BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0217.0024.p (255 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K414.1 B3K414_9BACI Xylose isomerase domain protein TIM barrel 216 2e-54 B1DJ61.1 B1DJ61_9BACL Xylose isomerase domain protein TIM barrel 211 4e-53 B0K7A8.1 B0K7A8_THEP3 Xylose isomerase domain protein TIM barrel 179 2e-43 Q8R8P6.1 Q8R8P6_THETN Sugar phosphate isomerases/epimerases 178 3e-43 B7R6U3.1 B7R6U3_9THEO AP endonuclease, family 2 178 3e-43 >B3K414.1 B3K414_9BACI Xylose isomerase domain protein TIM barrel Length = 257 Score = 216 bits (549), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 107/253 (42%), Positives = 152/253 (60%), Gaps = 5/253 (1%) Query: 2 LKIGLQLYTLREELEQDFEGTIRKVAELGYAGVEFFHYFGRTAEQVNALLQETGLTALGA 61 + IGLQ+YTLR+E QDF GT+RKVAELGY GVEF Y AE++ LLQE GL A+G+ Sbjct: 4 MNIGLQMYTLRDETAQDFRGTLRKVAELGYEGVEFAGYGDIPAEEMKTLLQELGLKAIGS 63 Query: 62 HRPYDAMLNDTEQEISFNLSIGNRNLIVPYLTEEQR----NWEEVAVNLRKIGEQCSARG 117 H + D ++EI + +IG + ++ PY+ EE R +W+ + L ++G + +G Sbjct: 64 HVGLHLLRADLQKEIDYLKTIGAKYMMCPYVAEEDRKDAEDWKNLFSFLEEVGAEARKQG 123 Query: 118 AVLSYHNHDFEFKEQFGGRTAFDGIFEEVPADLLQVEMDTCWVYYAGYDPVEYIHKYAGR 177 + YHNH FEF+ + G+ FD ++ + +QVEMD CWV +AG DP+ YI KYAGR Sbjct: 124 LIFGYHNHAFEFEAEVDGQFVFDAMYSATTPEAVQVEMDVCWVQFAGQDPLTYIPKYAGR 183 Query: 178 LPIIHLKDMKKREDGSAETVVLGEGEVKLXXXXXXXXXXXXXXXXXXQDFCSRSPLESVA 237 LP++HLKD K +G+ +T+ L +G V L QD C PL+SV Sbjct: 184 LPLLHLKDFSKDAEGNMKTLELSQGSVNLPGVIQAASDAGTEWLIVEQDVCQNPPLQSVE 243 Query: 238 DSMKWIRA-YANQ 249 +SM W++ Y NQ Sbjct: 244 NSMNWLKQNYLNQ 256 >B1DJ61.1 B1DJ61_9BACL Xylose isomerase domain protein TIM barrel Length = 256 Score = 211 bits (538), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 114/251 (45%), Positives = 153/251 (60%), Gaps = 5/251 (1%) Query: 4 IGLQLYTLREELEQDFEGTIRKVAELGYAGVEFFHYFGRTAEQVNALLQETGLTALGAHR 63 IGLQ+YTLREE QDFEGT+RKVA +GY GVEF Y AEQ+ ALL E L A+G H Sbjct: 6 IGLQMYTLREETAQDFEGTLRKVAAMGYEGVEFAGYGDIPAEQMKALLDELNLVAIGNHV 65 Query: 64 PYDAMLNDTEQEISFNLSIGNRNLIVPYLTEEQRN---WEEVAVNLRKIGEQCSARGAVL 120 P + ++EI++ +IG + I P+L E R+ W++ V+ + G++ G V Sbjct: 66 PLVNLETKIDEEIAYLTTIGAKYAICPWLPVEVRDAEAWKKHIVDFAEYGKRFQEAGIVF 125 Query: 121 SYHNHDFEFKEQFGGRTAFDGIFEEVPADLLQVEMDTCWVYYAGYDPVEYIHKYAGRLPI 180 YHNH+FEF+ + G+ FD ++E V ADLLQVEMD WV YAG D +EYI KYAGRLP+ Sbjct: 126 CYHNHEFEFEVEIDGQVVFDKLYETVGADLLQVEMDLGWVQYAGRDVLEYISKYAGRLPL 185 Query: 181 IHLKD-MKKREDGSAETVVLGEGEVKLXXXXXXXXXXXXXXXXXXQDFCSRSPLESVADS 239 +HLKD +K E +TV LG G++ L QD C+ PL+SV +S Sbjct: 186 VHLKDFVKNTEKAEIDTVELGRGDLDLLPLIKQSEQANVKWLIVEQDRCANPPLQSVEES 245 Query: 240 MKWIRA-YANQ 249 + W++ Y NQ Sbjct: 246 INWLKTNYLNQ 256 >B0K7A8.1 B0K7A8_THEP3 Xylose isomerase domain protein TIM barrel Length = 249 Score = 179 bits (453), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 96/244 (39%), Positives = 139/244 (56%), Gaps = 5/244 (2%) Query: 2 LKIGLQLYTLREELEQDFEGTIRKVAELGYAGVEFFHYFGRTAEQVNALLQETGLTALGA 61 + I LQLYTLREE ++DF GT+ KVAE+GY GVEF Y G A ++ L + GL A G+ Sbjct: 3 IPIALQLYTLREETQKDFTGTLEKVAEIGYEGVEFAGYGGLKASELRKTLDKLGLKAAGS 62 Query: 62 HRPYDAMLNDTEQEISFNLSIGNRNLIVPYLTEEQR-NWEEVAVNLRKIGEQCSARGAVL 120 H D + N+ E+ I +NL IGN+ ++ P+ + R ++ E A KIGE+C +G Sbjct: 63 