BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0184.0020.p (1501 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B8I5I7.1 B8I5I7_CLOCE Amino acid adenylation domain protein 1523 0.0 B8I967.1 B8I967_CLOCE Amino acid adenylation domain protein 1432 0.0 C1FRI4.1 C1FRI4_CLOBJ Nonribosomal peptide synthetase subunit 1384 0.0 A9VQN1.1 A9VQN1_BACWK Amino acid adenylation domain 1369 0.0 C2SIR0.1 C2SIR0_BACCE Putative uncharacterized protein 1367 0.0 >B8I5I7.1 B8I5I7_CLOCE Amino acid adenylation domain protein Length = 1490 Score = 1523 bits (3944), Expect = 0.0, Method: Compositional matrix adjust. Identities = 752/1511 (49%), Positives = 1034/1511 (68%), Gaps = 31/1511 (2%) Query: 1 MEELLHMKPSIFYPLTHPQQRIWSIEQIYPQTPLHNIGGTIRIKGPVQFPVLEKAIDLFI 60 M+ + + YPLTHPQ+RIW +E+IYP T L+NIGG +R+KG + F +LEKAI+L I Sbjct: 1 MDGICFSNDRVLYPLTHPQKRIWYMEKIYPGTSLYNIGGPVRVKGTIDFSILEKAINLLI 60 Query: 61 QSHEALRLRIAAENGEPRQYIGHNNDFPLDFIDFSTCSEPEREFADWVESIAQKPFVLEN 120 + +E LRLR +NG+ +QY+ LD DF+ PE+EF WV+ A+KPF EN Sbjct: 61 KRNEGLRLRFIEKNGQVKQYVSDYEKIKLDLFDFTQYENPEKEFNKWVDKQAEKPFAKEN 120 Query: 121 ERLFYFAMFRVSDHENGYLAKFHHIVADGWSMNIMTDQISGIYTRLLRGERVEVQPG-PS 179 LFYFAMF++SD++NGYLAKFHHI+ADGWS+NIMT QI Y +L+ E ++ G S Sbjct: 121 RGLFYFAMFKLSDNDNGYLAKFHHIIADGWSINIMTQQICDSYMKLINEEEIDNDSGGES 180 Query: 180 YLEYRDEEQAYLASERFHKNRTFWTGKYRALPDSFLNASSDRLAGNRKTYEWSPELSARI 239 Y+ Y D E+ Y++S+RF KN+ FW K++ LP+ +SD + G RKT+E P +S I Sbjct: 181 YIGYIDIEKKYISSDRFQKNKAFWNEKFKELPEVVTTKNSDSIEGKRKTFELEPSISTGI 240 Query: 240 KGLAAAHNCSLNTFFITAYLLYTHKITGQDDLVVGTPVLNRSGRRQKSTFGMYTSTMPFR 299 +A + SLN FF+T YL+Y +K + Q D+++GTPVLNRSG+++KS FGM+TSTMPFR Sbjct: 241 NSFSAENKYSLNAFFVTLYLIYLYKTSQQKDIIIGTPVLNRSGKKEKSMFGMFTSTMPFR 300 Query: 300 YVIDGSSSVLDTMTRINSELMACYFHQRYPYDRLIQELELKKKGLDQLFNVCVNYYNTKL 359 Y ID +SS+ +TM++++ +L CYF+Q+YPY+ L+Q+LELKKKG LFNVC+NYYNTKL Sbjct: 301 YCIDNNSSITETMSKVSEQLKECYFNQKYPYEFLVQDLELKKKGYGSLFNVCINYYNTKL 360 Query: 360 GTEINGYPVDSVEFYSGQQMYSMQLVLKEWTGSGSITASFDYKLNDFTDEQIDDMYGHLT 419 +E+N +P+++VEFY+G+Q YS QLV+KEW S S+ FDYK+ND+TDEQI +MY L Sbjct: 361 NSELNDFPIENVEFYNGKQTYSFQLVIKEW--SESLILDFDYKVNDYTDEQIAEMYIRLL 418 Query: 420 TLITQMVSDPEAQISQISILSKEEWTERVHSYNATQAAYPHDKTICQLFEEQAEKTPDAI 479 LI Q++ +P +I +S+LS+EE + V+ +NATQ YP++KTI QLFE++ E++ D Sbjct: 419 NLINQIIKNPSKKIGNLSLLSEEENNKIVYLFNATQTEYPNEKTIYQLFEDEVERSADKP 478 Query: 480 AVTCKNEHLTYKQLNGKANQLARFLIEKGVGRETIVGLLTAHSLETVISVLGIGKAGGAF 539 AV + +TYK+LN KAN LA +LI++G+ RE IVGL T+HS+ETVI++LGI KAGGA+ Sbjct: 479 AVVFNSTEITYKELNEKANGLAGYLIKRGIKREKIVGLATSHSIETVIAILGILKAGGAY 538 Query: 540 LPIDPGNPAERLDYILQDAGAKFLLTNLSLVDECSFDGVIINLEEIKYDAYRTSNVKP-- 597 LPIDP P ER++Y+L+D+ A LLTN+ + +FDG II+L++ Y+++ V P Sbjct: 539 LPIDPTYPVERVNYMLEDSEACLLLTNVEIGKSLNFDGDIIDLKD--ESIYKSTAVNPGL 596 Query: 598 VSKPDDLVYVIYTSGSTGRPKGTMIEHRGLVNYICWAKKVYVKQTEEVFPLYSSLAFDLT 657 V++PDDL YVIYTSGSTGRPKG MIEHRGLVNYI WAKK+Y+K + EVFPLYSSLAFDLT Sbjct: 597 VNRPDDLAYVIYTSGSTGRPKGVMIEHRGLVNYIWWAKKMYIKDSVEVFPLYSSLAFDLT 656 Query: 658 VTSLFTPLISGGAIMVY--RDDEDEYVLFRILEENQATIVKLTPSHLSLLLDRDQLNSSV 715 VTS+FTPLISG I+VY +++EYVL+RI+ EN++T++KLTP+HLSLL D D S+V Sbjct: 657 VTSIFTPLISGSKIIVYDGNSEDEEYVLYRIMRENKSTVIKLTPAHLSLLKDMDNKKSTV 716 Query: 716 KSFIVGGENLKASLAKKIYDRFGGNVEIFNEYGPTETVVGCMIHSYAPDTDTRAAVPIGR 775 K FIVGG++LK L + IY+ FGGN+EI+NEYGPTETVVGCMIH Y DT +VPIG Sbjct: 717 KRFIVGGDDLKVKLVQAIYESFGGNIEIYNEYGPTETVVGCMIHKYDYSKDTGTSVPIGI 776 Query: 776 PADNVQIYLLDKSLAPVPVHAVGEIYIAGDGVARGYLNNPELTAEKFIDNPFAPGKRMYK 835 PA NVQ+Y+LD +L PVP GE+YI+GDGVARGYLN