BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0217.0001.p (423 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KCC1.1 B3KCC1_9BACI Peptidase M29 aminopeptidase II 659 0.0 C0ZCY0.1 C0ZCY0_BREBN Aminopeptidase AmpS EC=3.4.11.- 458 e-127 A4IPY1.1 A4IPY1_GEOTN Aminopeptidase II 454 e-125 B4BNL1.1 B4BNL1_9BACI Peptidase M29 aminopeptidase II 454 e-125 A0R928.1 A0R928_BACAH Aminopeptidase II. Metallo peptidase. MERO... 452 e-125 >B3KCC1.1 B3KCC1_9BACI Peptidase M29 aminopeptidase II Length = 409 Score = 659 bits (1701), Expect = 0.0, Method: Compositional matrix adjust. Identities = 315/409 (77%), Positives = 350/409 (85%) Query: 14 MLDFDVMLEKYADLVVRVGVNVQPGQVLMIHSPLETAELTRLIVGKAYEAGAKYVLVDWD 73 M +F+ LEKYA+LVV+VGVNVQPGQVL+I++P+ET ELTR IV KAY+AGAKYV VDW+ Sbjct: 1 MDNFEKNLEKYAELVVKVGVNVQPGQVLIINAPIETVELTRRIVAKAYDAGAKYVQVDWE 60 Query: 74 DEKVTRIRYEKAADDSFGYYPQWQADMLEGFAEEGGAILHIKVPDPELFRGIDXXXXXXX 133 DEK+TRIRYEKA +DSF YYPQWQAD ++ AE GGAIL IKVPDPELFRGID Sbjct: 61 DEKITRIRYEKAPEDSFHYYPQWQADAMQQLAEGGGAILRIKVPDPELFRGIDSVKVSTA 120 Query: 134 XXXXXXXXXXYQNYTRNNKISWSLIKAPTKAWADKVYAGLPEEERVAAMWEAVFQMNRVG 193 YQ Y RNNKISWSLIKAPT+AWA+KV+ LPEEER+ AMW+AVF MNRVG Sbjct: 121 VKAAAMANEKYQVYVRNNKISWSLIKAPTRAWANKVFPDLPEEERIQAMWDAVFLMNRVG 180 Query: 194 SGDPVAAWREHIADLKKSQDRMNAKRYKSLHYRAPGTDLHVELPEGHLWRGGGGENASGV 253 S DPVAAWR+HIA LK Q+ MNAKRYKS HYRAPGTDL V++PEG+LW GGG EN +GV Sbjct: 181 SEDPVAAWRDHIAGLKLRQNHMNAKRYKSFHYRAPGTDLRVDMPEGYLWLGGGDENEAGV 240 Query: 254 YFVANMPTEEVYTMPHRKGVNGTVSSTLPLNLNGRLVDGITITFTDGKVTAYDAESGREH 313 YFVANMPTEE+YTMPHR GVNGTVSSTLPLNLNGRLV+GI +TF DGKV AY+AESGREH Sbjct: 241 YFVANMPTEEIYTMPHRTGVNGTVSSTLPLNLNGRLVEGIKLTFKDGKVIAYEAESGREH 300 Query: 314 LTSLLETDEGASYLGEVALVPHDSPISRLNTVFYNTGIDENASCHFALGSAYPSNIEGGT 373 LT+LLETDEGASYLGE+ALVPHDSPIS+LN VFYNTGIDENASCHFALGSAYP NIEGGT Sbjct: 301 LTTLLETDEGASYLGEMALVPHDSPISQLNRVFYNTGIDENASCHFALGSAYPVNIEGGT 360 Query: 374 SLSSEELLERGANVSLTHVDFMVGSAELDIDGELADGTVEPVFRKGNWV 422 +S EELL RGANVSLTHVDFM+GSAELDIDG LADGT+EPVFR G WV Sbjct: 361 KMSKEELLARGANVSLTHVDFMIGSAELDIDGVLADGTIEPVFRGGRWV 409 >C0ZCY0.1 C0ZCY0_BREBN Aminopeptidase AmpS EC=3.4.11.