BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0197.0004.p (188 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DM28.1 B1DM28_9BACL Transcriptional regulator, TetR family 263 6e-69 A8DR56.1 A8DR56_9BACT TetR family transcriptional regulator 123 8e-27 Q749P4.1 Q749P4_GEOSL Transcriptional regulator, TetR family 108 3e-22 A1AKU6.1 A1AKU6_PELPD Transcriptional regulator, TetR family 106 8e-22 B1DCT5.1 B1DCT5_9BACL Transcriptional regulator, TetR family 105 2e-21 >B1DM28.1 B1DM28_9BACL Transcriptional regulator, TetR family Length = 187 Score = 263 bits (672), Expect = 6e-69, Method: Compositional matrix adjust. Identities = 128/187 (68%), Positives = 153/187 (81%), Gaps = 2/187 (1%) Query: 4 MSKRDDILSATLDLIDEEGLQSVTIAKIMKRANVGSGTLFNYFSNKEELVNEVYKSARQH 63 MSK+ DI++ATLDLI EEGLQSVT +K+ KRANVG+GT++NYF+NKEELVN VYK AR Sbjct: 1 MSKKQDIMAATLDLIHEEGLQSVTFSKLFKRANVGAGTIYNYFANKEELVNAVYKEARLL 60 Query: 64 MGEALLRNYNPGLSLYERFKYLQLNRLHFGLSSPKEFLFIDSYSYSPYISADLRKMEDA- 122 MGE LL Y+P SLYERFK LQLNRL+FG+ PKEFLFIDS+S+S YIS +LR MED Sbjct: 61 MGECLLHGYDPEASLYERFKCLQLNRLNFGIQYPKEFLFIDSFSFSSYISPELRNMEDVR 120 Query: 123 -SREIMLSLIEEGQTQGLFKEMDPHLSHQIIHGIMVSIVKGFIIQKYPLDDLQVQQTLEA 181 S E++LSLI EGQ QG+ KEMD HL HQ+IHGI+ SI+KG+ I KYPL+++QVQQ LEA Sbjct: 121 HSSEVVLSLIVEGQKQGIIKEMDSHLCHQLIHGIISSILKGYYIDKYPLNEVQVQQILEA 180 Query: 182 CWKAIRV 188 WKAI V Sbjct: 181 SWKAILV 187 >A8DR56.1 A8DR56_9BACT TetR family transcriptional regulator Length = 186 Score = 123 bits (308), Expect = 8e-27, Method: Compositional matrix adjust. Identities = 63/185 (34%), Positives = 102/185 (55%) Query: 3 MMSKRDDILSATLDLIDEEGLQSVTIAKIMKRANVGSGTLFNYFSNKEELVNEVYKSARQ 62 M +KR IL ATL+LI E+G ++ I +A VG+GT++ YF KE L+ ++Y ++ Sbjct: 1 MTTKRAAILEATLELISEQGFHGTAMSMIADKAEVGAGTIYRYFDGKEALITQLYLEIKR 60 Query: 63 HMGEALLRNYNPGLSLYERFKYLQLNRLHFGLSSPKEFLFIDSYSYSPYISADLRKMEDA 122 M +A L Y+ LSL ERF+ L LN LH+ + P+E F++ + SPY +A++R+ Sbjct: 61 EMSKAFLAGYSEDLSLRERFRTLWLNMLHYYIHHPQETAFMEQFDNSPYTNAEVREACAE 120 Query: 123 SREIMLSLIEEGQTQGLFKEMDPHLSHQIIHGIMVSIVKGFIIQKYPLDDLQVQQTLEAC 182 E ++ + +G+FKEM + + VS+ K LDD + + AC Sbjct: 121 YYEPLIRFFQYAFQEGVFKEMPLEMLPTFTLDVAVSLAKQHASGGLTLDDETKELAMSAC 180 Query: 183 WKAIR 187 W A++ Sbjct: 181 WDALK 185 >Q749P4.1 Q749P4_GEOSL Transcriptional regulator, TetR family Length = 203 Score = 108 bits (269), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 59/187 (31%), Positives = 101/187 (54%), Gaps = 3/187 (1%) Query: 4 MSKRDDILSATLDLIDEEGLQSVTIAKIMKRANVGSGTLFNYFSNKEELVNEVYKSARQH 63 + KRD+I+ A L+LI E G +A I +RA VG+GT++ YF NK+ L+NE+Y+ + Sbjct: 16 LEKRDEIVRAALELIAEHGFHGAPMALIAERAGVGAGTIYRYFENKDVLINEMYQELEEK 75 Query: 64 MGEALLRNYNPGLSLYERFKYLQLNRLHFGLSSPKEFLFIDSYSYSPYISADLRKMEDAS 