BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0204.0001.p (481 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A4WA99.1 A4WA99_ENT38 Lactaldehyde dehydrogenase EC=1.2.1.22 681 0.0 B6FBZ3.1 B6FBZ3_9ENTR Putative uncharacterized protein 676 0.0 Q3S2H8.1 Q3S2H8_KLEPN Aldehyde dehydrogenase EC=1.2.1.22 674 0.0 B5XRG1.1 B5XRG1_KLEP3 Aldehyde dehydrogenase A EC=1.2.1.21 EC=1.... 674 0.0 C4X7S5.1 C4X7S5_KLEPN NAD-linked aldehyde dehydrogenase A 672 0.0 >A4WA99.1 A4WA99_ENT38 Lactaldehyde dehydrogenase EC=1.2.1.22 Length = 479 Score = 681 bits (1756), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/473 (68%), Positives = 383/473 (80%) Query: 3 KHLMYIDGQFTESEGKEWMDVTNPATDEVISQVPKATRNDVVRAIHAANKAQTAWEETPA 62 +H MYIDGQF +G+ W+DV NPAT+EVIS++P +D +AI AA++AQ AWE PA Sbjct: 6 QHPMYIDGQFVAWQGEAWIDVINPATEEVISRIPDGRADDARKAIDAADRAQPAWEALPA 65 Query: 63 VERGKYLHAIAGGIRAEADSLARLISEEVGKTLELSTVEVNFTADYMDYMAEWARRYEGE 122 +ER +L I+ GIR A ++ LI E GK +L+ VEVNFTADY+DYMAEWARRYEGE Sbjct: 66 IERANWLRKISTGIRERASEISALIVAEGGKIQQLAEVEVNFTADYIDYMAEWARRYEGE 125 Query: 123 IVQSDRDNENIFVFKRAIGVTTGILPWNFPFFLIARKMAPALITGNTIVVKPSAESPNNA 182 I+QSDR ENI VFKRA+GVTTGILPWNFPFFLIARK+APAL+TGNTIV+KPS +PNNA Sbjct: 126 ILQSDRPGENILVFKRALGVTTGILPWNFPFFLIARKLAPALLTGNTIVIKPSEFTPNNA 185 Query: 183 VAFAQIVAKAGLPQGVFNLVTGKGGEVGNELASNPKVGMVSLTGSVPAGQKVMEAAAENI 242 +AFA+IV GLP+GVFNLV G+G VG ELA NPKV MVS+TGSV AG+K+M AAA+NI Sbjct: 186 IAFAKIVDDIGLPKGVFNLVLGRGETVGQELAGNPKVAMVSMTGSVTAGEKIMAAAAKNI 245 Query: 243 IKVSLELGGKAPAIVMXXXXXXXXIKAIVDSRVINTGQVCNCAERVYVHEKIKDEFTSRL 302 KV LELGGKAPAIVM +KAIVDSRVINTGQVCNCAERVYV + I D F +RL Sbjct: 246 TKVCLELGGKAPAIVMDDADLDLAVKAIVDSRVINTGQVCNCAERVYVQKGIYDRFVNRL 305 Query: 303 VEAMKAVKYGDPLKDTDIQMGPLINKAAQESVQQKVDRAVQEGAKIALGGKKVEGAGSFF 362 EAMKAV++G+P + TDI MGPLIN AA E V+QKV RAVQEGAK+ LGG+ VEG G ++ Sbjct: 306 GEAMKAVQFGNPAERTDIAMGPLINAAALERVEQKVARAVQEGAKVVLGGQAVEGKGYYY 365 Query: 363 EPTVITGATNEMEIVQEEIFGPVIPVISFSNLDEAIALANDSEFGLTSSLYTRNLNVAMK 422 PT++ EM I+ EE FGPV+PV++F L+EA+ +ANDSE+GLTSS+YT+NLNVAMK Sbjct: 366 