PE T E+FI NPF GKRMYK Sbjct: 777 PAKNVQVYILDGNLNPVPADTEGELYISGDGVARGYLNRPEQTRERFITNPFLKGKRMYK 836 Query: 836 TGDQGRFLRDGTLEYIGRADKQIKIRGYRVELEEIEKHLLQHTGITEAVVLNRQDKQQHA 895 TGD GR L++G +EY GR D Q+KI G+R+E EIE+ LL H G+ AVV++ QD+ Sbjct: 837 TGDSGRLLKNGKIEYAGRLDYQVKIHGHRIETGEIEECLLNHRGVGAAVVISLQDRNNEK 896 Query: 896 YLCAYIVSERRFAAHELKEYLKKQLPDYLIPLHFIEVQEIPLTVNGKVDTALLEEIAPPE 955 YLCAYIV++ + EL+E+L+ LPDY++PL+FI V +IPLTVNGK++ ALL P Sbjct: 897 YLCAYIVNKSEVSEQELREHLQGYLPDYMLPLYFINVDKIPLTVNGKINKALL----PKP 952 Query: 956 NADKT----YIQPRNEHEAQLIQVVGEVLRVDGAGVKHNFYHLGGDSIQAIRIASKMSQK 1011 N D T ++ R E+E +L+ + EVL ++ ++ NFY LGGDSI+AI+IASK++ Sbjct: 953 NEDSTEEEEFVPSRTENEKELVTAISEVLNLERVSIRQNFYRLGGDSIKAIQIASKLNDN 1012 Query: 1012 GFKLKVKDILSFPVLEEMAAFIEREQSEAVEQGAAEGGIPLTPILSYFFSQHFAKAGHYH 1071 GF+LKVKDI+S P++++MA IE+ V+ +G I TPI ++FF Q FA+ +Y+ Sbjct: 1013 GFRLKVKDIMSNPLIKDMALNIEKIGVGMVDTEPCKGSIRHTPITAWFFRQGFAEPSYYN 1072 Query: 1072 QSVMAVLKREIGLDTLEKALSALIRHHDSLRINCRSDNGGLFYNQEHYHTRPSIEEYDFS 1131 QSV+ LKR + L+ LIRHHD LR+N + LFYN ++ I+EYD S Sbjct: 1073 QSVLLELKRTYDVKALQTVFENLIRHHDILRVNYNKETEELFYNNDYLEQPFHIKEYDLS 1132 Query: 1132 DLSLPEQEARLGEAAQRLAASFDLQHSLLLKAAVFELGHVRKMLLI-AHHLVVDGVSWRI 1190 + +Q + + ++ L AS +L+ S+L+K VF L K LLI AHHL+VDGVSWRI Sbjct: 1133 ECKPYKQSEAIEKISEELKASLELEKSILIKVCVFWLSENEKFLLITAHHLIVDGVSWRI 1192 Query: 1191 ILEDMNTLLQQIHHGQEAALPLKTSSYQKWATALEASRETLGMKEEEYWNSVLQKHFTFS 1250 ILED+ T+L+Q+ + E LP KT SYQ WA L+ + +E + + + + Sbjct: 1193 ILEDIYTMLKQLSNSSEIVLPEKTHSYQIWAELLQVASNNSAELKERCKPGLCE--YCYP 1250 Query: 1251 ADHDRGADTLASCHTLISGLGQPETAALLSEANIPYNTEPHDLLLTSLLVTVKEWTGSRD 1310 D D+G D + T+ L ET LL +AN YNT +DLL+ +L T+ E T Sbjct: 1251 VDFDKGHDLMEFSSTVKGELTDEETRKLLLKANGAYNTNTNDLLIVALAKTISEKTKFNT 1310 Query: 1311 IVIELEGHGREDIDELVDVTRTVGWFTSLYPFGITLNGEALPGQIKQVKEERRRVPGNGI 1370 + +E+E HGR+++ + TRTVGWFT + F + + L IK +K + R N I Sbjct: 1311 VYLEIESHGRKELAGDFNFTRTVGWFTEMDVFRLEIEHGELSQVIKTIKNQLRE-NSNKI 1369 Query: 1371 GFGLLRQLGRIGDHRLRKYIRFNYLGEFTEDHGGGNLTLSGDQFQHNVSGDNHLTSVLDI 1430 L+ +K IRFNYLG+F + + + S +N +T+++DI Sbjct: 1370 DRSDLQ----------KKQIRFNYLGDFGTNFENDLFCIRYGDTGLDCSRNNVMTALIDI 1419 Query: 1431 NCFVIGGRLQLRLTYSRNKFLDMTMERFQTHWIRNLKLVLEHCSNTERKEYTPSDFDTVD 1490 N V+ RL++ + +S NKF +TME F +I NLK V+EHC N + E+T SDFDT+ Sbjct: 1420 NAIVVNDRLKIEVLFSDNKFKKVTMETFLISFINNLKQVIEHCCNRKTVEFTTSDFDTIG 1479 Query: 1491 ISQEELDSLFS 1501 ISQ ELDSLFS Sbjct: 1480 ISQTELDSLFS 1490 >B8I967.1 B8I967_CLOCE Amino acid adenylation domain protein Length = 1506 Score = 1432 bits (3708), Expect = 0.0, Method: Compositional matrix adjust. Identities = 696/1499 (46%), Positives = 996/1499 (66%), Gaps = 14/1499 (0%) Query: 11 IFYPLTHPQQRIWSIEQIYPQTPLHNIGGTIRIKGPVQFPVLEKAIDLFIQSHEALRLRI 70 I+Y LTHPQ+RIW IE IYP+ P+HNIGG + I + F LE+AI++FI H+ LR+RI Sbjct: 12 IYYSLTHPQKRIWYIENIYPEIPIHNIGGAVTINSHIDFDALEEAINIFISKHDGLRIRI 71 Query: 71 AAENGEPRQYIGHNNDFPLDFIDFSTCSEPER-EFADWVESIAQKPFVLENERLFYFAMF 129 +NG+P+QY+ LD+ D S+ E + E+ ++ +KPF L + LF+FA+F Sbjct: 72 VDKNGDPQQYVSEFKRTKLDYYDLSSYHEGAKAEYYRIADTEMKKPFKLLDNPLFFFALF 131 Query: 130 RVSDHENGYLAKFHHIVADGWSMNIMTDQISGIYTRLLRGERVEVQPGPSYLEYRDEEQA 189 ++ ++ +GY K HHI++DGWS+ ++T QI IYT L+ G ++ + SY++Y +E+ Sbjct: 132 KLDNNVSGYFIKLHHIISDGWSIELLTRQIMEIYTELIEGREIKQEKEQSYIDYIKQEKV 191 Query: 190 YLASERFHKNRTFWTGKYRALPDSFLNASSDRLAGNRKTYEWSPELSARIKGLAAAHNCS 249 YL SE+F KN+ FW K+ LP+ F SS+ AG R+ + + + +K A + CS Sbjct: 192 YLGSEKFIKNKNFWNNKFAELPEEFSIKSSNDTAGERQIFYIGKKKTELLKEFCAQNKCS 251 Query: 250 