BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0206.0004.p (194 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DA70.1 B1DA70_9BACL Transcriptional regulator, TetR family 180 5e-44 A7Z1P9.1 A7Z1P9_BACA2 Putative uncharacterized protein 173 7e-42 B3KHT5.1 B3KHT5_9BACI Regulatory protein TetR 160 7e-38 A6LZI3.1 A6LZI3_CLOB8 Transcriptional regulator, TetR family 153 8e-36 B4ANI7.1 B4ANI7_BACPU Transcriptional regulator, TetR family 152 2e-35 >B1DA70.1 B1DA70_9BACL Transcriptional regulator, TetR family Length = 191 Score = 180 bits (457), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 91/192 (47%), Positives = 124/192 (64%), Gaps = 1/192 (0%) Query: 3 MARSKEFDVDNVLGKAMNVFWQQGYEKTSMQDLVAGMGIHKRSMYDTFGDKHSLYIKSME 62 MARSKEFD+D VL KAM +FW QGYEKTS+QDLV MGIH+RS+YDTFGDKH+LY+ +++ Sbjct: 1 MARSKEFDIDAVLLKAMKLFWTQGYEKTSIQDLVEHMGIHRRSIYDTFGDKHALYLMALK 60 Query: 63 RFADMTASRMEGRVEGVDSAKEAIRRLFDMIIYKQEMDPAGCLLVNSAVELANHDPETTS 122 ++ S +E R + S K AIR + + I + E P GCL+VN+AVELA HDPE + Sbjct: 61 HYSHTVWSSIEQRAQSSLSTKAAIRSVMEAAIAQNEERPKGCLMVNTAVELAMHDPELET 120 Query: 123 RVNDAFLXXXXXXXXXXXXXXXXXGEIAEHHRAADLAVFLHNALVGLRVMVKINPDPSKL 182 VN ++ GE++ LA +L+NAL+GLRVMVK KL Sbjct: 121 CVNQSW-SGTEELFRKLIIKGQQAGELSASLDPELLAPYLNNALIGLRVMVKTQNHTEKL 179 Query: 183 QRIADTTLAVLD 194 +++ TT+++LD Sbjct: 180 KKVIATTMSILD 191 >A7Z1P9.1 A7Z1P9_BACA2 Putative uncharacterized protein Length = 191 Score = 173 bits (439), Expect = 7e-42, Method: Compositional matrix adjust. Identities = 84/192 (43%), Positives = 122/192 (63%), Gaps = 1/192 (0%) Query: 3 MARSKEFDVDNVLGKAMNVFWQQGYEKTSMQDLVAGMGIHKRSMYDTFGDKHSLYIKSME 62 MAR+KEFD L KAM +FW+QGYEKTSMQDLV MG+H+RS+YDTFGDKH+L+++ + Sbjct: 1 MARNKEFDEKKALRKAMILFWEQGYEKTSMQDLVDHMGVHRRSIYDTFGDKHTLFMRVLN 60 Query: 63 RFADMTASRMEGRVEGVDSAKEAIRRLFDMIIYKQEMDPAGCLLVNSAVELANHDPETTS 122 + ++ RM+ V+ + K++IR+LF+M+I + P GCL VN+AVEL+ D E Sbjct: 61 HYVEIMEGRMKNEVKTELTVKQSIRKLFEMVIDSTQQQPKGCLAVNAAVELSLIDEEVAK 120 Query: 123 RVNDAFLXXXXXXXXXXXXXXXXXGEIAEHHRAADLAVFLHNALVGLRVMVKINPDPSKL 182 + + F+ GEI +H+ L+ F+HN+LVG+RV+ K D KL Sbjct: 121 KTTEIFI-NTEALLFDLLKHGQDQGEIPKHNDIKGLSQFIHNSLVGIRVLTKTTNDKEKL 179 Query: 183 QRIADTTLAVLD 194 + I + TL+ LD Sbjct: 180 ESIINFTLSTLD 191 >B3KHT5.1 B3KHT5_9BACI Regulatory protein TetR Length = 192 Score = 160 bits (404), Expect = 7e-38, Method: Compositional matrix adjust. Identities = 82/191 (42%), Positives = 120/191 (62%), Gaps = 1/191 (0%) Query: 3 MARSKEFDVDNVLGKAMNVFWQQGYEKTSMQDLVAGMGIHKRSMYDTFGDKHSLYIKSME 62 MARSKEF+ VL KAM +FW+QGYEKTS+ DLV MGIH+RS+YDTFGDKH+L++K+M+ Sbjct: 1 MARSKEFEESVVLDKAMKLFWEQGYEKTSLTDLVEHMGIHRRSLYDTFGDKHTLFLKAMD 60 Query: 63 RFADMTASRMEGRVEGVDSAKEAIRRLFDMIIYKQEMDPAGCLLVNSAVELANHDPETTS 122 RF + + G V+ ++A EAI+ + + +I +E P+GCL+VNSAVELA D + S Sbjct: 61 RFRAKINTELSGVVKRSETAAEAIQLIINSMIDGEEDSPSGCLMVNSAVELAMRDADVDS 120 Query: 123 RVNDAFLXXXXXXXXXXXXXXXXXGEIAEHHRAADLAVFLHNALVGLRVMVKINPDPSKL 182 + ++F GE + A +LA LH VGLRVM + + KL Sbjct: 121 KSTESF-TLSEQLFKDIILWGQRNGEFTSDYDAGELAEHLHAVCVGLRVMTRTSISKEKL 179 Query: 183 QRIADTTLAVL 193 ++ A+ ++ ++ Sbjct: 180 RQTANISIKLI 190 >A6LZI3.1 A6LZI3_CLOB8 Transcriptional regulator, TetR family Length = 192 Score = 153 bits (386), Expect = 8e-36, Method: Compositional matrix adjust. Identities = 77/192 (40%), Positives = 121/192 (63%), Gaps = 1/192 (0%) Query: 3 MARSKEFDVDNVLGKAMNVFWQQGYEKTSMQDLVAGMGIHKRSMYDTFGDKHSLYIKSME 62 M RS+EFD + VL KAM +FW+QGYEKTS+ DLV MGIH+RS+YDTFGDKH+L++K+++ Sbjct: 1 MGRSREFDENVVLQKAMELFWKQGYEKTSLNDLVEHMGIHRRSLYDTFGDKHTLFLKTVD 60 Query: 63 RFADMTASRMEGRVEGVDSAKEAIRRLFDMIIYKQEMDPAGCLLVNSAVELANHDPETTS 122 +A++ ++M+ + ++AK+AI+ +F+ I E GCL+VNSA E+A D E Sbjct: 61 FYAELIKNKMQAGISNAETAKQAIQFIFNFTIEGYEDKQWGCLIVNSATEMALRDKEIEE 120 Query: 123 RVNDAFLXXXXXXXXXXXXXXXXXGEIAEHHRAADLAVFLHNALVGLRVMVKINPDPSKL 182 ++ F+ GE + + + L+ L N L+G+RV ++I+ KL Sbjct: 121 KIEKIFM-QTEQLLADLVRKGMETGEFSCKYDSEVLSEILQNTLLGIRVQLRISASKEKL 179 Query: 183 QRIADTTLAVLD 194 RIAD ++ +L+ Sbjct: 180 HRIADFSMDLLN 191 >B4ANI7.1 B4ANI7_BACPU Transcriptional regulator, TetR family Length = 191 Score = 152 bits (383), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 80/192 (41%), Positives = 115/192 (59%), Gaps = 1/192 (0%) Query: 3 MARSKEFDVDNVLGKAMNVFWQQGYEKTSMQDLVAGMGIHKRSMYDTFGDKHSLYIKSME 62 MARSKEFD VL KAM +FW+QGYEKTSMQDLV MGIH+RS+YDTFGDK SL++ S+ Sbjct: 1 MARSKEFDEKEVLRKAMELFWEQGYEKTSMQDLVDHMGIHRRSIYDTFGDKRSLFLASLH 60 Query: 63 RFADMTASRMEGRVEGVDSAKEAIRRLFDMIIYKQEMDPAGCLLVNSAVELANHDPETTS 122 + ++ + ME + S K+ IR +F ++ + P GCL VN+A+EL+ D E Sbjct: 61 HYEELIVNEMESIISSTSSIKQTIRDVFIFVLNSIKQYPKGCLSVNAAIELSLLDKE-IG 119 Query: 123 RVNDAFLXXXXXXXXXXXXXXXXXGEIAEHHRAADLAVFLHNALVGLRVMVKINPDPSKL 182 R+ GE+++ + +++ FLHN LVG+RV++K + +L Sbjct: 120 RIVTKMFNRTEDMFNSLIKQGQTNGELSKEIDSDNISRFLHNNLVGIRVLIKTDYSKKEL 179 Query: 183 QRIADTTLAVLD 194 + I L+VLD Sbjct: 180 EGIISLALSVLD 191 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.134 0.380 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 955,914,207 Number of extensions: 34120085 Number of successful extensions: 86105 Number of sequences better than 1.0e-05: 741 Number of HSP's gapped: 85757 Number of HSP's successfully gapped: 741 Length of query: 194 Length of database: 3,060,696,203 Length adjustment: 128 Effective length of query: 66 Effective length of database: 1,854,806,283 Effective search space: 122417214678 Effective search space used: 122417214678 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 127 (53.5 bits)