- Length = 408 Score = 458 bits (1179), Expect = e-127, Method: Compositional matrix adjust. Identities = 210/407 (51%), Positives = 287/407 (70%) Query: 15 LDFDVMLEKYADLVVRVGVNVQPGQVLMIHSPLETAELTRLIVGKAYEAGAKYVLVDWDD 74 + F+++ ++YADL V+VGVNVQP Q L++ +PL TA R + KAYEAGAK+V +DW D Sbjct: 1 MSFEILFDRYADLAVKVGVNVQPMQTLVVTAPLSTAPFVRKVAKKAYEAGAKHVHIDWTD 60 Query: 75 EKVTRIRYEKAADDSFGYYPQWQADMLEGFAEEGGAILHIKVPDPELFRGIDXXXXXXXX 134 +++TR++Y+ A D++F YPQW+ LE AE G A L+I +P+L +G++ Sbjct: 61 DELTRMKYDLAPDEAFREYPQWKVQGLEEMAENGAAFLYISAANPDLLKGVNLDRISTAN 120 Query: 135 XXXXXXXXXYQNYTRNNKISWSLIKAPTKAWADKVYAGLPEEERVAAMWEAVFQMNRVGS 194 +++YT ++K+SW ++ P+ AWA V+ LP+EE+ A+W+A+F+ R Sbjct: 121 KTAGQALHKFRSYTMSDKVSWCVLAVPSPAWAAMVFPHLPQEEQEPALWDAIFRATRADM 180 Query: 195 GDPVAAWREHIADLKKSQDRMNAKRYKSLHYRAPGTDLHVELPEGHLWRGGGGENASGVY 254 DPV AW +H A L D++NAK+Y+ LHY APGT+L +ELP H+W GGGG N GV Sbjct: 181 DDPVQAWHDHHAILNSKVDQLNAKQYRYLHYEAPGTNLTIELPANHIWIGGGGVNKDGVS 240 Query: 255 FVANMPTEEVYTMPHRKGVNGTVSSTLPLNLNGRLVDGITITFTDGKVTAYDAESGREHL 314 F+ANMPTEEV+T P ++GVNGTV ST PL+ +G L++ T+TF G++ + AE G E L Sbjct: 241 FMANMPTEEVFTAPLKEGVNGTVRSTKPLSYHGNLIENFTLTFEKGRIVSATAEKGEESL 300 Query: 315 TSLLETDEGASYLGEVALVPHDSPISRLNTVFYNTGIDENASCHFALGSAYPSNIEGGTS 374 L+ETDEG+ YLGEVALVPH SPIS+ N +FYNT DENAS H A+G+AY NIEGG Sbjct: 301 KQLIETDEGSHYLGEVALVPHLSPISQSNIIFYNTLFDENASNHLAIGNAYSVNIEGGAD 360 Query: 375 LSSEELLERGANVSLTHVDFMVGSAELDIDGELADGTVEPVFRKGNW 421 +S+EEL RG N+SLTHVDFM+GSAE++IDGE ADG EP+FR GNW Sbjct: 361 MSNEELASRGINISLTHVDFMIGSAEMNIDGETADGKREPLFRNGNW 407 >A4IPY1.1 A4IPY1_GEOTN Aminopeptidase II Length = 413 Score = 454 bits (1167), Expect = e-125, Method: Compositional matrix adjust. Identities = 214/403 (53%), Positives = 273/403 (67%) Query: 21 LEKYADLVVRVGVNVQPGQVLMIHSPLETAELTRLIVGKAYEAGAKYVLVDWDDEKVTRI 80 L KYA+L V+VGVNVQPGQ L + +PL+ A L R I AYE GAK+V VDWDDE +T I Sbjct: 8 LNKYAELAVKVGVNVQPGQTLFVSAPLDAAPLVRKIAKTAYETGAKHVHVDWDDESLTYI 67 Query: 81 RYEKAADDSFGYYPQWQADMLEGFAEEGGAILHIKVPDPELFRGIDXXXXXXXXXXXXXX 140 +++ A ++SF YP W+A +E E+G A L I P+P+L + +D Sbjct: 68 KFQHAPEESFSEYPMWRAKAMEELVEQGAAFLSIYAPNPDLLKDVDPKRIATANKTAAQA 127 Query: 141 XXXYQNYTRNNKISWSLIKAPTKAWADKVYAGLPEEERVAAMWEAVFQMNRVGSGDPVAA 200 +QN ++ WS+I PT AWA KV++ L +EE + +WE +F++ RV DP+AA Sbjct: 128 LINFQNAMMTDRNCWSIISVPTAAWAQKVFSDLSQEEAINQLWETIFRIVRVDQDDPIAA 187 Query: 201 WREHIADLKKSQDRMNAKRYKSLHYRAPGTDLHVELPEGHLWRGGGGENASGVYFVANMP 