BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0231.0079.p (514 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KB30.1 B3KB30_9BACI Leucyl aminopeptidase EC=3.4.11.1 505 e-141 B1DIR4.1 B1DIR4_9BACL Leucyl aminopeptidase EC=3.4.11.1 393 e-107 B4BSE6.1 B4BSE6_9BACI Leucyl aminopeptidase EC=3.4.11.1 366 3e-99 A4ISE0.1 A4ISE0_GEOTN Thermostable leucine aminopeptidase 362 4e-98 A6TWW9.1 AMPA_ALKMQ Probable cytosol aminopeptidase EC=3.4.11.1 352 4e-95 >B3KB30.1 B3KB30_9BACI Leucyl aminopeptidase EC=3.4.11.1 Length = 505 Score = 505 bits (1301), Expect = e-141, Method: Compositional matrix adjust. Identities = 259/500 (51%), Positives = 344/500 (68%), Gaps = 8/500 (1%) Query: 6 IKWS--SGIQAKTLQGDALCLMIAENDMESSEAG---EWTEQISRVSQAGLFGAKLNQIY 60 +KW+ S + A +Q DA+ + + + ++ E G W + ++++ LF N+ + Sbjct: 1 MKWTFESNLTAGQVQADAIIVPVTKK--QAKEGGISPAWDPLLKQLAENRLFDGTANRSF 58 Query: 61 VLPLEGQPGLPVLILAGCGNGLEGTDEXXXXXXXXXXXXXXXXXXXXIIQVPDNLSKLTA 120 V P G +LI G G+ +++ IQ+P + TA Sbjct: 59 VWPESISSGSRLLIWVGRPEGILTSEQLRLVAAQAAKAAVKSGIRSAAIQIPHTMVSFTA 118 Query: 121 VR-PHEAGQALTEGLILGAYRRTHYKREQPVYAGLESAVFHLDRQAEAAESLEWSQGIRQ 179 + P +A QALTEG ILG+YR+ HYKR+ + LE +++++ AEA W +G+ Sbjct: 119 EQTPRDAAQALTEGFILGSYRKPHYKRDASEHTDLEEILYYIEGNAEAEYEAAWKEGMSL 178 Query: 180 GQAFGEATNLARXXXXXXXXXXXXSALAMAAIEVAERHGFPAEVLDEQEIAQKGMGGLLA 239 GQA GEAT LAR LA A+++A+R+GF A+VLDE+ + +KGMGGLLA Sbjct: 179 GQAIGEATCLARDLTNLPGNKLLPEDLAQKALQLAKRYGFEAQVLDEEAMVEKGMGGLLA 238 Query: 240 VGKGSVHPPRMIVIRYQGTSQWENVTAIVGKGITFDSGGISLKRAPGMEDMISDMGGAAA 299 VGKGS+HPPRMI IRYQG W++V ++GKGITFD+GG+SLKRA GMEDMISDMGGAA Sbjct: 239 VGKGSIHPPRMITIRYQGRETWDDVIGLIGKGITFDTGGVSLKRAVGMEDMISDMGGAAT 298 Query: 300 VLGVMEALGTLRPRINIVMLIPSAENMPAANAFKPGDIVTTLSGRTIEILNTDAEGRVVL 359 VLGVMEALG +RP+ N+VM+IPSAEN+ + AFKPGDIVTTLSGRT+E+LNTDAEGR+VL Sbjct: 299 VLGVMEALGRIRPKANVVMVIPSAENVMSGGAFKPGDIVTTLSGRTVEVLNTDAEGRIVL 358 Query: 360 ADALTYSLEWGAERIIDVATLTGAVLSVLGDIATGAVTNNEVMMEALQTASIRAGEKIWR 419 AD +T++ + G+ R+IDVATLTGAV+S LGDIATGAVTN+E ++ L +S RAGEKIW Sbjct: 359 