BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0225.0012.p (260 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KAZ5.1 B3KAZ5_9BACI Beta-lactamase domain protein 392 e-107 B1HQC5.1 B1HQC5_LYSSC Possible Zn-dependent hydrolase, beta-lact... 360 5e-98 A3I4E3.1 A3I4E3_9BACI Possible Zn-dependent hydrolase, beta-lact... 357 7e-97 C3C0N7.1 C3C0N7_BACTU Zn-dependent hydrolase, beta-lactamase super 344 5e-93 C2QRC4.1 C2QRC4_BACCE Zn-dependent hydrolase, beta-lactamase super 344 5e-93 >B3KAZ5.1 B3KAZ5_9BACI Beta-lactamase domain protein Length = 268 Score = 392 bits (1007), Expect = e-107, Method: Compositional matrix adjust. Identities = 187/260 (71%), Positives = 218/260 (83%) Query: 1 MINDPWFTVQQIDETTFAISEYGHWEKVHSFLLLGQERAALIDTGLGIGNIRTITDQLTN 60 +I+D WFTV Q+DE TFAISEYGHWEKVHSFLL+G ERAALIDTGLGI ++R ITDQLT+ Sbjct: 9 VIDDAWFTVSQLDEGTFAISEYGHWEKVHSFLLIGDERAALIDTGLGIDDMRRITDQLTD 68 Query: 61 LPIDVLTTHVHTDHIGSHGEYERIFVHEGDLDWLVHGIKGLSLEQIRRDIGRDISQPVPE 120 LPI VLTTHVH DHIGSHG+Y I+VH+ + DWLV GIK LS+EQIR+DI RDI++PVP+ Sbjct: 69 LPIMVLTTHVHADHIGSHGQYGEIYVHKAEEDWLVSGIKKLSIEQIRKDISRDITKPVPD 128 Query: 121 GFDPQTYRPFQGEPAGLLRDGDTVELGGRALAVYHTPGHSPGHLVFWDTLNGYLFTGDLL 180 FDP Y P++G+P GLLRDGD +ELGGR+L +YHTPGHSPGH+ ++ GYLFTGDLL Sbjct: 129 SFDPAAYTPYRGQPTGLLRDGDVIELGGRSLVIYHTPGHSPGHIAVFEPNRGYLFTGDLL 188 Query: 181 YDGTPVYAFYPSTSPVDLVASLERIAEIDGVQRIYGSHNTLGLHPQILSEVKHAVQLLRR 240 YD TPVYAFYP+TSP DLV SLERIA I+GV RI+GSHNTLGL P L VK AVQ LR Sbjct: 189 YDETPVYAFYPTTSPEDLVNSLERIANIEGVNRIFGSHNTLGLDPAWLDLVKEAVQELRE 248 Query: 241 NDLVKFGTGLHTFNGFSIQF 260 DLV+FGTG+H FNGFS+QF Sbjct: 249 KDLVRFGTGIHRFNGFSVQF 268 >B1HQC5.1 B1HQC5_LYSSC Possible Zn-dependent hydrolase, beta-lactamase superfamily Length = 262 Score = 360 bits (925), Expect = 5e-98, Method: Compositional matrix adjust. Identities = 166/259 (64%), Positives = 212/259 (81%) Query: 2 INDPWFTVQQIDETTFAISEYGHWEKVHSFLLLGQERAALIDTGLGIGNIRTITDQLTNL 61 IND WFTV++I+ T+AISEYGHWEKVHSFLLLG+++A LIDTGLGI NI+ I+ QLT+L Sbjct: 4 INDAWFTVEEINNETYAISEYGHWEKVHSFLLLGEKQAVLIDTGLGIDNIQRISKQLTSL 63 Query: 62 PIDVLTTHVHTDHIGSHGEYERIFVHEGDLDWLVHGIKGLSLEQIRRDIGRDISQPVPEG 121 PI V+TTHVH DHIGSHG ++ I+VH+ ++DWL+HGI LS+EQIR D+GR+I+ P P+ Sbjct: 64 PISVITTHVHWDHIGSHGAFDDIYVHKDEVDWLIHGIPKLSIEQIRTDVGRNITIPTPKT 123 Query: 122 