BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0190.0005.p (592 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KDZ0.1 B3KDZ0_9BACI von Willebrand factor type A 665 0.0 C0Z8R6.1 C0Z8R6_BREBN Putative uncharacterized protein 632 e-179 B9E276.1 B9E276_CLOK1 Putative uncharacterized protein 395 e-108 A5N8S8.1 A5N8S8_CLOK5 Putative uncharacterized protein 395 e-108 C0ZJ85.1 C0ZJ85_BREBN Putative uncharacterized protein 270 2e-70 >B3KDZ0.1 B3KDZ0_9BACI von Willebrand factor type A Length = 595 Score = 665 bits (1715), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/590 (57%), Positives = 422/590 (71%), Gaps = 10/590 (1%) Query: 6 LLLLVLCIXXXXXXXXXXXXXXXXXXHIDAVLLIDVSNSMNKSDKNNIAGEAMKMFIDML 65 L+ VL I +IDAVL++D SNSM SD I+GEAMKMFIDML Sbjct: 11 LMAAVLLIMTWSGGALPKAAAASQGSNIDAVLVMDASNSMKNSDPERISGEAMKMFIDML 70 Query: 66 SAQGDKVGIVAYTDKVQREKALLQIGSAADKQDLKDFIDGLDRGAYTDIAVGMEEAVKVL 125 + GDKVGIV+YTD++QREKALL+I S ADK LK+FID LDRG YTD++VG++EAVKVL Sbjct: 71 ATTGDKVGIVSYTDRIQREKALLEIQSEADKTALKEFIDQLDRGPYTDMSVGLDEAVKVL 130 Query: 126 ENGSDPGHEPMIVMLADGNNDLNEATGRTQSQSDQELDAAVETAKQKGYPVYTIGLNADG 185 + G DP H PMIV+LADGNNDL+ TGRT ++ ++L+ AV+ AK G P+YTIGLNADG Sbjct: 131 KQGMDPAHAPMIVVLADGNNDLDPNTGRTSKEASEQLNQAVKEAKGSGIPIYTIGLNADG 190 Query: 186 KLNKEILAGLSNKTSGKAFITDSADDLPQILSEIFADHLKLKVVPVQSITANGSYQEVTV 245 KLNKE LA L+ +T GK+F T SADDLPQILSEIFA H +LK+VPVQSIT NGSYQEVTV Sbjct: 191 KLNKETLAELAKQTGGKSFTTSSADDLPQILSEIFASHQQLKIVPVQSITGNGSYQEVTV 250 Query: 246 NVPNSSVLEANISIMSAKPVTAKLTDPSGKEVAIPSDDVLLSKSSTYSLIKLLSPEQGDW 305 VPN++VLEANISIMS+ PV KL DP+G E +IPS VL S S++YSL+KLL P+QGDW Sbjct: 251 RVPNANVLEANISIMSSSPVDVKLVDPTGAEQSIPSASVLRSTSNSYSLLKLLKPQQGDW 310 Query: 306 KLQVKGVPKDKIDINLVFNYDLELKLDALQSKTYKKGDTVEISSHLYSNGAKVTLNNLYQ 365 KLQVKGV KDKIDINLVFNYDLEL +D S K GDT++I+++L SNG K+ Y Sbjct: 311 KLQVKGVSKDKIDINLVFNYDLELAMDPPPSSKVKAGDTIDINAYLVSNGQKLQDQEQYG 370 Query: 366 DMKAVLLATDTDTGKVQELPMDNTGAVFKGSFEIAESHNYELKVRAEESSFYRESDVLTI 425 +M A LL D DTG E+ ++N F G ++I + H+YEL+VRAEE SFYRES + I Sbjct: 371 NMTAKLLIKDLDTGDESEVELENKEGSFVGDYKIPQKHDYELRVRAEEQSFYRESPPVKI 430 Query: 426 NAKTGAVATSTSKPAGAGGTE-PAQDKSSSKTLYYIIGGIXXXXXXXXXXXXXR---QKS 481 +AK A + G GG E A + + L+ +I GI +K+ Sbjct: 431 SAKAAASGS------GNGGKEMTAGEDAKPFPLWPVIIGIASLLIVGAAAYFILGAIKKA 