BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0231.0037.p (591 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KB03.1 B3KB03_9BACI ATP-dependent DNA helicase RecQ 885 0.0 A4J3Z2.1 A4J3Z2_DESRM ATP-dependent DNA helicase RecQ EC=3.6.1.- 667 0.0 C0Z8M4.1 C0Z8M4_BREBN Probable ATP-dependent DNA helicase EC=3.6... 646 0.0 B8FYM8.1 B8FYM8_DESHD ATP-dependent DNA helicase RecQ 627 e-178 C0GGZ5.1 C0GGZ5_9FIRM ATP-dependent DNA helicase RecQ 625 e-177 >B3KB03.1 B3KB03_9BACI ATP-dependent DNA helicase RecQ Length = 627 Score = 885 bits (2287), Expect = 0.0, Method: Compositional matrix adjust. Identities = 415/486 (85%), Positives = 454/486 (93%) Query: 11 MEQAQAELQKYYGYPDFREGQKKIVMNLLEGRDTLGIMPTGGGKSICYQVPALLLPGLTL 70 M+ A+ LQKYYGYPDFR+GQKKIV +LL G+DTLGIMPTGGGKSICYQ+PALL PGLTL Sbjct: 13 MDTAREYLQKYYGYPDFRDGQKKIVASLLTGQDTLGIMPTGGGKSICYQIPALLSPGLTL 72 Query: 71 VISPLISLMKDQVDALTTAGIPAAYINSTLSGKEVNERIRAARRGELKLLYVAPERLELD 130 V+SPLISLMKDQVDALTTAG+ AAYINSTLSGKEVNERIRAA+RG+LKLLYVAPERLELD Sbjct: 73 VVSPLISLMKDQVDALTTAGVAAAYINSTLSGKEVNERIRAAKRGDLKLLYVAPERLELD 132 Query: 131 WFRLEMAGLSISCVAVDEAHCVSQWGHDFRTSYLAVSPFVDELPERPILAAFTATATPEV 190 WFR EMAGL IS VAVDEAHCVSQWGHDFRTSYL+V+PFV LP RPI+AAFTATATPEV Sbjct: 133 WFREEMAGLDISIVAVDEAHCVSQWGHDFRTSYLSVAPFVKGLPNRPIVAAFTATATPEV 192 Query: 191 MEDMVRLLRLRQPGVFMTGLGRDNLAMSVLRGENKREFVLDYTARHSHQPGIVYAATRKE 250 MEDM RLLRL QP VF+TGLGRDNL MSVLRGENKREFVLDY A H+HQPGI+YAATRKE Sbjct: 193 MEDMQRLLRLEQPQVFVTGLGRDNLEMSVLRGENKREFVLDYAASHTHQPGIIYAATRKE 252 Query: 251 VDDLYQRLQASGIAAGRYHAGMSDQERAESQEGFLYDDIRVMVATNAFGMGIDKSNVRYV 310 VDDL QRLQA G+ AGRYHAGMSD ERA+SQE FLYDDIRV+VATNAFGMGIDKSNVRYV Sbjct: 253 VDDLCQRLQAKGLLAGRYHAGMSDAERADSQEAFLYDDIRVIVATNAFGMGIDKSNVRYV 312 Query: 311 IHYNMPKNMEAYVQEAGRAGRDGEPSQCILLFSAQDIMTQKFLIEQNPQDADRKANEYRK 370 IHYNMPKNME+YVQEAGRAGRDGEPSQCILLFSAQDIMTQKFLIEQNPQ+ +RK N+YRK Sbjct: 313 IHYNMPKNMESYVQEAGRAGRDGEPSQCILLFSAQDIMTQKFLIEQNPQEGERKQNDYRK 372 Query: 371 LQQMIDYCYTTRCLRSAQLDYFGEEHGDQPCGICSSCTDERELVDMTVDAQKIFSCIHRM 430 LQQMIDYCYTTRCLRSA LDYFGEEH D+PCG CSSCTD+RELVD+TVDAQKIFSCIHRM Sbjct: 373 LQQMIDYCYTTRCLRSAMLDYFGEEHEDKPCGTCSSCTDDRELVDITVDAQKIFSCIHRM 