BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0207.0009.p (325 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q086Z4.1 Q086Z4_SHEFN Aldo/keto reductase 346 2e-93 Q15W39.1 Q15W39_PSEA6 Aldo/keto reductase 343 2e-92 Q3ILE4.1 Q3ILE4_PSEHT Putative oxidoreductase, Aldo/keto reducta... 340 7e-92 A5KXB0.1 A5KXB0_9GAMM Aldo/keto reductase 335 5e-90 A3US12.1 A3US12_VIBSP Oxidoreductase, aldo/keto reductase family 325 4e-87 >Q086Z4.1 Q086Z4_SHEFN Aldo/keto reductase Length = 323 Score = 346 bits (888), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 166/321 (51%), Positives = 212/321 (66%), Gaps = 1/321 (0%) Query: 5 LPLNKRSIPASRIALGCMGLGGGWDHEPVTAENVKQGHEAVEAALAIGINFFDHADIYTR 64 LPL + S I GCMGLGGGW++ + +++Q HE ++ AL IN+FDHADIYT Sbjct: 4 LPLTEFLPNVSPIVYGCMGLGGGWNNNAIIKADIQQAHEVIDTALDNQINYFDHADIYTF 63 Query: 65 GKAEKVFGQIFKERPGLRDEIILQSKCGIKLMEPGDRSNVFDFSKEHILNSVDGTLTRLG 124 GKAE VFG++ +RP LR+++ LQ+KCGI+ E +D S E I SVD +L +L Sbjct: 64 GKAESVFGKVLAQRPELREKMYLQTKCGIRF-EDSKGPKRYDLSAEWIKYSVDNSLKQLN 122 Query: 125 TEYIDILLLHRPDPLMDPEEVAEALHQLKAAGKVRHFGVSNMSAAQIKLLQAYCDEPFIV 184 EY+D+L+LHRPDPLM P E+AE QLKAAGKVR GVSNM QI LQ EP +V Sbjct: 123 AEYLDVLVLHRPDPLMQPAEIAETFQQLKAAGKVRFLGVSNMQQHQISALQRMLGEPLVV 182 Query: 185 NQLHMSLAKISWVDAVISVNREPWKDITFPEGTIEHCRAENIQLQAWGPLAQGIFSGRPL 244 NQ+ MSL K +WVD + + KDI F GT+E+C NIQ+QAWG L QGI+SG Sbjct: 183 NQIEMSLQKHAWVDETVYAGNQDGKDINFTPGTLEYCNQHNIQIQAWGSLCQGIYSGIAT 242 Query: 245 EGQPENIVNTASMVKTLAEEKNTTPEAIVLSWLMTHPAAIQPVIGTVNPGRIAACRDAGK 304 Q + T+ +V TLA E +T+PEA++LSWLM HP+ IQPVIGT N RI AC A Sbjct: 243 TEQSTAVQQTSQLVATLAAEYHTSPEAVLLSWLMQHPSQIQPVIGTTNLERIKACAKATN 302 Query: 305 LELSRREWYDLYVSSRGEKLP 325 + LSR WY LYVS++G +LP Sbjct: 303 VSLSREHWYALYVSAKGHELP 323 >Q15W39.1 Q15W39_PSEA6 Aldo/keto reductase Length = 325 Score = 343 bits (879), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 164/321 (51%), Positives = 212/321 (66%), Gaps = 1/321 (0%) Query: 5 LPLNKRSIPASRIALGCMGLGGGWDHEPVTAENVKQGHEAVEAALAIGINFFDHADIYTR 64 PL S IA GCMGLGG WD P+T +V+Q ++ V AL GINFFDHADIYT Sbjct: 6 FPLAHYLPNVSSIAYGCMGLGGNWDDSPITDAHVEQANDCVNTALESGINFFDHADIYTL 65 Query: 65 GKAEKVFGQIFKERPGLRDEIILQSKCGIKLMEPGDRSNVFDFSKEHILNSVDGTLTRLG 124 GKAE+VFG++ ERP LR +I +QSKCGI+ + + +D S + I SV+ +L RL Sbjct: 66 GKAEQVFGKVLSERPQLRKQIYIQSKCGIRFAD-ANGPKRYDLSADWIEASVESSLQRLN 124 Query: 125 TEYIDILLLHRPDPLMDPEEVAEALHQLKAAGKVRHFGVSNMSAAQIKLLQAYCDEPFIV 184 T+Y+D+L+LHRPDPLM PEE+A LK GKV HF VSNM QI LQ DEP + Sbjct: 125 TDYLDVLMLHRPDPLMQPEEIARVFEALKREGKVHHFAVSNMQHHQIAFLQRALDEPLVA 184 Query: 185 NQLHMSLAKISWVDAVISVNREPWKDITFPEGTIEHCRAENIQLQAWGPLAQGIFSGRPL 244 NQ+ SL K W+D + +DI F GT+E+CR +NIQLQ+WG LAQG++SGR + Sbjct: 185 NQIEASLLKQDWIDEGVYAGNSEGRDINFTSGTLEYCRRQNIQLQSWGSLAQGVYSGRDV 244 Query: 245 EGQPENIVNTASMVKTLAEEKNTTPEAIVLSWLMTHPAAIQPVIGTVNPGRIAACRDAGK 304 + Q + + T+ +V TLA NT+ EAIVL+WLM HPA +QPVIGT + RIAA A Sbjct: 245 KEQSDAVQRTSQLVATLAGIYNTSSEAIVLAWLMRHPAQLQPVIGTTDCARIAASCQAMN 304 Query: 305 LELSRREWYDLYVSSRGEKLP 325 ++LSR WY LY S++G +LP Sbjct: 305 IQLSREHWYALYESAKGHELP 325 >Q3ILE4.1 Q3ILE4_PSEHT Putative oxidoreductase, Aldo/keto reductase family EC=1.1.1.- Length = 323 Score = 340 bits (873), Expect = 7e-92, Method: Compositional matrix adjust. Identities = 164/321 (51%), Positives = 219/321 (68%), Gaps = 3/321 (0%) Query: 6 PLNKRSIPASRIALGCMGLGGGWDHEPVTAENVKQGHEAVEAALAIGINFFDHADIYTRG 65 PL K S++ GCMGLGGGW+ +P+T + +Q H ++ A+A GIN FDHADIYT G Sbjct: 5 PLAKYLPNVSKLIFGCMGLGGGWNKDPLTNTHTQQAHVCIDTAIAGGINLFDHADIYTFG 64 Query: 66 KAEKVFGQIFKERPGLRDEIILQSKCGIKLM-EPGDRSNVFDFSKEHILNSVDGTLTRLG 124 KAE+VFGQ+ K+RP LR++I +QSKCGI+ E G + +D SK+ I SV+G+L RL Sbjct: 65 KAEQVFGQVLKQRPELREQIYIQSKCGIRFADEQGPKR--YDLSKQWIEQSVEGSLKRLN 122 Query: 125 TEYIDILLLHRPDPLMDPEEVAEALHQLKAAGKVRHFGVSNMSAAQIKLLQAYCDEPFIV 184 T+Y+D+L+LHRPDPL+ EEVA+ +LK +GKVRHF VSNMS QI+ LQ D P + Sbjct: 123 TDYLDVLMLHRPDPLIQVEEVAQVFSRLKESGKVRHFAVSNMSQQQIQFLQTALDMPIVA 182 Query: 185 NQLHMSLAKISWVDAVISVNREPWKDITFPEGTIEHCRAENIQLQAWGPLAQGIFSGRPL 244 NQ+ SL + +WVD + V KDI F G IE+C + IQ+Q+WG L QG++SG+ L Sbjct: 183 NQIEASLKQSAWVDEGVYVGNRDGKDINFTPGFIEYCTEQEIQIQSWGSLCQGLYSGKQL 242 Query: 245 EGQPENIVNTASMVKTLAEEKNTTPEAIVLSWLMTHPAAIQPVIGTVNPGRIAACRDAGK 304 + +NTA +V LA T+ EAIVL+WL+ HPA IQPVIGT N R+AA A Sbjct: 243 QNASPADINTAILVAKLAALYRTSAEAIVLAWLLRHPALIQPVIGTTNAKRLAASCSAVN 302 Query: 305 LELSRREWYDLYVSSRGEKLP 325 +EL+R WY LYVS++G +LP Sbjct: 303 IELTREHWYALYVSAKGHELP 323 >A5KXB0.1 A5KXB0_9GAMM Aldo/keto reductase Length = 336 Score = 335 bits (858), Expect = 5e-90, Method: Compositional matrix adjust. Identities = 162/323 (50%), Positives = 216/323 (66%), Gaps = 1/323 (0%) Query: 3 KTLPLNKRSIPASRIALGCMGLGGGWDHEPVTAENVKQGHEAVEAALAIGINFFDHADIY 62 K +PL+ +IA GCMGLGGGW+ PVTAE+V Q ++ ALA GIN FDHADIY Sbjct: 15 KNIPLSNHLEGVGQIAYGCMGLGGGWNENPVTAEDVAQTRSVIDTALASGINLFDHADIY 74 Query: 63 TRGKAEKVFGQIFKERPGLRDEIILQSKCGIKLMEPGDRSNVFDFSKEHILNSVDGTLTR 122 T KAE+ FGQ ++ P LRD++ +QSKCGI+ + G+ +DFS + + SV+G L R Sbjct: 75 TFSKAEQAFGQALQQAPELRDQMFIQSKCGIRFEDEGNVGR-YDFSADWVGQSVEGILNR 133 Query: 123 LGTEYIDILLLHRPDPLMDPEEVAEALHQLKAAGKVRHFGVSNMSAAQIKLLQAYCDEPF 