BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0217.0003.p (237 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C0GBZ3.1 C0GBZ3_9FIRM Two component transcriptional regulator, w... 203 1e-50 Q5WGY5.1 Q5WGY5_BACSK Two-component response regulator 203 1e-50 A3DEZ1.1 A3DEZ1_CLOTH Two component transcriptional regulator, w... 203 1e-50 A4J5S1.1 A4J5S1_DESRM Two component transcriptional regulator, w... 202 3e-50 B8FRJ5.1 B8FRJ5_DESHD Two component transcriptional regulator, w... 199 1e-49 >C0GBZ3.1 C0GBZ3_9FIRM Two component transcriptional regulator, winged helix family Length = 231 Score = 203 bits (516), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 104/235 (44%), Positives = 152/235 (64%), Gaps = 8/235 (3%) Query: 2 GTIVVVDDDLFILQLLSEYLRKEAYEVTSFSSGANLVEYVRSEEPECLILDIMMPGIDGL 61 G I++VDD+ I +L+ YL KE + V + G V+ +S P+ +ILD+M+P +DG Sbjct: 4 GLILIVDDEEHIRELVRLYLEKEGFTVALAADGEEAVQKAKSTTPQLIILDLMLPKLDGW 63 Query: 62 SLLTELRSFTEIPIIMISARGEESDRIHGLELGCSDFLSKPFNPRELVGRVKAMLRLYRM 121 + E+R F+E+PIIM++A+GEE D++ GLELG D+L+KPF+PRELV RVKA+LR R Sbjct: 64 DVCREVRKFSEVPIIMLTAKGEEFDKVLGLELGADDYLTKPFSPRELVARVKAILR--RA 121 Query: 122 GNGASGDSAAPIKPDHICHAGNLKIYADYRRVTVDGTDISLTSREFELLLFLASHIERPF 181 D+ D + G L I R V VD +++LT +EF+LL FLA+H + F Sbjct: 122 TPEEQTDTE-----DVLTFPG-LAINHSSREVHVDDREVTLTPKEFDLLWFLATHPGKVF 175 Query: 182 GREQLIQHVWNYDFFGDVRVVDDLVKRIRKKLAEHGSTLLINTVWGFGYKAAVSK 236 REQL+ VW YD++GD+R VD +KR+R+K+ G+T + T+WG GYK V + Sbjct: 176 TREQLLTAVWGYDYYGDLRTVDTHIKRLREKVERDGNTPHVKTIWGVGYKFEVQE 230 >Q5WGY5.1 Q5WGY5_BACSK Two-component response regulator Length = 238 Score = 203 bits (516), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 102/236 (43%), Positives = 154/236 (65%), Gaps = 6/236 (2%) Query: 3 TIVVVDDDLFILQLLSEYLRKEAYEVTSFSSGANLVEYVRSEEPECLILDIMMPGIDGLS 62 T++VVDD+ I +LL YL +E Y++ S+G +E ++E + ++LD+MMPG+DG+ Sbjct: 6 TLLVVDDEERIRRLLRMYLEREEYQIEEASNGEEALELALAKEYDLILLDVMMPGMDGVE 65 Query: 63 LLTELRSFTEIPIIMISARGEESDRIHGLELGCSDFLSKPFNPRELVGRVKAMLRLYRMG 122 + ELR P++M++A+GEE++R+ G E+G D++ KPF+PRE+V RVKA+LR Sbjct: 66 MCQELRKKKATPVMMLTAKGEEANRVQGFEVGADDYIVKPFSPREVVLRVKALLRRASAT 125 Query: 123 NGASGDSAAPIKPDHICHAGNLKIYADYRRVTVDGTDISLTSREFELLLFLASHIERPFG 182 D+ + + G L I D RVTVD T+ISLT +E+ELL +LA ++ F Sbjct: 126 KFLQTDT----QTKDVLVFGPLTIDNDAHRVTVDKTEISLTPKEYELLFYLAQSPDKVFS 181 Query: 183 REQLIQHVWNYDFFGDVRVVDDLVKRIRKKLAEHGSTL--LINTVWGFGYKAAVSK 236 REQL++ VWNY+FFGD+R VD VKR+R+KL + +I+TVWG GYK ++ Sbjct: 182 REQLLKDVWNYEFFGDLRTVDTHVKRLREKLNRVSPEVAAIISTVWGVGYKFEATR 237 >A3DEZ1.1 A3DEZ1_CLOTH Two component transcriptional regulator, winged helix family Length = 228 Score = 203 bits (516), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 101/232 (43%), Positives = 144/232 (62%), Gaps = 10/232 (4%) Query: 4 IVVVDDDLFILQLLSEYLRKEAYEVTSFSSGANLVEYVRSEEPECLILDIMMPGIDGLSL 63 ++V+DDD+ I +L+ Y+ KE +EV + +G+ +E R+E P +ILDIM+PG DG + Sbjct: 7 VLVIDDDVNICELIRLYMEKEGFEVVTVYNGSKALEVFRNEAPNIVILDIMLPGADGWQV 66 Query: 64 LTELRSFTEIPIIMISARGEESDRIHGLELGCSDFLSKPFNPRELVGRVKAMLRLYRMGN 123 E+R + IP+IM+SA+GE D++ GLELG D+L KPF P+ELV RVKA+LR Y + Sbjct: 