432 Query: 431 RERFGVALVSSVLKGSRNQKVLQYGFENLPTHGAMSSRTEKEITESINVLISEGYLALSE 490 RERFGV++++SVLKGSR +KVL+YGF+ LPT+G MS+RTEKEI+E+INVLISEG+LAL+E Sbjct: 433 RERFGVSMIASVLKGSRAKKVLEYGFDRLPTYGVMSNRTEKEISETINVLISEGFLALTE 492 Query: 491 GQYPVV 496 GQYPVV Sbjct: 493 GQYPVV 498 >A4J3Z2.1 A4J3Z2_DESRM ATP-dependent DNA helicase RecQ EC=3.6.1.- Length = 707 Score = 667 bits (1721), Expect = 0.0, Method: Compositional matrix adjust. Identities = 308/485 (63%), Positives = 388/485 (80%) Query: 11 MEQAQAELQKYYGYPDFREGQKKIVMNLLEGRDTLGIMPTGGGKSICYQVPALLLPGLTL 70 +++A+ L++Y+GY F+ GQ KI+ N+L+G+DTLGIMPTGGGKSICYQ+PAL+ G TL Sbjct: 2 LKKARQILKQYFGYSSFKSGQDKILNNILQGKDTLGIMPTGGGKSICYQIPALMFQGTTL 61 Query: 71 VISPLISLMKDQVDALTTAGIPAAYINSTLSGKEVNERIRAARRGELKLLYVAPERLELD 130 VISPLISLMKDQVDAL + GI A +INS+L EV +RI + G+ KLLYVAPERLE Sbjct: 62 VISPLISLMKDQVDALNSLGIAATFINSSLDSDEVEKRIFDSGHGKYKLLYVAPERLESK 121 Query: 131 WFRLEMAGLSISCVAVDEAHCVSQWGHDFRTSYLAVSPFVDELPERPILAAFTATATPEV 190 F + LSIS +AVDEAHCVSQWGHDFR SYLA++ V EL +RP++ AFTATAT EV Sbjct: 122 RFINSIKSLSISMLAVDEAHCVSQWGHDFRPSYLAINTVVKELDKRPVVTAFTATATEEV 181 Query: 191 MEDMVRLLRLRQPGVFMTGLGRDNLAMSVLRGENKREFVLDYTARHSHQPGIVYAATRKE 250 +D+VRLL L+ P +++ G R+NL+ +V+RGENK++F+ DY AR+ Q G++YAATRKE Sbjct: 182 TQDIVRLLSLKTPKIYVAGFNRENLSFTVIRGENKKDFISDYLARNKGQAGVIYAATRKE 241 Query: 251 VDDLYQRLQASGIAAGRYHAGMSDQERAESQEGFLYDDIRVMVATNAFGMGIDKSNVRYV 310 VD+L LQ G A G+YHAG++D ER +QE F+YDD+++MVATNAFGMGIDKSNVRYV Sbjct: 242 VDNLEHWLQRKGYAVGKYHAGLNDDERIRNQEKFIYDDLQIMVATNAFGMGIDKSNVRYV 301 Query: 311 IHYNMPKNMEAYVQEAGRAGRDGEPSQCILLFSAQDIMTQKFLIEQNPQDADRKANEYRK 370 IHYNMPKNMEAY QEAGRAGRDGEPSQCILLFS+QD+ QKFLIEQN +RK NEY+K Sbjct: 302 IHYNMPKNMEAYYQEAGRAGRDGEPSQCILLFSSQDVQIQKFLIEQNQVPVERKVNEYKK 361 Query: 371 LQQMIDYCYTTRCLRSAQLDYFGEEHGDQPCGICSSCTDERELVDMTVDAQKIFSCIHRM 430 LQ M+DYC+TT CLR L YFGEE+ + CG CS+C D ELVD TV++QKIFSCI RM Sbjct: 362 LQAMVDYCHTTHCLRGTILKYFGEENVPKECGNCSNCNDYNELVDRTVESQKIFSCILRM 421 Query: 431 RERFGVALVSSVLKGSRNQKVLQYGFENLPTHGAMSSRTEKEITESINVLISEGYLALSE 490 +E++GV+LV++VLKGS+N+KV+Q GF L T+G M T KEI++ I++LI+EGY+ L+E Sbjct: 422 QEQYGVSLVANVLKGSQNKKVIQNGFNRLSTYGLMKEYTTKEISDLIHILIAEGYIYLTE 481 Query: 491 GQYPV 495 GQYPV Sbjct: 482 GQYPV 486 >C0Z8M4.1 C0Z8M4_BREBN Probable ATP-dependent DNA helicase EC=3.6.1.