BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0207.0005.p (597 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K4E5.1 B3K4E5_9BACI Diguanylate cyclase 734 0.0 Q5KYW0.1 Q5KYW0_GEOKA Hypothetical conserved protein 498 e-139 A4IP46.1 A4IP46_GEOTN Putative uncharacterized protein 481 e-133 B4BMH5.1 B4BMH5_9BACI Diguanylate cyclase and metal dependent ph... 481 e-133 B7GI63.1 B7GI63_ANOFW Multidomain signal transduction protein, d... 472 e-131 >B3K4E5.1 B3K4E5_9BACI Diguanylate cyclase Length = 618 Score = 734 bits (1896), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/596 (57%), Positives = 438/596 (73%) Query: 1 LYSFIICLIGLGLFVIYSEGSFLHFSFSAWGWITAMAGAAVILTVFTFQLPPQGNGLSLD 60 LY + L+G F++ +G H++ S W W+ AM GAA+IL FTFQLPP+GN S+D Sbjct: 17 LYFVFLSLLGCSTFLLVHQGEIFHYTPSQWVWVYAMLGAALILNYFTFQLPPEGNLQSMD 76 Query: 61 SSVYLACIFIFGLSFTXXXXXXXXXXXXXXEWGSTAGKHINNFSIYCIMIASASFIFTAL 120 SSVYLACIFI+G F + KH NFS+Y +MI +SFIF Sbjct: 77 SSVYLACIFIYGAPFALSVILFVSLAMALYDRKIPFWKHFVNFSVYTVMIVGSSFIFKMA 136 Query: 121 GGMQGPLLSSHLEAYVSAMAVYFILNTLLIGFYYYVVFHKNLYNTLKGMLTDTILAYACX 180 GG GP+ + AYV+A+ VYF++N L+GFYYY+++ +LY+ LK + DT+L Y Sbjct: 137 GGQAGPIHNDQFGAYVAALVVYFVINVFLVGFYYYLLYKGSLYDILKTFMKDTLLVYLST 196 Query: 181 XXXXXXXXXXXYHNHMVGLGLFLCLSILISYSFKRLFSMYRDIEERFNRDPRTGLFTHSY 240 HN + GL LF+ LS+++SYSFK+LF+MY+ ++E+ +D RTGL+ HSY Sbjct: 197 LILSLVLSILIVHNGVFGLTLFIGLSVMLSYSFKQLFTMYKQVQEKAIKDQRTGLYNHSY 256 Query: 241 FEQALEEEMSSSKISGTALSLAMIDIDDFKKYNDHFGHLKGDGLIVFLAELLKRETENTN 300 FE LE+E+ +K + T LSLAMIDIDDFKKYND FGHLKGD L+ FL LK E+E Sbjct: 257 FENLLEDEIKKAKTNETPLSLAMIDIDDFKKYNDQFGHLKGDMLLGFLGNYLKVESETAE 316 Query: 301 IIVSRYGGEEFTLLMPGYDAAAARNFMESLRRTLNHSRFEGSEIFPQGCLAFSAGIAAYQ 360 ++ SR+GGEEFT+LMPGYD AR+F+ LR+ LN + F+G EIFP GCL+FSAG+A+Y+ Sbjct: 317 VVASRFGGEEFTILMPGYDDHKARSFINRLRKKLNDTYFDGVEIFPSGCLSFSAGVASYR 376 Query: 361 PDVHFKSELVDHADQALYYAKKQGKNLVHTYGSQSLLEQDIDFSQDVRDIEQQLNLFMYK 420 D+H KS+LV+ ADQALYYAKKQGKN VH YGS + E +IDF++DVRDIEQQL LF+YK Sbjct: 377 IDIHDKSQLVELADQALYYAKKQGKNNVHVYGSGAEKESEIDFAEDVRDIEQQLKLFLYK 