BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0181.0003.p (588 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DAG5.1 B1DAG5_9BACL Histidine kinase internal region 715 0.0 B3KD30.1 B3KD30_9BACI Histidine kinase internal region 427 e-117 B3K539.1 B3K539_9BACI Histidine kinase internal region 416 e-114 B1DHH9.1 B1DHH9_9BACL Histidine kinase internal region 412 e-113 B1D8T7.1 B1D8T7_9BACL Signal transduction histidine kinase, LytS 344 2e-92 >B1DAG5.1 B1DAG5_9BACL Histidine kinase internal region Length = 582 Score = 715 bits (1846), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/553 (62%), Positives = 431/553 (77%), Gaps = 3/553 (0%) Query: 16 YTYSNNVTFDVVSKELQESNTKQLTFLSSQIDSRINQMMDFSVVFSKDPNVRKFNGLGIW 75 + YSNNV V+ KE++ SN KQL+FLSSQI+SRINQ MDF FSKDPNV+K+NGL IW Sbjct: 31 FAYSNNVATGVIGKEIRNSNIKQLSFLSSQIESRINQTMDFVFTFSKDPNVQKYNGLNIW 90 Query: 76 EDRYDRMQTRFVIQEKMMLQSGLTDVWPSRYAVYSQQNKDVISNYDKPTGYDENYLIQNM 135 +D YD MQTR+++ EKM LQSG+ ++WP + VYSQ +K+ +SN YDE+YL +N+ Sbjct: 91 DDNYDWMQTRYMVLEKMALQSGVVNIWPVEFTVYSQLHKEALSNSSTSVAYDEDYLKRNI 150 Query: 136 SGKWTYXXXXXXXXXXXKAFYWFHSDSIAPQGTLTGSDLVVEASFSSENIQNMLDTYKTG 195 S WTY AF W+++DS+ Q LTGS+LVV ASF S NIQNMLDTYK G Sbjct: 151 SKNWTYSEGATGTEGM--AFRWYYADSLGQQ-KLTGSNLVVGASFGSSNIQNMLDTYKEG 207 Query: 196 GQGDPFLYHKGETPILNRTADQKLTADLIRYLDKHSPDSSTQHVISLGHKNYLVSSVKSS 255 GQGDP Y G+ PILNR+A +L +L RYLD + S Q I L ++YLVS VKS Sbjct: 208 GQGDPLFYAPGQKPILNRSASPELAEELTRYLDGQKLEDSMQKTIKLNGQSYLVSLVKSP 267 Query: 256 YLEWYLVDVVPLDRILGPISVSRNLFYVSMLLLFVVGISASILLYQNVQRPIKKLIKGLR 315 LEWYLVD VPLD+ILGPIS SRNLFY++M LL V+G SI+LY++VQRPI KLI+GL+ Sbjct: 268 QLEWYLVDPVPLDQILGPISSSRNLFYLAMALLLVIGAFFSIVLYRDVQRPILKLIRGLK 327 Query: 316 RVQRGDYSVRLHSEDHNEFSFLFYRFNDMSHQIQDLIENVFNEKIRAREATLKQLQAQIN 375 +VQ GD+S R+H++ ++EF+FLFYRFNDMS QI+ LI+NV E++ A+EAT+KQLQAQIN Sbjct: 328 KVQLGDFSARIHAKANSEFTFLFYRFNDMSAQIETLIDNVLKERLIAQEATMKQLQAQIN 387 Query: 376 PHFLYNCLGFIINMAQMKDEEAVVSMAYNLSAYYRYTTRMERDTATLDDEVRLLVNYLDI 435 PHFLYNCLG++INMAQMKDEEAVV M Y+LS+YYRY TRME+ ++L DE++L+VNYLDI Sbjct: 388 PHFLYNCLGYMINMAQMKDEEAVVKMGYSLSSYYRYITRMEKPVSSLQDEIQLIVNYLDI 447 Query: 436 QKLRNGRIEYHIDIPQEMLSYSIPRLLLQPIVENSVIHGVGKSYSSGEIRISGECSGGCC 495 QK+RNGRI Y IDIP+EM +PRL+LQP+VEN+VIHGV KSYSSGEIRI+G+ GG Sbjct: 448 QKMRNGRIHYSIDIPEEMRGQQVPRLMLQPLVENAVIHGVSKSYSSGEIRIAGQIEGGFW 