- Length = 591 Score = 646 bits (1667), Expect = 0.0, Method: Compositional matrix adjust. Identities = 307/486 (63%), Positives = 376/486 (77%), Gaps = 1/486 (0%) Query: 11 MEQAQAELQKYYGYPDFREGQKKIVMNLLEGRDTLGIMPTGGGKSICYQVPALLLPGLTL 70 + +AQ L+KY+GY FREGQKKI+ +LL G DT+GIMPTGGGKSICYQVPA+L G+T+ Sbjct: 2 LNKAQEILRKYFGYESFREGQKKIITSLLAGHDTVGIMPTGGGKSICYQVPAMLQDGVTI 61 Query: 71 VISPLISLMKDQVDALTTAGIPAAYINSTLSGKEVNERIRAARRGELKLLYVAPERLELD 130 VISPLISLMKDQVD L + GIPA INS+L EV +R+R A RGE KLLY+APERLE + Sbjct: 62 VISPLISLMKDQVDVLVSMGIPATQINSSLDYSEVRDRLRMAARGEYKLLYIAPERLESE 121 Query: 131 WFRLEMAGLSISCVAVDEAHCVSQWGHDFRTSYLAVSPFVDELPERPILAAFTATATPEV 190 F+ + + IS VAVDEAHCVSQWGHDFR SYLA++ F+ LP+RP++AA TATATPEV Sbjct: 122 AFQNLIQDVPISFVAVDEAHCVSQWGHDFRPSYLAIARFLQSLPQRPLVAALTATATPEV 181 Query: 191 MEDMVRLLRLRQPGVFMTGLGRDNLAMSVLRGENKREFVLDYTARHSHQPGIVYAATRKE 250 ED+ R L L+ +F+TG GRDNL +SV +GEN+REF+ Y + Q GI+YAATRK+ Sbjct: 182 TEDIKRQLELQDERLFITGFGRDNLILSVRKGENRREFIQAYLRANKQQAGIIYAATRKD 241 Query: 251 VDDLYQRLQASGIAAGRYHAGMSDQERAESQEGFLYDDIRVMVATNAFGMGIDKSNVRYV 310 VD L+ L G A +YHAG++++ERA +QE FLYDD+R M+ATNAFGMGIDKSNVRYV Sbjct: 242 VDALHADLDKRGFAVTKYHAGLTEEERAANQEAFLYDDVRTMIATNAFGMGIDKSNVRYV 301 Query: 311 IHYNMPKNMEAYVQEAGRAGRDGEPSQCILLFSAQDIMTQKFLIEQNPQDADRKANEYRK 370 IHYNMPKN+EAY QEAGRAGRDGEPS+CILLF QDI TQ F IEQN +RK EY+K Sbjct: 302 IHYNMPKNLEAYYQEAGRAGRDGEPSECILLFQPQDIQTQTFFIEQNQLLDERKELEYKK 361 Query: 371 LQQMIDYCYTTRCLRSAQLDYFGEEHGDQPCGICSSCTDERELVDMTVDAQKIFSCIHRM 430 L MIDYC T RCL+ + YFGE CG C++CTDE EL D+T++AQKIFSC+ RM Sbjct: 362 LYAMIDYCRTPRCLQQNIVQYFGEADA-VACGRCANCTDETELSDITLEAQKIFSCVKRM 420 Query: 431 RERFGVALVSSVLKGSRNQKVLQYGFENLPTHGAMSSRTEKEITESINVLISEGYLALSE 490 RERFG ALV+ VLKGS+N+KV Q+ F+ LPT+G M EKEI + I +LI+EGYL ++E Sbjct: 421 RERFGAALVAQVLKGSKNKKVTQFSFDELPTYGLMKEYKEKEIADLIQLLIAEGYLQVTE 480 Query: 491 GQYPVV 496 QYP+V Sbjct: 481 SQYPIV 486 >B8FYM8.1 B8FYM8_DESHD ATP-dependent DNA helicase RecQ Length = 728 Score = 627 bits (1617), Expect = e-178, Method: Compositional