PPTLLLDVRQEMTIMHEETFGPVLPVVAFDTLEEALTMANDSEYGLTSSIYTQNLNVAMK 425 Query: 423 VIKCLKYGETYINRENFEAMQGFHAGWRKSGIGGADGKHGLNEYLQTHVVYLQ 475 IK LK+GETYINRENFEAMQGFHAGWRKSGIGGADGKHGLNEYLQT VVYLQ Sbjct: 426 AIKGLKFGETYINRENFEAMQGFHAGWRKSGIGGADGKHGLNEYLQTQVVYLQ 478 >B6FBZ3.1 B6FBZ3_9ENTR Putative uncharacterized protein Length = 471 Score = 676 bits (1744), Expect = 0.0, Method: Compositional matrix adjust. Identities = 322/470 (68%), Positives = 379/470 (80%) Query: 6 MYIDGQFTESEGKEWMDVTNPATDEVISQVPKATRNDVVRAIHAANKAQTAWEETPAVER 65 MYIDGQF +G W+DV NPAT+EVIS++P + +D +AI AA +AQ WE PA+ER Sbjct: 1 MYIDGQFVAWQGDAWIDVINPATEEVISRIPDGSADDARKAIDAAERAQAGWEALPAIER 60 Query: 66 GKYLHAIAGGIRAEADSLARLISEEVGKTLELSTVEVNFTADYMDYMAEWARRYEGEIVQ 125 +L I+ GIR ++ LI E GK +L+ VEVNFTADY+DYMAEWARRYEGEI+Q Sbjct: 61 ANWLRKISAGIRERVGEISALIVAEGGKIQQLAEVEVNFTADYIDYMAEWARRYEGEIIQ 120 Query: 126 SDRDNENIFVFKRAIGVTTGILPWNFPFFLIARKMAPALITGNTIVVKPSAESPNNAVAF 185 SDR ENI VFKRA+GVTTGILPWNFPFFLIARK+APAL+TGNTIV+KPS +PNNA+AF Sbjct: 121 SDRPGENILVFKRALGVTTGILPWNFPFFLIARKLAPALLTGNTIVIKPSEFTPNNAIAF 180 Query: 186 AQIVAKAGLPQGVFNLVTGKGGEVGNELASNPKVGMVSLTGSVPAGQKVMEAAAENIIKV 245 A+IV GLP+GVFNLV G+G VG ELA NPKV MVS+TGSV AG+K+M AAA+NI KV Sbjct: 181 AKIVDDIGLPKGVFNLVLGRGETVGQELAGNPKVAMVSMTGSVGAGEKIMAAAAKNITKV 240 Query: 246 SLELGGKAPAIVMXXXXXXXXIKAIVDSRVINTGQVCNCAERVYVHEKIKDEFTSRLVEA 305 LELGGKAPAIVM +KAIVDSRVINTGQVCNCAERVYV + I D F +RL EA Sbjct: 241 GLELGGKAPAIVMDDADLELAVKAIVDSRVINTGQVCNCAERVYVQKGIYDRFVNRLGEA 300 Query: 306 MKAVKYGDPLKDTDIQMGPLINKAAQESVQQKVDRAVQEGAKIALGGKKVEGAGSFFEPT 365 MKAV++G+P + TDI MGPLIN AA+E V+QKV RAVQEGAK+ LGGK VEG G F+ PT Sbjct: 301 MKAVQFGNPAERTDIAMGPLINAAARERVEQKVARAVQEGAKVVLGGKAVEGKGYFYPPT 360 Query: 366 VITGATNEMEIVQEEIFGPVIPVISFSNLDEAIALANDSEFGLTSSLYTRNLNVAMKVIK 425 ++ +M I+ EE FGPV+PV++F L+ A+A+ANDS++GLTSS+YTR+LNVAMK IK Sbjct: 361 LLLDVRQDMAIMHEETFGPVLPVVAFDTLEAALAMANDSDYGLTSSIYTRDLNVAMKAIK 420 Query: 426 CLKYGETYINRENFEAMQGFHAGWRKSGIGGADGKHGLNEYLQTHVVYLQ 475 LK+GETYINRENFEAMQGFHAGWRKSGIGGADGKHGLNEYLQT VVYLQ Sbjct: 421 