507 Query: 496 RVYIDDDGPGLSPEQQEALNRKMREPLQEEMGCGLWNTNQRLIHQFGNHSALHFTESPLG 555 R+++DDDGPGL E+ E +N+KMR P+Q++MG GLWNTNQR+IH FG S+L F+ S LG Sbjct: 508 RIFVDDDGPGLDGEKLELMNQKMRGPMQDDMGYGLWNTNQRIIHCFGPRSSLSFSSSELG 567 Query: 556 GFRTEIVWEIPAQ 568 GFRTEIVWEIP + Sbjct: 568 GFRTEIVWEIPKE 580 >B3KD30.1 B3KD30_9BACI Histidine kinase internal region Length = 578 Score = 427 bits (1099), Expect = e-117, Method: Compositional matrix adjust. Identities = 231/554 (41%), Positives = 338/554 (61%), Gaps = 13/554 (2%) Query: 16 YTYSNNVTFDVVSKELQESNTKQLTFLSSQIDSRINQMMDFSVVFSKDPNVRKFNGLGIW 75 Y YS+ V+ +VV ++E +LTF SQ+D+ I+Q+ +SV+ S D ++ + Sbjct: 27 YAYSHQVSINVVRSAVEEGQRNRLTFFMSQMDTMIDQLTKYSVIASNDDGIKSYLAERSG 86 Query: 76 EDRYDRMQTRFVIQEKMMLQSGLTDVWPSRYAVYSQQNKDVISNYDKPTGYDENYLIQNM 135 +R+ ++ I + + +Q T W S+ +Y Q +++++ D YD YL Sbjct: 87 STPMERIDSQQRITDMLNMQIA-TSSWDSQILMYLTQYRELLTT-DLSARYDAEYLAHAH 144 Query: 136 SGKWTYXXXXXXXXXXXKAFYWFHSDSIAPQGTLTGSDLVVEASFSSENIQNMLDTYKTG 195 WTY +AF+ + S + Q DL+VE F+ +N+ NML+ K Sbjct: 145 KQNWTYHRDSRG-----QAFFSWMRTSASSQ------DLIVEVRFTDQNLVNMLNRLKQD 193 Query: 196 GQGDPFLYHKGETPILNRTADQKLTADLIRYLDKHSPDSSTQHVISLGHKNYLVSSVKSS 255 G +PFLY T I N T+ ++ L++ ++ G Y+++ V SS Sbjct: 194 GDSEPFLYAPDGTVIANSTSVEETIRMAAGTLNELQLGEEGSRIVQSGQGKYVMNYVLSS 253 Query: 256 YLEWYLVDVVPLDRILGPISVSRNLFYVSMLLLFVVGISASILLYQNVQRPIKKLIKGLR 315 L WYLVD V LD + PI++S LFY+S+ LL V+ + ++LLY+NVQRPI +L+ +R Sbjct: 254 SLGWYLVDFVRLDSVYSPITLSSVLFYISVSLLLVLVLLLTLLLYRNVQRPISRLLHAVR 313 Query: 316 RVQRGDYSVRLHSEDHNEFSFLFYRFNDMSHQIQDLIENVFNEKIRAREATLKQLQAQIN 375 R++ G Y RL NEF +LF+ FN+M+ QI++LIE V+ E +R++EATLKQLQ+QIN Sbjct: 314 RIRDGQYMTRLKDVPKNEFMYLFHSFNNMAEQIEELIERVYKESLRSKEATLKQLQSQIN 373 Query: 376 PHFLYNCLGFIINMAQMKDEEAVVSMAYNLSAYYRYTTRMERDTATLDDEVRLLVNYLDI 435 PHFLYNCL +I NMA + D+EAVV+MA NL YYRYTTR+E+ TA L++EV+L+ NYL I Sbjct: 374 PHFLYNCLFYIKNMANLGDKEAVVAMALNLGEYYRYTTRLEKPTAPLEEEVKLVDNYLTI 433 Query: 436 QKLRNGRIEYHIDIPQEMLSYSIPRLLLQPIVENSVIHGVGKSYSSGEIRISGECSGGCC 495 Q LR R+ + I++P M+ IPRLLLQPIVEN+VIHGV I ISGE G C Sbjct: 434 QMLRLQRLTFEIEVPDSMMQLEIPRLLLQPIVENAVIHGVEDQLDFAMIHISGEIEGSRC 493 Query: 496 RVYIDDDGPGLSPEQQEALNRKMREPLQEEMGCGLWNTNQRLIHQFGNHSALHFTESPLG 555 R+ ID++G G+ + L R++ EPL E G GLWN +QRL+ ++G H+ L F+ESP G Sbjct: 494 RIRIDNNGQGMDVGIIDKLKRQVEEPLNESGGFGLWNIHQRLVTRYGKHAGLAFSESPSG 