FDPQTYRPFQGEPAGLLRDGDTVELGGRALAVYHTPGHSPGHLVFWDTLNGYLFTGDLLY 181 F+P Y+PFQG+P+G+L DGD +++G R L++ HTPGHSPGH+ D GYLFTGDLLY Sbjct: 124 FNPSDYKPFQGQPSGVLEDGDIIDIGNRKLSILHTPGHSPGHIALLDHKYGYLFTGDLLY 183 Query: 182 DGTPVYAFYPSTSPVDLVASLERIAEIDGVQRIYGSHNTLGLHPQILSEVKHAVQLLRRN 241 D P+YAF+P+TSP DLV SLE+IA + + +I+GSH+TLGL P IL EVK AV LR+N Sbjct: 184 DQAPIYAFFPTTSPEDLVQSLEKIANLSSLTKIFGSHHTLGLDPSILLEVKKAVITLRKN 243 Query: 242 DLVKFGTGLHTFNGFSIQF 260 +LV FGTG+H FNGFSIQF Sbjct: 244 NLVHFGTGIHRFNGFSIQF 262 >A3I4E3.1 A3I4E3_9BACI Possible Zn-dependent hydrolase, beta-lactamase superfamily protein Length = 262 Score = 357 bits (915), Expect = 7e-97, Method: Compositional matrix adjust. Identities = 165/259 (63%), Positives = 209/259 (80%) Query: 2 INDPWFTVQQIDETTFAISEYGHWEKVHSFLLLGQERAALIDTGLGIGNIRTITDQLTNL 61 IND WFTV++I+ T+AISEYGHWEKVHSFLL+G++RA LIDTGLGI NI+ I+ QLT++ Sbjct: 4 INDEWFTVEEINNETYAISEYGHWEKVHSFLLIGEKRAVLIDTGLGIDNIQRISKQLTSI 63 Query: 62 PIDVLTTHVHTDHIGSHGEYERIFVHEGDLDWLVHGIKGLSLEQIRRDIGRDISQPVPEG 121 PI V+TTHVH DHIGSHG + I+VH+ ++DWL+HGI LS+EQIR D+GR+I+ P P+ Sbjct: 64 PITVITTHVHWDHIGSHGAFHDIYVHKEEVDWLIHGIPKLSIEQIRTDVGRNITLPTPKT 123 Query: 122 FDPQTYRPFQGEPAGLLRDGDTVELGGRALAVYHTPGHSPGHLVFWDTLNGYLFTGDLLY 181 F+P Y+PFQG+P+G+L DGD + +G R L++ HTPGHSPGH+ D GYLFTGDLLY Sbjct: 124 FNPSHYKPFQGQPSGVLEDGDVINIGNRKLSILHTPGHSPGHIALLDHKYGYLFTGDLLY 183 Query: 182 DGTPVYAFYPSTSPVDLVASLERIAEIDGVQRIYGSHNTLGLHPQILSEVKHAVQLLRRN 241 D P+YAF+P+TSP DLV SLE+IA + + +I+GSH+TLGL P IL EVK AV LR N Sbjct: 184 DQAPIYAFFPTTSPEDLVQSLEKIANLPSLTKIFGSHHTLGLDPSILLEVKKAVITLREN 243 Query: 242 DLVKFGTGLHTFNGFSIQF 260 +LV FGTG+H FNGFSIQF Sbjct: 244 NLVHFGTGIHRFNGFSIQF 262 >C3C0N7.1 C3C0N7_BACTU Zn-dependent hydrolase, beta-lactamase super Length = 265 Score = 344 bits (882), Expect = 5e-93, Method: Compositional matrix adjust. Identities = 159/260 (61%), Positives = 205/260 (78%), Gaps = 1/260 (0%) Query: 1 MINDPWFTVQQIDETTFAISEYGHWEKVHSFLLLGQERAALIDTGLGIGNIRTITDQLTN 60 +++DPWFTV+QI + T+AISEYGHWEKVHSFLL+G A LIDTGLGI N++ ITDQLTN Sbjct: 7 ILHDPWFTVKQIAQNTYAISEYGHWEKVHSFLLIGDTTALLIDTGLGIDNLKRITDQLTN 66 Query: 61 LPIDVLTTHVHTDHIGSHGEYERIFVHEGDLDWLVHGIKGLSLEQIRRDIGRDISQPVPE 120 LPI V+TTHVH DHIGSH +YE I+VH + DWL++GIKGL + QIR DI RDI+ P P+ Sbjct: 67 LPITVVTTHVHWDHIGSHAQYEEIYVHALEEDWLINGIKGLPITQIRHDIARDITLPTPK 