BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0188.0043.p (250 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KLM0.1 B3KLM0_9BACI Methionine aminopeptidase EC=3.4.11.18 459 e-128 B1DJV0.1 B1DJV0_9BACL Methionine aminopeptidase EC=3.4.11.18 419 e-115 C4KZM4.1 C4KZM4_EXISA Methionine aminopeptidase, type I 374 e-102 C0ZIK2.1 C0ZIK2_BREBN Methionine aminopeptidase EC=3.4.11.18 369 e-100 B7GJ89.1 B7GJ89_ANOFW Methionine aminopeptidase EC=3.4.11.18 366 1e-99 >B3KLM0.1 B3KLM0_9BACI Methionine aminopeptidase EC=3.4.11.18 Length = 250 Score = 459 bits (1182), Expect = e-128, Method: Compositional matrix adjust. Identities = 217/248 (87%), Positives = 235/248 (94%) Query: 1 MIICKSEQELAFMREAGRIVAESHRLIAEAIEPGITTGELDRIADQYIRSQGAVPSFKGY 60 MIICKSE EL+ MREAGRIVAE H+L+A +EPGITTGELD +AD++IRSQGAVPSFKGY Sbjct: 1 MIICKSETELSLMREAGRIVAECHKLLAAHVEPGITTGELDLMADKFIRSQGAVPSFKGY 60 Query: 61 NGFPASICASVNEQLVHGFPGKRKLIEGDIVTLDIGAEYRGYHGDSAWTYGVGSISEEAQ 120 NGFP+SICASVNE+LVHGFPGKRKLIEGDIVT DIGA+Y+GYHGDSAWTY VG ISEEAQ Sbjct: 61 NGFPSSICASVNEELVHGFPGKRKLIEGDIVTFDIGAQYQGYHGDSAWTYAVGEISEEAQ 120 Query: 121 RLLDVTEGSLYAGLALVKPDVRLFTISHAIQQYIEDAGFSVVREYVGHGIGAELHEEPQI 180 RLLDVTEGSLYAGLALVKPDVRLFTISHAIQ++IEDAGFSVVREYVGHG+G +LHE+PQI Sbjct: 121 RLLDVTEGSLYAGLALVKPDVRLFTISHAIQRHIEDAGFSVVREYVGHGVGTDLHEDPQI 180 Query: 181 PNYGIADRGPRLKPGMVLAIEPMVNAGDRYVRTLEDNWTVVTVDGSLCAHFEHTVAVTPD 240 PNYGI DRGPRLKPGMVLAIEPMVNAG R+V+TLEDNWTVVTVDGSLCAHFEHTVAVTPD Sbjct: 181 PNYGIPDRGPRLKPGMVLAIEPMVNAGKRHVKTLEDNWTVVTVDGSLCAHFEHTVAVTPD 240 Query: 241 GMEIFTKL 248 GMEI TKL Sbjct: 241 GMEILTKL 248 >B1DJV0.1 B1DJV0_9BACL Methionine aminopeptidase EC=3.4.11.18 Length = 252 Score = 419 bits (1077), Expect = e-115, Method: Compositional matrix adjust. Identities = 194/248 (78%), Positives = 225/248 (90%) Query: 1 MIICKSEQELAFMREAGRIVAESHRLIAEAIEPGITTGELDRIADQYIRSQGAVPSFKGY 60 MIICKS+ EL +MREAGRIVAE+HR++AEA++PG+TT ELD++A+ YIRSQGA PSFKGY Sbjct: 1 MIICKSDSELRYMREAGRIVAETHRIMAEAVKPGVTTQELDQLAEAYIRSQGAEPSFKGY 60 Query: 61 NGFPASICASVNEQLVHGFPGKRKLIEGDIVTLDIGAEYRGYHGDSAWTYGVGSISEEAQ 120 NGFPASICASVN++LVHGFPG RKL EGDI+++DIGA+Y+GYHGDSAWTY VG++S+E + Sbjct: 61 NGFPASICASVNDELVHGFPGPRKLNEGDIISIDIGAQYKGYHGDSAWTYPVGNVSDEVK 