BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0231.0002.p (603 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KJ97.1 B3KJ97_9BACI Cobyric acid synthase CobQ 613 e-173 B1DGM1.1 B1DGM1_9BACL Cobyric acid synthase CobQ 574 e-161 C5DAP4.1 C5DAP4_9BACI Cobyric acid synthase CobQ 493 e-137 C0Z7I9.1 C0Z7I9_BREBN Cobyric acid synthase 493 e-137 C3J3E8.1 C3J3E8_9BACI Cobyric acid synthase CobQ 471 e-130 >B3KJ97.1 B3KJ97_9BACI Cobyric acid synthase CobQ Length = 524 Score = 613 bits (1581), Expect = e-173, Method: Compositional matrix adjust. Identities = 313/508 (61%), Positives = 378/508 (74%), Gaps = 19/508 (3%) Query: 1 MIQGTASDVGKSLVTAAIGRIMTRDGYRTAPFKSQNMALNSYVTEDGREIGRAQGMQAEA 60 M+QGTASDVGKS+VT A+ RI +DGYRTAP+KSQNMALNSYVT DG+EIGRAQG+QAEA Sbjct: 1 MLQGTASDVGKSIVTTALCRIFLQDGYRTAPYKSQNMALNSYVTLDGKEIGRAQGVQAEA 60 Query: 61 FGITATTDMNPILLKPSGEMSAQIVVHGVPHTALSAREYREKFLPEAKSTVMDALGRLRA 120 GI ATTDMNPIL+KP +M +QIV+HGVP +SA +YR +FLP+AK V+DAL RLR Sbjct: 61 CGIAATTDMNPILIKPIKDMHSQIVIHGVPEMQMSAMDYRTQFLPKAKGIVLDALDRLRE 120 Query: 121 AYDIVLMEGAGSPAEINLKARDIVNMNLAGWADAPVLLVADIDRGGVFAFLVGTLELLEP 180 YDIV+MEGAGSPAEINLK RDIVNMNLAGWAD+PV+LVADIDRGGVFA +VGTLELLEP Sbjct: 121 KYDIVVMEGAGSPAEINLKDRDIVNMNLAGWADSPVILVADIDRGGVFASIVGTLELLEP 180 Query: 181 HERARVKGFIINKFRGDLSLLQPGLDWLEQRTGIPVLGVLPFLPRLRIEAEDSVVLEGTS 240 HE ARVKGFIINKFRGDL+LL+PGLDWLE+RTGIPVLGVLP++ +RIEAEDSVVL+ Sbjct: 181 HEAARVKGFIINKFRGDLALLKPGLDWLEERTGIPVLGVLPYIQDMRIEAEDSVVLDELQ 240 Query: 241 GRLHAERGKELDVAVIRYPRISNFTDFDPLEDEPDTAVRYVSTAVELGTPDVIILPGTKN 300 + +R +LD+ VIRYPRISNFTDFD L E D VR+V + ELGTPDVIILPGTK+ Sbjct: 241 YQRQEKR--DLDIVVIRYPRISNFTDFDALRWERDVVVRFVQSVDELGTPDVIILPGTKD 298 Query: 301 TAADLDYLREQGFPEAIAAALNQGTRQLAGICGGYQMLGLKLLDPHAVESAEPGEREGLG 360 T +DL ++R++G +AI QL GICGGYQMLG +L DPHAVE + E GLG Sbjct: 299 TISDLGFIRDRGLADAILRLTQTRDVQLVGICGGYQMLGERLSDPHAVEGS-AREAAGLG 357 Query: 361 FLPLSTSFLRQKTTVRATGLLAQDHPLPLYGGEAASATAAELPVEGYEIHMGTT---TNH 417 LP+ T+F ++K TVR G L+Q+HPL L S T A + YEIHMG T T Sbjct: 358 LLPMRTAFSKKKKTVRVRGELSQEHPLKL----VLSDTKAISAIGAYEIHMGVTERSTEP 413 Query: 418 DPASVRSLFQLK---------GPDGSMQQEGWGTPEGRVWGTYLHGLFHNDALRRAWLDG 