BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0183.0013.p (392 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A6NT80.1 A6NT80_9BACE Putative uncharacterized protein 255 4e-66 A6TU63.1 A6TU63_ALKMQ 5'-Nucleotidase domain protein 239 4e-61 C2H6S0.1 C2H6S0_ENTFA 5'-nucleotidase family protein EC=3.1.3.6 221 9e-56 C4VIL3.1 C4VIL3_ENTFA 5'-nucleotidase family protein 219 3e-55 Q839U0.1 Q839U0_ENTFA 5'-nucleotidase family protein 217 2e-54 >A6NT80.1 A6NT80_9BACE Putative uncharacterized protein Length = 709 Score = 255 bits (652), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 148/338 (43%), Positives = 201/338 (59%), Gaps = 27/338 (7%) Query: 3 IQAGTSKLLNIVMIATSDLHGNLWGYRYEDGHETTNDGMARVAAYVREVRDSGAEVILID 62 + AGT + +I +I TSD HGN+WGY YED E+T DG+ARV+ YV +VR IL+D Sbjct: 31 LAAGTGET-HITIIGTSDTHGNIWGYSYEDMKESTGDGLARVSTYVNQVRAENPNTILVD 89 Query: 63 NGDVFQGNMLTDDIYNKRPDSIHPVSAALNAMGYAAMTLGNHEFNFGLGLIEKFRQELEF 122 GD QG ++TDD+Y+K + HPV AALN M Y A TLGNHEFNFG+ ++ + + Sbjct: 90 AGDTIQGTIMTDDLYSKDTAN-HPVPAALNYMKYDAWTLGNHEFNFGVDKLQSIIDQADM 148 Query: 123 PVLAANAAYHSGERFAEP-YTLMEIQGVRIAVIGLTNPNIPRWDAGK--VDALHFGPMAE 179 PVLAAN G F YT++E GV +A+IG+ PNIPRWD K VD L F PMA+ Sbjct: 149 PVLAANIKNADGSYFTGAGYTIVERGGVNVAIIGVDTPNIPRWDGTKQGVDKLTFEPMAD 208 Query: 180 TAQQITASLRAEGKADIIVISAHAGMVAEFDEEGGSDSAERITKLVPEADVLLVGHMHIT 239 + + KAD+I++SAHAG+ AE+ + GSD+A+ I + PE DVL +GH H T Sbjct: 209 AVAECIKEIG--DKADVIMVSAHAGLEAEYSTD-GSDAAKTILEKCPEVDVLQMGHTHTT 265 Query: 240 VKERIGDTV-IGGPRDRGREVVRFDLTVQLDGARPRVVNKEVSIVDMADWEPDPEFRRL- 297 DT+ +G ++ EVVR+DLT+ D + + V V M D EPD R + Sbjct: 266 YINN--DTIPVGEAKNNAGEVVRYDLTLNAD---KEITSATVETVSMKDVEPDQNLRNVP 320 Query: 298 -VAEAHEETMTFXXXXXXXXXXXXXXXILGYAAADFQP 334 + A E+T++F +LG+AAADFQP Sbjct: 321 AIKTAQEKTVSF-----------IQDNVLGHAAADFQP 347 >A6TU63.1 A6TU63_ALKMQ 5'-Nucleotidase domain protein Length = 729 Score = 239 bits (610), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 119/300 (39%), Positives = 179/300 (59%), Gaps = 4/300 (1%) Query: 11 LNIVMIATSDLHGNLWGYRYEDGHETTNDGMARVAAYVREVRDSGAEVILIDNGDVFQGN 70 + I ++ATSD+HG L+ + YED E GM ++A ++EVR IL+DNGD QG+ Sbjct: 34 VTITVLATSDIHGALYNWNYEDSREDNRGGMVKLATIIKEVRKENPNTILVDNGDTIQGS 93 Query: 71 