ADGVTHAKQLGSSRLIDVATLTGAVVSALGDIATGAVTNDETFLQELIASSRRAGEKIWP 418 Query: 420 LPVFPEFREMLSSEVADIRNAAGRYGGASTAGLFIGEFAEGRPWVHLDIAGTAFLSKERG 479 LP +PEF + L SEVAD+RN GR GG T GLF+G FA+G PWVH DIAGTA+LSKERG Sbjct: 419 LPSYPEFWDKLKSEVADLRNQTGREGGTITGGLFVGTFADGLPWVHFDIAGTAYLSKERG 478 Query: 480 VNPKGATGVMVRTLLQYLLH 499 V+P+GATGV+VRT+ ++L Sbjct: 479 VDPRGATGVLVRTISDWILR 498 >B1DIR4.1 B1DIR4_9BACL Leucyl aminopeptidase EC=3.4.11.1 Length = 505 Score = 393 bits (1009), Expect = e-107, Method: Compositional matrix adjust. Identities = 218/487 (44%), Positives = 296/487 (60%), Gaps = 12/487 (2%) Query: 20 DALCLMIAENDMESSEAGEWT-----EQISRVSQAGLFGAKLNQIYVLPLEGQPGLPVLI 74 DA+ +I+ ++++ EW E + + GLF A+ Q L G +I Sbjct: 17 DAIVRLISSAELKAGSMAEWVQPQIDEAVRGLYAKGLFKAEPEQTETLSTLGLHSASHVI 76 Query: 75 LAGCGNGLEGTDEXXXXXXXXXXXXXXXXXXXXIIQVPDNLSKLTAVRPHEAGQALTEGL 134 AG + G I++P+ + +A QAL EGL Sbjct: 77 FAGYDDK-AGVYGLRLAAAAAANALKRIKAQTAQIRLPETIISSADYTLQQAAQALVEGL 135 Query: 135 ILGAYRRTHYKREQPVYAGLESAVF----HLDRQAEAAESLEWSQGIRQGQAFGEATNLA 190 L + R R+ L F + A+ AE+ W++G+ GQ + E +A Sbjct: 136 TLAVHDRLPELRQAKQRYTLSHVSFVPAAGVAVPADIAET--WNEGMMVGQLYAEGVKVA 193 Query: 191 RXXXXXXXXXXXXSALAMAAIEVAERHGFPAEVLDEQEIAQKGMGGLLAVGKGSVHPPRM 250 R +LA A E+A EVLDE ++GMGGLLAVG+GSVH PRM Sbjct: 194 RDLTNLPGNQLVPESLAAHAEELAREWDLDIEVLDEWAAIEQGMGGLLAVGQGSVHAPRM 253 Query: 251 IVIRYQGTSQWENVTAIVGKGITFDSGGISLKRAPGMEDMISDMGGAAAVLGVMEALGTL 310 IVI Y+G E ++GKGITFD+GGISLK+ PGME+MISDMGGAAAVLG M +G L Sbjct: 254 IVIHYKGAPDKEEAWGLIGKGITFDTGGISLKKGPGMEEMISDMGGAAAVLGAMRIIGEL 313 Query: 311 RPRINIVMLIPSAENMPAANAFKPGDIVTTLSGRTIEILNTDAEGRVVLADALTYSLEWG 370 +P +N++ +IP+AENMP+A AFKPGD++ ++G T+EI+NTDAEGR+VL D LT ++ G Sbjct: 314 KPEVNVIAVIPTAENMPSAQAFKPGDVIKMMNGLTVEIVNTDAEGRLVLGDGLTTAIRRG 373 Query: 371 AERIIDVATLTGAVLSVLGDIATGAVTNNEVMMEALQTASIRAGEKIWRLPVFPEFREML 430 A +++DVATLTGAV+ LG ATGA+TNNE +M+ + A+ R+GE+IW+LP FPE++ L Sbjct: 374 ATQLVDVATLTGAVMVALGTEATGAITNNEPLMQQVFEAAGRSGERIWQLPAFPEYKRQL 433 Query: 431 SSEVADIRNAAGRYGGASTAGLFIGEFAEGRPWVHLDIAGTAFLSKERGVNPKGATGVMV 490 S+ AD++N+ GRY GA+T GLFIG FAE PWVHLDIAGTAFL K RG+ PKGATGVMV Sbjct: 434 RSDAADLKNSGGRYAGATTGGLFIGAFAEDLPWVHLDIAGTAFLDKSRGLEPKGATGVMV 493 Query: 491 RTLLQYL 497 RTL++ + Sbjct: 494 RTLVELV 500 >B4BSE6.1 B4BSE6_9BACI Leucyl aminopeptidase EC=3.4.11.1 Length = 506 Score = 366 bits (940), Expect = 3e-99, Method: Compositional matrix adjust. Identities = 221/504 (43%), Positives = 295/504 (58%), Gaps = 19/504 (3%) Query: 2 IFIDIKWSSGIQAKTLQGDALCLMIAE-NDMESSEAGEWTE----QISRVSQAGLFGAKL 56 +F WSS + +AL + + E D S AGE+ Q+S + + G AK Sbjct: 10 MFTVKPWSSA----EVVHEALAIGLFEGKDSWSGLAGEYDSRLGGQLSNLRKEGDISAKR 65 Query: 57 NQIYVLPLEGQPGLPVLILAGCGNGLEGTDEXXXXXXXXXXXXXXXXXXXXIIQVPDNLS 116 +I + G+ L G G E T E D + Sbjct: 66 GRIATIHTMLPTGVKRLYFVGFGKKEELTFERLREVFGKLFRTWKQAKRTEAAIALDTFT 125 Query: 117 KLTAVRPHEAGQALTEGLILGAYRRTHYK--REQPVYAGLESAVFHLDRQAEAAESLEWS 174 T V P+EA AL E L Y YK + +P YA LES + AA++ E Sbjct: 126 TET-VDPNEAAHALAEAYYLATYEFPGYKQKKSEPDYA-LESLTVYT-----AADAAEIE 178 Query: 175 QGIRQGQAFGEATNLARXXXXXXXXXXXXSALAMAAIEVAERHGFPAEVLDEQEIAQKGM 234 + G +G+ATN AR S LA A+E+A+R+ F E+L+++E+ + GM Sbjct: 179 ASLFVGSVYGKATNSARTLVNTPGNLLTASDLADYAVELAKRYDFDYEILEKEEMERLGM 238 Query: 235 GGLLAVGKGSVHPPRMIVIRYQGTSQWENVTAIVGKGITFDSGGISLKRAPGMEDMISDM 294 G LLAV +GS PP++IV++YQG QWENV +VGKG+TFD+GG LK M DM +DM Sbjct: 239 GALLAVNQGSKQPPKLIVLKYQGKEQWENVIGLVGKGVTFDTGGYCLKPRDSMIDMKTDM 298 Query: 295 GGAAAVLGVMEALGTLRPRINIVMLIPSAENMPAANAFKPGDIVTTLSGRTIEILNTDAE 354 GGAAAVLG MEA+G LRP N++ +IP+ +NM +A AFKP D++T+LSG+TIE+ NTDAE Sbjct: 299 GGAAAVLGAMEAIGELRPEQNVLAVIPATDNMISAEAFKPDDVITSLSGKTIEVRNTDAE 358 Query: 355 GRVVLADALTYSLEWGAERIIDVATLTGAVLSVLGDIATGAVTNNEVMMEALQTASIRAG 414 GR++LADA+TY+ + GA +IDVATLTG V+ LG TGA+TNNE + E L AS+ G Sbjct: 359 GRLILADAITYAKQHGARYLIDVATLTGGVIVALGTDKTGAMTNNEALFEQLLEASMETG 418 Query: 415 EKIWRLPVFPEFREML-SSEVADIRNAAGRYGGASTAGLFIGEFAEGRPWVHLDIAGTAF 473 E IWRLP+ + RE + SS++AD+ N+ GR G A G FIGEFAE PWVHLDIAGTA Sbjct: 419 EFIWRLPITEKDRERVRSSKIADLNNSPGREGHAIMGGAFIGEFAEDTPWVHLDIAGTAT 478 Query: 474 LSKERGVNPKGATGVMVRTLLQYL 497 K+ + P