GLKFGETYINRENFEAMQGFHAGWRKSGIGGADGKHGLNEYLQTQVVYLQ 470 >Q3S2H8.1 Q3S2H8_KLEPN Aldehyde dehydrogenase EC=1.2.1.22 Length = 479 Score = 674 bits (1738), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/473 (67%), Positives = 378/473 (79%) Query: 3 KHLMYIDGQFTESEGKEWMDVTNPATDEVISQVPKATRNDVVRAIHAANKAQTAWEETPA 62 +H MYIDGQF G W+DV NPAT+ ++S++P + D RAI AA +AQ WE PA Sbjct: 6 QHPMYIDGQFEPGRGDAWIDVINPATEALLSRIPDGSAEDARRAILAAERAQPGWEALPA 65 Query: 63 VERGKYLHAIAGGIRAEADSLARLISEEVGKTLELSTVEVNFTADYMDYMAEWARRYEGE 122 +ER ++L IA GIR A+ +A LI E GK +L+ VEV+FTADY+DYMAEWARRYEGE Sbjct: 66 IERARWLRKIAAGIRERAEEIAALIVAEGGKIQQLAAVEVSFTADYLDYMAEWARRYEGE 125 Query: 123 IVQSDRDNENIFVFKRAIGVTTGILPWNFPFFLIARKMAPALITGNTIVVKPSAESPNNA 182 IVQSDR ENI VFKRA+GVTTGILPWNFPFFLIARK+APALITGNTIV+KPS +PNNA Sbjct: 126 IVQSDRTGENILVFKRALGVTTGILPWNFPFFLIARKLAPALITGNTIVIKPSEFTPNNA 185 Query: 183 VAFAQIVAKAGLPQGVFNLVTGKGGEVGNELASNPKVGMVSLTGSVPAGQKVMEAAAENI 242 +AFAQIV GLP+GVFNLV G+G VG ELASNPKV MVS+TGSV AG+K+M AAA+NI Sbjct: 186 IAFAQIVHDIGLPKGVFNLVLGRGETVGQELASNPKVAMVSMTGSVAAGEKIMAAAAKNI 245 Query: 243 IKVSLELGGKAPAIVMXXXXXXXXIKAIVDSRVINTGQVCNCAERVYVHEKIKDEFTSRL 302 KV LELGGKAPAIVM +KA+VDSRVIN+GQVCNC ERVYV + I D F +RL Sbjct: 246 TKVCLELGGKAPAIVMDDADLELAVKAVVDSRVINSGQVCNCVERVYVQKGIYDRFVNRL 305 Query: 303 VEAMKAVKYGDPLKDTDIQMGPLINKAAQESVQQKVDRAVQEGAKIALGGKKVEGAGSFF 362 EA+KAV++GDP DI MGPLIN AA V+QKV +AV +GA++ALGGK V G G F+ Sbjct: 306 GEALKAVQFGDPASRDDIAMGPLINAAALARVEQKVAKAVAQGARVALGGKAVTGRGYFY 365 Query: 363 EPTVITGATNEMEIVQEEIFGPVIPVISFSNLDEAIALANDSEFGLTSSLYTRNLNVAMK 422 PT++ EM+IV EE FGPV+PV++F L+EA+A+ANDS++GLTSS+YTR+LNVAMK Sbjct: 366 PPTLLLDVRQEMDIVHEETFGPVLPVVAFDTLEEALAMANDSDYGLTSSIYTRDLNVAMK 425 Query: 423 VIKCLKYGETYINRENFEAMQGFHAGWRKSGIGGADGKHGLNEYLQTHVVYLQ 475 IK LK+GETYINRENFEAMQGFHAGWRKSG+GGADG+HGLNEYLQT VVYLQ Sbjct: 426 AIKGLKFGETYINRENFEAMQGFHAGWRKSGVGGADGRHGLNEYLQTQVVYLQ 478 >B5XRG1.1 B5XRG1_KLEP3 Aldehyde dehydrogenase A EC=1.2.1.21 EC=1.2.1.22 Length = 479 Score = 674 bits (1738), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/473 (67%), Positives = 379/473 (80%) Query: 3 KHLMYIDGQFTESEGKEWMDVTNPATDEVISQVPKATRNDVVRAIHAANKAQTAWEETPA 62 +H MYIDGQF G W+DV NPAT+ ++S++P T + AI AA +AQ AWE PA Sbjct: 6 QHQMYIDGQFVSGRGDGWIDVLNPATEALLSRIPDGTAEEARLAIDAAERAQPAWEALPA 65 Query: 63 VERGKYLHAIAGGIRAEADSLARLISEEVGKTLELSTVEVNFTADYMDYMAEWARRYEGE 122 +ER +L IA GIR A+ +A LI E GK +L+ VEV FTADY+DYMAEWARRYEGE Sbjct: 66 IERAGWLRKIAAGIRQRAEEIAGLIVAEGGKIQQLAAVEVAFTADYLDYMAEWARRYEGE 125 Query: 123 IVQSDRDNENIFVFKRAIGVTTGILPWNFPFFLIARKMAPALITGNTIVVKPSAESPNNA 182 IVQSDR ENI VFKRA+GVTTGILPWNFPFFLIARK+APALITGNTIV+KPS +PNNA Sbjct: 126 IVQSDRPGENILVFKRALGVTTGILPWNFPFFLIARKLAPALITGNTIVIKPSEFTPNNA 185 Query: 183 VAFAQIVAKAGLPQGVFNLVTGKGGEVGNELASNPKVGMVSLTGSVPAGQKVMEAAAENI 242 +AFA+IV + GLP+GVFNLV G+G VG ELA NPKV MVS+TGSV AG+K+M AAA+NI Sbjct: 186 IAFAEIVHQVGLPKGVFNLVLGRGETVGQELAGNPKVAMVSMTGSVAAGEKIMAAAAKNI 245 Query: 243 IKVSLELGGKAPAIVMXXXXXXXXIKAIVDSRVINTGQVCNCAERVYVHEKIKDEFTSRL 302 KV LELGGKAPAIVM +KA+VDSRVINTGQVCNC ERVYV + I D F +RL Sbjct: 246 TKVCLELGGKAPAIVMDDADLELAVKAVVDSRVINTGQVCNCVERVYVQQGIYDRFVNRL 305 Query: 303 VEAMKAVKYGDPLKDTDIQMGPLINKAAQESVQQKVDRAVQEGAKIALGGKKVEGAGSFF 362 EAMKAV++GDP DI MGPLIN AA++ V KV++AV +GA++ALGG+ +EG G F+ Sbjct: 306 GEAMKAVQFGDPAARDDIAMGPLINAAARDQVAGKVEKAVAQGARVALGGQPLEGKGYFY 365 Query: 363 EPTVITGATNEMEIVQEEIFGPVIPVISFSNLDEAIALANDSEFGLTSSLYTRNLNVAMK 422 PT++ EM+I+ EE FGPV+PV++FS LDEA+A+ANDS++GLTSS+YTR+LNVAMK Sbjct: 366 PPTLLLDVRQEMDIIHEETFGPVLPVVAFSTLDEALAMANDSDYGLTSSIYTRDLNVAMK 425 Query: 423 VIKCLKYGETYINRENFEAMQGFHAGWRKSGIGGADGKHGLNEYLQTHVVYLQ 475 IK LK+GETYINRENFEAMQGFHAGWRKSGIGGADG+HGLNEYLQT VVYLQ Sbjct: 426 AIKGLKFGETYINRENFEAMQGFHAGWRKSGIGGADGRHGLNEYLQTQVVYLQ 478 >C4X7S5.1 C4X7S5_KLEPN NAD-linked aldehyde dehydrogenase A Length = 479 Score = 672 bits (1735), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/473 (67%), Positives = 377/473 (79%) Query: 3 KHLMYIDGQFTESEGKEWMDVTNPATDEVISQVPKATRNDVVRAIHAANKAQTAWEETPA 62 +H MYIDGQF G W+DV NPAT+ ++S++P T + AI AA +AQ WE PA Sbjct: 6 QHPMYIDGQFVSGRGDGWIDVLNPATEALLSRIPDGTAEEARLAIDAAERAQPGWEALPA 