553 Query: 556 GFRTEIVWEIPAQE 569 G R EI WE+P++E Sbjct: 554 GLRVEICWEMPSRE 567 >B3K539.1 B3K539_9BACI Histidine kinase internal region Length = 596 Score = 416 bits (1068), Expect = e-114, Method: Compositional matrix adjust. Identities = 223/557 (40%), Positives = 328/557 (58%), Gaps = 13/557 (2%) Query: 16 YTYSNNVTFDVVSKELQESNTKQLTFLSSQIDSRINQMMDFSVVFSKDPNVRKFNGLGIW 75 Y YSN T +V+SKEL +SNT QL F +Q+++ I+ + + + DP++ F + + Sbjct: 25 YFYSNQTTTNVLSKELSQSNTNQLVFFQNQVNTNIDILASWPNLLLHDPDISSFRDIYL- 83 Query: 76 EDRY---DRMQTRFVIQEKMMLQSGLTDVWPSRYAVYSQQNKDVISNYDKPTGYDENYLI 132 +D+Y D + IQ K+ +Q ++ W S A+YS V++ D Y L Sbjct: 84 QDKYLNLDAINLVKQIQTKLSIQESSSN-WRSHLAIYSPSLGRVVTESDAGF-YSPEELA 141 Query: 133 QNMSGKWTYXXXXXXXXXXXKAFYWFHSDSIAPQGT--LTG-SDLVVEASFSSENIQNML 189 +++ W F W+ S+AP T TG S+ V++ F S NIQ+ML Sbjct: 142 EDVKPGWQVTPYYEGSDRRF-LFVWY---SVAPYSTQHRTGKSNTVIKVEFDSTNIQDML 197 Query: 190 DTYKTGGQGDPFLYHKGETPILNRTADQKLTADLIRYLDKHSPDSSTQHVISLGHKNYLV 249 D +K+ G+ DPF Y I NRTADQ+L ++ LD+ + V +G K Y V Sbjct: 198 DRFKSDGRSDPFYYKPDSGVIYNRTADQELINHMMAELDREPLEDVENRVKEVGGKTYSV 257 Query: 250 SSVKSSYLEWYLVDVVPLDRILGPISVSRNLFYVSMLLLFVVGISASILLYQNVQRPIKK 309 S V S WYL+D +PL I+ PI S LFY+S+ L ++ A+ LLY VQ PIK+ Sbjct: 258 SIVLSETTGWYLIDYIPLSDIMKPIHTSNRLFYISIAALLLMSCLAAYLLYSQVQVPIKQ 317 Query: 310 LIKGLRRVQRGDYSVRLHSEDHNEFSFLFYRFNDMSHQIQDLIENVFNEKIRAREATLKQ 369 L+ RR+Q GDY VR+ NEFSFL RFN M QIQ+L E+V+ EKI REA LKQ Sbjct: 318 LVYVFRRLQAGDYGVRMKVAGRNEFSFLATRFNSMVEQIQELFEHVYMEKIHVREAKLKQ 377 Query: 370 LQAQINPHFLYNCLGFIINMAQMKDEEAVVSMAYNLSAYYRYTTRMERDTATLDDEVRLL 429 LQ+QINPHF YNC FI +MA+++ EAVV+M+++LS Y+RYTTR ER+ L DEV + Sbjct: 378 LQSQINPHFFYNCFSFITSMAKLRKYEAVVAMSHSLSRYFRYTTRQERELVPLSDEVEFV 437 Query: 430 VNYLDIQKLRNGRIEYHIDIPQEMLSYSIPRLLLQPIVENSVIHGVGKSYSSGEIRISGE 489 +YL+IQ++R R++YH+ + +E IP L++QP+VEN+V+HG+ GEIR++ Sbjct: 438 THYLEIQQMRMRRLQYHLVLTEEAEGMEIPPLVIQPLVENAVLHGIEPHSGDGEIRVTFR 497 Query: 490 CSGGCCRVYIDDDGPGLSPEQQEALNRKMREPLQEEMGCGLWNTNQRLIHQFGNHSALHF 549 G + +DD+G G++ E+ L ++ P+ +EMGCG+WN +QR+ ++G + L F Sbjct: 498 IVNGLACIQVDDNGIGMNGEKLAELEARLNRPMDQEMGCGVWNVHQRMRLRYGEEAGLRF 557 Query: 550 TESPLGGFRTEIVWEIP 566 SP GG R + W +P Sbjct: 558 AASPQGGVRAVLYWPLP 574 >B1DHH9.1 B1DHH9_9BACL Histidine kinase internal region Length = 570 Score = 412 bits (1060), Expect = e-113, Method: Compositional matrix adjust. Identities = 213/549 (38%), Positives = 322/549 (58%), Gaps = 11/549 (2%) Query: 16 YTYSNNVTFDVVSKELQESNTKQLTFLSSQIDSRINQMMDFSVVFSKDPNVRKFNGLGIW 75 YTYSN + V+ E+Q T +L+ ++Q++S I Q+ + V +D +++++ Sbjct: 26 YTYSNRESVRVIENEIQSGTTNRLSSFAAQVESNIYQLSLYGVSIGQDSSIQEYQRPDFR 85 Query: 76 EDRYDRMQTRFVIQEKMMLQSGLTDVWPSRYAVYSQQNKDVISN-YDKPTGYDENYLIQN 134 E Y+R++ I EKM L + + W S ++ + D +S Y Y E+ + Sbjct: 86 EQPYERVKLSVAILEKMNLYNAASK-WHSTITLFFPRTGDALSTEYYNTITYREDAFTKP 144 Query: 135 MSGKWTYXXXXXXXXXXXKAFYWFHSDSIAPQGTLTGSDLVVEASFSSENIQNMLDTYKT 194 W Y +F W+ ++ + L+ + SF ++ MLD K Sbjct: 145 FLKSWEYTG---------DSFVWYATEPTTAMSNPRSARLITKISFPINHVTTMLDENKV 195 Query: 195 GGQGDPFLYHKGETPILNRTADQKLTADLIRYLDKHSPDSSTQHVISLGHKNYLVSSVKS 254 GDPFL++ + I N +A+ L L L + Y VS +KS Sbjct: 196 NNSGDPFLFNPEQGSIRNHSANSAKIDLLSEKLKSSKLGERGGFRTKLDNTEYYVSYIKS 255 Query: 255 SYLEWYLVDVVPLDRILGPISVSRNLFYVSMLLLFVVGISASILLYQNVQRPIKKLIKGL 314 L+WY VD VP+ +IL PI+ SRNLFY S+ +L V+ I+ ++Y++VQ P+ +L++G Sbjct: 256 DSLKWYYVDYVPMQQILSPITNSRNLFYTSIAVLLVMSIAVIFVIYRSVQVPLLQLVRGT 315 Query: 315 RRVQRGDYSVRLHSEDHNEFSFLFYRFNDMSHQIQDLIENVFNEKIRAREATLKQLQAQI 374 +R+ GD+SVRL NEFS L RFN M+ +IQ+LIENV+ EK+R REATLK LQ+QI Sbjct: 316 KRLSSGDFSVRLSHSGTNEFSLLLGRFNIMAQRIQELIENVYEEKLRRREATLKHLQSQI 375 Query: 375 NPHFLYNCLGFIINMAQMKDEEAVVSMAYNLSAYYRYTTRMERDTATLDDEVRLLVNYLD 434 NPHFLYNCL +I NMA+MK+E+AVV+MA NL Y+RY TR E D AT+ +E+ ++ NYL+ Sbjct: 376 NPHFLYNCLFYIKNMARMKNEKAVVAMALNLGDYFRYITRSENDVATIREELSMVTNYLE 435 Query: 435 IQKLRNGRIEYHIDIPQEMLSYSIPRLLLQPIVENSVIHGVGKSYSSGEIRISGECSGGC 494 IQ LR R+ + I++P E+++ +I RL LQPIVEN+++HG+ +GEIRI G G Sbjct: 436 IQSLRLERMRFAIEVPDELMNKTISRLTLQPIVENAIVHGLEPQAENGEIRIRGYAEDGM 495 Query: 495 CRVYIDDDGPGLSPEQQEALNRKMREPLQEEMGCGLWNTNQRLIHQFGNHSALHFTESPL 554 R+ ++D G G++ E+ + L + +PL + MGCG WN +QRLI+ FG + L +T S L Sbjct: 496 YRLVVEDSGIGMTDEEIQKLQLSLTKPLDDNMGCGTWNVHQRLIYLFGEGAGLSYTRSDL 555 Query: 555 GGFRTEIVW 563 GG +T I W Sbjct: 556 GGIKTTITW 564 >B1D8T7.1 B1D8T7_9BACL Signal transduction histidine kinase, LytS Length = 575 Score = 344 bits (882), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 190/548 (34%), Positives = 306/548 (55%), Gaps = 6/548 (1%) Query: 16 YTYSNNVTFDVVSKELQESNTKQLTFLSSQIDSRINQMMDFSVVFSKDPNVRKFNGLGIW 75 Y +SN + DVV E++ S K L++ ++Q D Q+ ++ ++D NVR L I