436 Query: 421 DLETFKHSKRVFRYAMDISELLNLDTLSKRQFTLGALIHDIGKLEIPWGILNKKDKLSLE 480 D++TFKHSKRVFRYAMDISE+L LD++ +R F LGALIHDIGKLEIPWGILNK+DKL+ Sbjct: 437 DVDTFKHSKRVFRYAMDISEVLGLDSVERRNFVLGALIHDIGKLEIPWGILNKRDKLTAG 496 Query: 481 EWEMVKWHVTWGKEMALTNEKFKDLAPYIELHHERYDGKGYPYGFKGDEIPRLCRMLTII 540 EWE VK HV+WGK +A TNEKFK+L PYIELHHERYDG GYP+GF+G +IP+LCRMLTII Sbjct: 497 EWETVKRHVSWGKRIAETNEKFKELVPYIELHHERYDGGGYPHGFRGSQIPKLCRMLTII 556 Query: 541 DSFDAMTTERPYQPTKSFKEAVVELRACAGSQFDPELTELFIRYIEKREVCGSEAA 596 DSFDAMTTERPYQ TK+F+E + EL C+G+QFDPEL ELFIRY+ + + A Sbjct: 557 DSFDAMTTERPYQKTKTFEEGIEELLRCSGTQFDPELVELFIRYLRLKAEAQQQPA 612 >Q5KYW0.1 Q5KYW0_GEOKA Hypothetical conserved protein Length = 608 Score = 498 bits (1282), Expect = e-139, Method: Compositional matrix adjust. Identities = 255/590 (43%), Positives = 364/590 (61%), Gaps = 7/590 (1%) Query: 1 LYSFIICLIGLGLFVIYSEGSFLHFSFSAWGWITAMAGAAVILTVFTFQLPPQGNGLSLD 60 +Y F+I I L FV+ +G F S W ++ + A ++L+ F+ LPP+ N S+D Sbjct: 11 VYLFLIFFISLITFVV-GDG-FSIPSLKDWVFVYFLVAAVLLLSYFSVHLPPKDNSFSMD 68 Query: 61 SSVYLACIFIFGLSFTXXXXXXXXXXXXXXEWGSTAGKHINNFSIYCIMIASASFIFTAL 120 S++YLA +F++G+S + KH+ N S+Y +MIA A + F Sbjct: 69 SAIYLAVMFLYGISLALKVLLISILVEFLYKRKMAWWKHLFNLSMYSLMIAGAFYSFLYF 128 Query: 121 GGMQGPLLSSHLEAYVSAMAVYFILNTLLIGFYYYVVFHKNLYNTLK--GMLTDTILAYA 178 GG G + + +L Y+ ++ VYF++N LI + + VF + +Y G+L + +++Y Sbjct: 129 GGQIGEIKTDYLFPYMVSLLVYFLINISLI--FMFFVFLERVYKGAFNFGVLFEAMVSYC 186 Query: 179 CXXXXXXXXXXXXYHNHMVGLGLFLCLSILISYSFKRLFSMYRDIEERFNRDPRTGLFTH 238 GL LF L I++S F++ +Y + R N+D TGL+ H Sbjct: 187 VTLILSLVLAILLDKERYFGLFLFTVLVIILSVVFRKFIVLYELVSNRANKDHLTGLYNH 246 Query: 239 SYFEQALEEEMSSSKISGTALSLAMIDIDDFKKYNDHFGHLKGDGLIVFLAELLKRETEN 298 +F++AL+E+ S K+ L+LA +D+DDFKKYND GHL+GD L+ F +LL++ Sbjct: 247 GFFKEALKEQFSDCKLLKQPLTLAFLDLDDFKKYNDRNGHLQGDRLLTFFGKLLQKAVGG 306 Query: 299 TNIIVSRYGGEEFTLLMPGYDAAAARNFMESLRRTLNHSRFEGSEIFPQGCLAFSAGIAA 358 TN V+RYGGEEF +LMP A F+ LR+ +N + FEG E P CL+FS GIA Sbjct: 307 TNFTVARYGGEEFAILMPNTTKEDAYAFLNRLRKEVNDTYFEGVEHIPYRCLSFSCGIAE 