matrix adjust. Identities = 296/486 (60%), Positives = 369/486 (75%) Query: 11 MEQAQAELQKYYGYPDFREGQKKIVMNLLEGRDTLGIMPTGGGKSICYQVPALLLPGLTL 70 M QA + L++Y+GY FR+GQ K++ +LL+ DT+ IMPTG GKS+ YQ+PALL G+TL Sbjct: 2 MNQALSLLKRYFGYSQFRKGQDKVIHSLLQSSDTVAIMPTGAGKSLSYQIPALLFDGVTL 61 Query: 71 VISPLISLMKDQVDALTTAGIPAAYINSTLSGKEVNERIRAARRGELKLLYVAPERLELD 130 VISPLISLMKDQVD+L AG+PA +INS+LS +EV ERI AR+G KLLY+APERLE + Sbjct: 62 VISPLISLMKDQVDSLHEAGVPATFINSSLSMQEVWERINKARQGRYKLLYIAPERLEAE 121 Query: 131 WFRLEMAGLSISCVAVDEAHCVSQWGHDFRTSYLAVSPFVDELPERPILAAFTATATPEV 190 F + L+IS VAVDEAHCVSQWGHDFR SY + FV+ LP RPI+ AFTATAT EV Sbjct: 122 SFLTLLESLTISFVAVDEAHCVSQWGHDFRPSYRKIGAFVESLPHRPIIGAFTATATQEV 181 Query: 191 MEDMVRLLRLRQPGVFMTGLGRDNLAMSVLRGENKREFVLDYTARHSHQPGIVYAATRKE 250 ED+V LL+L P VF+TG R NL S L+GENK+ F+ Y +H + GI+YAATRKE Sbjct: 182 REDIVSLLKLESPQVFVTGFDRPNLKFSTLKGENKKVFISTYCLQHRSESGIIYAATRKE 241 Query: 251 VDDLYQRLQASGIAAGRYHAGMSDQERAESQEGFLYDDIRVMVATNAFGMGIDKSNVRYV 310 VD L L+ G+ G+YHAGMSD +R ++QE FLYD +MVATNAFGMGIDKSNVR+V Sbjct: 242 VDQLQTYLKGKGLLVGKYHAGMSDLDRQKAQEAFLYDKTPLMVATNAFGMGIDKSNVRFV 301 Query: 311 IHYNMPKNMEAYVQEAGRAGRDGEPSQCILLFSAQDIMTQKFLIEQNPQDADRKANEYRK 370 IHYNMPKNMEAY QEAGRAGRDGEP++CILLF+ QD++ Q++LI+ N + +RK NE++K Sbjct: 302 IHYNMPKNMEAYYQEAGRAGRDGEPAECILLFAPQDVVLQRYLIDNNTFNPERKVNEHKK 361 Query: 371 LQQMIDYCYTTRCLRSAQLDYFGEEHGDQPCGICSSCTDERELVDMTVDAQKIFSCIHRM 430 LQ M DYC+T RCLR L+YFGE CG C +CTD+ ++VD+TVD QKI SC+ RM Sbjct: 362 LQDMADYCHTARCLRKEILEYFGETEIPAECGNCGNCTDDWDVVDITVDTQKILSCVLRM 421 Query: 431 RERFGVALVSSVLKGSRNQKVLQYGFENLPTHGAMSSRTEKEITESINVLISEGYLALSE 490 ERFGV LV+ VLKGS N+K++ + F L T+G MS RT +EI + IN LI+E YL LS Sbjct: 422 GERFGVNLVAEVLKGSGNKKIMDFRFHQLSTYGLMSKRTIQEIKDQINYLIAEDYLRLST 481 Query: 491 GQYPVV 496 G+YPVV Sbjct: 482 GEYPVV 487 >C0GGZ5.1 C0GGZ5_9FIRM ATP-dependent DNA helicase RecQ Length = 591 Score = 625 bits (1612), Expect = e-177, Method: Compositional matrix adjust. Identities = 287/485 (59%), Positives = 372/485 (76%) Query: 12 EQAQAELQKYYGYPDFREGQKKIVMNLLEGRDTLGIMPTGGGKSICYQVPALLLPGLTLV 71 ++A+A L+K +GYP F++GQ ++V +LL R+TL +MPTG GKSICYQ+P+LL G+TLV Sbjct: 4 