LNTFFITAYLLYTHKITGQDDLVVGTPVLNRSGRRQKSTFGMYTSTMPFRYVIDGSSSVL 309 L TFF + L+Y KIT Q+D+++GTPVLNRSG+++KS FGM+TSTMP R ++ S+ Sbjct: 252 LYTFFTSLLLIYLSKITLQEDIIIGTPVLNRSGKKEKSIFGMFTSTMPLRANVNQESTAA 311 Query: 310 DTMTRINSELMACYFHQRYPYDRLIQELELKKKGLDQLFNVCVNYYNTKLGTEINGYPVD 369 + + INSELM C+F+Q+YPYD L+++LELKKKGLD LF V +NYYNTK+ + + ++ Sbjct: 312 EFIRGINSELMDCFFNQKYPYDLLVKDLELKKKGLDSLFQVSINYYNTKMESRLYDASIE 371 Query: 370 SVEFYSGQQMYSMQLVLKEWTGSGSITASFDYKLNDFTDEQIDDMYGHLTTLITQMVSDP 429 ++EFYSG Q Y +QL++K+W +++ SFDYKL+++T EQI MY L L+ Q+VS+P Sbjct: 372 NMEFYSGHQSYPLQLIIKDWLEDSNLSLSFDYKLSEYTTEQIKYMYYRLDALLDQIVSNP 431 Query: 430 EAQISQISILSKEEWTERVHSYNATQAAYPHDKTICQLFEEQAEKTPDAIAVTCKNEHLT 489 +I + +++ EW V+ +N+ + YP +TI +LFEEQAE+TP+ AV + LT Sbjct: 432 SKKIFNLHLVNDSEWNWLVYGFNSVKGEYPSQRTIYELFEEQAERTPNKTAVIFDSIELT 491 Query: 490 YKQLNGKANQLARFLIEKGVGRETIVGLLTAHSLETVISVLGIGKAGGAFLPIDPGNPAE 549 YK+LN ++N LAR+L E GVGR+ IVGL++ HS VI +L I KAGGA+LPID PAE Sbjct: 492 YKELNERSNSLARYLRELGVGRDRIVGLMSTHSHYMVIGILAIIKAGGAYLPIDSTYPAE 551 Query: 550 RLDYILQDAGAKFLLTNLSLVDECSFDGVIINLEEIKYDAYRTSNVKPVSKPDDLVYVIY 609 R+++I++D+G LLT+ ++ E +++G IINL++ + N++ ++K DLVYVIY Sbjct: 552 RIEFIVKDSGTSILLTDNTIPKETNYNGHIINLKDENLYKGQVCNLEKINKTTDLVYVIY 611 Query: 610 TSGSTGRPKGTMIEHRGLVNYICWAKKVYVKQTEEVFPLYSSLAFDLTVTSLFTPLISGG 669 TSGSTG PKG M+EHRGLVNYI WAKK+YV+ +EVFPLY+SL+FDLTVTS+FTPLISG Sbjct: 612 TSGSTGAPKGVMVEHRGLVNYIWWAKKMYVRNEKEVFPLYTSLSFDLTVTSIFTPLISGN 671 Query: 670 AIMVYRDDEDEYVLFRILEENQATIVKLTPSHLSLLLDRDQLNSSVKSFIVGGENLKASL 729 I+VY DD E++L RIL EN+ +I+KLTP HLS++ D + NSSVK FIVGGE+LK +L Sbjct: 672 TIVVYYDDGTEFILLRILRENKVSIIKLTPVHLSIIKDMNNDNSSVKRFIVGGEDLKVAL 731 Query: 730 AKKIYDRFGGNVEIFNEYGPTETVVGCMIHSYAPDTDTRAAVPIGRPADNVQIYLLDKSL 789 A IY FGG++EIFNEYGPTETVVGCMIH Y D +VPIG PADN+QIY+LDK+L Sbjct: 732 AHSIYKSFGGDIEIFNEYGPTETVVGCMIHKYDVKNDLGVSVPIGIPADNIQIYILDKNL 791 Query: 790 APVPVHAVGEIYIAGDGVARGYLNNPELTAEKFIDNPFAPGKRMYKTGDQGRFLRDGTLE 849 PVPV +GE+Y++G GV RGYLN ELT E+F+DNPF G +MYKTGD + L G + Sbjct: 792 NPVPVETIGELYVSGAGVTRGYLNREELTKERFVDNPFIKGSKMYKTGDLAKHLHGGEIV 851 Query: 850 YIGRADKQIKIRGYRVELEEIEKHLLQHTGITEAVVLNRQDKQQHAYLCAYIVSERRFAA 909 Y+GR+D Q+K+RGYR+EL EIE +L H IT+A+V++R D++ + YLCAYIVS Sbjct: 852 YMGRSDYQVKLRGYRIELGEIENYLFSHNSITDAIVIDRNDEKGNKYLCAYIVSTTDLDI 911 Query: 910 HELKEYLKKQLPDYLIPLHFIEVQEIPLTVNGKVDTALLEEIAPPENADKTYIQPRNEHE 969 E++ +L +LPDY++P HF+ +Q +PLT NGKVD LL E E + Y + N+ E Sbjct: 912 SEIRMFLSSKLPDYMLPSHFVILQSLPLTSNGKVDRKLLPEPKLEEESKAYYCEFENDTE 971 Query: 970 AQLIQVVGEVLRVDGAGVKHNFYHLGGDSIQAIRIASKMSQKGFKLKVKDILSFPVLEEM 1029 ++I+V+ EVL +D NFY LGGDSI+AI+IAS++ + LKVKDIL ++ E Sbjct: 972 EKIIKVICEVLGIDKISPTDNFYQLGGDSIKAIQIASRLKSEAINLKVKDILLNTIIGE- 1030 Query: 1030 AAFIEREQSEAV----EQGAAEGGIPLTPILSYFFSQHFAKAGHYHQSVMAVLKREIGLD 1085 F+ER + + + QG EG I TPI +FF Q F HY+QSV+ LK+ I L+ Sbjct: 1031 --FVERAKKQILPHKAAQGPCEGSILPTPITQWFFRQKFNNENHYNQSVLLDLKQNISLE 1088 Query: 1086 TLEKALSALIRHHDSLRINCRSDNGGLFYNQEHYHTRPSIEEYDFSDLSLPEQEARLGEA 1145 +E AL L++ HDSLRIN + GL+YN ++ I+ D S +S + + Sbjct: 1089 VIETALGVLVKQHDSLRINYDRNTDGLYYNNKYTERNFEIKVCDLSSVSQEKVRHEIKVL 1148 Query: 1146 AQRLAASFDLQHSLLLKAAVF---ELGHVRKMLLIAHHLVVDGVSWRIILEDMNTLLQQI 1202 + L + D++ +L KA + E G+ K+LL AHHLV+D VSWRI+L+D + +L+ I Sbjct: 1149 GEGLKSGMDIEKDILFKAYFYKNEEKGN--KLLLTAHHLVIDAVSWRILLDDFSAILKSI 1206 Query: 1203 HHGQEAALPLKTSSYQKWATALEASRE-TLGMKEEEYWNSVLQKHFTFSADHDRGADTLA 1261 + LP K+ S QKWA L+ E + E +YW + ++ F F D G D L Sbjct: 1207 SMSETIKLPPKSDSMQKWAETLKIFGEREVNTDELKYWENTIENDFVFPVDFQLGEDILE 1266 Query: 