366 Query: 359 YQPDVHFKSELVDHADQALYYAKKQGKNLVHTYGSQSLLEQDIDFSQDVRDIEQQLNLFM 418 + D+H EL+ ADQALYYAK QGKN V Y ++ +I F QD+ +EQQ+ F+ Sbjct: 367 MEKDMHESDELIHRADQALYYAKAQGKNNVQLYDKHNMCLDEIKFKQDLEALEQQVKFFL 426 Query: 419 YKDLETFKHSKRVFRYAMDISELLNLDTLSKRQ-FTLGALIHDIGKLEIPWGILNKKDKL 477 KD+ T++HSKRVF+YA++ L+ T +RQ LGALIHDIGK+E+P ILNK+ KL Sbjct: 427 SKDVYTYRHSKRVFKYALEFGSRLDELTDHERQTLILGALIHDIGKIEVPRDILNKRGKL 486 Query: 478 SLEEWEMVKWHVTWGKEMALTNEKFKDLAPYIELHHERYDGKGYPYGFKGDEIPRLCRML 537 EWE++K HVTWG+E+ ++F DL P +ELHHERYDGKGYPYG KG+EIP+L R+L Sbjct: 487 EKHEWEIIKKHVTWGREIVAAEKRFDDLLPLVELHHERYDGKGYPYGLKGEEIPKLARIL 546 Query: 538 TIIDSFDAMTTERPYQPTKSFKEAVVELRACAGSQFDPELTELFIRYIEK 587 IIDSFDAMTTERPYQPTK+F+EA+ E+ CAG+QFDP FI ++ + Sbjct: 547 CIIDSFDAMTTERPYQPTKTFEEALEEIERCAGTQFDPVYAAKFIAFVRE 596 >A4IP46.1 A4IP46_GEOTN Putative uncharacterized protein Length = 608 Score = 481 bits (1237), Expect = e-133, Method: Compositional matrix adjust. Identities = 250/591 (42%), Positives = 373/591 (63%), Gaps = 7/591 (1%) Query: 1 LYSFIICLIGLGLFVIYSEGSFLHFSFSAWGWITAMAGAAVILTVFTFQLPPQGNGLSLD 60 +Y I LI L +F + E F++ S W ++ ++ A ++L+ F+ LPP+GN S+D Sbjct: 11 IYLSFITLIALSIF--WVEDVFVNHSLKDWVFVYILSAAVLLLSYFSIHLPPKGNSFSMD 68 Query: 61 SSVYLACIFIFGLSFTXXXXXXXXXXXXXXEWGSTAGKHINNFSIYCIMIASASFIFTAL 120 S++YLA +F++G+ + KH++NFS+Y +MIA + + F Sbjct: 69 SAIYLAVMFLYGIHMALSILFISILVEFLYKRKMEWWKHLSNFSMYSLMIAGSYYSFLFF 128 Query: 121 GGMQGPLLSSHLEAYVSAMAVYFILNTLLIGFYYYVV--FHKNLYNTLKGMLTDTILAYA 178 GG G + + +L YV+++ +YF++N LI +++ + ++ +N G+L ++++ Y Sbjct: 129 GGDIGKIRTDNLFPYVASLLIYFLVNIALIFAFFFFLGRVYRGAFNL--GVLLESVVGYL 186 Query: 179 CXXXXXXXXXXXXYHNHMVGLGLFLCLSILISYSFKRLFSMYRDIEERFNRDPRTGLFTH 238 GL LF L I++S+ F++ +Y+ + R N+D TGL+ H Sbjct: 187 VTLILSLVLAILLAEERYFGLFLFTILVIILSFVFRKFLYLYQLVSNRANKDHLTGLYNH 246 Query: 239 SYFEQALEEEMSSSKISGTALSLAMIDIDDFKKYNDHFGHLKGDGLIVFLAELLKRETEN 298 +F++ L+E+ + K L+LA++D+DDFKKYND GHL+GD L++F +LL++ E Sbjct: 247 GFFKETLKEQFADCKRLKQPLTLALLDLDDFKKYNDRNGHLQGDRLLMFFGKLLQKAVEG 306 Query: 299 