BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0231.0028.p (526 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q893G9.1 Q893G9_CLOTE 67 kDa myosin-crossreactive streptococcal ... 745 0.0 A6TJY6.1 A6TJY6_ALKMQ 67 kDa myosin-cross-reactive antigen famil... 703 0.0 B2UWV1.1 B2UWV1_CLOBA Myosin-cross-reactive antigen family protein 646 0.0 C1IA43.1 C1IA43_9CLOT Myosin-cross-reactive antigen family protein 643 0.0 B2TP59.1 B2TP59_CLOBB 67 kDa myosin-crossreactive streptococcal ... 624 e-177 >Q893G9.1 Q893G9_CLOTE 67 kDa myosin-crossreactive streptococcal antigen Length = 533 Score = 745 bits (1924), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/528 (64%), Positives = 421/528 (79%), Gaps = 2/528 (0%) Query: 1 VKKEYGNSQVYFVGGGIASLAGAAYLVRDCDFPGQNIHIIEEMKILGGSNDGAGNSEQGY 60 +KKEY N QVYFVGGG+ASLAGAA+LVRDC+FPG+NIHI+E M ILGGSNDGAG+ G+ Sbjct: 6 MKKEYENKQVYFVGGGLASLAGAAFLVRDCEFPGKNIHILESMNILGGSNDGAGDPSDGF 65 Query: 61 VIRGGRMLNDEAYENLWELLSTIPSIDHPGQSVREEITAFDDANPTHANARLINKNGEVE 120 + RGGRMLNDE YEN W+LLS+IPS++ G SVR+EI FD+ANPTHANARLI+K+G ++ Sbjct: 66 IARGGRMLNDETYENTWDLLSSIPSLEREGMSVRDEIIEFDNANPTHANARLIDKDGTIQ 125 Query: 121 DVLSMGFDMADRLAMGKLIITPEDKMGKARINDWFA--PHFFQTNFWYMWATTFAFQPWH 178 DV+SMGF+ DR+A+ KLI+TPE+K+ RI DWFA PHFF+TNFWYMW TTFAFQ W Sbjct: 126 DVMSMGFNNEDRMALLKLIVTPEEKIDNIRICDWFASTPHFFETNFWYMWQTTFAFQKWS 185 Query: 179 SAVEFKRYMLRFMHEFPRIQTLEGVTRTPYNQYDSIILPLHKYLEPFGVDFTLKCTVTDL 238 S +EFKRYMLR + EF RIQTLEGVTRTPYNQY+SIILP+ YL+ VDF+LKCTVTDL Sbjct: 186 SLIEFKRYMLRMILEFSRIQTLEGVTRTPYNQYESIILPIKDYLDKAHVDFSLKCTVTDL 245 Query: 239 DFKDGDGITVTKMHVLRQGVPDVIEIAEGDRVIVTNGSMTEGSSLGSMTTAPRLNGKGSS 298 DFKD D ITVT +H + G PDV+++ EGD V+VTNG MT+ +S+GS AP + GKG S Sbjct: 246 DFKDDDSITVTAIHYEKDGKPDVLKLNEGDLVLVTNGCMTDSASIGSTHKAPDMLGKGPS 305 Query: 299 WKLWENIAAKKPGLGNPSSFDDHVDGSKWESFTVTFQDSVFFDLMEKFTRNRAGTGALVT 358 LWENIA+KKPGLGNP F + + S WESFTVT + S + +E +TRN+ G+GALVT Sbjct: 306 AILWENIASKKPGLGNPEPFFGNPELSNWESFTVTCKGSKLLNRIEAYTRNKPGSGALVT 365 Query: 359 FKDSSWFMSVVLAFQPHFRNQPEHVKVFWGYGLYPDKVGDFVKKRMCDCTGEEIMQELIG 418 FKDSSW MS+V+A QPHF+NQP+ + WGYGLY + +GD+VKK MC+CTGEE++ ELI Sbjct: 366 FKDSSWLMSIVVAAQPHFKNQPKDTTILWGYGLYTNNIGDYVKKPMCECTGEELLYELIH 425 Query: 419 HLHFEAHKKEIMATANCIPCMMPYITAQFMPRLNSDRPKVVPEGSTNLAFISQFCEIPDD 478 HLHFE E+M