Sbjct: 26 YWFSNKTSMDVVMNEVEISMHKDLSYFAAQTDETAEQLAKSGLMITEDINVRTLEFLEI- 84 Query: 76 EDRYDRMQTRFVIQEKMMLQSGLTDVWPSRYAVYSQQNKDVISNYDKPTGYDENYLIQNM 135 Y++ + I +K+ L + +D W + ++Y+ +S D YD++ + +N Sbjct: 85 ATLYEQTDQKIRIADKLRLINASSD-WDTTISIYAPATNTFVST-DFHLEYDKDLVTKNY 142 Query: 136 SGKWTYXXXXXXXXXXXKAFYWFHSDSIAPQGTLTGSDLVVEASFSSENIQNMLDTYKTG 195 S W Y F F S+ + G ++VE SFS++ + L+ +K G Sbjct: 143 SKVWKYTENVAPYYQNNPRFVRFLSEPYDSSSSNAG--VIVEVSFSADELVKALERFKAG 200 Query: 196 GQGDPFLYHKGETPILNRTADQKLTADLIRYLDKHSPDSSTQHVISLGHKNYLVSSVKSS 255 +GD F + + +D +L L+ ++ S I L Y V+SV Sbjct: 201 SKGDVFFSSPDQRILAVNGSDAELQKKLLAKVNLEKLSESQYTRIKLDGIEYTVNSVYMP 260 Query: 256 YLEWYLVDVVPLDRILGPISVSRNLFYVSMLLLFVVGISASILLYQNVQRPIKKLIKGLR 315 L WYL D +P+D ++ PI+ + NLFY+ ++ L + A+ +LY NVQ PI++LI+G++ Sbjct: 261 ELGWYLFDYLPIDDVVRPITANSNLFYICIVFLLIGSTIAAYVLYTNVQVPIRELIRGVK 320 Query: 316 RVQRGDYSVRLHSEDHNEFSFLFYRFNDMSHQIQDLIENVFNEKIRAREATLKQLQAQIN 375 ++++G+Y +NEF FL FNDM+ QI+ LI+NV+ E+IR+R+A LKQLQ+QIN Sbjct: 321 KLKKGEYPKLKVFHPNNEFHFLLVSFNDMASQIEQLIQNVYLEQIRSRDANLKQLQSQIN 380 Query: 376 PHFLYNCLGFIINMAQMKDEEAVVSMAYNLSAYYRYTTRMERDTATLDDEVRLLVNYLDI 435 PHFLYNC I ++ ++ ++E+V+ +A +LS YYRYTTR ER A L +E+ L+ +YL I Sbjct: 381 PHFLYNCFSLIRSLTRLGEKESVMELALHLSRYYRYTTRSERQLAYLREEIELVKSYLAI 440 Query: 436 QKLRNGRIEYHIDIPQEMLSYSIPRLLLQPIVENSVIHGVGKSYSSGEIRISGECSGGCC 495 Q + + Y I IP+ M IPRL+LQPIVEN+V+HG+ + GE++I+G + Sbjct: 441 QAMNVQDMTYVITIPEAMEELEIPRLILQPIVENAVLHGL-EPIGGGEVQITGSQNDRYN 499 Query: 496 RVYIDDDGPGLSPEQQEALNRKMREPLQEEMGCGLWNTNQRLIHQFGNHSALHFTESPLG 555 + + D+G G++ EQ L +M P E+ GC LWNT QR+ Q+G + + G Sbjct: 500 VITVTDNGVGVTEEQLAQLKLQMSMPPTEDKGCALWNTRQRMTLQYGQEAGVRLIRGDDG 559 Query: 556 GFRTEIVW 563 G E+ W Sbjct: 560 GLTVELYW 567 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.135 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,392,277,377 Number of extensions: 144902991 Number of successful extensions: 379007 Number of sequences better than 1.0e-05: 2011 Number of HSP's gapped: 376358 Number of HSP's successfully gapped: 2011 Length of query: 588 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 446 Effective length of database: 1,722,912,073 Effective search space: 768418784558 Effective search space used: 768418784558 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 134 (56.2 bits)