484 Query: 482 NRGFVGQMVVEVLDGNTGEKTYPQYKKLAAFRGKFTLHQLLQLAPELKESEKLVFTPGKN 541 N+GFVGQ+V+E+ D NTGEKT PQYKKL +FRGKF LHQLLQLAPELKE+EK++F PGKN Sbjct: 485 NKGFVGQIVIEIRDENTGEKTSPQYKKLTSFRGKFNLHQLLQLAPELKETEKILFMPGKN 544 Query: 542 DRLMLRGSEEISVERSGRVVDTARGLELKSGDRISVALQTVDKTILLEYL 591 DR++L+ +E+SGR +D G ELK+GDR+ V+LQ DKTIL EYL Sbjct: 545 DRIILKNLSSAVIEKSGRALDATNGTELKNGDRLRVSLQQADKTILFEYL 594 >C0Z8R6.1 C0Z8R6_BREBN Putative uncharacterized protein Length = 597 Score = 632 bits (1631), Expect = e-179, Method: Compositional matrix adjust. Identities = 309/566 (54%), Positives = 418/566 (73%), Gaps = 11/566 (1%) Query: 32 HIDAVLLIDVSNSMNKSDKNNIAGEAMKMFIDMLSAQGDKVGIVAYTDKVQREKALLQIG 91 ++DAVL++DVSNSM +SDKN ++ EAMKMF+DM S Q +KVG+VAYTDK++REKALL+I Sbjct: 38 NMDAVLVVDVSNSMTQSDKNKVSNEAMKMFVDMTSIQANKVGVVAYTDKIEREKALLEIN 97 Query: 92 SAADKQDLKDFIDGLDRGAYTDIAVGMEEAVKVLENGSDPGHEPMIVMLADGNNDLNEAT 151 S DK D+K FID L +GAYTDIAVG+ EAVK+L+ G +P + P+IV+LADGNN LN+A+ Sbjct: 98 SEEDKNDIKAFIDSLQKGAYTDIAVGVTEAVKILDAGRNPNNAPIIVLLADGNNFLNKAS 157 Query: 152 GRTQSQSDQELDAAVETAKQKGYPVYTIGLNADGKLNKEILAGLSNKTSGKAFITDSADD 211 RTQ++SDQEL AV+ AK KGYPVYTIGLNADG+LN+ L ++ +T+GK F T +AD Sbjct: 158 SRTQAKSDQELQQAVKEAKDKGYPVYTIGLNADGQLNRTTLQQIAAETNGKFFETSTADK 217 Query: 212 LPQILSEIFADHLKLKVVPVQSITANGSYQEVTVNVPNSSVLEANISIMSAKPVTAKLTD 271 LPQILSEIFA+HLKLKVVPV+S ANG QE+ + +PN SV+EANISIMS K V KL D Sbjct: 218 LPQILSEIFANHLKLKVVPVKSFVANGQAQEIPIPIPNGSVMEANISIMSQKAVEVKLYD 277 Query: 272 PSGKEVAIPSDDVLLSKSSTYSLIKLLSPEQGDWKLQVKGVPKDKIDINLVFNYDLELKL 331 P+GKEV IPS+ V LSKS+ Y++IKL+ P+QGDWKLQVKGVPK+KIDINL+FNYDL+L++ Sbjct: 278 PAGKEVKIPSNQVRLSKSNAYTMIKLVKPQQGDWKLQVKGVPKEKIDINLIFNYDLQLEM 337 Query: 332 DALQSKTYKKGDTVEISSHLYSNGAKVTLNNLYQDMKAVLLATDTDTGKVQELPMDNTGA 391 + + +K+YK GD V I + L SNG KV +LY+ MKA L+ D K E+ ++NTG+ Sbjct: 338 EPVTAKSYKAGDVVPIKAALVSNGQKVASPDLYKQMKATLIVNDKTDNKTNEVILNNTGS 397 Query: 392 VFKGSFEIAESHNYELKVRAEESSFYRESDVLTINAKTGAVATSTSKPAGAGGTEPAQDK 451 F+GSF I H YE+KV+AE++SFYRE+ L ++A A + TSKP+ T+PA Sbjct: 398 GFEGSFTIPADHTYEIKVKAEDTSFYRETKPLLVDAAKTA-GSGTSKPSTT--TDPA--- 451 Query: 452 SSSKTLYYIIGGIXXXXXXXXX-----XXXXRQKSNRGFVGQMVVEVLDGNTGEKTYPQY 506 + SK ++ +K+N+GF GQ+ +E++D +TGEK+ PQY Sbjct: 452 