1262 SCHTLISGLGQPETAALLSEANIPYNTEPHDLLLTSLLVTVKEWTGSRDIVIELEGHGRE 1321 +C T+ L + ++ L EAN YNT ++LL +L + T ++IELEGHGRE Sbjct: 1267 NCDTITGNLSEEDSDKLTLEANRAYNTVTNELLFIALSQVLSNLTQRNRVLIELEGHGRE 1326 Query: 1322 DIDELVDVTRTVGWFTSLYPFGITLNGEALPGQIKQVKEERRRVPGNGIGFGLLRQLGRI 1381 +I ++VD++RTVGWFTS+YP + ++ + L QI+QVKE+ R VP GIGFG+L L + Sbjct: 1327 NISDIVDISRTVGWFTSIYPVSVRMDSDDLGTQIRQVKEQLREVPRKGIGFGILSGLSQS 1386 Query: 1382 GDHRLRKYIRFNYLGEFTEDHGGGNLTLSGDQFQHNVSGDNHLTSVLDINCFVIGGRLQL 1441 + RK+IRFN+LGE LS + V N +T ++DIN +I RL + Sbjct: 1387 INEDGRKHIRFNFLGELDTTFNNDYFELSEEDSGSEVCKKNRMTCLIDINAMIIKKRLSV 1446 Query: 1442 RLTYSRNKFLDMTMERFQTHWIRNLKLVLEHCSNTERKEYTPSDFDTVDISQEELDSLF 1500 +TYSRN F T+ER +++ ++ ++ HC N + +YTPSDF+ ++ISQ++LD LF Sbjct: 1447 AVTYSRNSFKKETIERLLDNFLEQIRKLILHCCNQLQPDYTPSDFELINISQDQLDDLF 1505 >C1FRI4.1 C1FRI4_CLOBJ Nonribosomal peptide synthetase subunit Length = 1494 Score = 1384 bits (3581), Expect = 0.0, Method: Compositional matrix adjust. Identities = 653/1491 (43%), Positives = 988/1491 (66%), Gaps = 7/1491 (0%) Query: 12 FYPLTHPQQRIWSIEQIYPQTPLHNIGGTIRIKGPVQFPVLEKAIDLFIQSHEALRLRIA 71 +Y LTHPQ+RIW I+++ +PLHNIGG + I G + +E I++ I+++E LRLR Sbjct: 8 YYNLTHPQKRIWYIDKVNLDSPLHNIGGCLNIYGNICIDKMEDTINIIIKNNEGLRLRFK 67 Query: 72 AENGEPRQYIGHNNDFPLDFIDFSTCSEPEREFADWVESIAQKPFVLENERLFYFAMFRV 131 ++G+P QYI ++F+DFS C P E+ W E++ + +EN +L+YFA++++ Sbjct: 68 EKDGQPVQYIQEFKKEKIEFLDFSKCINPREEYEKWSENLFKTNSFIENNQLYYFAIYKI 127 Query: 132 SDHENGYLAKFHHIVADGWSMNIMTDQISGIYTRLLRGERVEVQPGPSYLEYRDEEQAYL 191 S E G L HHI++DGWS+N++ QI IY++L+ E + + SY+++ EEQ YL Sbjct: 128 SRKEYGVLLNIHHIISDGWSINLIEKQICKIYSKLINNEDISLNEYYSYVDFVHEEQKYL 187 Query: 192 ASERFHKNRTFWTGKYRALPDSFLNASSDRLAGNRKTYEWSPELSARIKGLAAAHNCSLN 251 S+RF KN+ FW K++ + + FL +S L G R+ + LS +IK SLN Sbjct: 188 KSDRFIKNKNFWREKFKDISEEFLYKTSSSLEGKRQCFNIDINLSNKIKKFIDNKKYSLN 247 Query: 252 TFFITAYLLYTHKITGQDDLVVGTPVLNRSGRRQKSTFGMYTSTMPFRYVIDGSSSVLDT 311 TFFI L+Y +K T + DL++GTPV NR+G+ QKST GM+TST+PFR+ +D +V + Sbjct: 248 TFFIVILLIYINKTTYKKDLIIGTPVFNRTGKNQKSTVGMFTSTVPFRFTLDTELTVENL 307 Query: 312 MTRINSELMACYFHQRYPYDRLIQELELKKKGLDQLFNVCVNYYNTKLGTEINGYPVDSV 371 M IN EL C+ +Q+YPYD L+++LEL K G D LF +CVNYYN+ +ING + Sbjct: 308 MKLINRELKFCFLNQKYPYDLLVKDLELSKLGYDSLFKMCVNYYNSNYVNDINGNKAEVK 367 Query: 372 EFYSGQQMYSMQLVLKEWTGSGSITASFDYKLNDFTDEQIDDMYGHLTTLITQMVSDPEA 431 E+Y G Q YS+QL +KEW +IT +FD+K ++TD++I MY + +I Q++ + + Sbjct: 368 EYYCGNQSYSLQLTVKEWE-ENNITLNFDFKTLEYTDQEIKTMYKSMINIINQVIENEQL 426 Query: 432 QISQISILSKEEWTERVHSYNATQAAYPHDKTICQLFEEQAEKTPDAIAVTCKNEHLTYK 491 +++QI +L+KEE +V+ N+T YP K +C+LFEEQ KTP+ + V K + LTYK Sbjct: 427 KVNQIKLLNKEERNSKVYDLNSTTNYYPQ-KAVCELFEEQVMKTPNKVVVEFKEKTLTYK 485 Query: 492 QLNGKANQLARFLIEKGVGRETIVGLLTAHSLETVISVLGIGKAGGAFLPIDPGNPAERL 551 +LN KANQLA L EKG+ +++IV ++ HS+E +IS+LG+ K G A+LPIDP P ER+ Sbjct: 486 ELNEKANQLANHLREKGIDKKSIVSIMETHSIELIISILGVLKTGAAYLPIDPNYPVERI 545 Query: 552 DYILQDAGAKFLLTNLSLVDECSFDGVIINLEEIKYDAYRTSNVKPVSKPDDLVYVIYTS 611 +Y+L+D+ + LLTN + DE F G IIN+ Y N+ + DLVY+IYTS Sbjct: 546 NYMLEDSKSNMLLTNFKVTDEIKFKGNIININNEDLQGYSKINLPEANSLSDLVYIIYTS 605 Query: 612 GSTGRPKGTMIEHRGLVNYICWAKKVYVKQTEEVFPLYSSLAFDLTVTSLFTPLISGGAI 671 GSTG+PKG MIEH+GL NYI WA K+Y+K +E LYSS++FDLTVTS+FTPLISG I Sbjct: 606 GSTGKPKGVMIEHQGLTNYIWWANKMYLKDEDEGMALYSSISFDLTVTSIFTPLISGNKI 665 Query: 672 MVYRDDEDEYVLFRILEENQATIVKLTPSHLSLLLDRDQLNSSVKSFIVGGENLKASLAK 731 ++Y +DE E+VL++IL EN+AT+VKLTP+HL+LL D D SS+K FIVGGE+LK LAK Sbjct: 666 IIYDNDETEFVLYKILRENKATVVKLTPAHLTLLKDMDNTKSSIKRFIVGGEDLKVKLAK 