYFSREMNVQALEHL 655 Query: 451 KLENDLRRALERDEFYLVYQPQVQLETEEIVGMEALLRWNHPKRGLVSPVDFIPIAEESG 510 LEN LRRALER+EF + YQPQ+ L++ +VGMEAL+RW HP GL+ P FIP+AEE+G Sbjct: 656 ILENSLRRALERNEFVIFYQPQMDLKSGRLVGMEALIRWQHPDLGLLPPSRFIPMAEETG 715 Query: 511 LIVPIGEWVLKTACLQNKMWQNAGYRPICVSINLSMRQFLQPNLAGKIDVILQDIGLDPC 570 LI+PIGEW L+TAC +N+ W +AG+ P+ V++NL QF Q I+ +L+ GL P Sbjct: 716 LILPIGEWALQTACAKNRAWMDAGFMPLRVAVNLCGIQFRQKKFIELIEAVLKKTGLAPS 775 Query: 571 YVDLEITESMTLDK-ETAFDQLNRLKRLGVFISIDDFGTGYSSLHYLKNMPIDRLKIDRS 629 ++LE+TESM + K E + L++LK +GV ++IDDFGTGYSSL YLKN PI+R+KIDRS Sbjct: 776 QLELELTESMLMSKAEESTTVLHKLKEMGVSLAIDDFGTGYSSLSYLKNFPINRVKIDRS 835 Query: 630 FVSEVLEDSNNAAIVSTITSMAHHLKLKVTAEGVENXXXXXXXXXXXCHEGQGYLFSKPI 689 F+ +V + ++ AIVS I +MAH+L LKVTAEGVEN C+E QGYL S P+ Sbjct: 836 FIRDVPNNPDDTAIVSAIIAMAHNLNLKVTAEGVENHSQLEFLSTRNCNEIQGYLLSSPL 895 Query: 690 KAAEFETFF 698 AEF F Sbjct: 896 PEAEFTRFL 904 >B3EBJ5.1 B3EBJ5_GEOLS Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) Length = 965 Score = 389 bits (999), Expect = e-106, Method: Compositional matrix adjust. Identities = 200/431 (46%), Positives = 283/431 (65%), Gaps = 4/431 (0%) Query: 272 INYLAYHDDLTGLPNRRRLMQRVEEMLLQSERDKSRGFTALVIMNINHFKNINDSLGHYA 331 I LAYHD +TGLPNR L R++ + ++ERD S+G A++ ++++ FK INDSLGH Sbjct: 523 IEQLAYHDPVTGLPNRTLLHDRLQLAINRAERD-SQG-VAILFLDLDRFKAINDSLGHAM 580 Query: 332 GDLLLQLVAKRIGNEAKANEELYSMGADEFAFLMTDRTGVENCLIRAGELLRLFDTPVQL 391 GD LL+LV R+ + ++++ + +G DEF L++ ++L P Q+ Sbjct: 581 GDQLLRLVGNRLLDCVRSSDTVARLGGDEFVVLISALDNDHAVGSVVMKILEQLCEPYQI 640 Query: 392 ESGEYHISLSLGMSIYPGDGDTAEQLIQNADTAVHNAKDQGVEIRRYI-PAMQMKAKERL 450 + E + S S+G+S++P DG AE+L++NAD A++ AK+ G + P + M+A ERL Sbjct: 641 DDHEVYTSSSIGISLFPRDGRDAEELLKNADMAMYQAKEAGRNTCHFFSPELNMRATERL 700 Query: 451 KLENDLRRALERDEFYLVYQPQVQLETEEIVGMEALLRWNHPKRGLVSPVDFIPIAEESG 510 LE+ +RRALER+EF+LVYQPQ++L + I G+EALLRW HP G+V P +FIPIAEE+G Sbjct: 701 LLESTMRRALEREEFFLVYQPQMELRSGHIAGIEALLRWRHPDLGVVPPNNFIPIAEETG 760 Query: 511 LIVPIGEWVLKTACLQNKMWQNAGYRPICVSINLSMRQFLQPNLAGKIDVILQDIGLDPC 570 LIVP+GEWVL AC Q WQ G P+ +++N+S RQF Q NL +I+ IL + GLDP Sbjct: 761 LIVPLGEWVLAEACRQAVRWQQEGQPPLRMAVNVSARQFRQRNLGLRIEKILMETGLDPA 820 Query: 571 YVDLEITESMTLDK-ETAFDQLNRLKRLGVFISIDDFGTGYSSLHYLKNMPIDRLKIDRS 629 ++LE+TES ++ E A L +LK++G+ +SIDDFGTGYSSL +LK+ PIDRLKIDRS Sbjct: 821 LLELELTESAVMENPEEAILTLRQLKKMGITLSIDDFGTGYSSLSHLKHFPIDRLKIDRS 880 Query: 630 FVSEVLEDSNNAAIVSTITSMAHHLKLKVTAEGVENXXXXXXXXXXXCHEGQGYLFSKPI 689 FV V D N+A I I ++AH +KL V AEG+E+ C QGY S+P+ Sbjct: 881 FVKHVTRDHNDATIAEAIIALAHSMKLTVVAEGIEHSEQMEFMHQRHCDTMQGYYLSRPV 940 Query: 690 KAAEFETFFLK 700 A EF TF + Sbjct: 941 TAEEFGTFLKR 951 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.323 0.139 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,684,930,352 Number of extensions: 144659757 Number of successful extensions: 360839 Number of sequences better than 1.0e-05: 15562 Number of HSP's gapped: 331004 Number of HSP's successfully gapped: 15631 Length of query: 707 Length of database: 3,060,696,203 Length adjustment: 143 Effective length of query: 564 Effective length of database: 1,713,491,058 Effective search space: 966408956712 Effective search space used: 966408956712 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 135 (56.6 bits)