123 + + Y + ERF +L L + + +P +F +++ + SPY A R+ Sbjct: 76 IFPVITEGYGELKAFRERFLHLGTALLRYFIQNPLDFRYLEQFHNSPYGVATRRERLLGV 135 Query: 124 RE---IMLSLIEEGQTQGLFKEMDPHLSHQIIHGIMVSIVKGFIIQKYPLDDLQVQQTLE 180 RE + L EEG Q + K++ L + G +++ + I+ LDD + +T+E Sbjct: 136 REGCDVYFHLFEEGIAQQVLKDVPLPLLFALSFGPLLAAARDHILGFIELDDALIARTIE 195 Query: 181 ACWKAIR 187 ACW A++ Sbjct: 196 ACWDAVK 202 >A1AKU6.1 A1AKU6_PELPD Transcriptional regulator, TetR family Length = 192 Score = 106 bits (265), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 59/186 (31%), Positives = 103/186 (55%), Gaps = 4/186 (2%) Query: 6 KRDDILSATLDLIDEEGLQSVTIAKIMKRANVGSGTLFNYFSNKEELVNEVYKSARQHMG 65 KRD+I+ A L+LI E G +A I +RA VG+GT++ YF NK+ L+NE+Y+ + + Sbjct: 6 KRDEIVRAALELIAEHGFHGAPMAMIAERAGVGAGTIYRYFENKDVLINELYQEIEKRIV 65 Query: 66 EALLRNYNPGLSLYERFKYLQLNRLHFGLSSPKEFLFIDSYSYSPYISADLRK--MEDAS 123 AL + Y+ ERF +L L + +SSP +F +++ + SP+ A R + D + Sbjct: 66 AALHQGYSREKPFRERFVHLGTTLLRYFISSPLDFRYVEQFHNSPFGVAFRRDKLLGDTT 125 Query: 124 R--EIMLSLIEEGQTQGLFKEMDPHLSHQIIHGIMVSIVKGFIIQKYPLDDLQVQQTLEA 181 +++ L E G Q + K+ + + G +VS+ + I+ LD+ ++ +EA Sbjct: 126 SGCDVIKELFELGVAQQILKDFPLVILFDLFFGPVVSLARDHILGFIQLDEAMIRHIIEA 185 Query: 182 CWKAIR 187 CW A++ Sbjct: 186 CWDAVK 191 >B1DCT5.1 B1DCT5_9BACL Transcriptional regulator, TetR family Length = 193 Score = 105 bits (263), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 61/181 (33%), Positives = 101/181 (55%), Gaps = 3/181 (1%) Query: 10 ILSATLDLIDEEGLQSVTIAKIMKRANVGSGTLFNYFSNKEELVNEVYKSARQHMGEALL 69 +L TL +I + LQ+ ++A I K + V +G++++YFS+KEE++NE+Y S + G+ + Sbjct: 12 VLETTLQIIIRKELQATSMALIAKESKVSTGSIYHYFSSKEEIINELYTSIVTYNGQFVQ 71 Query: 70 RNYNPGLSLYERFKYLQLNRLHFGLSSPKEFLFIDSYSYSPYISADLRK--MEDASREIM 127 N ++ ERF + + P+ F FI+ YS+SPYI ++++ M Sbjct: 72 EGLNREGTIRERFNWGWERVIETSRQYPEGFQFIEQYSFSPYIYEEVKQKAYNGGWCAPM 131 Query: 128 LSLIEEGQTQGLFKEMDPHLSHQIIHGIMVSIVKGFIIQKYPLDDLQVQQTLEACWK-AI 186 L + Q LF+EMDP L Q+ +G MV +VK ++ L D + Q +E CW+ AI Sbjct: 132 NKLYADAMEQELFREMDPKLLVQMHYGSMVYMVKSYLQGNSDLTDAGIGQAIEVCWQGAI 191 Query: 187 R 187 R Sbjct: 192 R 192 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.137 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 995,376,821 Number of extensions: 37599067 Number of successful extensions: 114754 Number of sequences better than 1.0e-05: 404 Number of HSP's gapped: 115003 Number of HSP's successfully gapped: 404 Length of query: 188 Length of database: 3,060,696,203 Length adjustment: 128 Effective length of query: 60 Effective length of database: 1,854,806,283 Effective search space: 111288376980 Effective search space used: 111288376980 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 127 (53.5 bits)