120 Query: 121 RLLDVTEGSLYAGLALVKPDVRLFTISHAIQQYIEDAGFSVVREYVGHGIGAELHEEPQI 180 RLL+VTE SLYAG+ L++PDVRLFTISHA+QQ E AGFS+VRE+VGHGIG +LHEEPQI Sbjct: 121 RLLEVTEESLYAGINLIRPDVRLFTISHAVQQVAEAAGFSIVREFVGHGIGKDLHEEPQI 180 Query: 181 PNYGIADRGPRLKPGMVLAIEPMVNAGDRYVRTLEDNWTVVTVDGSLCAHFEHTVAVTPD 240 PNYGI DRGPRLKPGMVL IEPMVN G+RYVRTLEDNWTVVT DGS CAHFEHTVAVT D Sbjct: 181 PNYGIPDRGPRLKPGMVLCIEPMVNIGERYVRTLEDNWTVVTEDGSWCAHFEHTVAVTED 240 Query: 241 GMEIFTKL 248 G EI TKL Sbjct: 241 GFEILTKL 248 >C4KZM4.1 C4KZM4_EXISA Methionine aminopeptidase, type I Length = 252 Score = 374 bits (961), Expect = e-102, Method: Compositional matrix adjust. Identities = 179/250 (71%), Positives = 206/250 (82%) Query: 1 MIICKSEQELAFMREAGRIVAESHRLIAEAIEPGITTGELDRIADQYIRSQGAVPSFKGY 60 MII K+ +E+A MREAG+IVA +H+++ + I+PGITT ELDRIA+ YIRSQGA PSFKGY Sbjct: 1 MIITKTPREIAIMREAGQIVARTHQVLKQHIKPGITTLELDRIAEDYIRSQGATPSFKGY 60 Query: 61 NGFPASICASVNEQLVHGFPGKRKLIEGDIVTLDIGAEYRGYHGDSAWTYGVGSISEEAQ 120 NGF S+CASVNE+LVHG PGKR L +GDI+++DIGA Y GYHGDSAWTY VG+ISEE Q Sbjct: 61 NGFTGSVCASVNEELVHGIPGKRVLKDGDIISIDIGAYYNGYHGDSAWTYPVGTISEETQ 120 Query: 121 RLLDVTEGSLYAGLALVKPDVRLFTISHAIQQYIEDAGFSVVREYVGHGIGAELHEEPQI 180 RLLDVTE SLY GL K RL ISHAIQ Y+E FSVVREYVGHG+G LHEEPQI Sbjct: 121 RLLDVTEESLYKGLEHAKAGGRLTDISHAIQAYVESNDFSVVREYVGHGVGQNLHEEPQI 180 Query: 181 PNYGIADRGPRLKPGMVLAIEPMVNAGDRYVRTLEDNWTVVTVDGSLCAHFEHTVAVTPD 240 P+YG +GPRLK GM LAIEPMVNAG RYVRTL DNWTVVTVDGS+CAHFEHT+A+T D Sbjct: 181 PHYGPPGKGPRLKTGMTLAIEPMVNAGQRYVRTLADNWTVVTVDGSMCAHFEHTIAITDD 240 Query: 241 GMEIFTKLNA 250 G EI TKL++ Sbjct: 241 GYEILTKLDS 250 >C0ZIK2.1 C0ZIK2_BREBN Methionine aminopeptidase EC=3.4.11.18 Length = 248 Score = 369 bits (946), Expect = e-100, Method: Compositional matrix adjust. Identities = 176/247 (71%), Positives = 204/247 (82%) Query: 1 MIICKSEQELAFMREAGRIVAESHRLIAEAIEPGITTGELDRIADQYIRSQGAVPSFKGY 60 MII KS+ EL MREAGRIVA +H+ +A+AI+PG+TT +LD IA+ +IRS GA+PSFKGY Sbjct: 1 MIILKSKAELEVMREAGRIVALTHQELAKAIKPGVTTKQLDEIAETFIRSMGAIPSFKGY 60 Query: 61 NGFPASICASVNEQLVHGFPGKRKLIEGDIVTLDIGAEYRGYHGDSAWTYGVGSISEEAQ 120 GFP SICASVNE+LVHG PGKR L EGDI+++DIGA+++GYHGDSAWTY VG IS E Q Sbjct: 61 GGFPGSICASVNEELVHGIPGKRALQEGDIISIDIGAQFQGYHGDSAWTYPVGKISTENQ 