468 + R+LF ++ G D EG T +GR+WG YLHGLF NDA RR+WL+G Sbjct: 414 GGSEHRTLFSIEADSADSLEAGEDIQAHPEGLATADGRIWGCYLHGLFDNDAFRRSWLNG 473 Query: 469 LRQSKGLAPLGQTFSAAALREQEFDRLG 496 +R +KGL + +TF A + E++R+ Sbjct: 474 IRVNKGLDAICETFQAEERKLAEYNRVA 501 >B1DGM1.1 B1DGM1_9BACL Cobyric acid synthase CobQ Length = 502 Score = 574 bits (1479), Expect = e-161, Method: Compositional matrix adjust. Identities = 304/496 (61%), Positives = 364/496 (73%), Gaps = 22/496 (4%) Query: 1 MIQGTASDVGKSLVTAAIGRIMTRDGYRTAPFKSQNMALNSYVTEDGREIGRAQGMQAEA 60 M+QGTASDVGKS++T A+ RI +DG +TAPFKSQNMALNSYVT DG+EIGRAQG+QAEA Sbjct: 8 MVQGTASDVGKSVLTTALCRIFVQDGRKTAPFKSQNMALNSYVTLDGKEIGRAQGVQAEA 67 Query: 61 FGITATTDMNPILLKPSGEMSAQIVVHGVPHTALSAREYREKFLPEAKSTVMDALGRLRA 120 GI ATTDMNPIL+KP+GEM AQIVVHG P +SA YRE+++P A+ V +AL RLR Sbjct: 68 CGIAATTDMNPILIKPTGEMKAQIVVHGKPLEEMSAWRYREEYIPLAEGIVREALDRLRG 127 Query: 121 AYDIVLMEGAGSPAEINLKARDIVNMNLAGWADAPVLLVADIDRGGVFAFLVGTLELLEP 180 +DI+++EGAGSPAEINLK RDIVNM +A WADAPV+LVADIDRGGVFA +VGT+ELLE Sbjct: 128 EHDIIVLEGAGSPAEINLKDRDIVNMRMAKWADAPVVLVADIDRGGVFASIVGTMELLEE 187 Query: 181 HERARVKGFIINKFRGDLSLLQPGLDWLEQRTGIPVLGVLPFLPRLRIEAEDSVVLEGTS 240 ER+RVKGFIINKFRGD+SLLQ GLDWLE+RTGIPVLGV+P+LPRL IEAEDSVVLE Sbjct: 188 DERSRVKGFIINKFRGDISLLQSGLDWLEERTGIPVLGVIPYLPRLDIEAEDSVVLE--- 244 Query: 241 GRLHAERGKELDVAVIRYPRISNFTDFDPLEDEPDTAVRYVSTAVELGTPDVIILPGTKN 300 R +LD+AVIR PRISNFTDFDPLE EPD VRYV +LG PDVI++PG+KN Sbjct: 245 KRTDQAGNGDLDIAVIRLPRISNFTDFDPLEAEPDVHVRYVEGMDQLGQPDVILIPGSKN 304 Query: 301 TAADLDYLREQGFPEAIAAALNQGTRQLAGICGGYQMLGLKLLDPHAVESAEPGEREGLG 360 T DL +L++ G +AIA G +AGICGGYQMLG KL DPH VESA E +GLG Sbjct: 305 TIEDLLFLKKTGLAKAIAEHAASGC-YVAGICGGYQMLGQKLYDPHQVESAYV-ESDGLG 362 Query: 361 FLPLSTSFLRQKTTVRATGLLAQDHP-LPLYGGEAASATAAELPVEGYEIHMGTTTNHDP 419 FLPLST+F K T R +G ++ HP P G L +EGYEIHMG TT Sbjct: 363 FLPLSTTFYTNKRTERVSGNVSFGHPDWPDMQG---------LAIEGYEIHMGQTTALST 413 Query: 420 ASVRSLFQLKGPDGSMQQEGWGTPEGRVWGTYLHGLFHNDALRRAWLDGLRQSKGLAPLG 479 A L + G Q EG + +GR++GTY+HG+FHNDA RR +L+ +R K LAP+ Sbjct: 414 A--LPLLSING-----QDEGSISEDGRIFGTYVHGIFHNDAFRRQYLNLVRARKNLAPVE 466 Query: 480 QTFSAAALREQEFDRL 495 + + + FDRL