MLTDDIYNK-RPDSIHPVSAALNAMGYAAMTLGNHEFNFGLGLIEKFRQELEFPVLAANA 129 +LTDD+YN D HP+ A+N MGY +MTLGNHEFNFGL LI+K +E +FP+L+AN Sbjct: 94 LLTDDLYNTILIDEPHPIIEAMNLMGYDSMTLGNHEFNFGLDLIQKIEKEADFPMLSANI 153 Query: 130 -AYHSGERFAEPYTLMEIQGVRIAVIGLTNPNIPRWDAGKVDALHFGPMAETAQQITASL 188 G F PYT+ E+ G+++ +IGLT PNIPRWD +V +L F M + A+++ L Sbjct: 154 FNKEDGSYFVTPYTIKEVAGIKVGIIGLTTPNIPRWDGPRVTSLDFRAMHKEAEKVYQKL 213 Query: 189 RAEGKADIIVISAHAGMVAEFDEEGGSDSAERITKLVPEADVLLVGHMHITVKERIGDTV 248 + DI++ +AH+G+ D EG A+ + + +P+ +VGH H T ++ Sbjct: 214 MEDEGVDIVIATAHSGLEGRHDNEGS--MAKLVAERIPQLAAFIVGHDHDTKDLKVNGVP 271 Query: 249 IGGPRDRGREVVRFDLTVQLDGARPRVVNKEVSIVDMADWEPDPEFRRLVAEAHEETMTF 308 + GP + RE+ R D+T++ G + VV +E I+ +E D E + A E T+ F Sbjct: 272 VVGPTNAAREIARVDITLEKQGDQWIVVAQETEIISAEAYEVDAELAEALRPAQETTLEF 331 >C2H6S0.1 C2H6S0_ENTFA 5'-nucleotidase family protein EC=3.1.3.6 Length = 1340 Score = 221 bits (563), Expect = 9e-56, Method: Compositional matrix adjust. Identities = 134/348 (38%), Positives = 191/348 (54%), Gaps = 39/348 (11%) Query: 7 TSKLLNIVMIATSDLHGNLWGYRYEDGHETTNDGMARVAAYVREVR-DSGAEVILIDNGD 65 TS I ++ TSD+HG LW + YED E G+++V+ V +VR + A +LIDNGD Sbjct: 103 TSTPQKITILGTSDVHGQLWNWSYEDDKELPV-GLSQVSTVVNQVRAQNPAGTVLIDNGD 161 Query: 66 VFQGNMLTDDIYNKRP---DSIHPVSAALNAMGYAAMTLGNHEFNFGLGLIEKFRQELEF 122 QG +LTDD+YNK P + HP+ A+N M Y AM LGNHEFNFGL LI+K +QE F Sbjct: 162 NIQGTILTDDLYNKAPLVNEKTHPMITAMNVMKYDAMVLGNHEFNFGLPLIKKIQQEATF 221 Query: 123 PVLAANAAYHSGERFAEPYTLMEIQ-------GVRIAVIGLTNPNIPRWDAGKVDALHFG 175 P+L+AN G RF E T E+ +++ +IGLT P+IP WD +V +L+F Sbjct: 222 PILSANTYNKDGGRFVEGTTTKELDLNQDGQPDLKVGIIGLTIPHIPLWDGPRVTSLNFL 281 Query: 176 PMAETAQQITASLRAEGKADIIVISAHAGMVAEFDEEGGSD---SAERITKLVPEADVLL 232 P+ E A++ A L+ +ADIIV S HAG + SD SA+++ + V D + Sbjct: 282 PLKEEAEKAVAELKTNDQADIIVASIHAG-------QQNSDPVASADQVIENVAGIDAYI 334 Query: 233 VGHMHITVKER----IGDTV-IGGPRDRGREVVRFDLTVQLDGARPRVVNKEVSIVDMAD 287 +GH H++ ++ G TV +GGP+D G EVV+ DL+V + + V +IV + Sbjct: 335 LGHDHLSFTKQGAAPNGKTVPVGGPKDTGTEVVKIDLSVAKNADKWEVQEGTATIVPTTN 394 Query: 288 WEPDPEFRRLVAEAHEETMTFXXXXXXXXXXXXXXXILGYAAADFQPQ 335 D + E HE+T F +G A ADF P+ Sbjct: 395 VPADEAVKAATKEYHEQTRAFIQEE------------IGTATADFLPK 430 Score = 101 bits (252), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 81/300 (27%), Positives = 147/300 (49%), Gaps = 37/300 (12%) Query: 14 VMIATSDLHGNLWGYRYEDGHETTNDGMARVAAYVREVRDSGAEVILIDNGDVFQGNMLT 73 ++ T+D+HG L + E G MAR+ + +D +++D GDVFQG ++ Sbjct: 684 TIMHTNDVHGRLEAGKGELG-------MARLKTF----KDQENPTLMVDAGDVFQGLPIS 732 Query: 74 DDIYNKRPDSIHPVSAALNAMGYAAMTLGNHEFNFGLGLIEKFRQELEFPVLAANAAYHS 133 + ++K D ++ A+N +GY AM +GNHEF+FGL + ++ +L FP+L++N Y Sbjct: 733 N--FSKGAD----MAKAMNEVGYDAMAVGNHEFDFGLEIALGYKDQLNFPILSSNTYYKD 786 Query: 134 GE-RFAEPYTLMEIQGVRIAVIGLTNPNI-PRWDAGKVDALHFGPMAETAQQITASLRAE 191 G R +PYT++E G + A++G+T P + V+ + F + + ++ E Sbjct: 787 GSGRVFDPYTIVEKAGKKFAIVGVTTPETATKTHPKNVEKVTFKDPIPEVEAVINEIK-E 845 Query: 192 GKADI--IVISAHAGMVAEFDEEG-----GSDSAERITKLVPEADVLLV-GHMHITVK-- 241 ADI V++ H G+ DE G AE +++ PE D+ ++ GH H V+ Sbjct: 846 KYADIQAFVVTGHLGV----DETTPHIWRGDTLAETLSQTYPELDITVIDGHSHTAVESG 901 Query: 242 ERIGDTVIGGPRDRGREVVRFDLTVQLDGARPRVVNKEVSIVDMADWEPDPEFRRLVAEA 301 +R G + G + + + + K +S ++ + +P + +V EA Sbjct: 902 KRYGKVIYA---QTGNYLNNVGIVTAPESEPTKKTAKLISAAELLELPENPAVKAIVDEA 958 >C4VIL3.1 C4VIL3_ENTFA 5'-nucleotidase family protein Length = 1004 Score = 219 bits (559), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 132/348 (37%), Positives = 190/348 (54%), Gaps = 39/348 (11%) Query: 7 TSKLLNIVMIATSDLHGNLWGYRYEDGHETTNDGMARVAAYVREVR-DSGAEVILIDNGD 65 TS I ++ TSD+HG LW + YED E G+++V+ V +VR + A +LIDNGD Sbjct: 103 TSTPQKITILGTSDVHGQLWNWSYEDDKELPV-GLSQVSTVVNQVRAQNPAGTVLIDNGD 161 Query: 66 VFQGNMLTDDIYNKRP---DSIHPVSAALNAMGYAAMTLGNHEFNFGLGLIEKFRQELEF 122 QG +LTDD+YNK P + HP+ A+N M Y AM LGNHEFNFGL LI+K ++E F Sbjct: 162 NIQGTILTDDLYNKAPLVNEKTHPMITAMNVMKYDAMVLGNHEFNFGLPLIQKIQKEATF 221 Query: 123 PVLAANAAYHSGERFAEPYTLMEIQ-------GVRIAVIGLTNPNIPRWDAGKVDALHFG 175 P+L+AN G RF E T E+ +++ +IGLT P+IP WD +V +L+F Sbjct: 222 PILSANTYNKDGSRFVEGTTTKELDLNQDGQPDLKVGIIGLTIPHIPLWDGPRVTSLNFL 281 Query: 176 PMAETAQQITASLRAEGKADIIVISAHAGMVAEFDEEGGSD---SAERITKLVPEADVLL 232 P+ E A++ L+ +ADIIV S HAG + SD SA+++ + V D + Sbjct: 282 PLKEEAEKAVTELKTNDQADIIVASIHAG-------QQNSDLAASADQVIENVAGIDAYI 334 Query: 233 VGHMHITVKER----IGDTV-IGGPRDRGREVVRFDLTVQLDGARPRVVNKEVSIVDMAD 287 +GH H++ ++ G TV +GGP+D G EVV+ DL+V + + V +IV + Sbjct: 335 LGHDHLSFTKQGAAPNGKTVPVGGPKDTGTEVVKIDLSVAKNADKWEVQEGTATIVPTTN 394 Query: 288 WEPDPEFRRLVAEAHEETMTFXXXXXXXXXXXXXXXILGYAAADFQPQ 335 D + E HE+T F +G A ADF P+ Sbjct: 395 VPADEAVKAATKEYHEKTRAFIQEE------------IGTATADFLPK 430 Score = 100 bits (248), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 81/300 (27%), Positives = 147/300 (49%), Gaps = 37/300 (12%) Query: 14 VMIATSDLHGNLWGYRYEDGHETTNDGMARVAAYVREVRDSGAEVILIDNGDVFQGNMLT 73 ++ T+D+HG L + E G MAR+ + +D +++D GDVFQG ++ Sbjct: 684 TIMHTNDVHGRLEAGKGELG-------MARLKTF----KDQENPTLMVDAGDVFQGLPIS 732 Query: 74 DDIYNKRPDSIHPVSAALNAMGYAAMTLGNHEFNFGLGLIEKFRQELEFPVLAANAAYHS 133 + ++K D ++ A+N +GY AM +GNHEF+FGL + ++ +L FP+L++N Y Sbjct: 733 N--FSKGAD----MAKAMNEVGYDAMAVGNHEFDFGLEIALGYKDQLNFPILSSNTYYKD 786 Query: 134 GE-RFAEPYTLMEIQGVRIAVIGLTNPNI-PRWDAGKVDALHFGPMAETAQQITASLRAE 191 G R +PYT++E G + A++G+T P + V+ + F + + ++ E Sbjct: 787 GSGRVFDPYTIVEKAGKKFAIVGVTTPETATKTHPKNVEKVTFKDPIPEVEAVINEIK-E 845 Query: 192 GKADI--IVISAHAGMVAEFDEEG-----GSDSAERITKLVPEADVLLV-GHMHITVK-- 241 ADI V++ H G+ DE G AE +++ PE D+ ++ GH H V+ Sbjct: 846 KYADIQAFVVTGHLGV----DETTPHIWRGDTLAETLSQTYPELDINVIDGHSHTAVESG 901 Query: 242 ERIGDTVIGGPRDRGREVVRFDLTVQLDGARPRVVNKEVSIVDMADWEPDPEFRRLVAEA 301 +R G + G + + + + K +S ++ + +P + +V EA Sbjct: 902 KRYGKVIYA---QTGNYLNNVGIVTAPESEPTKKTAKLISAAELLELPENPAVKAIVDEA 958 >Q839U0.1 Q839U0_ENTFA 5'-nucleotidase family protein Length = 1313 Score = 217 bits (552), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 132/346 (38%), Positives = 189/346 (54%), Gaps = 34/346 (9%) Query: 7 TSKLLNIVMIATSDLHGNLWGYRYEDGHETTNDGMARVAAYVREVR-DSGAEVILIDNGD 65 TS I ++ TSD+HG LW + YED E G+++V+ V +VR + A +LIDNGD Sbjct: 103 TSTPQKITILGTSDVHGQLWNWSYEDDKELPV-GLSQVSTVVNQVRAQNPAGTVLIDNGD 161 Query: 66 VFQGNMLTDDIYNKRP---DSIHPVSAALNAMGYAAMTLGNHEFNFGLGLIEKFRQELEF 122 QG +LTDD+YNK P + HP+ A+N M Y AM LGNHEFNFGL LI+K +QE F Sbjct: 162 NIQGTILTDDLYNKAPLVNEKTHPMITAMNVMKYDAMVLGNHEFNFGLPLIKKIQQEATF 221 Query: 123 PVLAANA-AYHSGERFAEPYTLMEIQ-------GVRIAVIGLTNPNIPRWDAGKVDALHF 174 P+L+AN G RF E T E+ +++ +IGLT P+IP WD +V +L+F Sbjct: 222 PILSANTYNKEDGLRFVEGTTTKELDFNQDGQPDLKVGIIGLTIPHIPLWDGPRVTSLNF 281 Query: 175 