BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0214.0001.p (161 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1D8X9.1 B1D8X9_9BACL Phosphoribosylaminoimidazole carboxylase, ... 261 1e-68 Q9KF63.1 Q9KF63_BACHD Phosphoribosylaminoimidazole carboxylase I 259 6e-68 Q65MT4.1 Q65MT4_BACLD PurE 253 3e-66 B4AI89.1 B4AI89_BACPU Phosphoribosylaminoimidazole carboxylase, ... 253 4e-66 A8FAM1.1 A8FAM1_BACP2 Phosphoribosylaminoimidazole carboxylase c... 252 1e-65 >B1D8X9.1 B1D8X9_9BACL Phosphoribosylaminoimidazole carboxylase, catalytic subunit EC=4.1.1.21 Length = 214 Score = 261 bits (667), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 129/161 (80%), Positives = 146/161 (90%) Query: 1 MSVQVGVIMGSKSDWETMEHACIVLEELGVAYEKKVISAHRTPDLMFRYAEEAAGRGLRV 60 MS +VGVIMGSKSDW+TM+ AC VLEEL + YEKKV+SAHRTPDLMF YAE AA RGL+V Sbjct: 54 MSAKVGVIMGSKSDWDTMKLACDVLEELQIPYEKKVVSAHRTPDLMFEYAETAAERGLKV 113 Query: 61 IIAGAGGAAHLPGMVAAKTMLPVIGVPVQSKALNGLDSLLSIVQMPGGIPVATVAIGRAG 120 IIAGAGGAAHLPGMVAAKT+LPVIGVPV+S L+GLDSLLSIVQMPGGIPVATVAIG AG Sbjct: 114 IIAGAGGAAHLPGMVAAKTILPVIGVPVKSSNLSGLDSLLSIVQMPGGIPVATVAIGNAG 173 Query: 121 ATNAGLLAAQIIGAFDPEVQSRAQQRRDAIQREVLESSESL 161 TNAGLLAAQ++GAFDPEVQ+R + RR+ I++EVLESSE+L Sbjct: 174 GTNAGLLAAQMLGAFDPEVQARVEARRERIKQEVLESSETL 214 >Q9KF63.1 Q9KF63_BACHD Phosphoribosylaminoimidazole carboxylase I Length = 161 Score = 259 bits (661), Expect = 6e-68, Method: Compositional matrix adjust. Identities = 127/157 (80%), Positives = 143/157 (91%) Query: 5 VGVIMGSKSDWETMEHACIVLEELGVAYEKKVISAHRTPDLMFRYAEEAAGRGLRVIIAG 64 VGVIMGS SDWETM+HAC +LEEL V YEKKV+SAHRTPDLMF+YAE A RGL+VIIAG Sbjct: 5 VGVIMGSTSDWETMQHACEILEELEVPYEKKVVSAHRTPDLMFQYAETAQERGLKVIIAG 64 Query: 65 AGGAAHLPGMVAAKTMLPVIGVPVQSKALNGLDSLLSIVQMPGGIPVATVAIGRAGATNA 124 AGGAAHLPGMVAAKT++PVIGVPVQSKALNGLDSLLSIVQMPGG+PVATVAIG+AGATNA Sbjct: 65 AGGAAHLPGMVAAKTVVPVIGVPVQSKALNGLDSLLSIVQMPGGVPVATVAIGKAGATNA 124 Query: 125 GLLAAQIIGAFDPEVQSRAQQRRDAIQREVLESSESL 161 GLLAAQ+IGAFD +V R + RR+ +++ VLESSESL Sbjct: 125 GLLAAQMIGAFDHQVAERVRLRREKVEQAVLESSESL 161 >Q65MT4.1 Q65MT4_BACLD PurE Length = 162 Score = 253 bits (647), Expect = 3e-66, Method: Compositional matrix adjust. Identities = 123/161 (76%), Positives = 142/161 (88%) Query: 1 MSVQVGVIMGSKSDWETMEHACIVLEELGVAYEKKVISAHRTPDLMFRYAEEAAGRGLRV 60 M +GVIMGS SDWETM+HAC +L+ELG+ +EKKV+SAHRTPDLMF YAE+A RGL+V Sbjct: 1 MQPLLGVIMGSTSDWETMKHACGILDELGIPFEKKVVSAHRTPDLMFEYAEKARERGLKV 60 Query: 61 IIAGAGGAAHLPGMVAAKTMLPVIGVPVQSKALNGLDSLLSIVQMPGGIPVATVAIGRAG 120 