Sbjct: 467 AILPFRSRQLEAFDRL 482 >C5DAP4.1 C5DAP4_9BACI Cobyric acid synthase CobQ Length = 503 Score = 493 bits (1270), Expect = e-137, Method: Compositional matrix adjust. Identities = 257/496 (51%), Positives = 335/496 (67%), Gaps = 24/496 (4%) Query: 1 MIQGTASDVGKSLVTAAIGRIMTRDGYRTAPFKSQNMALNSYVTEDGREIGRAQGMQAEA 60 M QGT SD GKS++ A RI ++G++TAPFKSQNM+LNSYVT DG+EIGRAQG+QAEA Sbjct: 8 MFQGTHSDAGKSIIATAFCRIFAKNGWKTAPFKSQNMSLNSYVTVDGKEIGRAQGIQAEA 67 Query: 61 FGITATTDMNPILLKPSGEMSAQIVVHGVPHTALSAREYREKFLPEAKSTVMDALGRLRA 120 G+ ATTDMNPIL+KPS E +QIVVHG P+ + A YR +F + + + ++L L Sbjct: 68 AGVVATTDMNPILIKPSREHESQIVVHGKPYKNMQAFAYRGEFFEKGLAIIHESLDVLMN 127 Query: 121 AYDIVLMEGAGSPAEINLKARDIVNMNLAGWADAPVLLVADIDRGGVFAFLVGTLELLEP 180 YD +++EGAGSPAEINL R++VNM +A A+APV+L+ DI+RGGVFA LVGTL+LL+ Sbjct: 128 EYDRLVIEGAGSPAEINLNDRELVNMRVARMANAPVVLIGDIERGGVFASLVGTLQLLDK 187 Query: 181 HERARVKGFIINKFRGDLSLLQPGLDWLEQRTGIPVLGVLPFLPRLRIEAEDSVVLEGTS 240 +R R+ G IINKFRGDL+LL+PGLDW EQ TG+PVLGV+P+L L I+AEDSV LE S Sbjct: 188 EDRKRIIGVIINKFRGDLALLKPGLDWFEQYTGVPVLGVVPYLEDLHIDAEDSVSLEQMS 247 Query: 241 GRLHAERGKELDVAVIRYPRISNFTDFDPLEDEPDTAVRYVSTAVELGTPDVIILPGTKN 300 ++ + K++D+AVIRYP+ISNFTD DP EPD VR+V+TA +LG PD++ILPG+KN Sbjct: 248 TAVNPD--KDIDIAVIRYPKISNFTDVDPFLTEPDCHVRFVATAAQLGQPDLLILPGSKN 305 Query: 301 TAADLDYLREQGFPEAIAAALNQGTRQLAGICGGYQMLGLKLLDPHAVESAEPGEREGLG 360 T DL Y+++ G E IA + GICGGYQMLG ++ DP VE+ E GL Sbjct: 306 TIEDLLYMKKNGIAEQIAQLNKHHRVTIVGICGGYQMLGARIRDPFGVETP-LREISGLN 364 Query: 361 FLPLSTSFLRQKTTVRATGLLAQDHPLPLYGGEAASATAAELPVEGYEIHMGTTTNHDPA 420 LP+ T+ R+KTTV + G+L + T V+GYEIHMG + D Sbjct: 365 LLPIETTLERKKTTVLSEGIL--------------TFTGERFFVKGYEIHMGRSQPLDGN 410 Query: 421 SVRSLFQLKGPDGSMQQEGWGTPEGRVWGTYLHGLFHNDALRRAWLDGLRQSKGLAPLGQ 480 ++G + EG + + RV GTY H LFHNDA R A L+ +R+ KGLAP+ Sbjct: 411 I--PFIHVQG-----RAEGAKSKDERVIGTYFHDLFHNDAFREALLNKIRREKGLAPIYG 463 Query: 481 TFSAAALREQEFDRLG 496 S +REQ FDRL Sbjct: 464 RQSFRTIREQAFDRLA 479 >C0Z7I9.1 C0Z7I9_BREBN Cobyric acid synthase Length = 498 Score = 493 bits (1268), Expect = e-137, Method: Compositional matrix adjust. Identities = 263/518 (50%), Positives = 348/518 (67%), Gaps = 30/518 (5%) Query: 1 MIQGTASDVGKSLVTAAIGRIMTRDGYRTAPFKSQNMALNSYVTEDGREIGRAQGMQAEA 60 M+QGT+SD GKS + A+ RI +DGY+TAPFKSQNMALNSYVT DG+EIGRAQG+QAEA Sbjct: 1 MVQGTSSDAGKSAIATALCRIFAQDGYKTAPFKSQNMALNSYVTLDGKEIGRAQGVQAEA 60 Query: 61 FGITATTDMNPILLKPSGEMSAQIVVHGVPHTALSAREYREKFLPEAKSTVMDALGRLRA 120 GI ATTDMNPIL+KP+ + +QIVV+G P+ + A YR +F + + +A RL + Sbjct: 61 AGILATTDMNPILIKPTRDSESQIVVNGEPYGNMKAFAYRTEFYDKGLRIIEEAYQRLAS 120 Query: 121 AYDIVLMEGAGSPAEINLKARDIVNMNLAGWADAPVLLVADIDRGGVFAFLVGTLELLEP 180 +Y+ +++EGAGSPAE+NL R++VNM +A +APV+LVADI+RGGVFA LVGTL+LLEP Sbjct: 121 SYERIVIEGAGSPAEVNLNDRELVNMRVARLTNAPVILVADIERGGVFASLVGTLQLLEP 180 Query: 181 HERARVKGFIINKFRGDLSLLQPGLDWLEQRTGIPVLGVLPFLPRLRIEAEDSVVLEGTS 240 +R RV G IIN+FRGDL+LLQPGLDW E+ TG PVLGV+PF+P L I+AEDS++L Sbjct: 181 EDRDRVVGVIINRFRGDLTLLQPGLDWFEEYTGKPVLGVVPFIPDLWIDAEDSLILHRYQ 240 Query: 241 GRLHAERGKELDVAVIRYPRISNFTDFDPLEDEPDTAVRYVSTAVELGTPDVIILPGTKN 300 G+ E +E+D+AV+RYPRISNFTD DP EPD +R+V+ ELG PD+I+LPG+KN Sbjct: 241 GQ--RETPREIDIAVLRYPRISNFTDVDPFFVEPDCRMRFVTRLEELGEPDLIVLPGSKN 298 Query: 301 TAADLDYLREQGFPEAIAAALNQGTRQLAGICGGYQMLGLKLLDPHAVESAEPGEREGLG 360 T DL +LRE G A+ ++G + G+CGGYQMLG + DP VES + +GLG Sbjct: 299 TLEDLQFLRETGLAAAVKDLHHKGKTYIVGLCGGYQMLGEAIHDPAGVESP-LQQLDGLG 357 Query: 361 FLPLSTSFLRQKTTVRATGLLAQDHPLPLYGGEAASATAAELPVEGYEIHMGTTT---NH 417 +P+ T+ ++KTTV L GEA A +L VEGYEIHMG +T N Sbjct: 358 LIPMITTMEQKKTTV-------------LSRGEAVFA-KEKLTVEGYEIHMGQSTYSRND 403 Query: 418 DPASVRSLFQLKGPDGSMQQEGWGTPEGRVWGTYLHGLFHNDALRRAWLDGLRQSKGLAP 477 P Q++G + EG+ E ++ GTY HGLFHND R L+ +R+ KGL+P Sbjct: 404 FP-----FIQMEG-----RTEGYCQEERQLIGTYFHGLFHNDHFRTLLLNAIREQKGLSP 453 Query: 478 LGQTFSAAALREQEFDRLGGGXXXXARALTWLPSMRSW 515 + S ALREQ +D L + T M+++ Sbjct: 454 ITDRPSFVALREQGYDLLADTVRRHVKLDTIEEYMKAF 491 >C3J3E8.1 C3J3E8_9BACI Cobyric acid synthase CobQ Length = 503 Score = 471 bits (1211), Expect = e-130, Method: Compositional matrix adjust. Identities = 255/495 (51%), Positives = 335/495 (67%), Gaps = 25/495 (5%) Query: 1 MIQGTASDVGKSLVTAAIGRIMTRDGYRTAPFKSQNMALNSYVTEDGREIGRAQGMQAEA 60 M QGT SD GKS++ A R+ +DG++TAPFKSQNM+LNSYVT DG EIGRAQG+QAEA Sbjct: 8 