182 L TE +D+LLLHRPDPLM+ +E+A L LK GKV FGVSNM++ QI+ LQ+ +P Sbjct: 134 LNTEKLDVLLLHRPDPLMELDELARTLENLKVQGKVDFFGVSNMNSHQIQYLQSALGQPI 193 Query: 183 IVNQLHMSLAKISWVDAVISVNREPWKDITFPEGTIEHCRAENIQLQAWGPLAQGIFSGR 242 + NQ+ MSLAK+ W++ + +N + F GT+EHC+ + IQLQAWG LAQG F+ + Sbjct: 194 VANQIEMSLAKLDWLNDGVMINSQGHHQSDFAAGTLEHCQMKGIQLQAWGCLAQGRFAKQ 253 Query: 243 PLEGQPENIVNTASMVKTLAEEKNTTPEAIVLSWLMTHPAAIQPVIGTVNPGRIAACRDA 302 L + EN+ TA V LA + EAIVL++L+ HPA IQPVIGT N RI A A Sbjct: 254 GLYSEHENVKKTAHYVAQLANQYGVESEAIVLAFLLRHPAGIQPVIGTTNLERIKASSVA 313 Query: 303 GKLELSRREWYDLYVSSRGEKLP 325 ++ L+R EWY+LYV SRG+ LP Sbjct: 314 TQINLTREEWYNLYVYSRGQALP 336 >A3US12.1 A3US12_VIBSP Oxidoreductase, aldo/keto reductase family Length = 336 Score = 325 bits (833), Expect = 4e-87, Method: Compositional matrix adjust. Identities = 157/323 (48%), Positives = 215/323 (66%), Gaps = 1/323 (0%) Query: 3 KTLPLNKRSIPASRIALGCMGLGGGWDHEPVTAENVKQGHEAVEAALAIGINFFDHADIY 62 K++PL+ ++A GCMGLGGGW+ PVT+ +V Q ++ +L GIN FDHADIY Sbjct: 15 KSIPLSNYLPNVGQVAYGCMGLGGGWNDNPVTSADVAQTRSVIDTSLESGINLFDHADIY 74 Query: 63 TRGKAEKVFGQIFKERPGLRDEIILQSKCGIKLMEPGDRSNVFDFSKEHILNSVDGTLTR 122 T KAE+ FGQ ++ P LR+++ +QSKCGI+ G+ +DFS + + SVD L R Sbjct: 75 TFSKAEQAFGQALQQAPELREQMFIQSKCGIRFEGEGNVGR-YDFSADWVSQSVDSILNR 133 Query: 123 LGTEYIDILLLHRPDPLMDPEEVAEALHQLKAAGKVRHFGVSNMSAAQIKLLQAYCDEPF 182 L TE +D+LLLHRPDPLM+ +E+A AL LKA GKV FGVSNM++ QI+ LQ+ +P Sbjct: 134 LNTEKLDVLLLHRPDPLMELDELARALEHLKAQGKVDFFGVSNMNSHQIQYLQSALGQPI 193 Query: 183 IVNQLHMSLAKISWVDAVISVNREPWKDITFPEGTIEHCRAENIQLQAWGPLAQGIFSGR 242 + NQ+ MSLAK+ W++ + +N + F GT+EHC+ +IQLQAWG LAQG F+ + Sbjct: 194 VANQVEMSLAKLDWLNDGVMINSQGHHQSDFAAGTLEHCQMNDIQLQAWGCLAQGRFAEQ 253 Query: 243 PLEGQPENIVNTASMVKTLAEEKNTTPEAIVLSWLMTHPAAIQPVIGTVNPGRIAACRDA 302 L + E++ TA V LA + EAIVL++L+ HPA IQPVIGT N R+ A A Sbjct: 254 GLYSEHEHVKKTAHYVTQLANQYGVESEAIVLAFLLRHPARIQPVIGTTNLDRVKASAVA 313 Query: 303 GKLELSRREWYDLYVSSRGEKLP 325 ++ LSR EWY+LYV SRG+ LP Sbjct: 314 TQINLSREEWYNLYVYSRGQALP 336 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,937,895,410 Number of extensions: 77800374 Number of successful extensions: 238207 Number of sequences better than 1.0e-05: 6378 Number of HSP's gapped: 229051 Number of HSP's successfully gapped: 6387 Length of query: 325 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 189 Effective length of database: 1,779,438,163 Effective search space: 336313812807 Effective search space used: 336313812807 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 131 (55.1 bits)