725 Query: 732 KIYDRFGGNVEIFNEYGPTETVVGCMIHSYAPDTDTRAAVPIGRPADNVQIYLLDKSLAP 791 ++ + FG N++I+NEYGPTETVVGCMI+ Y D D +VPIGRPADNVQIY+LD L P Sbjct: 726 EVCNSFGKNIKIYNEYGPTETVVGCMIYKYDEDKDKGVSVPIGRPADNVQIYVLDNELNP 785 Query: 792 VPVHAVGEIYIAGDGVARGYLNNPELTAEKFIDNPFAPGKRMYKTGDQGRFLRDGTLEYI 851 V VGE+YI+GDGVARGYLN LT E+FI+N F GKRMYKTGD R+L +G++EY+ Sbjct: 786 VSTGFVGELYISGDGVARGYLNREGLTHERFIENSFIKGKRMYKTGDTARYLENGSIEYV 845 Query: 852 GRADKQIKIRGYRVELEEIEKHLLQHTGITEAVVLNRQDKQQHAYLCAYIVSERRFAAHE 911 GR D Q+KIRG+R+EL EIE++L+++ + +AVV+ ++D ++ +L AY+V+++ + Sbjct: 846 GRIDNQVKIRGHRIELGEIERYLIENECVKDAVVVYKEDSSKNKFLNAYLVAKKEITDLQ 905 Query: 912 LKEYLKKQLPDYLIPLHFIEVQEIPLTVNGKVDTALLEEIAPPENADKTYIQPRNEHEAQ 971 LKE+L K LP Y++P +F+ + ++PLT+NGKV+ ALL E PE ++ +I+ E + Sbjct: 906 LKEWLLKFLPKYMLPTNFVFMGKLPLTLNGKVNYALLPE---PETVEREFIKYATLAEKE 962 Query: 972 LIQVVGEVLRVDGAGVKHNFYHLGGDSIQAIRIASKMSQKGFKLKVKDILSFPVLEEMAA 1031 L++ + E+L ++ + N+Y LGGDSI+AI+I+SK+ G +KVKDIL++ +EE++A Sbjct: 963 LVKAMEEILSIENISMNDNYYQLGGDSIKAIQISSKLKNIGLNIKVKDILAYDSIEEISA 1022 Query: 1032 FIER-EQSEAVEQGAAEGGIPLTPILSYFFSQHFAKAGHYHQSVMAVLKREIGLDTLEKA 1090 IE E + Q +EG + TPI+ +FF+Q F+ Y+Q V+ K ++ ++ + Sbjct: 1023 AIEESEIIRLISQDKSEGTVEKTPIVEWFFNQKFSNESFYNQYVLLEYKGKLDINKVIIV 1082 Query: 1091 LSALIRHHDSLRINCRSDNGGLFYNQEHYHTRPSIEEYDFSDLSLPEQEARLGEAAQRLA 1150 ++ LI HHD+LRIN + L+YN + Y+ + + ++ S+ S +Q + + Sbjct: 1083 VNKLIEHHDALRINYNKRSNELYYNDKKYNEIHAFKYFNLSEYSYKDQCKNIKKLINETN 1142 Query: 1151 ASFDLQHSLLLKAAVFELGHVRKMLLI-AHHLVVDGVSWRIILEDMNTLLQQIHHGQEAA 1209 +S ++++S L + +L R+ LL AHHL++DGVSWR+IL+D T+L+Q+ G + Sbjct: 1143 SSINIENSSLFNVVMMDLEDNRQALLFTAHHLIIDGVSWRVILDDFITILKQLDEGSKIR 1202 Query: 1210 LPLKTSSYQKWATALEASRETLGMKEEEYWNSVLQKHFTFSADHDRGADTLASCHTLISG 1269 LPLKT SY++W+ AL+ R +E YW S+L K +++ D++ D + + + L Sbjct: 1203 LPLKTHSYKEWSEALQTYRRNDFSEEVGYWKSILDKEISYNVDYNNEEDIVETSNILSKE 1262 Query: 1270 LGQPETAALLSEANIPYNTEPHDLLLTSLLVTVKEWTGSRDIVIELEGHGREDIDELVDV 1329 + + ++L+ + + YN + ++ L+ L++T+ + T +I++ELE HGRE I++ +DV Sbjct: 1263 IDEETFSSLIQKVDEIYNMDLNEALIIGLVLTLNKLTKKDEIIVELERHGREAINDYIDV 1322 Query: 1330 TRTVGWFTSLYPFGITLNGEALPGQIKQVKEERRRVPGNGIGFGLLRQLGRIGDHRLRKY 1389 +RTVGWFTS+YP ++ E + IK +KE+ R +P NG + +L+ L + + KY Sbjct: 1323 SRTVGWFTSMYPAYFSIEHEDIEDNIKSLKEQFRNIPNNGFNYSILKFLNKKLKGQESKY 1382 Query: 1390 IRFNYLGEFTEDHGGGNLTLSGDQFQHNVSGDNHLTSVLDINCFVIGGRLQLRLTYSRNK 1449 +RFNYLG+F L +S +F N LT+++DI +I +L++ YS+ + Sbjct: 1383 VRFNYLGDFDNIIDKEKLNISDIEFGLCSDDKNSLTALIDITAIIINKKLKVTAEYSKRR 1442 Query: 1450 FLDMTMERFQTHWIRNLKLVLEHCSNTERKEYTPSDFDTVDISQEELDSLF 1500 F D +E+F +I LKL+L+ CSN KE+TPSDFD VDISQE+LD+LF Sbjct: 1443 FKDEIVEKFIESYIETLKLILDKCSNKGFKEFTPSDFDAVDISQEDLDALF 1493 >A9VQN1.1 A9VQN1_BACWK Amino acid adenylation domain Length = 1476 Score = 1369 bits (3543), Expect = 0.0, Method: Compositional matrix adjust. Identities = 657/1486 (44%), Positives = 977/1486 (65%), Gaps = 20/1486 (1%) Query: 25 IEQIYPQTPLHNIGGTIRIKGPVQFPVLEKAIDLFIQSHEALRLRIAAENGEPRQYIGHN 84 +E+I P PLHNIGGT++I+G V F LEKAI+ FI+ ++ +R R + + QY+ Sbjct: 1 MEKINPHQPLHNIGGTVKIQGEVDFDCLEKAINYFIKKNDGIRHRFVESDEKVHQYVEKY 60 Query: 85 NDFPLDFIDFSTCSEPEREFADWVESIAQKPFVLENERLFYFAMFRVSD-HENGYLAKFH 143 + + + + F++ +++ WV+ A KPF + + LF FA+F++ D E GY K H Sbjct: 61 HKYQVRYTIFNS----QKDLDAWVQQEAAKPFDINEQDLFDFALFKLQDTKEGGYFVKVH 116 Query: 144 HIVADGWSMNIMTDQISGIYTRLLRGERVEVQPGPSYLEYRDEEQAYLASERFHKNRTFW 203 HI++DGWSMN++T+QI YT++L+GE++ Q +Y+ ++E++YL S+RF K++ FW Sbjct: 117 HIISDGWSMNLLTEQICNAYTQILKGEKITDQLNSTYMYCLEKEESYLTSKRFMKDKNFW 