HVGIDLLKNNLEEVIDYNLEIGNKYIVCPWNEYKSREDYIETAKLFNKIGEKCREKGLEF 122 Query: 121 SYHNHDFEFKEQFGGRTAFDGIFEEVPADLLQVEMDTCWVYYAGYDPVEYIHKYAGRLPI 180 YHNH+ EF E + G D +++ +L++ E+D WV YAG DP+EY+ K++ RLP+ Sbjct: 123 CYHNHNHEF-EIYDGEYGLDILYKNTDKELVKAEIDAYWVTYAGVDPLEYLKKFSNRLPL 181 Query: 181 IHLKDMKKREDGSAETVVLGEGEVKLXXXXXXXXXXXXXXXXXXQDFCSRSPLESVADSM 240 IHLKDM K + E +G G + QD C R P+ESV S Sbjct: 182 IHLKDMDKEDRSFTE---IGNGIINFKEVIKITKENGVKWLIVEQDECKRPPIESVKISF 238 Query: 241 KWIR 244 + ++ Sbjct: 239 ENLK 242 >Q8R8P6.1 Q8R8P6_THETN Sugar phosphate isomerases/epimerases Length = 248 Score = 178 bits (452), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 97/247 (39%), Positives = 143/247 (57%), Gaps = 9/247 (3%) Query: 1 MLKIGLQLYTLREELEQDFEGTIRKVAELGYAGVEFFHYFGRTAEQVNALLQETGLTALG 60 ML I LQLYT+REE ++DF GT+ KVAE+GY GVEF Y G A ++ +L TGL A G Sbjct: 1 MLPIALQLYTVREEAQKDFTGTLEKVAEMGYEGVEFAGYGGLKASELKKVLDRTGLKAAG 60 Query: 61 AHRPYDAMLNDTEQEISFNLSIGNRNLI---VPYLTEEQRNWEEVAVNLRKIGEQCSARG 117 +H + + D + ++L IGNR ++ VPY ++E ++ E+A ++GE+C +G Sbjct: 61 SHVGIELLKKDLNGVLEYSLEIGNRYIVCPGVPYKSKE--DYIEMAKFFNEVGERCKEKG 118 Query: 118 AVLSYHNHDFEFKEQFGGRTAFDGIFEEVPADLLQVEMDTCWVYYAGYDPVEYIHKYAGR 177 + YHNH EF E + G D +F+ + ++ E+D WV YAG DP+EY+ K++GR Sbjct: 119 LIFCYHNHAHEF-EIYDGEYGLDILFKNTDKESVKAEIDVYWVKYAGVDPLEYLKKFSGR 177 Query: 178 LPIIHLKDMKKREDGSAETVVLGEGEVKLXXXXXXXXXXXXXXXXXXQDFCSRSPLESVA 237 LP+IHLKDM ++ + E +G G + QD C RSPLES Sbjct: 178 LPLIHLKDMDGKDRSNTE---IGNGIIDFKKIVKVAEENGVEWLIVEQDECKRSPLESAK 234 Query: 238 DSMKWIR 244 S++ +R Sbjct: 235 ISLENLR 241 >B7R6U3.1 B7R6U3_9THEO AP endonuclease, family 2 Length = 248 Score = 178 bits (452), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 97/247 (39%), Positives = 143/247 (57%), Gaps = 9/247 (3%) Query: 1 MLKIGLQLYTLREELEQDFEGTIRKVAELGYAGVEFFHYFGRTAEQVNALLQETGLTALG 60 ML I LQLYT+REE ++DF GT+ KVAE+GY GVEF Y G A ++ +L TGL A G Sbjct: 1 MLPIALQLYTVREEAQKDFTGTLEKVAEMGYEGVEFAGYGGLKASELKKVLDRTGLKAAG 60 Query: 61 AHRPYDAMLNDTEQEISFNLSIGNRNLI---VPYLTEEQRNWEEVAVNLRKIGEQCSARG 117 +H + + D + ++L IGNR ++ VPY ++E ++ E+A ++GE+C +G Sbjct: 61 SHVGIELLKKDLNGVLEYSLEIGNRYIVCPGVPYKSKE--DYIEMAKFFNEVGERCKEKG 118 Query: 118 AVLSYHNHDFEFKEQFGGRTAFDGIFEEVPADLLQVEMDTCWVYYAGYDPVEYIHKYAGR 177 + YHNH EF E + G D +F+ + ++ E+D WV YAG DP+EY+ K++GR Sbjct: 119 LIFCYHNHAHEF-EIYDGEYGLDILFKNTDKESVKAEIDVYWVKYAGVDPLEYLKKFSGR 177 Query: 178 LPIIHLKDMKKREDGSAETVVLGEGEVKLXXXXXXXXXXXXXXXXXXQDFCSRSPLESVA 237 LP+IHLKDM ++ + E +G G + QD C RSPLES Sbjct: 178 LPLIHLKDMDGKDRSNTE---IGNGIIDFKKIVKVAEENGVEWLIVEQDECKRSPLESAK 234 Query: 238 DSMKWIR 244 S++ +R Sbjct: 235 ISLENLR 241 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.137 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,450,594,884 Number of extensions: 55903835 Number of successful extensions: 120609 Number of sequences better than 1.0e-05: 213 Number of HSP's gapped: 120302 Number of HSP's successfully gapped: 213 Length of query: 255 Length of database: 3,060,696,203 Length adjustment: 133 Effective length of query: 122 Effective length of database: 1,807,701,208 Effective search space: 220539547376 Effective search space used: 220539547376 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 129 (54.3 bits)