BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0188.0067.p (221 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A9NE93.1 A9NE93_ACHLI Transcriptional regulator, Crp/Fnr family 142 2e-32 A8U8V8.1 A8U8V8_9LACT Transcription regulator 127 7e-28 C0WNJ4.1 C0WNJ4_LACBU CRP/FNR family transcriptional regulator 127 9e-28 C2CZN1.1 C2CZN1_LACBR CRP/FNR family transcriptional regulator 127 9e-28 C0XJS3.1 C0XJS3_LACHI CRP/FNR family transcriptional regulator 126 1e-27 >A9NE93.1 A9NE93_ACHLI Transcriptional regulator, Crp/Fnr family Length = 231 Score = 142 bits (358), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 75/218 (34%), Positives = 133/218 (61%), Gaps = 8/218 (3%) Query: 1 VPVFESLSDKELEMIEAIIESHHYNRGQQVFREGEESDSLFVVKNGLIKLTQSNEEGKQH 60 VP+F L EL I +I+S +++G+ +F GE+SD+L++V++G IK+ +E K+H Sbjct: 16 VPIFNHLELDELTKITELIKSKSFDKGELIFSYGEKSDTLYIVRSGQIKMYYLSENAKEH 75 Query: 61 VVRYLFPGDYFGQFALLHHKRNNFTAEIVESGRVCRLRRKDFLPLLEQNASLAFSFLMSM 120 ++R LFPGD+ G+ ++ ++NN AE + VC ++++D L+E + + + Sbjct: 76 ILRMLFPGDFIGELSIFLDEKNNAYAEAITPVEVCMIKKEDISKLMEIYPKIGLKIIGEL 135 Query: 121 SEQLQQAEETAGVMHMFEVETRLARLLVKLTYSNKTEPFSPTRNQVIELPSAKKEIAAMI 180 +++L+++E+ A + +VE R+ +++L SN EP P IELP KK++A+ + Sbjct: 136 TQRLKKSEKQASWIATEQVEKRILLYMLELYDSN--EPLKP-----IELPMTKKDLASFL 188 Query: 181 GTTAETLSRKLHKLE-AGNIIAVRKRSVEIIDMEALCQ 217 GTT ETLSRKL LE G I + + ++I+ M+ L + Sbjct: 189 GTTPETLSRKLAYLEDLGMIHQLSNKQIKIVKMDLLLE 226 >A8U8V8.1 A8U8V8_9LACT Transcription regulator Length = 232 Score = 127 bits (319), Expect = 7e-28, Method: Compositional matrix adjust. Identities = 66/200 (33%), Positives = 119/200 (59%), Gaps = 7/200 (3%) Query: 1 VPVFESLSDKELEMIEAIIESHHYNRGQQVFREGEESDSLFVVKNGLIKLTQSNEEGKQH 60 +P+F+SL+ + + I ++I+S HY+RG+ ++R GE +DSL+V+++G I++ + ++ GK+ Sbjct: 26 IPLFQSLAPIQKKRIHSLIQSKHYSRGETIYRPGETADSLYVLRSGKIRVYRLSDSGKEQ 85 Query: 61 VVRYLFPGDYFGQFALLHHKRNNFTAEIVESGRVCRLRRKDFLPLLEQNASLAFSFLMSM 120 ++R ++PG++ G+ AL E + +C ++ DF LL Q +A L ++ Sbjct: 86 LIRIVYPGEFTGELALFKKGIYEAFTEALTDCSICAIKHTDFRELLLQYPLIAVEMLATI 145 Query: 121 SEQLQQAEETAGVMHMFEVETRLARLLVKLTYSNKTEPFSPTRNQVIELPSAKKEIAAMI 180 S +L +E+ V RL L+ L S + EP +IEL AKK++A+ + Sbjct: 146 SNRLGMSEQQTAWATTETVRNRLLHFLISLVDSKENEP-------IIELKMAKKDLASYL 198 Query: 181 GTTAETLSRKLHKLEAGNII 200 GTT+E+LSR+L LE ++I Sbjct: 199 GTTSESLSRELAHLEKEHVI 218 >C0WNJ4.1 C0WNJ4_LACBU CRP/FNR family transcriptional regulator Length = 228 Score = 127 bits (318), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 69/218 (31%), Positives = 120/218 (55%), Gaps = 8/218 (3%) Query: 1 VPVFESLSDKELEMIEAIIESHHYNRGQQVFREGEESDSLFVVKNGLIKLTQSNEEGKQH 60 VP+F+SL E + + ++ H Y +G ++ G++ ++++G +KL+Q +E GK+ Sbjct: 18 VPIFKSLPLDEKKAVAGLVVQHQYPKGTIIYLAGDQVGHFMILEHGQVKLSQISESGKEQ 77 Query: 61 VVRYLFPGDYFGQFALLHHKRNNFTAEIVESGRVCRLRRKDFLPLLEQNASLAFSFLMSM 120 +++ + PGD+ G+ AL H + N TA + VC++ + F LL+ + LA + L +M Sbjct: 78 