GATGVMVRTL ++ Sbjct: 479 TKKDGDLGPAGATGVMVRTLTAFV 502 >A4ISE0.1 A4ISE0_GEOTN Thermostable leucine aminopeptidase Length = 497 Score = 362 bits (930), Expect = 4e-98, Method: Compositional matrix adjust. Identities = 220/504 (43%), Positives = 294/504 (58%), Gaps = 19/504 (3%) Query: 2 IFIDIKWSSGIQAKTLQGDALCLMIAE-NDMESSEAGEWTE----QISRVSQAGLFGAKL 56 +F WSS + +AL + + E D S AGE+ Q+S + + G AK Sbjct: 1 MFTVKPWSSA----EVVHEALAIGLFEGKDSWSGLAGEYDSRLGGQLSNLRKEGDISAKR 56 Query: 57 NQIYVLPLEGQPGLPVLILAGCGNGLEGTDEXXXXXXXXXXXXXXXXXXXXIIQVPDNLS 116 +I + G+ L G G E T E D + Sbjct: 57 GRIATIHTMLPTGVKRLYFVGLGKKEELTFERLREVFGKLFRTWKQAKRTEAAIALDTFT 116 Query: 117 KLTAVRPHEAGQALTEGLILGAYRRTHYK--REQPVYAGLESAVFHLDRQAEAAESLEWS 174 T V +EA AL E L Y YK + +P YA LES + AA++ E Sbjct: 117 TET-VDSNEAAHALAEAYYLATYEFPGYKQKKSEPDYA-LESLTVYT-----AADAAEIE 169 Query: 175 QGIRQGQAFGEATNLARXXXXXXXXXXXXSALAMAAIEVAERHGFPAEVLDEQEIAQKGM 234 + G +G+ATN AR S LA A+E+A+R+ F E+L+++E+ + GM Sbjct: 170 ASLFVGSVYGKATNSARTLVNTPGNLLTASDLADYAVELAKRYDFDYEILEKEEMERLGM 229 Query: 235 GGLLAVGKGSVHPPRMIVIRYQGTSQWENVTAIVGKGITFDSGGISLKRAPGMEDMISDM 294 G LLAV +GS PP++IV++YQG QWENV +VGKG+TFD+GG LK M DM +DM Sbjct: 230 GALLAVNQGSKQPPKLIVLKYQGKEQWENVIGLVGKGVTFDTGGYCLKPRDSMIDMKTDM 289 Query: 295 GGAAAVLGVMEALGTLRPRINIVMLIPSAENMPAANAFKPGDIVTTLSGRTIEILNTDAE 354 GGAAAVLG MEA+G LRP N++ +IP+ +NM +A AFKP D++T+LSG+TIE+ NTDAE Sbjct: 290 GGAAAVLGAMEAIGELRPEQNVLAVIPATDNMISAEAFKPDDVITSLSGKTIEVRNTDAE 349 Query: 355 GRVVLADALTYSLEWGAERIIDVATLTGAVLSVLGDIATGAVTNNEVMMEALQTASIRAG 414 GR++LADA+TY+ + GA +IDVATLTG V+ LG TGA+TNNE + E L AS+ G Sbjct: 350 GRLILADAITYAKQHGARYLIDVATLTGGVIVALGTDKTGAMTNNEALFEQLLEASMETG 409 Query: 415 EKIWRLPVFPEFREML-SSEVADIRNAAGRYGGASTAGLFIGEFAEGRPWVHLDIAGTAF 473 E IWRLP+ + RE + SS++AD+ N+ GR G A G FIGEFAE PWVHLDIAGTA Sbjct: 410 EFIWRLPITEKDRERVRSSKIADLNNSPGREGHAIMGGAFIGEFAEDTPWVHLDIAGTAT 469 Query: 474 LSKERGVNPKGATGVMVRTLLQYL 497 K+ + P GATGVMVRTL ++ Sbjct: 470 TKKDGDLGPAGATGVMVRTLTAFV 493 >A6TWW9.1 AMPA_ALKMQ Probable cytosol aminopeptidase EC=3.4.11.1 Length = 500 Score = 352 bits (904), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 171/378 (45%), Positives = 252/378 (66%), Gaps = 7/378 (1%) Query: 121 VRPHEAGQALTEGLILGAYRRTHYK---REQPVYAGLESAVFHLDRQAEAAESLEWSQGI 177 + + GQA+ EG LG Y+ HYK +EQ E + + E + + GI Sbjct: 120 ISAEKVGQAIAEGTKLGLYQFNHYKTTAKEQEERVLQEVYILN----EETGITAQLQTGI 175 Query: 178 RQGQAFGEATNLARXXXXXXXXXXXXSALAMAAIEVAERHGFPAEVLDEQEIAQKGMGGL 237 G+ AT +AR + +A A ++++HG E+L+++++ + GMG Sbjct: 176 DTGEKLAHATMIARDLVNEPGNVLTPTEMAKRAQSISQKHGLELEILEKEDMERLGMGCF 235 Query: 238 LAVGKGSVHPPRMIVIRYQGTSQWENVTAIVGKGITFDSGGISLKRAPGMEDMISDMGGA 297 L V GS PP+++V++Y G + + +VGKG+TFDSGGIS+K GM+ M DMGGA Sbjct: 236 LGVTAGSEEPPKLMVLKYNGGEEGGEILGLVGKGLTFDSGGISIKPGEGMDAMKGDMGGA 295 Query: 298 AAVLGVMEALGTLRPRINIVMLIPSAENMPAANAFKPGDIVTTLSGRTIEILNTDAEGRV 357 AAVLG MEA+G L+P+ N++ ++ + ENMP+ A+KPGDI+T+ G+T+EILNTDAEGR+ Sbjct: 296 AAVLGAMEAIGALKPKTNVIAVVGACENMPSGKAYKPGDILTSKGGKTVEILNTDAEGRL 355 Query: 358 VLADALTYSLEWGAERIIDVATLTGAVLSVLGDIATGAVTNNEVMMEALQTASIRAGEKI 417 VL D ++Y+L+ GA R++D+ATLTGA L LG T ++N+E+ ++ ++ AS AGE++ Sbjct: 356 VLVDCVSYALQLGATRLVDLATLTGACLIALGTTTTALISNDELWVKQIEDASKNAGEQV 415 Query: 418 WRLPVFPEFREMLSSEVADIRNAAGRYGGASTAGLFIGEFAEGRPWVHLDIAGTAFLSKE 477 W+LP FPE++EM+ SE+AD++N G+Y GA TAGLF+GEFAEG+PWVH+DIAGT+ KE Sbjct: 416 WQLPSFPEYKEMIKSEIADLKNIGGKYAGAITAGLFVGEFAEGKPWVHMDIAGTSMSDKE 475 Query: 478 RGVNPKGATGVMVRTLLQ 495 +G KG TGV VRTL + Sbjct: 476 KGYITKGGTGVAVRTLYE 493 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.134 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,773,970,643 Number of extensions: 107107078 Number of successful extensions: 278928 Number of sequences better than 1.0e-05: 2088 Number of HSP's gapped: 274987 Number of HSP's successfully gapped: 2090 Length of query: 514 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 374 Effective length of database: 1,741,754,103 Effective search space: 651416034522 Effective search space used: 651416034522 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 134 (56.2 bits)