TNIIVSRYGGEEFTLLMPGYDAAAARNFMESLRRTLNHSRFEGSEIFPQGCLAFSAGIAA 358 TN ++RYGGEEF +LMP A F+ LR+ +N + F+G E P CL+FS GIA Sbjct: 307 TNFTIARYGGEEFAILMPNTTKEDAYVFLNRLRKQVNDTYFDGVEHIPYRCLSFSCGIAE 366 Query: 359 YQPDVHFKSELVDHADQALYYAKKQGKNLVHTYGSQSLLEQDIDFSQDVRDIEQQLNLFM 418 + D++ EL+ ADQALYYAK QGKN V Y ++ +I F QD+ +EQQ+ F+ Sbjct: 367 MEKDMYESDELIHRADQALYYAKAQGKNNVQLYDQHNISLNEIQFKQDLEALEQQVKFFL 426 Query: 419 YKDLETFKHSKRVFRYAMDISELLNLDTLSKRQ-FTLGALIHDIGKLEIPWGILNKKDKL 477 KD+ T++HSKRVF+YA++ L+ T +RQ +LGALIHDIGK+E+P ILNK+ KL Sbjct: 427 SKDVYTYRHSKRVFKYALEFGSRLDELTNHERQTLSLGALIHDIGKIEVPRDILNKQGKL 486 Query: 478 SLEEWEMVKWHVTWGKEMALTNEKFKDLAPYIELHHERYDGKGYPYGFKGDEIPRLCRML 537 EWE++K HVTWG+E+ ++F DL P IELHHERYDGKGYPYG KG+EIP+L R+L Sbjct: 487 EKHEWEIIKKHVTWGREIIAEEKRFDDLLPLIELHHERYDGKGYPYGLKGEEIPKLARIL 546 Query: 538 TIIDSFDAMTTERPYQPTKSFKEAVVELRACAGSQFDPELTELFIRYIEKR 588 IIDSFDAMTTERPYQPTK+F EA+ E+ CAG+QFDP FI ++ +R Sbjct: 547 CIIDSFDAMTTERPYQPTKTFDEALKEIERCAGTQFDPVYAAKFIAFVRER 597 >B4BMH5.1 B4BMH5_9BACI Diguanylate cyclase and metal dependent phosphohydrolase Length = 608 Score = 481 bits (1237), Expect = e-133, Method: Compositional matrix adjust. Identities = 250/591 (42%), Positives = 373/591 (63%), Gaps = 7/591 (1%) Query: 1 LYSFIICLIGLGLFVIYSEGSFLHFSFSAWGWITAMAGAAVILTVFTFQLPPQGNGLSLD 60 +Y I LI L +F + E F++ S W ++ ++ A ++L+ F+ LPP+GN S+D Sbjct: 11 IYLSFITLIALSIF--WVEDVFVNHSLKDWVFVYILSAAVLLLSYFSIHLPPKGNSFSMD 68 Query: 61 SSVYLACIFIFGLSFTXXXXXXXXXXXXXXEWGSTAGKHINNFSIYCIMIASASFIFTAL 120 S++YLA +F++G+ + KH++NFS+Y +MIA + + F Sbjct: 69 SAIYLAVMFLYGIHMALSILFISILVEFLYKRKMEWWKHLSNFSMYSLMIAGSYYSFLFF 128 Query: 121 GGMQGPLLSSHLEAYVSAMAVYFILNTLLIGFYYYVV--FHKNLYNTLKGMLTDTILAYA 178 GG G + + +L YV+++ +YF++N LI +++ + ++ +N G+L ++++ Y Sbjct: 129 GGDIGKIRTDNLFPYVASLLIYFLVNIALIFAFFFFLGRVYRGAFNL--GVLLESVVGYL 186 Query: 179 CXXXXXXXXXXXXYHNHMVGLGLFLCLSILISYSFKRLFSMYRDIEERFNRDPRTGLFTH 238 GL LF L I++S+ F++ +Y+ + R N+D TGL+ H Sbjct: 187 VTLILSLVLAILLAEERYFGLFLFTILVIILSFVFRKFLYLYQLVSNRANKDHLTGLYNH 246 Query: 239 