BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0188.0094.p (232 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KKJ6.1 B3KKJ6_9BACI 2-C-methyl-D-erythritol 4-phosphate cytidy... 311 3e-83 B1DK02.1 B1DK02_9BACL 2-C-methyl-D-erythritol 4-phosphate cytidy... 278 4e-73 B7GJ42.1 B7GJ42_ANOFW 2-C-methyl-D-erythritol 4-phosphate cytidy... 211 5e-53 A6TWL0.1 ISPD_ALKMQ 2-C-methyl-D-erythritol 4-phosphate cytidyly... 210 9e-53 B8G1T8.1 B8G1T8_DESHD 2-C-methyl-D-erythritol 4-phosphate cytidy... 208 3e-52 >B3KKJ6.1 B3KKJ6_9BACI 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase EC=2.7.7.60 Length = 231 Score = 311 bits (797), Expect = 3e-83, Method: Compositional matrix adjust. Identities = 151/229 (65%), Positives = 180/229 (78%), Gaps = 1/229 (0%) Query: 1 MSNSVGAVIVAAGRGTRMGTVESKQYLLLQGKPIIVHTLEVFQRHPLISEIVLVTGKEDV 60 MSN GAVIVAAG+GTRMGT ESKQYL+L GKPIIVHTLE F R P + EIVLVTG EDV Sbjct: 1 MSN-FGAVIVAAGKGTRMGTRESKQYLVLDGKPIIVHTLEAFSRIPWLQEIVLVTGMEDV 59 Query: 61 DRCQEWVKAYRLDKVVSVVTGGSERQHSVHLGLRHLKTTWVMVHDGVRPFVQINEITACY 120 RCQ WV+ Y L KV +V+ GGSERQ SV+ G++ + + WVM+HDGVRPFV EI AC Sbjct: 60 PRCQSWVQEYGLGKVSTVIPGGSERQQSVYQGIKQISSEWVMIHDGVRPFVTQEEIEACR 119 Query: 121 EHAREIGASVLAVPVKDTIKQVDKDGKVLSTPDRRSLWAIQTPQTFRLSELLVAYESAER 180 + A GASVL VPVKDTIKQV+ G + TPDR+SLWA+QTPQ FRLS+LL A+E+A + Sbjct: 120 DAAIREGASVLGVPVKDTIKQVNGKGLITGTPDRQSLWAVQTPQAFRLSDLLSAHEAAAK 179 Query: 181 DGFLGTDDSSLAERSGIPVAVVEGSYANIKITTPEDLDFAEFTQRSRGE 229 +GF GTDD+ L ER+G PV VVEG Y+NIKITTPEDL++A F Q+ +GE Sbjct: 180 EGFAGTDDAMLMERAGHPVTVVEGKYSNIKITTPEDLEYAAFLQKRKGE 228 >B1DK02.1 B1DK02_9BACL 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase EC=2.7.7.60 Length = 236 Score = 278 bits (710), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 140/229 (61%), Positives = 165/229 (72%), Gaps = 2/229 (0%) Query: 1 MSNSVGAVIVAAGRGTRMGTVESKQYLLLQGKPIIVHTLEVFQRHPLISEIVLVTGKEDV 60 M+ GAV+VAAGRG+RMGT ESKQYL L GKPI+VHTLE+FQ I++I LV G EDV Sbjct: 1 MNAHWGAVVVAAGRGSRMGTAESKQYLPLHGKPILVHTLELFQAMDEIADIALVVGAEDV 60 Query: 61 DRCQEWVKAYRLDKVVSVVTGGSERQHSVHLGLRHLKTT--WVMVHDGVRPFVQINEITA 118 +RC V+ Y+L KV +VV GGSERQHSV G++ L WVMVHDGVRP V I A Sbjct: 61 ERCTGLVEEYKLGKVTAVVAGGSERQHSVFAGIKALSPAAEWVMVHDGVRPLVTQKAIRA 120 Query: 119 CYEHAREIGASVLAVPVKDTIKQVDKDGKVLSTPDRRSLWAIQTPQTFRLSELLVAYESA 178 C A + GA+VLAVPVKDTIKQVD G ++STPDRRSLWAIQTPQ FR L A+E A Sbjct: 121 CCGKAEQNGAAVLAVPVKDTIKQVDDTGLIVSTPDRRSLWAIQTPQAFRRDLLTAAHERA 180 Query: 179 ERDGFLGTDDSSLAERSGIPVAVVEGSYANIKITTPEDLDFAEFTQRSR 227 + FLGTDD+ + ER+G PV + EG Y NIKITTP+DL +AEF R Sbjct: 181 AEEHFLGTDDAMVVERTGAPVVIAEGDYTNIKITTPDDLPWAEFLLEKR 229 >B7GJ42.1 B7GJ42_ANOFW 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase EC=2.7.7.60 Length = 240 Score = 211 bits (536), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 109/223 (48%), Positives = 154/223 (69%), Gaps = 2/223 (0%) Query: 8 VIVAAGRGTRMGTVESKQYLLLQGKPIIVHTLEVFQRHPLISEIVLVTGKEDVDRCQEWV 67 VI AAG+G RM +KQ++ ++G P+I+HTL VF+R IVLV ++ ++ + Sbjct: 18 VIPAAGQGKRMNAGINKQFIEIEGIPVIIHTLRVFERDDFCQGIVLVINDQEREQFVHML 77 Query: 68 KAYRLDKVVSVVTGGSERQHSVHLGLRHLKTTW-VMVHDGVRPFVQINEITACYEHAREI 126 + +++ KV ++V+GG ERQ SV+ GL+ + V++HDG RPFV I +I + +E Sbjct: 78 RCFKIKKVNALVSGGEERQQSVYNGLKAVNDGHIVLIHDGARPFVTIKKIHELVQATKET 137 Query: 127 GASVLAVPVKDTIKQVDKDGKVLSTPDRRSLWAIQTPQTFRLSELLVAYESAERDGFLGT 186 GA+VLAVPVKDT+KQV DG + T DR SLWA+QTPQ F +S +L A+E A+++ F+GT Sbjct: 138 GAAVLAVPVKDTMKQV-IDGHIEKTVDRSSLWAVQTPQAFSMSIILDAHERAKQEQFVGT 196 Query: 187 DDSSLAERSGIPVAVVEGSYANIKITTPEDLDFAEFTQRSRGE 229 DD+SL ER G V +VEG Y NIK+TTPEDL FAE R+RG+ Sbjct: 197 DDASLVERIGHRVVIVEGEYTNIKLTTPEDLLFAEAILRARGD 239 >A6TWL0.1 ISPD_ALKMQ 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase EC=2.7.7.60 Length = 241 Score = 210 bits (534), Expect = 9e-53, Method: Compositional matrix adjust. Identities = 114/234 (48%), Positives = 154/234 (65%), Gaps = 5/234 (2%) Query: 1 MSNSVGAVIVAAGRGTRMGTVESKQYLLLQGKPIIVHTLEVFQRHPLISEIVLVTGKEDV 60 +++ V ++VAAG+G RMG +KQY++L+ KPI+ HTL VF++H I+EI+LV + Sbjct: 3 VASKVTVIVVAAGKGKRMGRSYNKQYIMLENKPILYHTLAVFEKHSEINEIILVVASGEE 62 Query: 61 DRCQ-EWVKAYRLDKVVSVVTGGSERQHSVHLGLRHLKTTW--VMVHDGVRPFVQINEIT 117 + CQ + +K Y L KV VV GGSER++SV GL L+ V+VHDG RPF+ IT Sbjct: 63 EYCQGQIIKKYGLKKVRKVVAGGSERRNSVKNGLEELEEACEVVLVHDGARPFITKEVIT 122 Query: 118 ACYEHAREIGASVLAVPVKDTIKQVDKDGKVLSTPDRRSLWAIQTPQTFRLSELLVAYES 177 E A E GA ++AVPVKDTIK+V++ +V+ TP+R+ LWA+QTPQ FR L AY+ Sbjct: 123 KSIEVAYEEGAVIVAVPVKDTIKRVNEKMEVVETPERQQLWAVQTPQVFRSGILKRAYKE 182 Query: 178 AERDGFLGTDDSSLAERSGIPVAVVEGSYANIKITTPEDLDFAE--FTQRSRGE 229 AE +GTDD+ L E +G V VV G Y NIK+TTPEDL + QR GE Sbjct: 183 AEDFERVGTDDAVLVEAAGYTVKVVLGIYENIKVTTPEDLIIGQGILNQRKDGE 236 >B8G1T8.1 B8G1T8_DESHD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase EC=2.7.7.60 Length = 242 Score = 208 bits (530), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 108/219 (49%), Positives = 144/219 (65%), Gaps = 2/219 (0%) Query: 5 VGAVIVAAGRGTRMGTVESKQYLLLQGKPIIVHTLEVFQRHPLISEIVLVTGKEDVDRCQ 64 +G +I AAG+G RMG +KQ+L LQG+P++ HTL +F+R ++EIV+V+ KED +R Sbjct: 4 LGVIIPAAGQGKRMGASVNKQFLPLQGRPLLAHTLSLFERSGAVAEIVIVSAKEDRERIA 63 Query: 65 EWVKAYRLDKVVSVVTGGSERQHSVHLGLRHLKTTW--VMVHDGVRPFVQINEITACYEH 122 E V+ KV ++V GG ERQ SV G++ L + V VHDG RP + E+ + Sbjct: 64 ELVRTEGFQKVSAIVLGGEERQESVFAGVKALSSLIQRVAVHDGARPLLTCLELNRFFTE 123 Query: 123 AREIGASVLAVPVKDTIKQVDKDGKVLSTPDRRSLWAIQTPQTFRLSELLVAYESAERDG 182 A + GA+++AVPVKDTIK+VD GKVL TP R +L A+QTPQ F S L A+ A G Sbjct: 124 AEKFGAAIMAVPVKDTIKRVDAQGKVLETPPRETLRAVQTPQVFARSLLEEAHHKAREAG 183 Query: 183 FLGTDDSSLAERSGIPVAVVEGSYANIKITTPEDLDFAE 221 +L TDD++L E G PV + GS NIKITTPEDLD AE Sbjct: 184 YLTTDDAALIEWLGHPVQTLMGSLENIKITTPEDLDLAE 222 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.134 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,372,225,610 Number of extensions: 54534819 Number of successful extensions: 142043 Number of sequences better than 1.0e-05: 1438 Number of HSP's gapped: 138366 Number of HSP's successfully gapped: 1440 Length of query: 232 Length of database: 3,060,696,203 Length adjustment: 131 Effective length of query: 101 Effective length of database: 1,826,543,238 Effective search space: 184480867038 Effective search space used: 184480867038 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 129 (54.3 bits)