IIAGAGGAAHLPGMVAAKT LPVIGVPVQSKALNGLDSLLSIVQMPGG+PVATVAIG+AG Sbjct: 61 IIAGAGGAAHLPGMVAAKTTLPVIGVPVQSKALNGLDSLLSIVQMPGGVPVATVAIGKAG 120 Query: 121 ATNAGLLAAQIIGAFDPEVQSRAQQRRDAIQREVLESSESL 161 A NAGLLAAQI+ AFD E+ R +RR++I++ VLESS+ L Sbjct: 121 AVNAGLLAAQILSAFDKELAERLDERRESIRQTVLESSDQL 161 >B4AI89.1 B4AI89_BACPU Phosphoribosylaminoimidazole carboxylase, catalytic subunit EC=4.1.1.21 Length = 162 Score = 253 bits (645), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 122/161 (75%), Positives = 142/161 (88%) Query: 1 MSVQVGVIMGSKSDWETMEHACIVLEELGVAYEKKVISAHRTPDLMFRYAEEAAGRGLRV 60 M VGVIMGS SDWETM++AC +LEEL ++YEK+V+SAHRTPDLMF YA EA G+GL+V Sbjct: 1 MKPLVGVIMGSTSDWETMKNACDILEELDISYEKQVVSAHRTPDLMFEYATEARGKGLKV 60 Query: 61 IIAGAGGAAHLPGMVAAKTMLPVIGVPVQSKALNGLDSLLSIVQMPGGIPVATVAIGRAG 120 IIAGAGGAAHLPGMVAAKT LPVIGVPVQSKALNGLDSLLSIVQMPGG+PVATVAIG+AG Sbjct: 61 IIAGAGGAAHLPGMVAAKTTLPVIGVPVQSKALNGLDSLLSIVQMPGGVPVATVAIGKAG 120 Query: 121 ATNAGLLAAQIIGAFDPEVQSRAQQRRDAIQREVLESSESL 161 ATNAGLLAAQ+I AFD + +R ++RR+ ++ VLESS+ L Sbjct: 121 ATNAGLLAAQMISAFDETIAARLEERREQTKQTVLESSDQL 161 >A8FAM1.1 A8FAM1_BACP2 Phosphoribosylaminoimidazole carboxylase catalytic subunit EC=4.1.1.21 Length = 162 Score = 252 bits (643), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 122/161 (75%), Positives = 141/161 (87%) Query: 1 MSVQVGVIMGSKSDWETMEHACIVLEELGVAYEKKVISAHRTPDLMFRYAEEAAGRGLRV 60 M VGVIMGS SDWETM++AC +LEEL + YEK+V+SAHRTPDLMF YA EA G+GL+V Sbjct: 1 MKPLVGVIMGSTSDWETMKNACDILEELDIPYEKQVVSAHRTPDLMFEYATEARGKGLKV 60 Query: 61 IIAGAGGAAHLPGMVAAKTMLPVIGVPVQSKALNGLDSLLSIVQMPGGIPVATVAIGRAG 120 IIAGAGGAAHLPGMVAAKT LPVIGVPVQSKALNGLDSLLSIVQMPGG+PVATVAIG+AG Sbjct: 61 IIAGAGGAAHLPGMVAAKTTLPVIGVPVQSKALNGLDSLLSIVQMPGGVPVATVAIGKAG 120 Query: 121 ATNAGLLAAQIIGAFDPEVQSRAQQRRDAIQREVLESSESL 161 ATNAGLLAAQ+I AFD + +R ++RR+ ++ VLESS+ L Sbjct: 121 ATNAGLLAAQMISAFDETIAARLEKRREQTKQTVLESSDQL 161 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.133 0.369 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 887,153,682 Number of extensions: 34778284 Number of successful extensions: 121738 Number of sequences better than 1.0e-05: 1564 Number of HSP's gapped: 121141 Number of HSP's successfully gapped: 1569 Length of query: 161 Length of database: 3,060,696,203 Length adjustment: 121 Effective length of query: 40 Effective length of database: 1,920,753,388 Effective search space: 76830135520 Effective search space used: 76830135520 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 126 (53.1 bits)