IPCMMPYI +QF PR DRP+VVP+GSTNLA I QFCEIP+D Sbjct: 426 HLHFEDDLDELMENTIVIPCMMPYIDSQFQPRAKKDRPEVVPKGSTNLAMIGQFCEIPED 485 Query: 479 VVFTEEYSVRAARIAVYTLMGVNRPVEPINQYQYDVRTLFSSFVTSFR 526 +VFTEEYSVR+ARIAVY L+G+N+P+ P+ +QYD+R L + TSFR Sbjct: 486 MVFTEEYSVRSARIAVYKLLGLNKPIAPVTPHQYDIRVLLKALNTSFR 533 >A6TJY6.1 A6TJY6_ALKMQ 67 kDa myosin-cross-reactive antigen family protein Length = 554 Score = 703 bits (1815), Expect = 0.0, Method: Compositional matrix adjust. Identities = 334/528 (63%), Positives = 409/528 (77%), Gaps = 2/528 (0%) Query: 1 VKKEYGNSQVYFVGGGIASLAGAAYLVRDCDFPGQNIHIIEEMKILGGSNDGAGNSEQGY 60 +KK+YGN QVYFVGGGIASLAGAAYL+RDC F G+NIHI+E M ILGGSNDG G E G+ Sbjct: 27 MKKDYGNKQVYFVGGGIASLAGAAYLIRDCHFKGENIHILEGMHILGGSNDGMGTPEDGF 86 Query: 61 VIRGGRMLNDEAYENLWELLSTIPSIDHPGQSVREEITAFDDANPTHANARLINKNGEVE 120 V RGGRMLN+E YEN WEL S+IPSI+H G SV +EI AFD A+PTHANARLINK+GEV Sbjct: 87 VCRGGRMLNEETYENFWELFSSIPSIEHEGMSVTDEILAFDHAHPTHANARLINKDGEVL 146 Query: 121 DVLSMGFDMADRLAMGKLIITPEDKMGKARINDWFAPHFFQTNFWYMWATTFAFQPWHSA 180 DV+SMGFD D++AMGKL++TPE+K+ +I+DWF PHFF+TNFWYMW TTFAFQ W S Sbjct: 147 DVMSMGFDKEDQMAMGKLLLTPEEKLDHLKISDWFGPHFFETNFWYMWQTTFAFQKWSSL 206 Query: 181 VEFKRYMLRFMHEFPRIQTLEGVTRTPYNQYDSIILPLHKYLEPFGVDFTLKCTVTDLDF 240 EF+RYM R + EF RIQTLEGVTRTPYNQY+SIILP+ YL+ GVDFT+KCTVTDLDF Sbjct: 207 FEFQRYMFRMIFEFSRIQTLEGVTRTPYNQYESIILPMKAYLDDHGVDFTIKCTVTDLDF 266 Query: 241 KDGDGITVTKMHVLRQGVPDVIEIAEGDRVIVTNGSMTEGSSLGSM-TTAPRLNGKGSSW 299 K+G+GITVT +H Q +I + E D IVTNG MT+G++LG + T AP S Sbjct: 267 KEGEGITVTTIHYQDQDGDGIIRLQEDDICIVTNGCMTDGATLGDLYTPAPLKPEHPISG 326 Query: 300 KLWENIAAKKPGLGNPSSFDDHVDGSKWESFTVTFQDSVFFDLMEKFTRNRAGTGALVTF 359 LW NIAAKK GLG+P F + + + WESFTVT + + ++EK++RN G+GAL+TF Sbjct: 327 DLWANIAAKKSGLGDPKPFFGNAEETNWESFTVTMKGNKLLKMIEKYSRNVPGSGALMTF 386 Query: 360 KDSSWFMSVVLAFQPHFRNQPEHVKVFWGYGLYPDKVGDFVKKRMCDCTGEEIMQELIGH 419 KDSSW MS+V+A QPHF+ Q +FWGY L+ +KVGD+VKK M DCTGEE++ EL+ H Sbjct: 387 KDSSWLMSMVVAAQPHFKAQTADETIFWGYALHTNKVGDYVKKPMRDCTGEEMLIELLHH 446 Query: 420 LHFEAHKKEIMA-TANCIPCMMPYITAQFMPRLNSDRPKVVPEGSTNLAFISQFCEIPDD 478 LHF+ EIM N IPCMMPYI +QF PR +DRP+VVPEGSTNLA ISQF EIP+D Sbjct: 447 LHFDEEMDEIMKDVVNVIPCMMPYIISQFQPRAMTDRPQVVPEGSTNLAMISQFVEIPED 506 Query: 479 VVFTEEYSVRAARIAVYTLMGVNRPVEPINQYQYDVRTLFSSFVTSFR 526 +VFTEE+SVRAARIAVYTLMG+++ + P+ ++YDVRTL + T +R Sbjct: 507 MVFTEEFSVRAARIAVYTLMGLDKKICPVTPHRYDVRTLLKALNTCYR 554 >B2UWV1.1 B2UWV1_CLOBA Myosin-cross-reactive antigen family protein Length = 578 Score = 646 bits (1667), Expect = 0.0, Method: Compositional matrix adjust. Identities = 311/524 (59%), Positives = 387/524 (73%), Gaps = 5/524 (0%) Query: 7 NSQVYFVGGGIASLAGAAYLVRDCDFPGQNIHIIEEMKILGGSNDGAGNSEQGYVIRGGR 66 + QVYFVGGG+ASLAGAAYL+RDC+F G+NIHIIE MKILGGSNDG GN G++ RGGR Sbjct: 54 DKQVYFVGGGLASLAGAAYLIRDCNFKGENIHIIEGMKILGGSNDGGGNPTNGFICRGGR 113 Query: 67 MLNDEAYENLWELLSTIPSIDHPGQSVREEITAFDDANPTHANARLINKNGEVEDVLSMG 126 MLN+E YEN WEL S+IPS++ PG+SV EEI FD +PTHA ARL++K+G ++DV SMG Sbjct: 114 MLNEETYENFWELFSSIPSLEFPGKSVTEEILNFDHLHPTHAQARLVDKDGVIQDVKSMG 173 Query: 127 FDMADRLAMGKLIITPEDKMGKARINDWF--APHFFQTNFWYMWATTFAFQPWHSAVEFK 184 F+ DRLA+GKL+ TPE+K+ I +WF PHFF+TNFWYMW TTFAFQ W S EFK Sbjct: 174 FNNVDRLALGKLMATPEEKLDDMTIEEWFQHTPHFFETNFWYMWQTTFAFQKWSSLFEFK 233 Query: 185 RYMLRFMHEFPRIQTLEGVTRTPYNQYDSIILPLHKYLEPFGVDFTLKCTVTDLDFKDGD 244 RYM R + EF RI+TLEGVTRT YNQY+S+I+PL YLE FGVDF++ TVTDLDFK+G+ Sbjct: 234 RYMERMIFEFSRIETLEGVTRTTYNQYESVIMPLKSYLEGFGVDFSINATVTDLDFKEGE 293 Query: 245 GITVTKMHVLRQGVPDVIEIAEGDRVIVTNGSMTEGSSLGSMTTAPRLNGKGS-SWKLWE 303 ITVT +H+ IE+ + D I+TNG MT+ ++LG T S +LWE Sbjct: 294 KITVTAIHIKDSEGEKTIELKDDDVCIMTNGCMTDNATLGDYNTPAEYKPDSPMSSELWE 353 Query: 304 NIAAKKPGLGNPSSFDDHVDGSKWESFTVTFQDSVFFDLMEKFTRNRAGTGALVTFKDSS 363 +A KK GLGNP F H + + WESFTVT + + L+E+F+ N G+GAL+TFKDSS Sbjct: 354 KVAKKKIGLGNPEPFFKHPEQTNWESFTVTCKGNKLLKLIERFSGNIPGSGALMTFKDSS 413 Query: 364 WFMSVVLAFQPHFRNQPEHVKVFWGYGLYPDKVGDFVKKRMCDCTGEEIMQELIGHLHFE 423 W MS+V+A QPHF+NQP +FWGYGLY D+ GD+VKK M DCTGEEI+ EL+ HLHFE Sbjct: 414 WLMSIVVAAQPHFKNQPLDTTIFWGYGLYTDREGDYVKKPMRDCTGEEILIELLHHLHFE 473 Query: 424 AHKKEIM-ATANCIPCMMPYITAQFMPRLNSDRPKVVPEGSTNLAFISQFCEIPDDVVFT 482 EI + N IPCMMPYI +QF PR SDRPKVVP+GSTN A ISQF EIP+D+VFT Sbjct: 474 DEFDEIKESIVNVIPCMMPYIDSQFQPRKMSDRPKVVPDGSTNFAMISQFVEIPEDMVFT 533 Query: 483 EEYSVRAARIAVYTLMGV-NRPVEPINQYQYDVRTLFSSFVTSF 525 EEYSVRAARIAVYTL + ++ + P+ QY+ + + L + S+ Sbjct: 534 EEYSVRAARIAVYTLFNIKHKKICPVTQYKKNPKILKQALKKSY 577 >C1IA43.1 C1IA43_9CLOT Myosin-cross-reactive antigen family protein Length = 552 Score = 643 bits (1659), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/527 (61%), Positives = 391/527 (74%), Gaps = 5/527 (0%) Query: 4 EYGNSQVYFVGGGIASLAGAAYLVRDCDFPGQNIHIIEEMKILGGSNDGAGNSEQGYVIR 63 E QVYFVGGG+ASLAGAAYLVRDC+F G+NIHIIE M ILGGSNDGAG+ G+V R Sbjct: 25 ENNERQVYFVGGGLASLAGAAYLVRDCNFKGENIHIIEGMHILGGSNDGAGDLINGFVCR 84 Query: 64 GGRMLNDEAYENLWELLSTIPSIDHPGQSVREEITAFDDANPTHANARLINKNGEVEDVL 123 GGRMLN+E YEN WELL ++PS++ PG SV EEI FD +PTHA ARLI+K G ++DV Sbjct: 85 GGRMLNEETYENFWELLRSVPSLEMPGMSVTEEILNFDHLHPTHAQARLIDKYGVIQDVE 144 Query: 124 SMGFDMADRLAMGKLIITPEDKMGKARINDWF--APHFFQTNFWYMWATTFAFQPWHSAV 181 SMGF+ DR+A+GKL+ITPE+K+ I DWF PHFF TNFWYMW TTFAFQ W S Sbjct: 145 SMGFNNTDRMALGKLMITPEEKLDDLTIEDWFKDTPHFFTTNFWYMWQTTFAFQKWSSLF 204 Query: 182 EFKRYMLRFMHEFPRIQTLEGVTRTPYNQYDSIILPLHKYLEPFGVDFTLKCTVTDLDFK 241 EFKRYM R + EF RI+TLEGVTRT YNQY+S+ILPL YL+ FGVDF++ TVTDLDFK Sbjct: 205 EFKRYMERMIFEFSRIETLEGVTRTQYNQYESVILPLKAYLDGFGVDFSINATVTDLDFK 264 Query: 242 DGDGITVTKMHVLRQGVPDVIEIAEGDRVIVTNGSMTEGSSLGSMTTAPRLN-GKGSSWK 300 G+GITVT MH+ + IE+ +GD I+TN MT+ ++LG TAP N K S + Sbjct: 265 PGEGITVTAMHIEDEDGEKTIELNDGDICIMTNACMTDSATLGDFKTAPEYNPDKPISGE 324 Query: 301 LWENIAAKKPGLGNPSSFDDHVDGSKWESFTVTFQDSVFFDLMEKFTRNRAGTGALVTFK 360 LW IA KKPGLGNP F H D + WESFTVT + + L+E+F+ N G+GAL+TFK Sbjct: 325 LWSKIANKKPGLGNPEPFFGHPDETNWESFTVTCKGNKLLKLIEQFSGNVPGSGALMTFK 384 Query: 361 DSSWFMSVVLAFQPHFRNQPEHVKVFWGYGLYPDKVGDFVKKRMCDCTGEEIMQELIGHL 420 DS+W MS+V+A QPHF+NQP +FWGYGLY DK+GD+VKK M +CTGEE++ EL+ HL Sbjct: 385 DSNWLMSIVVAAQPHFKNQPMDTTIFWGYGLYTDKIGDYVKKPMRECTGEELLIELLHHL 444 Query: 421 HFEAHKKEIMAT-ANCIPCMMPYITAQFMPRLNSDRPKVVPEGSTNLAFISQFCEIPDDV 479 HFE EIM T N IPCMMPYI AQF PR +DRP VVPEGSTN A ISQF EIP+D+ Sbjct: 445 HFEDKIDEIMETVVNVIPCMMPYIDAQFQPRKMTDRPNVVPEGSTNFAMISQFVEIPEDM 504 Query: 480 VFTEEYSVRAARIAVYTLMGV-NRPVEPINQYQYDVRTLFSSFVTSF 525 VFTEEYSVRAARIAVYTL+ V N+ V P+ Y+ D + L + S+ Sbjct: 505 VFTEEYSVRAARIAVYTLLNVKNKKVIPVTPYKKDPKILLKALKKSY 551 >B2TP59.1 B2TP59_CLOBB 67 kDa myosin-crossreactive streptococcal antigen-like protein Length = 578 Score = 624 bits (1609), Expect = e-177, Method: Compositional matrix adjust. Identities = 310/524 (59%), Positives = 387/524 (73%), Gaps = 5/524 (0%) Query: 7 NSQVYFVGGGIASLAGAAYLVRDCDFPGQNIHIIEEMKILGGSNDGAGNSEQGYVIRGGR 66 + QVYFVGGG+ SLAGAAYL+RDC+F G+NIHIIE MKILGGSNDG GN G++ RGGR