176 Query: 204 TGKYRALPDSFLNASSDRLAGNRKTYEWSPELSARIKGLAAAHNCSLNTFFITAYLLYTH 263 K+ LP D NRKTY + S IK A N S+ FF+ Y +Y + Sbjct: 177 NEKFSKLPIVKRKNEVDCAKANRKTYSLTNNQSDEIKQFATDINVSVYAFFVALYYIYLN 236 Query: 264 KITGQDDLVVGTPVLNRSGRRQKSTFGMYTSTMPFRYVIDGSSSVLDTMTRINSELMACY 323 K+ GQDDL++G PVLNR+G+ +K+ GM TSTMPFR+ +D +VLD + IN EL+ CY Sbjct: 237 KVNGQDDLIIGMPVLNRAGKNEKNIVGMLTSTMPFRHTVDSEMTVLDFIKGINRELVRCY 296 Query: 324 FHQRYPYDRLIQELELKKKGLDQLFNVCVNYYNTKLGTEINGYPVDSVEFYSGQQMYSMQ 383 +HQ+YPYD L+++LELKKKG LF+ C+NYYNTKL TEING P+++ EFY+ Q+YS+Q Sbjct: 297 YHQKYPYDVLVKDLELKKKGYGDLFDTCINYYNTKLPTEINGTPIENEEFYNRNQIYSIQ 356 Query: 384 LVLKEWTGSGSITASFDYKLNDFTDEQIDDMYGHLTTLITQMVSDPEAQISQISILSKEE 443 L+++EW+ G DYK + +T++QI+ MY ++ L+ QM+ P ++ ++ IL ++ Sbjct: 357 LIIREWSRLGGFNLDIDYKDHMYTEKQIEQMYLGISHLLNQMLESPNKKLMELEILPEDM 416 Query: 444 WTERVHSYNATQAAYPHDKTICQLFEEQAEKTPDAIAVTCKNEHLTYKQLNGKANQLARF 503 W + ++ +NAT YP DKTI QLFEEQ E+TPD +A+ +++ LTY++LN ++NQLAR+ Sbjct: 417 WNKLIYEFNATNREYPKDKTIHQLFEEQVERTPDRVAICLEDKELTYRELNDRSNQLARY 476 Query: 504 LIEKGVGRETIVGLLTAHSLETVISVLGIGKAGGAFLPIDPGNPAERLDYILQDAGAKFL 563 +++K V + T++G+ T HSLET+I +LGI KAG +LPIDP P+ER++Y+LQD+ L Sbjct: 477 ILKKNVTKGTVIGISTTHSLETIIGILGILKAGAVYLPIDPQYPSERVNYMLQDSDINIL 536 Query: 564 LTNLSLVDECSFDGVIINLEEIKYDAYR-----TSNVKPVSKPDDLVYVIYTSGSTGRPK 618 TN + + +D + +E I A TSN+K S+P DL Y+IYTSGSTG PK Sbjct: 537 FTNFDISHQ--WDLSLYAVEVIHISAAHIYMGDTSNIKNRSEPTDLAYIIYTSGSTGNPK 594 Query: 619 GTMIEHRGLVNYICWAKKVYVKQTE-EVFPLYSSLAFDLTVTSLFTPLISGGAIMVYRDD 677 GTMIE +GLVNYI WA +VYV +E EVFPLYSSLAFDLTVT++FTPLISG I++Y D Sbjct: 595 GTMIEQKGLVNYISWANQVYVGASENEVFPLYSSLAFDLTVTTIFTPLISGNQIIIYPAD 654 Query: 678 EDEYVLFRILEENQATIVKLTPSHLSLLLDRDQLNSSVKSFIVGGENLKASLAKKIYDRF 737 +EYVL+RI +E +A+I+KLTPSHL LL D D + S+K IVGGENL LA I + Sbjct: 655 ANEYVLYRIFKEKKASIIKLTPSHLFLLKDSDFVGCSIKKIIVGGENLTVDLAANIQKKL 714 Query: 738 GGNVEIFNEYGPTETVVGCMIHSYAPDTDTRAAVPIGRPADNVQIYLLDKSLAPVPVHAV 797 G +I+NEYGPTETVVGCMIH + + D +VPIG PA N++IY+LD L PVP+ V Sbjct: 715 GRETKIYNEYGPTETVVGCMIHQFDIEKDKGVSVPIGVPAQNMKIYVLDSDLRPVPMGVV 774 Query: 798 GEIYIAGDGVARGYLNNPELTAEKFIDNPFAPGKRMYKTGDQGRFLRDGTLEYIGRADKQ 857 GEIYI+G+GVARGY NN +LT E+FI NP++ ++MYK+GD RF+ +EY+GR D Q Sbjct: 775 GEIYISGEGVARGYFNNQDLTRERFIVNPYSEKEQMYKSGDLARFIEGDKIEYLGRKDDQ 834 Query: 858 IKIRGYRVELEEIEKHLLQHTGITEAVVLNRQDKQQHAYLCAYIVSERRFAAHELKEYLK 917 +K+RG+R+EL+EIE +L ++ I E VV++++D + YLCAY + EL +LK Sbjct: 835 VKVRGFRIELKEIEINLQKYPSIKEVVVIDQEDYDGNHYLCAYYTENAKVKTSELFRFLK 894 Query: 918 KQLPDYLIPLHFIEVQEIPLTVNGKVDTALLEEIAPPENADKTYIQPRNEHEAQLIQVVG 977 + LP Y+IP +FI ++EIPLT NGK+D L P+ K + E E+ L+ ++ Sbjct: 895 EILPVYMIPSYFIVLKEIPLTFNGKLDREAL-----PKPEVKIEKKTEGEIESDLLGIIR 949 Query: 978 EVLRVDGAGVKHNFYHLGGDSIQAIRIASKMSQKGFKLKVKDILSFPVLEEMAAFIEREQ 1037 EVL V+ ++ NFYHLGGDSI+AI+I+SK+ +KG K+K KDIL+ PV+E+M ++E Sbjct: 950 EVLNVEKVSIRDNFYHLGGDSIKAIQISSKIREKGIKIKTKDILANPVIEDMILYLEMNS 1009 Query: 1038 S-EAVEQGAAEGGIPLTPILSYFFSQHFAKAGHYHQSVMAVLKREIGLDTLEKALSALIR 1096 + E G I P +S+FFSQ HY QSV+ +K ++ + LE A S L+ Sbjct: 1010 TKEQKSNQQCVGSIETIPSISWFFSQDLNNINHYTQSVLVKVKDDVEVGILESAFSLLVC 1069 Query: 1097 HHDSLRINCRSDNGGLFYNQEHYHTRPSIEEYDFSDLSLPEQEARLGEAAQRLAASFDLQ 1156 HHD+ R+N R + LFYNQ +Y+ + IE D S+LS EQ R+ + L +SF+++ Sbjct: 1070 HHDAFRLNYRMETKELFYNQNNYNKKIKIESLDLSELSKIEQSIRIASIGEILKSSFNIE 1129 Query: 1157 HSLLLKAAVFELGHV-RKMLLIAHHLVVDGVSWRIILEDMNTLLQQIHHGQEAALPLKTS 1215 + +LLK +F+LG +++L+ AHHL VDG+SWRII ED+N L +QI + Q+ +LP K + Sbjct: 1130 NEILLKVCIFDLGDFGKRLLMTAHHLAVDGISWRIIFEDINQLYKQIENKQKTSLPPKDN 