AESKPFPWLTVVGGILVLLLLIGAGLYALSIYRKANKGFAGQIAIEIVDEDTGEKSNPQY 511 Query: 507 KKLAAFRGKFTLHQLLQLAPELKESEKLVFTPGKNDRLMLRGSEEISVERSGRVVDTARG 566 KKL AF+GK LHQL+QLAPE E+EK++F PGKND L++ +E++GRV+D ++G Sbjct: 512 KKLNAFKGKVKLHQLMQLAPEFAETEKVIFLPGKNDTLIIENRSSCRIEKAGRVLDASKG 571 Query: 567 LELKSGDRISVALQTVDKTILLEYLI 592 ELK DRI ++L V+K++ ++Y++ Sbjct: 572 KELKKNDRIKISLTNVNKSLYVDYIV 597 >B9E276.1 B9E276_CLOK1 Putative uncharacterized protein Length = 580 Score = 395 bits (1014), Expect = e-108, Method: Compositional matrix adjust. Identities = 220/560 (39%), Positives = 338/560 (60%), Gaps = 20/560 (3%) Query: 33 IDAVLLIDVSNSMNKSDKNNIAGEAMKMFIDMLSAQGDKVGIVAYTDKVQREKALLQIGS 92 +D + ++D S SM +SD I EA+KMF+DM QG+K G+VAY+D + RE L I S Sbjct: 36 MDVIFVLDSSGSMAESDPEKIREEAIKMFLDMGQIQGNKAGLVAYSDSIVREHNLDSINS 95 Query: 93 AADKQDLKDFIDGLDRGAYTDIAVGMEEAVKVLENGSDPGHEPMIVMLADGNNDLNEATG 152 + DK +K + G TD G+ EAVK++E+G G+ P+I++L+DG ND Sbjct: 96 SEDKDRIKSMASDISLGQRTDTGRGLLEAVKLMESGHKSGNNPVIILLSDGKND----PE 151 Query: 153 RTQSQSDQELDAAVETAKQKGYPVYTIGLNADGKLNKEILAGLSNKTSGKAFITDSADDL 212 R+Q +S +L A++ K KGYPVYTIGLN +G ++K L +S+ T GK +IT++A DL Sbjct: 152 RSQDESLNDLKNALQICKSKGYPVYTIGLNYNGTVDKTQLGDISSSTGGKDYITNTASDL 211 Query: 213 PQILSEIFADHLKLKVVPVQSITANGSYQEVTVNVPNSSVLEANISIMSAKPVTAKLTDP 272 P IL++I+AD+ KLKV +I A+G +QE+ VN+PNS+VLEANIS++S+ PV KL +P Sbjct: 212 PAILTDIYADNSKLKVQDGGTIKASGDFQELKVNIPNSNVLEANISMLSSTPVEVKLLNP 271 Query: 273 SGKEVAIPSDDVLLSKSSTYSLIKLLSPEQGDWKLQVKGVPKDKIDINLVFNYDLELKLD 332 SGKEV IPS++ L + S+ YS++KL+SP +G W ++VKGV + I ++ +FNYD++LK Sbjct: 272 SGKEVLIPSENTLFTSSNKYSMLKLISPVKGAWTVKVKGVSGNDIKVSYIFNYDIQLKA- 330 Query: 333 ALQSKTYKKGDTVEISSHLYSNGAKVTLNNLYQDMKAVLLATDTDTGKVQELPMDNTGAV 392 + KGD V+I ++ SN KV LY++++A L+ + +E+P+ + + Sbjct: 331 VFTPENPVKGDKVKIQAYFTSNADKVADEELYKNVEAKLIVKNLKDNSTKEVPLTSGDNL 390 Query: 393 FKGSFEIAESHNYELKVRAEESSFYRESDVLTINAKTGAVATSTSKPAGAGGTEPAQDKS 452 FKG + E YELKVR + SFYRES+ L I TG + T Q KS Sbjct: 391 FKGEYSYLEEGKYELKVRVDGDSFYRESNTLVIGDNTGGAVSKT------------QSKS 438 Query: 453 SSKT--LYYIIGGIXXXXXXXXXXXXXRQKSNRGFVGQMVVEVLDGNTGEKTYPQYKKLA 510 K +IG I ++K RGF G++ + ++D NTGE PQ++ L Sbjct: 439 FIKNPITLTVIGIILAAICTYIIIMVIKKKRIRGF-GRIELNIMDENTGEALSPQFRNLD 497 Query: 511 AFRGKFTLHQLLQLAPELKESEKLVFTPGKNDRLMLRGSEEISVERSGRVVDTARGLELK 