LLKVMQPGDFDGEAALFSHDQRNVTATALVDSNVCQIDQDAFQSLLKSSPQLAVNLLTTM 137 Query: 121 SEQLQQAEETAGVMHMFEVETRLARLLVKLTYSNKTEPFSPTRNQVIELPSAKKEIAAMI 180 S+Q+ +E V +V +LA+ L++ + S F +LP KK+IA I Sbjct: 138 SQQINNLQEEKTVSSTSDVAGQLAKYLLETSASLHESSF--------KLPLKKKDIATFI 189 Query: 181 GTTAETLSRKLHKLEAGNIIAVRKRSVEIIDMEALCQI 218 GTT ET+SR +L A +I + VEI+D + L I Sbjct: 190 GTTPETISRTFKQLIADGVIKMTASLVEIVDQDRLTDI 227 >C2CZN1.1 C2CZN1_LACBR CRP/FNR family transcriptional regulator Length = 223 Score = 127 bits (318), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 69/218 (31%), Positives = 120/218 (55%), Gaps = 8/218 (3%) Query: 1 VPVFESLSDKELEMIEAIIESHHYNRGQQVFREGEESDSLFVVKNGLIKLTQSNEEGKQH 60 VP+F+SL E + + ++ H Y +G ++ G++ ++++G +KL+Q +E GK+ Sbjct: 13 VPIFKSLPLDEKKAVAGLVVQHQYPKGTIIYLAGDQVGHFMILEHGQVKLSQISESGKEQ 72 Query: 61 VVRYLFPGDYFGQFALLHHKRNNFTAEIVESGRVCRLRRKDFLPLLEQNASLAFSFLMSM 120 +++ + PGD+ G+ AL H + N TA + VC++ + F LL+ + LA + L +M Sbjct: 73 LLKVMQPGDFDGEAALFSHDQRNVTATALVDSNVCQIDQDAFQSLLKSSPQLAVNLLTTM 132 Query: 121 SEQLQQAEETAGVMHMFEVETRLARLLVKLTYSNKTEPFSPTRNQVIELPSAKKEIAAMI 180 S+Q+ +E V +V +LA+ L++ + S F +LP KK+IA I Sbjct: 133 SQQINNLQEEKTVSSTSDVAGQLAKYLLETSASLHESSF--------KLPLKKKDIATFI 184 Query: 181 GTTAETLSRKLHKLEAGNIIAVRKRSVEIIDMEALCQI 218 GTT ET+SR +L A +I + VEI+D + L I Sbjct: 185 GTTPETISRTFKQLIADGVIKMTASLVEIVDQDRLTDI 222 >C0XJS3.1 C0XJS3_LACHI CRP/FNR family transcriptional regulator Length = 228 Score = 126 bits (317), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 69/218 (31%), Positives = 120/218 (55%), Gaps = 8/218 (3%) Query: 1 VPVFESLSDKELEMIEAIIESHHYNRGQQVFREGEESDSLFVVKNGLIKLTQSNEEGKQH 60 VP+F+SL E + + ++ H Y +G ++ G++ ++++G +KL+Q +E GK+ Sbjct: 18 VPIFKSLPLDEKKAVAGLVVQHQYPKGTIIYLAGDQVGHFMILEHGQVKLSQISESGKEQ 77 Query: 61 VVRYLFPGDYFGQFALLHHKRNNFTAEIVESGRVCRLRRKDFLPLLEQNASLAFSFLMSM 120 +++ + PGD+ G+ AL H + N TA + VC++ + F LL+ + LA + L +M Sbjct: 78 LLKVMQPGDFDGEAALFSHDQRNVTATALVDSNVCQIDQGAFQSLLKSSPQLAVNLLTTM 137 Query: 121 SEQLQQAEETAGVMHMFEVETRLARLLVKLTYSNKTEPFSPTRNQVIELPSAKKEIAAMI 180 S+Q+ +E V +V +LA+ L++ + S F +LP KK+IA I Sbjct: 138 SQQINNLQEEKTVSSTSDVAGQLAKYLLETSASLHESSF--------KLPLKKKDIATFI 189 Query: 181 GTTAETLSRKLHKLEAGNIIAVRKRSVEIIDMEALCQI 218 GTT ET+SR +L A +I + VEI+D + L I Sbjct: 190 GTTPETISRTFKQLIADGVIKMTASLVEIVDQDRLTDI 227 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.134 0.369 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,179,766,847 Number of extensions: 44788684 Number of successful extensions: 126681 Number of sequences better than 1.0e-05: 2598 Number of HSP's gapped: 126193 Number of HSP's successfully gapped: 2598 Length of query: 221 Length of database: 3,060,696,203 Length adjustment: 131 Effective length of query: 90 Effective length of database: 1,826,543,238 Effective search space: 164388891420 Effective search space used: 164388891420 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 128 (53.9 bits)