SYFEQALEEEMSSSKISGTALSLAMIDIDDFKKYNDHFGHLKGDGLIVFLAELLKRETEN 298 +F++ L+E+ + K L+LA++D+DDFKKYND GHL+GD L++F +LL++ E Sbjct: 247 GFFKETLKEQFADCKRLKQPLTLALLDLDDFKKYNDRNGHLQGDRLLMFFGKLLQKAVEG 306 Query: 299 TNIIVSRYGGEEFTLLMPGYDAAAARNFMESLRRTLNHSRFEGSEIFPQGCLAFSAGIAA 358 TN ++RYGGEEF +LMP A F+ LR+ +N + F+G E P CL+FS GIA Sbjct: 307 TNFTIARYGGEEFAILMPNTTKEDAYVFLNRLRKQVNDTYFDGVEHIPYRCLSFSCGIAE 366 Query: 359 YQPDVHFKSELVDHADQALYYAKKQGKNLVHTYGSQSLLEQDIDFSQDVRDIEQQLNLFM 418 + D++ EL+ ADQALYYAK QGKN V Y ++ +I F QD+ +EQQ+ F+ Sbjct: 367 MEKDMYESDELIHRADQALYYAKAQGKNNVQLYDQHNISLNEIQFKQDLEALEQQVKFFL 426 Query: 419 YKDLETFKHSKRVFRYAMDISELLNLDTLSKRQ-FTLGALIHDIGKLEIPWGILNKKDKL 477 KD+ T++HSKRVF+YA++ L+ T +RQ +LGALIHDIGK+E+P ILNK+ KL Sbjct: 427 SKDVYTYRHSKRVFKYALEFGSRLDELTNHERQTLSLGALIHDIGKIEVPRDILNKQGKL 486 Query: 478 SLEEWEMVKWHVTWGKEMALTNEKFKDLAPYIELHHERYDGKGYPYGFKGDEIPRLCRML 537 EWE++K HVTWG+E+ ++F DL P IELHHERYDGKGYPYG KG+EIP+L R+L Sbjct: 487 EKHEWEIIKKHVTWGREIIAEEKRFDDLLPLIELHHERYDGKGYPYGLKGEEIPKLARIL 546 Query: 538 TIIDSFDAMTTERPYQPTKSFKEAVVELRACAGSQFDPELTELFIRYIEKR 588 IIDSFDAMTTERPYQPTK+F EA+ E+ CAG+QFDP FI ++ +R Sbjct: 547 CIIDSFDAMTTERPYQPTKTFDEALKEIERCAGTQFDPVYAAKFIAFVRER 597 >B7GI63.1 B7GI63_ANOFW Multidomain signal transduction protein, diguanylate cyclase/phosphodiesterase (Contains GGDEF and HD-GYP domains) Length = 609 Score = 472 bits (1215), Expect = e-131, Method: Compositional matrix adjust. Identities = 250/598 (41%), Positives = 365/598 (61%), Gaps = 13/598 (2%) Query: 6 ICLIG-----LGLFVIYSEGSFLHFSFSAWGWITAMAGAAVILTVFTFQLPPQGNGLSLD 60 IC++G L +FV F H W WI ++ +A IL+ F Q+ + S+D Sbjct: 10 ICVLGVFTCALSVFVFNFSFRFPHLE--EWVWIYFLSISAFILSRFEIQIVQNKSSFSMD 67 Query: 61 SSVYLACIFIFGLSFTXXXXXXXXXXXXXXEWGSTAGKHINNFSIYCIMIASASFIFTAL 120 S+V+LA + FGL H+ NF +Y MI SF F+ L Sbjct: 68 SAVFLATVLHFGLFIASWVLLLFYLIQIMYNRTVPIWAHLLNFFMYLTMIFFTSFSFSFL 127 Query: 121 GGMQGPLLSSHLEAYVSAMAVYFILNT-LLIGFYYYVVFH-KNLYNTLKGMLTDTILAYA 178 G G + +L Y ++ VYF++N +LIGFY + ++N G+L + AY Sbjct: 128 NGKVGGEIVYNLYPYFLSLIVYFVINVVILIGFYRSIQSKFTGIFNF--GLLKEVFFAYF 185 