570 ++ G FTL +L L E E+E + F +D L + ++++SG++++ + + L Sbjct: 498 SYIGSFTLFDVLGLKEEYSETEPIKFVFKNDDSLEIVNKSNCTLQKSGKILENSSRVILY 557 Query: 571 SGDRISVALQTVDKTILLEY 590 +G++I V L V K+IL+E+ Sbjct: 558 NGNKIKVLLNKVPKSILVEF 577 >A5N8S8.1 A5N8S8_CLOK5 Putative uncharacterized protein Length = 580 Score = 395 bits (1014), Expect = e-108, Method: Compositional matrix adjust. Identities = 220/560 (39%), Positives = 338/560 (60%), Gaps = 20/560 (3%) Query: 33 IDAVLLIDVSNSMNKSDKNNIAGEAMKMFIDMLSAQGDKVGIVAYTDKVQREKALLQIGS 92 +D + ++D S SM +SD I EA+KMF+DM QG+K G+VAY+D + RE L I S Sbjct: 36 MDVIFVLDSSGSMAESDPEKIREEAIKMFLDMGQIQGNKAGLVAYSDSIVREHNLDSINS 95 Query: 93 AADKQDLKDFIDGLDRGAYTDIAVGMEEAVKVLENGSDPGHEPMIVMLADGNNDLNEATG 152 + DK +K + G TD G+ EAVK++E+G G+ P+I++L+DG ND Sbjct: 96 SEDKDRIKSMASDISLGQRTDTGRGLLEAVKLMESGHKSGNNPVIILLSDGKND----PE 151 Query: 153 RTQSQSDQELDAAVETAKQKGYPVYTIGLNADGKLNKEILAGLSNKTSGKAFITDSADDL 212 R+Q +S +L A++ K KGYPVYTIGLN +G ++K L +S+ T GK +IT++A DL Sbjct: 152 RSQDESLNDLKNALQICKSKGYPVYTIGLNYNGTVDKTQLGDISSSTGGKDYITNTASDL 211 Query: 213 PQILSEIFADHLKLKVVPVQSITANGSYQEVTVNVPNSSVLEANISIMSAKPVTAKLTDP 272 P IL++I+AD+ KLKV +I A+G +QE+ VN+PNS+VLEANIS++S+ PV KL +P Sbjct: 212 PAILTDIYADNSKLKVQDGGTIKASGDFQELKVNIPNSNVLEANISMLSSTPVEVKLLNP 271 Query: 273 SGKEVAIPSDDVLLSKSSTYSLIKLLSPEQGDWKLQVKGVPKDKIDINLVFNYDLELKLD 332 SGKEV IPS++ L + S+ YS++KL+SP +G W ++VKGV + I ++ +FNYD++LK Sbjct: 272 SGKEVLIPSENTLFTSSNKYSMLKLISPVKGAWTVKVKGVSGNDIKVSYIFNYDIQLKA- 330 Query: 333 ALQSKTYKKGDTVEISSHLYSNGAKVTLNNLYQDMKAVLLATDTDTGKVQELPMDNTGAV 392 + KGD V+I ++ SN KV LY++++A L+ + +E+P+ + + Sbjct: 331 VFTPENPVKGDKVKIQAYFTSNADKVADEELYKNVEAKLIVKNLKDNSTKEVPLTSGDNL 390 Query: 393 FKGSFEIAESHNYELKVRAEESSFYRESDVLTINAKTGAVATSTSKPAGAGGTEPAQDKS 452 FKG + E YELKVR + SFYRES+ L I TG + T Q KS Sbjct: 391 FKGEYSYLEEGKYELKVRVDGDSFYRESNTLVIGDNTGGAVSKT------------QSKS 438 Query: 453 SSKT--LYYIIGGIXXXXXXXXXXXXXRQKSNRGFVGQMVVEVLDGNTGEKTYPQYKKLA 510 K +IG I ++K RGF G++ + ++D NTGE PQ++ L Sbjct: 439 FIKNPITLTVIGIILAAICTYIIIMVIKKKRIRGF-GRIELNIMDENTGEALSPQFRNLD 497 Query: 511 AFRGKFTLHQLLQLAPELKESEKLVFTPGKNDRLMLRGSEEISVERSGRVVDTARGLELK 570 ++ G FTL +L L E E+E + F +D L + ++++SG++++ + + L Sbjct: 498 SYIGSFTLFDVLGLKEEYSETEPIKFVFKNDDSLEIVNKSNCTLQKSGKILENSSRVILY 