260 WR+H L + D +N K+YK L Y APGT+L VEL +GH+W GG + SGV F NMP Sbjct: 188 WRKHNDRLGRIVDYLNNKQYKQLVYEAPGTNLTVELVDGHVWHGGASTSQSGVRFNPNMP 247 Query: 261 TEEVYTMPHRKGVNGTVSSTLPLNLNGRLVDGITITFTDGKVTAYDAESGREHLTSLLET 320 TEEVYTMPH+ GVNGTV +T PLN +G ++DG T+TF DG+V + AE G E L LL+T Sbjct: 248 TEEVYTMPHKDGVNGTVRNTKPLNYDGNVIDGFTLTFKDGQVVDFSAEEGYETLKHLLDT 307 Query: 321 DEGASYLGEVALVPHDSPISRLNTVFYNTGIDENASCHFALGSAYPSNIEGGTSLSSEEL 380 D+GA LGEVALVPH SP+S N +FYNT DENA+CHFALG AYP+NIE G +LS+EEL Sbjct: 308 DDGARRLGEVALVPHQSPVSLSNLIFYNTLFDENAACHFALGKAYPTNIENGAALSNEEL 367 Query: 381 LERGANVSLTHVDFMVGSAELDIDGELADGTVEPVFRKGNWVL 423 RG N SL HVDFM+GSAEL+IDG DG EP+FR GNW Sbjct: 368 GRRGVNDSLVHVDFMIGSAELNIDGVTKDGKREPIFRSGNWAF 410 >B4BNL1.1 B4BNL1_9BACI Peptidase M29 aminopeptidase II Length = 413 Score = 454 bits (1167), Expect = e-125, Method: Compositional matrix adjust. Identities = 214/403 (53%), Positives = 273/403 (67%) Query: 21 LEKYADLVVRVGVNVQPGQVLMIHSPLETAELTRLIVGKAYEAGAKYVLVDWDDEKVTRI 80 L KYA+L V+VGVNVQPGQ L + +PL+ A L R I AYE GAK+V VDWDDE +T I Sbjct: 8 LNKYAELAVKVGVNVQPGQTLFVSAPLDAAPLVRKIAKTAYETGAKHVHVDWDDESLTYI 67 Query: 81 RYEKAADDSFGYYPQWQADMLEGFAEEGGAILHIKVPDPELFRGIDXXXXXXXXXXXXXX 140 +++ A ++SF YP W+A +E E+G A L I P+P+L + +D Sbjct: 68 KFQHAPEESFSEYPMWRAKAMEELVEQGAAFLSIYAPNPDLLKDVDPKRIATANKTAAQA 127 Query: 141 XXXYQNYTRNNKISWSLIKAPTKAWADKVYAGLPEEERVAAMWEAVFQMNRVGSGDPVAA 200 +QN ++ WS+I PT AWA KV++ L +EE + +WE +F++ RV DP+AA Sbjct: 128 LINFQNAMMTDRNCWSIISVPTAAWAQKVFSDLSQEEAINQLWETIFRIVRVDQDDPIAA 187 Query: 201 WREHIADLKKSQDRMNAKRYKSLHYRAPGTDLHVELPEGHLWRGGGGENASGVYFVANMP 260 WR+H L + D +N K+YK L Y APGT+L VEL +GH+W GG + SGV F NMP Sbjct: 188 WRKHNDRLGRIVDYLNNKQYKQLVYEAPGTNLTVELVDGHVWHGGASTSQSGVRFNPNMP 247 Query: 261 TEEVYTMPHRKGVNGTVSSTLPLNLNGRLVDGITITFTDGKVTAYDAESGREHLTSLLET 320 TEEVYTMPH+ GVNGTV +T PLN +G ++DG T+TF DG+V + AE G E L LL+T Sbjct: 248 TEEVYTMPHKDGVNGTVRNTKPLNYDGNVIDGFTLTFKDGQVVDFSAEEGYETLKHLLDT 307 Query: 321 DEGASYLGEVALVPHDSPISRLNTVFYNTGIDENASCHFALGSAYPSNIEGGTSLSSEEL 380 D+GA LGEVALVPH SP+S N +FYNT DENA+CHFALG AYP+NIE G +LS+EEL Sbjct: 308 DDGARRLGEVALVPHQSPVSLSNLIFYNTLFDENAACHFALGKAYPTNIENGAALSNEEL 367 Query: 381 LERGANVSLTHVDFMVGSAELDIDGELADGTVEPVFRKGNWVL 423 RG N SL HVDFM+GSAEL+IDG DG EP+FR GNW Sbjct: 368 