MFQGTHSDAGKSVIATAFCRMFAQDGWKTAPFKSQNMSLNSYVTPDGNEIGRAQGIQAEA 67 Query: 61 FGITATTDMNPILLKPSGEMSAQIVVHGVPHTALSAREYREKFLPEAKSTVMDALGRLRA 120 G+ A +MNPIL+KPS E +QIVV G P+ + A YR +F + + + +L L Sbjct: 68 AGVAARAEMNPILIKPSREHESQIVVLGKPYGNMQAFAYRNEFFHQGLAVIRQSLETLMN 127 Query: 121 AYDIVLMEGAGSPAEINLKARDIVNMNLAGWADAPVLLVADIDRGGVFAFLVGTLELLEP 180 YD +++EGAGSPAE+NL R++VNM +A A+APV+L+ DI+RGGVFA LVGTL LLEP Sbjct: 128 EYDRIVIEGAGSPAEVNLNDRELVNMRIARLANAPVVLIGDIERGGVFASLVGTLSLLEP 187 Query: 181 HERARVKGFIINKFRGDLSLLQPGLDWLEQRTGIPVLGVLPFLPRLRIEAEDSVVLEGTS 240 +R RV G IINKFRGD++LL+PGLDW EQ TG+PVLGV+P+LP L I+AEDS+ LE + Sbjct: 188 EDRKRVIGVIINKFRGDVALLKPGLDWFEQHTGVPVLGVVPYLPDLAIDAEDSLSLERFA 247 Query: 241 GRLHAERGKELDVAVIRYPRISNFTDFDPLEDEPDTAVRYVSTAVELGTPDVIILPGTKN 300 + E +DVAVIR P+I+NFTD DPL EPD VR V+ A ELG PDVI+LPG+KN Sbjct: 248 SSVGGEEA--IDVAVIRCPKIANFTDIDPLLAEPDCRVRLVTHADELGAPDVIVLPGSKN 305 Query: 301 TAADLDYLREQGFPEAIAAALNQGTRQLAGICGGYQMLGLKLLDPHAVESAEPGEREGLG 360 T DL Y++++G I + +N+G ++ G+CGGYQMLG + DP+ VE+ P E +GLG Sbjct: 306 TIEDLIYMKKRGLASRIVSLVNKGKARVVGLCGGYQMLGAVIRDPYGVETPLP-EVKGLG 364 Query: 361 FLPLSTSFLRQKTTVRATGLLAQDHPLPLYGGEAASATAAELPVEGYEIHMGTTTNHDPA 420 LP+ T+ R K T+R G+L + GE S V+GYEIHMG + A Sbjct: 365 LLPIETTLERTKITIRTEGMLT-------WAGERFS-------VQGYEIHMGRS-----A 405 Query: 421 SVRSLFQLKGPDGSMQQEGWGTPEGRVWGTYLHGLFHNDALRRAWLDGLRQSKGLAPLGQ 480 + L DG + EG + RV GTY+H LFHNDA R A+ + +R+ KG+AP G Sbjct: 406 PLPGYAPLIEADG--RHEGAKHSDERVLGTYMHDLFHNDAFRTAFFNSIRRQKGIAPSG- 462 Query: 481 TFSAAALREQEFDRL 495 +L+E+ FDRL Sbjct: 463 VRPFRSLKEKAFDRL 477 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.137 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,739,679,155 Number of extensions: 164955663 Number of successful extensions: 386157 Number of sequences better than 1.0e-05: 788 Number of HSP's gapped: 381834 Number of HSP's successfully gapped: 788 Length of query: 603 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 461 Effective length of database: 1,722,912,073 Effective search space: 794262465653 Effective search space used: 794262465653 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)