1189 Query: 1216 SYQKWATALEASRETLGMKEEEYWNSVLQKHFTFSADHDRGADTLASCHTLISGLGQPET 1275 S Q WA L+ + + E+ YW V Q D D G D + C +I L + ET Sbjct: 1190 SVQDWAIELKRMSKKIPESEKRYWEHVYQYEENSFNDFDLGLDRMEFCEKMIKKLTEEET 1249 Query: 1276 AALLSEANIPYNTEPHDLLLTSLLVTVKEWTGSRDIVIELEGHGREDIDELVDVTRTVGW 1335 LL +AN Y T+ ++L++ +L + + ++ + D++IE+EGHGRE++++ +DV+RT+GW Sbjct: 1250 MQLLQKANEAYRTKGNELMIIALSLVMAKYIKTNDVIIEIEGHGREELNDEIDVSRTIGW 1309 Query: 1336 FTSLYPFGITLNGEALPGQIKQVKEERRRVPGNGIGFGLLRQLGRIGDHRLRKYIRFNYL 1395 FTSL+P + + QIKQ+KE+ R VP G+ +G+L+ + + RKY+RFNYL Sbjct: 1310 FTSLFPIRLQFEDVDISQQIKQLKEQLRSVPSKGLNYGVLKYISKELSSESRKYVRFNYL 1369 Query: 1396 GEFTEDHGGGNLTLSGDQFQHNVSGDNHLTSVLDINCFVIGGRLQLRLTYSRNKFLDMTM 1455 G+F G + + + S N + +LDI + + +L L +TYS+NKF T+ Sbjct: 1370 GDFNATFSNGIFEFAYENSGQDNSNKNEMDCLLDIVAYTVDKKLNLSITYSKNKFKQETI 1429 Query: 1456 ERFQTHWIRNLKLVLEHCSNTERKEYTPSDFDTVDISQEELDSLFS 1501 +F ++ L+ +++HC + E+TPSDF+T ++S E+L+++F+ Sbjct: 1430 SQFFMEYMNQLRDLIQHCCQKKHAEFTPSDFETANLSSEDLENIFN 1475 >C2SIR0.1 C2SIR0_BACCE Putative uncharacterized protein Length = 1476 Score = 1367 bits (3537), Expect = 0.0, Method: Compositional matrix adjust. Identities = 656/1486 (44%), Positives = 977/1486 (65%), Gaps = 20/1486 (1%) Query: 25 IEQIYPQTPLHNIGGTIRIKGPVQFPVLEKAIDLFIQSHEALRLRIAAENGEPRQYIGHN 84 +E+I P PLHNIGGT++I+G V F LEKAI+ FI+ ++ +R R + + QY+ Sbjct: 1 MEKINPHQPLHNIGGTVKIQGEVDFDCLEKAINYFIKKNDGIRHRFVESDEKVHQYVEKY 60 Query: 85 NDFPLDFIDFSTCSEPEREFADWVESIAQKPFVLENERLFYFAMFRVSD-HENGYLAKFH 143 + + + + F++ +++ WV+ A KPF + + LF FA+F++ D E GY K H Sbjct: 61 HKYQVRYTIFNS----QKDLDAWVQQEAAKPFDINEQDLFDFALFKLQDTKEGGYFVKVH 116 Query: 144 HIVADGWSMNIMTDQISGIYTRLLRGERVEVQPGPSYLEYRDEEQAYLASERFHKNRTFW 203 HI++DGWSMN++T+QI YT++L+GE++ Q +Y+ ++E++YL S+RF K++ FW Sbjct: 117 HIISDGWSMNLLTEQICNAYTQILKGEKITDQLNSTYMYCLEKEESYLTSKRFMKDKNFW 176 Query: 204 TGKYRALPDSFLNASSDRLAGNRKTYEWSPELSARIKGLAAAHNCSLNTFFITAYLLYTH 263 K+ LP D NRKTY + S IK A N S+ FF+ Y +Y + Sbjct: 177 NEKFSKLPIVKRKNEVDCAKANRKTYSLTNNQSDEIKQFATDINVSVYAFFVALYYIYLN 236 Query: 264 KITGQDDLVVGTPVLNRSGRRQKSTFGMYTSTMPFRYVIDGSSSVLDTMTRINSELMACY 323 K+ GQDDL++G PVLNR+G+ +K+ GM TSTMPFR+ +D +VLD + IN EL+ CY Sbjct: 237 KVNGQDDLIIGMPVLNRAGKNEKNIVGMLTSTMPFRHTVDSEMTVLDFIKGINRELVRCY 296 Query: 324 FHQRYPYDRLIQELELKKKGLDQLFNVCVNYYNTKLGTEINGYPVDSVEFYSGQQMYSMQ 383 +HQ+YPYD L+++LELKKKG LF+ C+NYYNTKL TEING P+++ EFY+ Q+YS+Q Sbjct: 297 YHQKYPYDVLVKDLELKKKGYGDLFDTCINYYNTKLPTEINGTPIENEEFYNRNQIYSIQ 356 Query: 384 LVLKEWTGSGSITASFDYKLNDFTDEQIDDMYGHLTTLITQMVSDPEAQISQISILSKEE 443 L+++EW+ G DYK + +T++QI+ MY ++ L+ QM+ P ++ ++ IL ++ Sbjct: 357 LIIREWSRLGGFNLDIDYKDHMYTEKQIEQMYLGISHLLNQMLESPNKKLMELEILPEDM 416 Query: 444 WTERVHSYNATQAAYPHDKTICQLFEEQAEKTPDAIAVTCKNEHLTYKQLNGKANQLARF 503 W + ++ +NAT YP DKTI QLFEEQ E+TPD +A+ +++ LTY++LN ++NQLAR+ Sbjct: 417 WNKLIYEFNATNREYPKDKTIHQLFEEQVERTPDRVAICLEDKELTYRELNDRSNQLARY 476 Query: 504 LIEKGVGRETIVGLLTAHSLETVISVLGIGKAGGAFLPIDPGNPAERLDYILQDAGAKFL 563 +++K V + T++G+ T HSLET+I +LGI KAG +LPIDP P+ER++Y+LQD+ L Sbjct: 477 ILKKNVTKGTVIGISTTHSLETIIGILGILKAGAVYLPIDPQYPSERVNYMLQDSDINIL 536 Query: 564 LTNLSLVDECSFDGVIINLEEIKYDAYR-----TSNVKPVSKPDDLVYVIYTSGSTGRPK 618 TN + + +D + +E I A TSN+K S+P DL Y+IYTSGSTG PK Sbjct: 537 FTNFDISHQ--WDLSLYAVEVIHISAAHIYMGDTSNIKNRSEPTDLAYIIYTSGSTGNPK 594 Query: 619 GTMIEHRGLVNYICWAKKVYVKQTE-EVFPLYSSLAFDLTVTSLFTPLISGGAIMVYRDD 677 GTMIE +GLVNYI WA +VYV +E EVFPLYSSLAFDLTVT++FTPLISG I++Y D Sbjct: 595 GTMIEQKGLVNYISWANQVYVGASENEVFPLYSSLAFDLTVTTIFTPLISGNQIIIYPAD 