65 Query: 63 VERGKYLHAIAGGIRAEADSLARLISEEVGKTLELSTVEVNFTADYMDYMAEWARRYEGE 122 +ER +L IA GIR AD +A LI E GK +L+ VEV FTADY+DYMAEWARRYEGE Sbjct: 66 IERAGWLRKIAAGIRQRADEIAGLIVAEGGKIQQLAAVEVAFTADYLDYMAEWARRYEGE 125 Query: 123 IVQSDRDNENIFVFKRAIGVTTGILPWNFPFFLIARKMAPALITGNTIVVKPSAESPNNA 182 IVQSDR ENI VFKRA+GVTTGILPWNFPFFLIARK+APALITGNTIV+KPS +PNNA Sbjct: 126 IVQSDRPGENILVFKRALGVTTGILPWNFPFFLIARKLAPALITGNTIVIKPSEFTPNNA 185 Query: 183 VAFAQIVAKAGLPQGVFNLVTGKGGEVGNELASNPKVGMVSLTGSVPAGQKVMEAAAENI 242 +AFA+IV + GLP+GVFNLV G+G VG ELA NPKV MVS+TGSV AG+K+M AAA+NI Sbjct: 186 IAFAEIVHQVGLPKGVFNLVLGRGETVGQELAGNPKVAMVSMTGSVAAGEKIMAAAAKNI 245 Query: 243 IKVSLELGGKAPAIVMXXXXXXXXIKAIVDSRVINTGQVCNCAERVYVHEKIKDEFTSRL 302 KV LELGGKAPAIVM +KA+VDSRVINTGQVCNC ERVYV + I D F +RL Sbjct: 246 TKVCLELGGKAPAIVMDDADLELAVKAVVDSRVINTGQVCNCVERVYVQQGIYDRFVNRL 305 Query: 303 VEAMKAVKYGDPLKDTDIQMGPLINKAAQESVQQKVDRAVQEGAKIALGGKKVEGAGSFF 362 EAMKAV++GDP DI MGPLIN AA++ V KV +AV +GA++ALGG+ +EG G F+ Sbjct: 306 GEAMKAVQFGDPATRDDIAMGPLINAAARDQVAGKVAKAVAQGARVALGGQPLEGKGYFY 365 Query: 363 EPTVITGATNEMEIVQEEIFGPVIPVISFSNLDEAIALANDSEFGLTSSLYTRNLNVAMK 422 PT++ EM+I+ EE FGPV+PV++FS LDEA+A+ANDS++GLTSS+YTR+LNVAMK Sbjct: 366 PPTLLLDVRQEMDIIHEETFGPVLPVVAFSTLDEALAMANDSDYGLTSSIYTRDLNVAMK 425 Query: 423 VIKCLKYGETYINRENFEAMQGFHAGWRKSGIGGADGKHGLNEYLQTHVVYLQ 475 IK LK+GETYINRENFEAMQGFHAGWRKSGIGGADG+HGLNEYLQT VVYLQ Sbjct: 426 AIKGLKFGETYINRENFEAMQGFHAGWRKSGIGGADGRHGLNEYLQTQVVYLQ 478 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.315 0.132 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,749,791,708 Number of extensions: 111695554 Number of successful extensions: 365771 Number of sequences better than 1.0e-05: 13613 Number of HSP's gapped: 323584 Number of HSP's successfully gapped: 13722 Length of query: 481 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 341 Effective length of database: 1,741,754,103 Effective search space: 593938149123 Effective search space used: 593938149123 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 133 (55.8 bits)