120 Query: 121 RLLDVTEGSLYAGLALVKPDVRLFTISHAIQQYIEDAGFSVVREYVGHGIGAELHEEPQI 180 +LL VTE SLY GL P RL ISHAIQ + E A F++VREYVGHGIG LHE+PQ+ Sbjct: 121 KLLRVTEESLYKGLEKAVPGGRLSDISHAIQVHAEAADFTLVREYVGHGIGQNLHEDPQV 180 Query: 181 PNYGIADRGPRLKPGMVLAIEPMVNAGDRYVRTLEDNWTVVTVDGSLCAHFEHTVAVTPD 240 PNYG DRGPRLKPGMVLAIEPMVNAG+RYVRTLEDNWTVVTVD CAHFEHT+A+T D Sbjct: 181 PNYGPPDRGPRLKPGMVLAIEPMVNAGERYVRTLEDNWTVVTVDRKTCAHFEHTIAITED 240 Query: 241 GMEIFTK 247 G EIFT+ Sbjct: 241 GYEIFTR 247 >B7GJ89.1 B7GJ89_ANOFW Methionine aminopeptidase EC=3.4.11.18 Length = 248 Score = 366 bits (939), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 175/248 (70%), Positives = 201/248 (81%) Query: 1 MIICKSEQELAFMREAGRIVAESHRLIAEAIEPGITTGELDRIADQYIRSQGAVPSFKGY 60 MIICK+ +E+ MREAGRIVA +H+ + + IEPGITT ELD IA+ +IR A+PSFKGY Sbjct: 1 MIICKTPREIEIMREAGRIVALTHQELQKYIEPGITTRELDHIAETFIRKHDAIPSFKGY 60 Query: 61 NGFPASICASVNEQLVHGFPGKRKLIEGDIVTLDIGAEYRGYHGDSAWTYGVGSISEEAQ 120 NGF SIC SVNE+LVHG PG R L EGDI+++DIGA+Y GYHGDSAWTY VG ISEEA+ Sbjct: 61 NGFQGSICTSVNEELVHGVPGDRVLREGDIISIDIGAKYNGYHGDSAWTYPVGVISEEAK 120 Query: 121 RLLDVTEGSLYAGLALVKPDVRLFTISHAIQQYIEDAGFSVVREYVGHGIGAELHEEPQI 180 +LL+VTE SLY GL KP RL ISHAIQ Y+E FSVVREYVGHGIG +LHE+PQI Sbjct: 121 KLLEVTEQSLYRGLEEAKPGARLTNISHAIQTYVEAHNFSVVREYVGHGIGQDLHEDPQI 180 Query: 181 PNYGIADRGPRLKPGMVLAIEPMVNAGDRYVRTLEDNWTVVTVDGSLCAHFEHTVAVTPD 240 P+YG ++GPRLKPGMVL IEPMVNAG RYVRTLEDNWTVVTVDG LCAHFEHT+A+T Sbjct: 181 PHYGPPNKGPRLKPGMVLCIEPMVNAGTRYVRTLEDNWTVVTVDGKLCAHFEHTIAITET 240 Query: 241 GMEIFTKL 248 G EI T L Sbjct: 241 GYEILTTL 248 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.138 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,573,858,116 Number of extensions: 68174866 Number of successful extensions: 168197 Number of sequences better than 1.0e-05: 4432 Number of HSP's gapped: 161502 Number of HSP's successfully gapped: 4444 Length of query: 250 Length of database: 3,060,696,203 Length adjustment: 132 Effective length of query: 118 Effective length of database: 1,817,122,223 Effective search space: 214420422314 Effective search space used: 214420422314 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 129 (54.3 bits)