DEARAVLEKVFGYPSFKDGQAQVVESLLSQRNTLAVMPTGAGKSICYQLPSLLFDGVTLV 63 Query: 72 ISPLISLMKDQVDALTTAGIPAAYINSTLSGKEVNERIRAARRGELKLLYVAPERLELDW 131 +SPLI+LMKDQVDAL + G+PA +INS+L G EV +R+ A G KL+YVAPERLE + Sbjct: 64 VSPLIALMKDQVDALGSLGVPATFINSSLKGSEVKQRMLDAAAGRYKLIYVAPERLEAED 123 Query: 132 FRLEMAGLSISCVAVDEAHCVSQWGHDFRTSYLAVSPFVDELPERPILAAFTATATPEVM 191 FR + + +S +AVDEAHCVSQWGHDFR SY ++PFV LP P++ AFTATATPE+ Sbjct: 124 FRQLVDKIHVSFIAVDEAHCVSQWGHDFRPSYRKIAPFVQSLPRHPLVGAFTATATPEIK 183 Query: 192 EDMVRLLRLRQPGVFMTGLGRDNLAMSVLRGENKREFVLDYTARHSHQPGIVYAATRKEV 251 +D+ RLL L+ F+TG RDNL SVLRGENK+EF+LDY A QPGI+YAATRKEV Sbjct: 184 QDIARLLSLQDANTFVTGFNRDNLYFSVLRGENKKEFILDYLAARPSQPGIIYAATRKEV 243 Query: 252 DDLYQRLQASGIAAGRYHAGMSDQERAESQEGFLYDDIRVMVATNAFGMGIDKSNVRYVI 311 D+LY+ LQ +G+A GRYHAGM + ERA+SQE FL DD+ VMVATNAFGMGIDKSNVR+V+ Sbjct: 244 DNLYEALQKNGVACGRYHAGMREAERAQSQEAFLRDDLLVMVATNAFGMGIDKSNVRFVV 303 Query: 312 HYNMPKNMEAYVQEAGRAGRDGEPSQCILLFSAQDIMTQKFLIEQNPQDADRKANEYRKL 371 HYNMPKNMEAY QEAGRAGRDGE +CILLF QDI+ QKFLIEQ+ RK++E+ KL Sbjct: 304 HYNMPKNMEAYYQEAGRAGRDGERGECILLFGPQDILLQKFLIEQSVYSPKRKSHEFAKL 363 Query: 372 QQMIDYCYTTRCLRSAQLDYFGEEHGDQPCGICSSCTDERELVDMTVDAQKIFSCIHRMR 431 Q M DYC+T +CLR+ L+YFGE + C C +C D+RE VD+T Q + SC+ RM+ Sbjct: 364 QVMADYCHTPQCLRTYILNYFGEADAPKECNNCVNCLDDREAVDITTQTQMVLSCVVRMK 423 Query: 432 ERFGVALVSSVLKGSRNQKVLQYGFENLPTHGAMSSRTEKEITESINVLISEGYLALSEG 491 ER+G +V+ VLKGS+N+K+ +G + L T+G MS T +EI + I L +EGYL+L+EG Sbjct: 424 ERYGTVMVAEVLKGSKNKKLKSFGLDRLSTYGLMSEMTLQEIKDLIGFLTAEGYLSLTEG 483 Query: 492 QYPVV 496 ++P++ Sbjct: 484 KFPLL 488 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.135 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,008,757,039 Number of extensions: 133599613 Number of successful extensions: 324133 Number of sequences better than 1.0e-05: 8984 Number of HSP's gapped: 313155 Number of HSP's successfully gapped: 9057 Length of query: 591 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 449 Effective length of database: 1,722,912,073 Effective search space: 773587520777 Effective search space used: 773587520777 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)