126 Query: 121 GFDPQTYRPFQGEPAGLLRDGDTVELGGRALAVYHTPGHSPGHLVFWDTLNGYLFTGDLL 180 F P+ ++PFQG P LL+DGD +++G R + + HTPGHSPGH+ +D +LFTGDLL Sbjct: 127 TFQPEAFKPFQGTPKKLLQDGDIIDIGNRKIQIIHTPGHSPGHICLYDYETAFLFTGDLL 186 Query: 181 YDGTPVYAFYPSTSPVDLVASLERIAEIDGVQRIYGSHNTLGLHPQILSEVKHAVQLLRR 240 Y+GT ++AFYPST+PVDLV SL +I + +++I+GSH+TLGL P IL EVK+A+Q L Sbjct: 187 YEGT-IFAFYPSTNPVDLVQSLNKITNVFPIKQIFGSHHTLGLSPVILKEVKYAIQYLND 245 Query: 241 NDLVKFGTGLHTFNGFSIQF 260 +L+K GTG+HTF FSIQF Sbjct: 246 KELIKHGTGIHTFQNFSIQF 265 >C2QRC4.1 C2QRC4_BACCE Zn-dependent hydrolase, beta-lactamase super Length = 265 Score = 344 bits (882), Expect = 5e-93, Method: Compositional matrix adjust. Identities = 159/260 (61%), Positives = 205/260 (78%), Gaps = 1/260 (0%) Query: 1 MINDPWFTVQQIDETTFAISEYGHWEKVHSFLLLGQERAALIDTGLGIGNIRTITDQLTN 60 +++DPWFTV+QI + T+AISEYGHWEKVHSFLL+G A LIDTGLGI N++ ITDQLTN Sbjct: 7 ILHDPWFTVKQIAQNTYAISEYGHWEKVHSFLLIGDTTALLIDTGLGIDNLKRITDQLTN 66 Query: 61 LPIDVLTTHVHTDHIGSHGEYERIFVHEGDLDWLVHGIKGLSLEQIRRDIGRDISQPVPE 120 LPI V+TTHVH DHIGSH +YE I+VH + DWL++GIKGL + QIR DI RDI+ P P+ Sbjct: 67 LPITVVTTHVHWDHIGSHAQYEEIYVHALEEDWLINGIKGLPITQIRHDIARDITLPTPK 126 Query: 121 GFDPQTYRPFQGEPAGLLRDGDTVELGGRALAVYHTPGHSPGHLVFWDTLNGYLFTGDLL 180 F P+ ++PFQG P LL+DGD +++G R + + HTPGHSPGH+ +D +LFTGDLL Sbjct: 127 TFQPEAFKPFQGTPKKLLQDGDIIDIGNRKIQIIHTPGHSPGHICLYDYETAFLFTGDLL 186 Query: 181 YDGTPVYAFYPSTSPVDLVASLERIAEIDGVQRIYGSHNTLGLHPQILSEVKHAVQLLRR 240 Y+GT ++AFYPST+PVDLV SL +I + +++I+GSH+TLGL P IL EVK+A+Q L Sbjct: 187 YEGT-IFAFYPSTNPVDLVQSLNKITNVFPIKQIFGSHHTLGLSPVILKEVKYAIQYLND 245 Query: 241 NDLVKFGTGLHTFNGFSIQF 260 +L+K GTG+HTF FSIQF Sbjct: 246 KELIKHGTGIHTFQNFSIQF 265 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.142 0.442 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,737,760,360 Number of extensions: 80263530 Number of successful extensions: 202562 Number of sequences better than 1.0e-05: 797 Number of HSP's gapped: 202511 Number of HSP's successfully gapped: 803 Length of query: 260 Length of database: 3,060,696,203 Length adjustment: 133 Effective length of query: 127 Effective length of database: 1,807,701,208 Effective search space: 229578053416 Effective search space used: 229578053416 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 130 (54.7 bits)