654 Query: 678 EDEYVLFRILEENQATIVKLTPSHLSLLLDRDQLNSSVKSFIVGGENLKASLAKKIYDRF 737 +EYVL+RI +E +A+I+KLTPSHL LL D D + S+K IVGGENL LA I + Sbjct: 655 ANEYVLYRIFKEKKASIIKLTPSHLFLLKDSDFVGCSIKKIIVGGENLTVDLAANIQKKL 714 Query: 738 GGNVEIFNEYGPTETVVGCMIHSYAPDTDTRAAVPIGRPADNVQIYLLDKSLAPVPVHAV 797 G +I+NEYGPTETVVGCMIH + + D +VPIG PA N++IY+LD L PVP+ V Sbjct: 715 GRETKIYNEYGPTETVVGCMIHQFDIEKDKGVSVPIGVPAQNMKIYVLDSDLRPVPMGVV 774 Query: 798 GEIYIAGDGVARGYLNNPELTAEKFIDNPFAPGKRMYKTGDQGRFLRDGTLEYIGRADKQ 857 GEIYI+G+GVARGY NN +LT E+FI NP++ ++MYK+GD RF+ +EY+GR D Q Sbjct: 775 GEIYISGEGVARGYFNNQDLTRERFIVNPYSEKEQMYKSGDLARFIEGDKIEYLGRKDDQ 834 Query: 858 IKIRGYRVELEEIEKHLLQHTGITEAVVLNRQDKQQHAYLCAYIVSERRFAAHELKEYLK 917 +K+RG+R+EL+EIE +L ++ I E VV++++D + YLCAY + EL +LK Sbjct: 835 VKVRGFRIELKEIEINLQKYPSIKEVVVIDQEDYDGNHYLCAYYTENAKVKTSELFRFLK 894 Query: 918 KQLPDYLIPLHFIEVQEIPLTVNGKVDTALLEEIAPPENADKTYIQPRNEHEAQLIQVVG 977 + LP Y+IP +FI ++EIPLT NGK+D L P+ K + E E+ L+ ++ Sbjct: 895 EILPVYMIPSYFIVLKEIPLTFNGKLDREAL-----PKPEVKIEKKTEGEIESDLVGIIR 949 Query: 978 EVLRVDGAGVKHNFYHLGGDSIQAIRIASKMSQKGFKLKVKDILSFPVLEEMAAFIEREQ 1037 EVL V+ ++ NFYHLGGDSI+AI+I+SK+ +KG K+K KDIL+ PV+E+M ++E Sbjct: 950 EVLNVEKVSIRDNFYHLGGDSIKAIQISSKIREKGIKIKTKDILANPVIEDMILYLEMTS 1009 Query: 1038 S-EAVEQGAAEGGIPLTPILSYFFSQHFAKAGHYHQSVMAVLKREIGLDTLEKALSALIR 1096 + E G I P +S+FFSQ HY QSV+ +K ++ + LE A S L+ Sbjct: 1010 TKEQKSNQQCVGSIETIPSISWFFSQDLNNINHYTQSVLVKVKDDVEVGILESAFSLLVC 1069 Query: 1097 HHDSLRINCRSDNGGLFYNQEHYHTRPSIEEYDFSDLSLPEQEARLGEAAQRLAASFDLQ 1156 HHD+ R+N R + LFYNQ +Y+ + IE D S+LS EQ R+ + L +SF+++ Sbjct: 1070 HHDAFRLNYRMETKELFYNQNNYNKKIKIESLDLSELSKTEQGIRIASIGEILKSSFNIE 1129 Query: 1157 HSLLLKAAVFELGHV-RKMLLIAHHLVVDGVSWRIILEDMNTLLQQIHHGQEAALPLKTS 1215 + +L+K +F+LG +++L+ AHHL VDG+SWRII ED+N L +QI + Q+ +LP K + Sbjct: 1130 NEILVKVCIFDLGDFGKRLLMTAHHLAVDGISWRIIFEDINQLYKQIENKQKTSLPPKDN 1189 Query: 1216 SYQKWATALEASRETLGMKEEEYWNSVLQKHFTFSADHDRGADTLASCHTLISGLGQPET 1275 S Q WA L+ + + E+ YW V Q D D G D + C +I L + ET Sbjct: 1190 SVQDWAIELKRMSKKIPESEKRYWEHVYQYEENSFNDFDLGLDRMEFCEKMIKKLTEEET 1249 Query: 1276 AALLSEANIPYNTEPHDLLLTSLLVTVKEWTGSRDIVIELEGHGREDIDELVDVTRTVGW 1335 LL +AN Y T+ ++L++ +L + + ++ + D++IE+EGHGRE++++ +DV+RT+GW Sbjct: 1250 MQLLQKANEAYRTKGNELMIIALSLVMAKYIKTNDVIIEIEGHGREELNDEIDVSRTIGW 1309 Query: 1336 FTSLYPFGITLNGEALPGQIKQVKEERRRVPGNGIGFGLLRQLGRIGDHRLRKYIRFNYL 1395 FTSL+P + + QIKQ+KE+ R VP G+ +G+L+ + + RKY+RFNYL Sbjct: 1310 FTSLFPIRLQFEDVDISQQIKQLKEQLRSVPSKGLNYGVLKYISKELSSESRKYVRFNYL 1369 Query: 1396 GEFTEDHGGGNLTLSGDQFQHNVSGDNHLTSVLDINCFVIGGRLQLRLTYSRNKFLDMTM 1455 G+F G + + + S N + +LDI + + +L L +TYS+NKF T+ Sbjct: 1370 GDFNATFSNGIFEFAYENSGQDNSNKNEMDCLLDIVAYTVDKKLNLSITYSKNKFKQETI 1429 Query: 1456 ERFQTHWIRNLKLVLEHCSNTERKEYTPSDFDTVDISQEELDSLFS 1501 +F ++ L+ +++HC + E+TPSDF+T ++S E+L+++F+ Sbjct: 1430 SQFFMEYMNQLRDLIQHCCQRKHAEFTPSDFETANLSSEDLENIFN 1475 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.137 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 9,182,790,712 Number of extensions: 404615509 Number of successful extensions: 1134418 Number of sequences better than 1.0e-05: 15981 Number of HSP's gapped: 1055408 Number of HSP's successfully gapped: 20696 Length of query: 1501 Length of database: 3,060,696,203 Length adjustment: 149 Effective length of query: 1352 Effective length of database: 1,656,964,968 Effective search space: 2240216636736 Effective search space used: 2240216636736 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 138 (57.8 bits)