BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0217.0007.p (210 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C1TX04.1 C1TX04_9SPHI Penicillin-binding protein, beta-lactamase... 239 1e-61 C4D7V3.1 C4D7V3_9SPHI Penicillin-binding protein, beta-lactamase... 237 5e-61 A9AUR5.1 A9AUR5_HERA2 Beta-lactamase 232 1e-59 B3K3X9.1 B3K3X9_9BACI Beta-lactamase 228 3e-58 B4D7B1.1 B4D7B1_9BACT Beta-lactamase 228 3e-58 >C1TX04.1 C1TX04_9SPHI Penicillin-binding protein, beta-lactamase class C Length = 530 Score = 239 bits (610), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 116/187 (62%), Positives = 139/187 (74%) Query: 11 LPRSLPEAQGISSAAISAFLKHMEKQRLGLHSFMLLRHGAVVAEAWWSPYRPELPHSLYS 70 LPRS P AQG+S+ I F +E RL LHS M+LR G VVAE WW+PY P+L H+LYS Sbjct: 39 LPRSSPGAQGMSAKGILDFANAVETDRLNLHSLMVLRQGKVVAEGWWAPYAPDLKHTLYS 98 Query: 71 LSKSFTSTAIGLAVAEGLLTVEDKVVSFFPEDAPADISPNLANMNISHLLMMGTGHTEDT 130 LSKSFTS+AIG AVAEG L V+DKVVSFFP++ PA +S NLA M + LL M TGH +DT Sbjct: 99 LSKSFTSSAIGFAVAEGKLKVDDKVVSFFPDEKPATVSANLAAMRVRDLLSMSTGHDKDT 158 Query: 131 TSFMENSEDGNWVKAFLQLPVGKTPGTHFLYNTGATYMLSAILQKVSGLTLLEYLEPRLF 190 T + S NWVK+FL PV PGT F+YN+GATYMLSAI+QK++G TLLEYL+PRLF Sbjct: 159 TGKLRESGSDNWVKSFLAQPVEHEPGTFFVYNSGATYMLSAIIQKLTGQTLLEYLKPRLF 218 Query: 191 APLGIHN 197 PL I + Sbjct: 219 QPLVIED 225 >C4D7V3.1 C4D7V3_9SPHI Penicillin-binding protein, beta-lactamase class C Length = 530 Score = 237 bits (605), Expect = 5e-61, Method: Compositional matrix adjust. Identities = 112/190 (58%), Positives = 141/190 (74%) Query: 8 TRPLPRSLPEAQGISSAAISAFLKHMEKQRLGLHSFMLLRHGAVVAEAWWSPYRPELPHS 67 T L RSLPEAQG++ + F+ +E +L +HS M+LRHG VVAE WW+PY P+L H+ Sbjct: 36 TGKLARSLPEAQGVAPGGLLDFVNTIEANKLNVHSMMVLRHGHVVAEGWWAPYAPQLKHT 95 Query: 68 LYSLSKSFTSTAIGLAVAEGLLTVEDKVVSFFPEDAPADISPNLANMNISHLLMMGTGHT 127 LYSLSKSFTSTA+G+AVAE LTVEDKVVSFFP + PA +S NLA M + LL M TGH Sbjct: 96 LYSLSKSFTSTAVGMAVAEKRLTVEDKVVSFFPNELPATVSDNLAAMRVKDLLTMSTGHD 155 Query: 128 EDTTSFMENSEDGNWVKAFLQLPVGKTPGTHFLYNTGATYMLSAILQKVSGLTLLEYLEP 187 +D+T + + NW+KAFL PV PGT F+YN+GATYMLSAI+QK++G ++EYL+P Sbjct: 156 KDSTPALREGGNTNWIKAFLAQPVEHKPGTFFVYNSGATYMLSAIVQKLTGQPVVEYLKP 215 Query: 188 RLFAPLGIHN 197 RLF PLGI Sbjct: 216 RLFGPLGIEG 225 >A9AUR5.1 A9AUR5_HERA2 Beta-lactamase Length = 486 Score = 232 bits (592), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 110/187 (58%), Positives = 138/187 (73%) Query: 11 LPRSLPEAQGISSAAISAFLKHMEKQRLGLHSFMLLRHGAVVAEAWWSPYRPELPHSLYS 70 LPR+ PEAQGI+SAA+ F++ M+ +HS MLLRHG VVAEAWWSPY P P L+S Sbjct: 9 LPRATPEAQGIASAALLQFIEAMDTHVNQIHSLMLLRHGHVVAEAWWSPYAPAYPQLLFS 68 Query: 71 LSKSFTSTAIGLAVAEGLLTVEDKVVSFFPEDAPADISPNLANMNISHLLMMGTGHTEDT 130 LSKSFT+TA+GLA+AEG ++D V+SFFPE PA+ SP LA M + LL M TGH +D Sbjct: 69 LSKSFTATAVGLAIAEGYFAIDDPVISFFPEHTPAECSPMLAAMRVRDLLSMATGHADDP 128 Query: 131 TSFMENSEDGNWVKAFLQLPVGKTPGTHFLYNTGATYMLSAILQKVSGLTLLEYLEPRLF 190 M + +DGNW+K FL+ PV PGTHF+YNT ATYMLSAI+Q+ + + L EYL+PRLF Sbjct: 129 WVSMISRQDGNWIKGFLETPVVYAPGTHFVYNTSATYMLSAIVQQTTTIRLDEYLKPRLF 188 Query: 191 APLGIHN 197 PLGI + Sbjct: 189 EPLGIEH 195 >B3K3X9.1 B3K3X9_9BACI Beta-lactamase Length = 477 Score = 228 bits (581), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 112/197 (56%), Positives = 138/197 (70%), Gaps = 5/197 (2%) Query: 3 MENLITRPLPRSLPEAQGISSAAISAFLKHMEKQRLGLHSFMLLRHGAVVAEAWWSPYRP 62 M R LPRS PE QGISS +I F+ ++++ L LHSFML+RHG VAE WW PY Sbjct: 1 MNTNTVRLLPRSTPENQGISSQSIKRFIGSIQEKELELHSFMLVRHGHSVAEGWWKPYDA 60 Query: 63 ELPHSLYSLSKSFTSTAIGLAVAEGLLTVEDKVVSFFPEDAPADISPNLANMNISHLLMM 122 + PH L+SLSKSFTSTAIGL V EG +T+ED+V+ FFPE+ P D SPNL+ M I LL+M Sbjct: 61 DKPHMLFSLSKSFTSTAIGLLVQEGRITLEDRVIGFFPENKPEDPSPNLSAMTIRDLLIM 120 Query: 123 GTGHTEDTTSFMENSEDGNWVKAFLQLPVGKTPGTHFLYNTGATYMLSAILQKVSGLTLL 182 GTGH ++ + WV F + V PGTHF+YN+ ATYMLSAILQKV+G+TLL Sbjct: 121 GTGHAQEPA-----IQSDIWVDDFFKQAVEHEPGTHFVYNSAATYMLSAILQKVTGITLL 175 Query: 183 EYLEPRLFAPLGIHNPA 199 +YL+PRLF PLGI A Sbjct: 176 DYLQPRLFEPLGIQGAA 192 >B4D7B1.1 B4D7B1_9BACT Beta-lactamase Length = 526 Score = 228 bits (581), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 107/190 (56%), Positives = 136/190 (71%), Gaps = 2/190 (1%) Query: 8 TRPLPRSLPEAQGISSAAISAFLKHMEKQRLGLHSFMLLRHGAVVAEAWWSPYRPELPHS 67 TR LPRS PEA+G+++A I AFL + + + HSFM+ RHG ++AE WW PY ELPH+ Sbjct: 33 TRELPRSTPEAEGVATAGIEAFLDALAQSKHEFHSFMMARHGKIIAEGWWKPYAAELPHT 92 Query: 68 LYSLSKSFTSTAIGLAVAEGLLTVEDKVVSFFPEDAPADISPNLANMNISHLLMMGTGHT 127 +YS+SKSFTSTA+GLAVAEG LTVEDKV SFFP+D P +IS NLA + + HLL M G Sbjct: 93 MYSMSKSFTSTAVGLAVAEGKLTVEDKVTSFFPDDLPKEISENLAALQVKHLLTMSVGSE 152 Query: 128 EDTTSFMENSEDGNWVKAFLQLPVGKTPGTHFLYNTGATYMLSAILQKVSGLTLLEYLEP 187 + T M E NWV+AFL P+ PG+ FLYN+ ATYM SAI+Q V+G +++YL P Sbjct: 153 HEPTHDMVEQE--NWVRAFLAAPISHAPGSVFLYNSAATYMCSAIVQTVTGQKVIDYLTP 210 Query: 188 RLFAPLGIHN 197 +LF PLGI Sbjct: 211 KLFTPLGIEG 220 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.133 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,264,133,355 Number of extensions: 51227759 Number of successful extensions: 118713 Number of sequences better than 1.0e-05: 453 Number of HSP's gapped: 119277 Number of HSP's successfully gapped: 453 Length of query: 210 Length of database: 3,060,696,203 Length adjustment: 130 Effective length of query: 80 Effective length of database: 1,835,964,253 Effective search space: 146877140240 Effective search space used: 146877140240 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 128 (53.9 bits)