557 Query: 571 SGDRISVALQTVDKTILLEY 590 +G++I V L V K+IL+E+ Sbjct: 558 NGNKIKVLLNKVPKSILVEF 577 >C0ZJ85.1 C0ZJ85_BREBN Putative uncharacterized protein Length = 677 Score = 270 bits (691), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 138/389 (35%), Positives = 230/389 (59%), Gaps = 9/389 (2%) Query: 33 IDAVLLIDVSNSMNKSDKNNIAGEAMKMFIDMLSAQGDKVGIVAYTDKVQREKALLQIGS 92 +DAV ++D SNSMNK+D A E M MFIDM A ++G VAY D++ + ++ + Sbjct: 45 VDAVFVVDTSNSMNKTDPGKTAAEVMSMFIDMSEATRTRIGFVAYNDRIVQAQSPASMAE 104 Query: 93 AADKQDLKDFIDGLDRGAYTDIAVGMEEAVKVLENGSDPGHEPMIVMLADGNNDLNE-AT 151 A +++ LK I GL Y+D+ +G+ +++E DP +P +++L+DG DL + A Sbjct: 105 ARNREQLKRTIQGLRYSGYSDLGLGLRRGAEMIEKAKDPARKPFLILLSDGGTDLRQNAG 164 Query: 152 GRTQSQSDQELDAAVETAKQKGYPVYTIGLNADGKLNKEILAGLSNKTSGKAFITDSADD 211 GR+ + S+++++ + AK +GYP+YTIGLN DG + KE L ++ T G +F+T S DD Sbjct: 165 GRSVAASNKDVETVISKAKAQGYPIYTIGLNNDGSVQKEQLKKIAEATGGTSFVTQSTDD 224 Query: 212 LPQILSEIFADHLKLKVVPVQSITANGSYQEVTVNVPNSSVLEANISIMSAKPVTAKLTD 271 LP+I ++IFA H++ ++V V ++TA G QEVTV +PNSS+ EANI ++S P+ Sbjct: 225 LPEIFNQIFAKHIQSQLVSVAAMTATGGLQEVTVTIPNSSMQEANIILLSNNPLLE---- 280 Query: 272 PSGKEVAIPSDDVLLSKSSTYSLIKLLSPEQGDWKLQVKGVPKDKIDINLVFNYDLELKL 331 +V S +V KS YSL+K+ P++G++ ++ +G P D + INL+ NY L + Sbjct: 281 ---SQVYYQSQNVHFMKSQKYSLMKIEKPKKGNYLVKFRGKPGDLVKINLLGNYSLMAGV 337 Query: 332 DALQSKTYKKGDTVEISSHLYSNGAKVTLNNLYQDMKAVLLATDTDTGKVQELPMDNTGA 391 + ++ + KG+ +++L ++ ++Y M+A L+ D K +++PM N G Sbjct: 338 E-VKPEPVIKGNPATFTTYLQHQEGRLDDKDVYASMQAELIVNDLVGKKEEKVPMKNLGD 396 Query: 392 VFKGSFEIAESHNYELKVRAEESSFYRES 420 F + + YE K+ FYRE+ Sbjct: 397 SFTVDYVFPHTGKYEWKIFMNGPDFYRET 425 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.312 0.131 0.352 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,125,956,916 Number of extensions: 126352370 Number of successful extensions: 302260 Number of sequences better than 1.0e-05: 73 Number of HSP's gapped: 302462 Number of HSP's successfully gapped: 73 Length of query: 592 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 450 Effective length of database: 1,722,912,073 Effective search space: 775310432850 Effective search space used: 775310432850 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 134 (56.2 bits)