Query: 179 CXXXXXXXXXXXXYHNHMVGLGLFLCLSILISYSFKRLFSMYRDIEERFNRDPRTGLFTH 238 + + GL LF L +L+S +F ++ Y+++ + N+D TGL+ H Sbjct: 186 VTLLLSLVLIILIDNEGLFGLFLFTVLVVLLSITFGKVLEWYQEMANQVNKDYLTGLYNH 245 Query: 239 SYFEQALEEEMSSSKISGTALSLAMIDIDDFKKYNDHFGHLKGDGLIVFLAELLKRETEN 298 YF+ L+E +K +G S+A +D+DDFKKYND+ GH++GD L+ F+ E L+ ET++ Sbjct: 246 GYFKDYLKELFRETKKTGGQFSIAFLDLDDFKKYNDYHGHVQGDRLLKFVGEFLRNETKD 305 Query: 299 TNIIVSRYGGEEFTLLMPGYDAAAARNFMESLRRTLNHSRFEGSEIFPQGCLAFSAGIAA 358 IV+RYGGEEF + +P A FM+ LR+ LN + F+G + P C++FS G+A Sbjct: 306 LGCIVARYGGEEFAIALPRLTKHEAVAFMDQLRKKLNDTPFDGVDRLPYRCISFSCGVAE 365 Query: 359 YQPDVHFKSELVDHADQALYYAKKQGKNLVHTYGSQSLLEQDIDFSQDVRDIEQQLNLFM 418 Y+ D++ +SEL+ ADQALYY+K QGKN V Y ++ + + F +D+ IE+QL L + Sbjct: 366 YESDMYEESELLHKADQALYYSKAQGKNNVQLYDAKRISRDALKFKEDLDAIEEQLKLLL 425 Query: 419 YKDLETFKHSKRVFRYAMDISELLNLDTLSKRQFTLGALIHDIGKLEIPWGILNKKDKLS 478 YKD+ T++HSKRVF+YAM+ S+ L L KR LGAL+HDIGK+E+ I+NK KL Sbjct: 426 YKDVYTYRHSKRVFKYAMEFSDRLTLTEEEKRTLVLGALVHDIGKIEVSRDIINKTSKLD 485 Query: 479 LEEWEMVKWHVTWGKEMALTNEKFKDLAPYIELHHERYDGKGYPYGFKGDEIPRLCRMLT 538 +EWE++K HV WGKE+ L++ +F+++ P +ELHHERYDG+GYPYG KG+ IP+L R+L Sbjct: 486 PDEWEIMKKHVIWGKEIVLSDGRFEEVVPLVELHHERYDGRGYPYGLKGEAIPKLARILC 545 Query: 539 IIDSFDAMTTERPYQPTKSFKEAVVELRACAGSQFDPELTELFIRYIEK--REVCGSE 594 IIDSFDAMTT+RPYQ TK+F EA+VELR C+G+QFDP+ E FI+ IE+ E G+E Sbjct: 546 IIDSFDAMTTDRPYQRTKTFSEAIVELRRCSGTQFDPQYVEPFIQMIEEYYPEKVGNE 603 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.324 0.140 0.422 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,352,022,662 Number of extensions: 138163222 Number of successful extensions: 479307 Number of sequences better than 1.0e-05: 14608 Number of HSP's gapped: 460674 Number of HSP's successfully gapped: 14679 Length of query: 597 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 455 Effective length of database: 1,722,912,073 Effective search space: 783924993215 Effective search space used: 783924993215 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 134 (56.2 bits)