GPMAETAQQITASLRAEGKADIIVISAHAGMVAEFDEEGGSDSAERITKLVPEADVLLVG 234 P+ E A++ L+A +ADIIV S HAG + SA+++ + V D ++G Sbjct: 282 LPLKEEAEKAVTELKANDQADIIVASIHAGQ----QNSDPAASADQVIENVAGIDAYILG 337 Query: 235 HMHITVKER----IGDTV-IGGPRDRGREVVRFDLTVQLDGARPRVVNKEVSIVDMADWE 289 H H++ ++ G TV +GGP+D G EVV+ DL+V + + V +IV + Sbjct: 338 HDHLSFTKQGAAPNGKTVPVGGPKDTGTEVVKIDLSVAKNADKWEVQEGTATIVPTTNVP 397 Query: 290 PDPEFRRLVAEAHEETMTFXXXXXXXXXXXXXXXILGYAAADFQPQ 335 D + E HE+T F +G A ADF P+ Sbjct: 398 ADEAVKAATKEYHEKTRAFIQEE------------IGTATADFLPK 431 Score = 103 bits (257), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 81/300 (27%), Positives = 147/300 (49%), Gaps = 37/300 (12%) Query: 14 VMIATSDLHGNLWGYRYEDGHETTNDGMARVAAYVREVRDSGAEVILIDNGDVFQGNMLT 73 ++ T+D+HG L + E G MAR+ + +D +++D GDVFQG ++ Sbjct: 685 TIMHTNDVHGRLEAGKGELG-------MARLKTF----KDQENPTLMVDAGDVFQGLPIS 733 Query: 74 DDIYNKRPDSIHPVSAALNAMGYAAMTLGNHEFNFGLGLIEKFRQELEFPVLAANAAYHS 133 + ++K D ++ A+N +GY AM +GNHEF+FGL + ++ +L FP+L++N Y Sbjct: 734 N--FSKGAD----MAKAMNEVGYDAMAVGNHEFDFGLEIALGYKDQLNFPILSSNTYYKD 787 Query: 134 GE-RFAEPYTLMEIQGVRIAVIGLTNPNI-PRWDAGKVDALHFGPMAETAQQITASLRAE 191 G R +PYT++E G + A++G+T P + V+ + F + + ++ E Sbjct: 788 GSGRVFDPYTIVEKSGKKFAIVGVTTPETATKTHPKNVEKVTFKDPIPEVEAVIKEIK-E 846 Query: 192 GKADI--IVISAHAGMVAEFDEEG-----GSDSAERITKLVPEADVLLV-GHMHITVK-- 241 ADI V++ H G+ DE G AE +++ PE D+ ++ GH H V+ Sbjct: 847 KYADIQAFVVTGHLGV----DETTPHIWRGDTLAETLSQTYPELDITVIDGHSHTAVESG 902 Query: 242 ERIGDTVIGGPRDRGREVVRFDLTVQLDGARPRVVNKEVSIVDMADWEPDPEFRRLVAEA 301 +R G + G + + + + K +S ++ + +P + +V EA Sbjct: 903 KRYGKVIYA---QTGNYLNNVGIVTAPESEPTKKTTKLISAAELLELPENPAVKAIVDEA 959 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.136 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,316,435,351 Number of extensions: 96231466 Number of successful extensions: 243555 Number of sequences better than 1.0e-05: 2011 Number of HSP's gapped: 239201 Number of HSP's successfully gapped: 2062 Length of query: 392 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 254 Effective length of database: 1,760,596,133 Effective search space: 447191417782 Effective search space used: 447191417782 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 132 (55.5 bits)