BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0202.0003.p (240 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KBA3.1 B3KBA3_9BACI CBS domain containing protein 258 4e-67 B7DPQ7.1 B7DPQ7_9BACL Putative signal-transduction protein with ... 222 2e-56 C1PT44.1 C1PT44_ALIAC Predicted signal-transduction protein cont... 219 1e-55 Q8RB45.1 Q8RB45_THETN CBS domains 199 2e-49 B0KA49.1 B0KA49_THEP3 Transcriptional regulator with CBS sensor ... 198 4e-49 >B3KBA3.1 B3KBA3_9BACI CBS domain containing protein Length = 220 Score = 258 bits (658), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 128/212 (60%), Positives = 163/212 (76%) Query: 28 IELTPRQLQIVEIVKKRAPITAEQIAEHLNLSKPTIRSDLSVLVMLEYIDAKPKVGYFPG 87 IELT RQ IV+IVKK APIT +QIAE LN+S+ T+R+DLS LV+L+YIDAKPKVGYF G Sbjct: 8 IELTTRQQDIVDIVKKHAPITGDQIAEMLNVSRATLRTDLSKLVVLDYIDAKPKVGYFLG 67 Query: 88 KKTAERLSGSYLLKETKVKDIQSIPIIIRETTTIQDAVVTLFLQDVGTLIICDGDGKLTG 147 K+ + L + KV D+ +P+I+RETTTI +AVV+LFL++VG LI+ D DG L G Sbjct: 68 KRGTRDREEKFRLLKMKVGDLHGVPVIVRETTTIHEAVVSLFLENVGNLIVTDADGHLAG 127 Query: 148 VASRKDFLKVTLGNPGAVSMPVSMVMTRQPKVVTVSPGDTVLDAAQKMIFHEVDSLPVVI 207 + SRKD LKVTLGNP A SMPVS++MTR+ V TV P DTVLDAA+K+I H++DSLPVV+ Sbjct: 128 IVSRKDLLKVTLGNPTASSMPVSLIMTRRANVTTVQPEDTVLDAARKIINHQIDSLPVVV 187 Query: 208 PGTVEENGPGLDVVGRLTKTSIVKLLLDLEAK 239 P T G VVGR+TKT+I+K+LLD+ A+ Sbjct: 188 PSTTGNPGEHWKVVGRITKTNIIKMLLDMVAE 219 >B7DPQ7.1 B7DPQ7_9BACL Putative signal-transduction protein with CBS domains Length = 240 Score = 222 bits (566), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 117/215 (54%), Positives = 160/215 (74%), Gaps = 10/215 (4%) Query: 28 IELTPRQLQIVEIVKKRAPITAEQIAEHLNLSKPTIRSDLSVLVMLEYIDAKPKVGYF-- 85 IELTPRQ +I+ +V+ PIT +QIAE L +S+PTIRSDLS+LVML +DAKP+VGYF Sbjct: 33 IELTPRQKEILRLVRTHQPITGDQIAEMLGVSRPTIRSDLSLLVMLGQLDAKPRVGYFLA 92 Query: 86 -PGKKTAERLSGSYLLKETKVKDIQSIPIIIRETTTIQDAVVTLFLQDVGTLIICDGDGK 144 P + TA ++ +V ++QS+P+I+RETTT+ DAV+T+FL+DVG LI+ D +G+ Sbjct: 93 DPPEPTA-----PVPWRDLRVGEVQSLPVIVRETTTVHDAVITMFLEDVGGLIVADDEGR 147 Query: 145 LTGVASRKDFLKVTLGNPGAVSMPVSMVMTRQPKVVTVSPGDTVLDAAQKMIFHEVDSLP 204 L GV SRKDFLK TLGN A S+PV M+MTR P + TV+P D V+DAA++MI ++VDSLP Sbjct: 148 LQGVVSRKDFLKFTLGNASATSLPVGMIMTRYPHIETVTPDDRVVDAAKRMIEYKVDSLP 207 Query: 205 VVIPGTVEENGPGLDVVGRLTKTSIVKLLLDLEAK 239 VV P + EE P + VVGR+TKT++ +L+ + A Sbjct: 208 VVEPSS-EEGQPPI-VVGRITKTTLARLVAEWGAN 240 >C1PT44.1 C1PT44_ALIAC Predicted signal-transduction protein containing cAMP-binding and CBS domains Length = 242 Score = 219 bits (559), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 112/206 (54%), Positives = 154/206 (74%), Gaps = 4/206 (1%) Query: 28 IELTPRQLQIVEIVKKRAPITAEQIAEHLNLSKPTIRSDLSVLVMLEYIDAKPKVGYFPG 87 IELTPRQ +I+ +V+ PIT +QIAE L +S+PTIRSDLS+LVML +DAKP+VGYF Sbjct: 33 IELTPRQKEILRLVQAHQPITGDQIAEMLGVSRPTIRSDLSLLVMLGQLDAKPRVGYFLA 92 Query: 88 KKTAERLSGSYLLKETKVKDIQSIPIIIRETTTIQDAVVTLFLQDVGTLIICDGDGKLTG 147 + ++ +V ++QS+P+I+RETTT+ DAV+T+FL+DVG LI+ D +G+L G Sbjct: 93 DPAEPATPVPW--RDLRVGEVQSLPVIVRETTTVHDAVITMFLEDVGGLIVADEEGRLQG 150 Query: 148 VASRKDFLKVTLGNPGAVSMPVSMVMTRQPKVVTVSPGDTVLDAAQKMIFHEVDSLPVVI 207 V SRKDFLK TLGN A S+PV M+MTR P + TV+P D V+DAA++MI ++VDSLPVV Sbjct: 151 VVSRKDFLKFTLGNASATSLPVGMIMTRYPHIETVTPNDLVVDAAKRMIEYKVDSLPVVQ 210 Query: 208 PGTVEENGPGLDVVGRLTKTSIVKLL 233 P + E+G VVGR+TKT++ +L+ Sbjct: 211 PSS--EDGKPPIVVGRITKTTLARLV 234 >Q8RB45.1 Q8RB45_THETN CBS domains Length = 219 Score = 199 bits (505), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 104/209 (49%), Positives = 146/209 (69%), Gaps = 2/209 (0%) Query: 28 IELTPRQLQIVEIVKKRAPITAEQIAEHLNLSKPTIRSDLSVLVMLEYIDAKPKVGYFPG 87 I+LTPRQ I++IVKK PIT EQIAE LN+++ T+R DL++L M ++A+PKVGYF Sbjct: 10 IQLTPRQQIIIDIVKKYQPITGEQIAEKLNVTRATLRPDLAILTMSGILEARPKVGYFYT 69 Query: 88 KKTAERLSGSYLLKETKVKDIQSIPIIIRETTTIQDAVVTLFLQDVGTLIICDGDGKLTG 147 K+ L Y+ K KVKD++S+P+++ E+T + DA+VTLFL+DVGT+ + DG G LTG Sbjct: 70 GKSPLSLIQDYI-KSIKVKDVKSVPVVVEESTPVYDAIVTLFLKDVGTIFVQDG-GFLTG 127 Query: 148 VASRKDFLKVTLGNPGAVSMPVSMVMTRQPKVVTVSPGDTVLDAAQKMIFHEVDSLPVVI 207 SRKDFLK+ +GN +PV ++MTR P ++T + V +AA K+I HEVDSLPVV Sbjct: 128 AVSRKDFLKIAIGNTDIYKVPVGIIMTRMPNIITTYDDEPVYNAAVKIIEHEVDSLPVVE 187 Query: 208 PGTVEENGPGLDVVGRLTKTSIVKLLLDL 236 P ++ G V GRL+KT+I +L + L Sbjct: 188 PVVGKDGKQGYKVTGRLSKTNITRLFVKL 216 >B0KA49.1 B0KA49_THEP3 Transcriptional regulator with CBS sensor domain, DeoR family Length = 213 Score = 198 bits (503), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 105/209 (50%), Positives = 145/209 (69%), Gaps = 2/209 (0%) Query: 28 IELTPRQLQIVEIVKKRAPITAEQIAEHLNLSKPTIRSDLSVLVMLEYIDAKPKVGYFPG 87 I+LT RQ I++IVKK PIT EQIAE LN+++ T+R DL++L M ++A+PKVGYF Sbjct: 4 IQLTNRQHIIIDIVKKHQPITGEQIAEKLNVTRATLRPDLAILTMSGILEARPKVGYFYT 63 Query: 88 KKTAERLSGSYLLKETKVKDIQSIPIIIRETTTIQDAVVTLFLQDVGTLIICDGDGKLTG 147 K+ L Y+ K KVKDI+S+P+++ E+T++ DA+VTLFL+DVGT+ + DG G LTG Sbjct: 64 GKSPLSLVEDYI-KSIKVKDIKSLPVVVEESTSVYDAIVTLFLKDVGTIFVQDG-GFLTG 121 Query: 148 VASRKDFLKVTLGNPGAVSMPVSMVMTRQPKVVTVSPGDTVLDAAQKMIFHEVDSLPVVI 207 SRKDFLK+ +GN +PV ++MTR P +VT + V +AA K+I HEVDSLPVV Sbjct: 122 AVSRKDFLKIAIGNTDIYKVPVGIIMTRMPNIVTTYDDEPVYNAAVKIIEHEVDSLPVVE 181 Query: 208 PGTVEENGPGLDVVGRLTKTSIVKLLLDL 236 P + G V GR++KT+I KL + L Sbjct: 182 PVVGSDGKQGYKVTGRISKTNITKLFVKL 210 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.136 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,364,235,479 Number of extensions: 53802568 Number of successful extensions: 158657 Number of sequences better than 1.0e-05: 235 Number of HSP's gapped: 158516 Number of HSP's successfully gapped: 235 Length of query: 240 Length of database: 3,060,696,203 Length adjustment: 132 Effective length of query: 108 Effective length of database: 1,817,122,223 Effective search space: 196249200084 Effective search space used: 196249200084 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 129 (54.3 bits)