GRRGVNDSLVHVDFMIGSAELNIDGVTKDGKREPIFRSGNWAF 410 >A0R928.1 A0R928_BACAH Aminopeptidase II. Metallo peptidase. MEROPS family M29 Length = 447 Score = 452 bits (1162), Expect = e-125, Method: Compositional matrix adjust. Identities = 209/409 (51%), Positives = 275/409 (67%) Query: 15 LDFDVMLEKYADLVVRVGVNVQPGQVLMIHSPLETAELTRLIVGKAYEAGAKYVLVDWDD 74 + F+ LEKYA L V VGVN+QPGQ L I +PLE + RL+ KAY++GAK+V VDW+D Sbjct: 39 MSFEQTLEKYAALAVNVGVNIQPGQTLSISAPLEAVQFVRLVTEKAYKSGAKHVYVDWND 98 Query: 75 EKVTRIRYEKAADDSFGYYPQWQADMLEGFAEEGGAILHIKVPDPELFRGIDXXXXXXXX 134 E +TR++++ A +++F +P W+A+ E A+EG A + I +P+L +G+D Sbjct: 99 ETLTRLKFDLAPEEAFAEFPSWKANAREELAKEGAAFMSIYAENPDLLKGVDSTRIATAH 158 Query: 135 XXXXXXXXXYQNYTRNNKISWSLIKAPTKAWADKVYAGLPEEERVAAMWEAVFQMNRVGS 194 Y++Y + +K+SW +I PTK WA KV+ EE+ A +W+A+F+ R Sbjct: 159 KVAGEAMKVYRDYVQADKVSWCVISVPTKEWAAKVFPDAAPEEQEAKLWDAIFKATRADL 218 Query: 195 GDPVAAWREHIADLKKSQDRMNAKRYKSLHYRAPGTDLHVELPEGHLWRGGGGENASGVY 254 +PV AW+EH L D +N K YK+LHY PGTDL +ELPE H+W G G N V Sbjct: 219 ENPVEAWKEHDKTLHTKVDYLNEKHYKALHYTGPGTDLTIELPEKHVWAGAGSLNEKNVP 278 Query: 255 FVANMPTEEVYTMPHRKGVNGTVSSTLPLNLNGRLVDGITITFTDGKVTAYDAESGREHL 314 F+AN+PTEEV+TMP + GVNG VSST PL G ++D T+TF +G++ Y AE G E L Sbjct: 279 FMANIPTEEVFTMPLKTGVNGQVSSTKPLAFAGNIIDNFTLTFENGRIVDYKAEVGEEAL 338 Query: 315 TSLLETDEGASYLGEVALVPHDSPISRLNTVFYNTGIDENASCHFALGSAYPSNIEGGTS 374 L+ETDEG+ +LGEVALVPHDSPIS N +FYNT DENASCH A+GSAY N+ GG + Sbjct: 339 KHLVETDEGSHFLGEVALVPHDSPISNTNILFYNTLFDENASCHLAIGSAYAFNLVGGKT 398 Query: 375 LSSEELLERGANVSLTHVDFMVGSAELDIDGELADGTVEPVFRKGNWVL 423 +S EEL E GAN S+TH DFM+GSAELDIDG ADG EP+FRKGNW Sbjct: 399 MSKEELAENGANTSITHNDFMIGSAELDIDGITADGRHEPIFRKGNWAF 447 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.315 0.134 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,718,377,828 Number of extensions: 116784087 Number of successful extensions: 265236 Number of sequences better than 1.0e-05: 617 Number of HSP's gapped: 264372 Number of HSP's successfully gapped: 617 Length of query: 423 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 285 Effective length of database: 1,760,596,133 Effective search space: 501769897905 Effective search space used: 501769897905 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 133 (55.8 bits)