67 CREIRKISNIPVIMLSAKGETFDKVLGLELGADDYLVKPFEPKELVARVKAVLRRYEHKD 126 Query: 124 GASGDSAAPIKPDHICHAGNLKIYADYRRVTVDGTDISLTSREFELLLFLASHIERPFGR 183 D + P+ I + N + V+G ++ +E ELL FLAS+ + F R Sbjct: 127 ---SDVQEIVYPNLIINKTNYTL-------KVNGKEMEFPPKELELLYFLASNPNKVFTR 176 Query: 184 EQLIQHVWNYDFFGDVRVVDDLVKRIRKKLAEHGSTLLINTVWGFGYKAAVS 235 EQLI+ VW YDF+GD R VD +KR+R+KL G + TVWG GYK V Sbjct: 177 EQLIEQVWGYDFYGDSRTVDVHIKRLREKLDSEGQNWQLKTVWGVGYKFEVK 228 >A4J5S1.1 A4J5S1_DESRM Two component transcriptional regulator, winged helix family Length = 230 Score = 202 bits (513), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 104/233 (44%), Positives = 146/233 (62%), Gaps = 6/233 (2%) Query: 4 IVVVDDDLFILQLLSEYLRKEAYEVTSFSSGANLVEYVRSEEPECLILDIMMPGIDGLSL 63 +++VDD+ I L+ YL KE +EV +G +V+ ++S + ++LDIM+PG DGLSL Sbjct: 4 LLIVDDEEKIRNLIKVYLVKEGFEVDELDNGNRVVDSIKSSHFDMVVLDIMLPGPDGLSL 63 Query: 64 LTELRSFTEIPIIMISARGEESDRIHGLELGCSDFLSKPFNPRELVGRVKAMLRLYRMGN 123 E+R + IPIIM++A+G+E DRI GLE+G D++ KPF+PRELV R+ A+LR Sbjct: 64 CKEIRKISNIPIIMLTAKGDEIDRIIGLEVGADDYIVKPFSPRELVARINAILRRVAAQP 123 Query: 124 GASGDSAAPIKPDHICHAGNLKIYADYRRVTVDGTDISLTSREFELLLFLASHIERPFGR 183 D A I L I D R V V G++I+LT +EF+LL F+A R F R Sbjct: 124 IIQEDRTA------ILSFSELTINPDNRTVEVRGSEIALTPKEFDLLYFMAKTPGRAFSR 177 Query: 184 EQLIQHVWNYDFFGDVRVVDDLVKRIRKKLAEHGSTLLINTVWGFGYKAAVSK 236 E L+++VW YDF+GD+R VD + R+R KL G+ I TVWG GYK V+K Sbjct: 178 ENLLENVWGYDFYGDLRTVDTHINRLRDKLNMEGTKQAITTVWGVGYKFEVTK 230 >B8FRJ5.1 B8FRJ5_DESHD Two component transcriptional regulator, winged helix family Length = 230 Score = 199 bits (507), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 108/231 (46%), Positives = 144/231 (62%), Gaps = 9/231 (3%) Query: 1 VGTIVVVDDDLFILQLLSEYLRKEAYEVTSFSSGANLVEYVRSEEPECLILDIMMPGIDG 60 + I+V+DD+ I L+ YL +E YEV +G +E + ++ LI+D+MMP IDG Sbjct: 1 MNAILVIDDEERIRHLVRMYLEREGYEVDEAGNGREALEKFQKQDYALLIVDLMMPEIDG 60 Query: 61 LSLLTELRSFTEIPIIMISARGEESDRIHGLELGCSDFLSKPFNPRELVGRVKAMLRLYR 120 + ++R ++IPIIM++ARGEE DR+ G ELG D+L KPF+ +ELV RVKA+LR R Sbjct: 61 WKVCRDVRERSDIPIIMLTARGEEFDRVLGFELGADDYLVKPFSTKELVARVKALLRRSR 120 Query: 121 MGNGASGDSAAPIKPDHICHAGNLKIYADYRRVTVDGTDISLTSREFELLLFLASHIERP 180 GN A S P LKI D RV++D I T REFELL FLA + R Sbjct: 121 -GNTAISSSDLLFGP--------LKIEKDKHRVSIDDEQIPFTPREFELLYFLAKNPSRV 171 Query: 181 FGREQLIQHVWNYDFFGDVRVVDDLVKRIRKKLAEHGSTLLINTVWGFGYK 231 F REQL++ VW YDF+GD R VD VK+IR+KLA+ ++ TVWG GYK Sbjct: 172 FSREQLMETVWGYDFYGDARTVDTHVKKIREKLADPKVRSMLATVWGVGYK 222 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.323 0.141 0.413 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,379,041,939 Number of extensions: 55375720 Number of successful extensions: 223759 Number of sequences better than 1.0e-05: 28365 Number of HSP's gapped: 200387 Number of HSP's successfully gapped: 28490 Length of query: 237 Length of database: 3,060,696,203 Length adjustment: 132 Effective length of query: 105 Effective length of database: 1,817,122,223 Effective search space: 190797833415 Effective search space used: 190797833415 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 129 (54.3 bits)