Sbjct: 54 DKQVYFVGGGLGSLAGAAYLIRDCNFKGENIHIIEGMKILGGSNDGGGNPVNGFICRGGR 113 Query: 67 MLNDEAYENLWELLSTIPSIDHPGQSVREEITAFDDANPTHANARLINKNGEVEDVLSMG 126 MLN+E YEN WEL S+IPS++ PG+SV EEI FD +PTHA ARL++K+G ++DV SMG Sbjct: 114 MLNEETYENFWELFSSIPSLEFPGKSVTEEILNFDHLHPTHAQARLVDKDGVIQDVKSMG 173 Query: 127 FDMADRLAMGKLIITPEDKMGKARINDWF--APHFFQTNFWYMWATTFAFQPWHSAVEFK 184 F+ DRLA+GKL+ TPE+K+ I +WF PHFF+TNFWYMW TTFAFQ W S EFK Sbjct: 174 FNKVDRLALGKLMATPEEKLDDMTIEEWFQHTPHFFETNFWYMWQTTFAFQKWSSLFEFK 233 Query: 185 RYMLRFMHEFPRIQTLEGVTRTPYNQYDSIILPLHKYLEPFGVDFTLKCTVTDLDFKDGD 244 RYM R + EF RI+TLEGVTRT YNQY+S+I+PL YLE FGVDF++ TVTDLDFK+G+ Sbjct: 234 RYMERMIFEFSRIETLEGVTRTTYNQYESVIMPLKSYLEKFGVDFSINATVTDLDFKEGE 293 Query: 245 GITVTKMHVLRQGVPDVIEIAEGDRVIVTNGSMTEGSSLGSMTTAPRLNGKGS-SWKLWE 303 ITVT +H+ IE+ + D I+TNG MT+ ++LG +T S +LW+ Sbjct: 294 KITVTAIHIKDSEGEKTIELKDDDVCIMTNGCMTDNATLGDYSTPAEYKPDNPMSSELWK 353 Query: 304 NIAAKKPGLGNPSSFDDHVDGSKWESFTVTFQDSVFFDLMEKFTRNRAGTGALVTFKDSS 363 +A KK GLGNP F H + + WESFTVT + + L+E+F+ N G+GAL+TFKDSS Sbjct: 354 KVAKKKIGLGNPEPFFKHPEQTNWESFTVTCKGNKLLKLIERFSENIPGSGALMTFKDSS 413 Query: 364 WFMSVVLAFQPHFRNQPEHVKVFWGYGLYPDKVGDFVKKRMCDCTGEEIMQELIGHLHFE 423 W MS+V+A QPHF+NQP +FWGYGLY D+ GD+VKK M DCTGEEI+ EL+ HLHFE Sbjct: 414 WLMSIVIAAQPHFKNQPLDTTIFWGYGLYTDREGDYVKKPMRDCTGEEILIELLHHLHFE 473 Query: 424 AHKKEIM-ATANCIPCMMPYITAQFMPRLNSDRPKVVPEGSTNLAFISQFCEIPDDVVFT 482 EI + N IPCMMPYI +QF PR SDRPKVVP+GSTN A ISQF EIP+D+VFT Sbjct: 474 DKFDEIKESIVNVIPCMMPYIDSQFQPRKMSDRPKVVPDGSTNFAMISQFVEIPEDMVFT 533 Query: 483 EEYSVRAARIAVYTLMGV-NRPVEPINQYQYDVRTLFSSFVTSF 525 EEYSVRAARIAVYTL + ++ + P+ QY+ + R L + S+ Sbjct: 534 EEYSVRAARIAVYTLFNIKHKKICPVTQYKKNPRILKQALKKSY 577 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.137 0.427 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,380,199,342 Number of extensions: 152030307 Number of successful extensions: 353277 Number of sequences better than 1.0e-05: 273 Number of HSP's gapped: 351834 Number of HSP's successfully gapped: 284 Length of query: 526 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 385 Effective length of database: 1,732,333,088 Effective search space: 666948238880 Effective search space used: 666948238880 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 134 (56.2 bits)