BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0181.0002.p (534 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DAG4.1 B1DAG4_9BACL Two component transcriptional regulator, A... 696 0.0 B1D8T6.1 B1D8T6_9BACL Two component transcriptional regulator, A... 385 e-105 B1DGI8.1 B1DGI8_9BACL Two component transcriptional regulator, A... 382 e-104 B1DHH8.1 B1DHH8_9BACL Two component transcriptional regulator, A... 362 7e-98 B3K540.1 B3K540_9BACI Response regulator receiver 322 7e-86 >B1DAG4.1 B1DAG4_9BACL Two component transcriptional regulator, AraC family Length = 535 Score = 696 bits (1796), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/533 (62%), Positives = 414/533 (77%) Query: 1 MIIVDDEAHWVDNLSMTKPWHTLGIEQVHKAYSASEALQIIETHPIDIVISDIQMPEMTG 60 ++IVDDEAHWV+NLSM KPWHTLGIE VH+AYSA EALQII T+PIDIVISD+ MPEMTG Sbjct: 3 LLIVDDEAHWVENLSMHKPWHTLGIEYVHRAYSAREALQIIGTNPIDIVISDVLMPEMTG 62 Query: 61 LELMEXXXXXXXXXXXXXLSGHSEFEFAKSAIQHSAVDYLLKPPTDSELLGAVQTAIAQL 120 +EL+E LSGH++FE+AK A++H AVDYLLKPPT+ ELLGA QTAI QL Sbjct: 63 IELIERIREQDKRIKCIILSGHADFEYAKEALRHHAVDYLLKPPTNEELLGAAQTAIDQL 122 Query: 121 NAEWELISSLERTQYTXXXXXXXXXXXXXXXXXXXXXMPADEWERKLENYGLPFRNGDCA 180 AEWE +SS ERTQ+ + +EW RKL+ YGLPFR+G CA Sbjct: 123 KAEWENVSSQERTQFALRENLPLLRGQLLLGAFRGERIAEEEWIRKLDMYGLPFRSGSCA 182 Query: 181 LMLVRLEEEFGQYKNNGQPLIEYAVINMAEEIIGECMEVWGVKEEHGYLVFLLQLKEKAA 240 L LVRLE+EFG Y+ NGQ L+EYA++N+AEEI+ E M VW VKEEHGYL FLLQ KE A Sbjct: 183 LALVRLEDEFGHYRGNGQHLVEYAIMNIAEEILQEFMGVWSVKEEHGYLAFLLQAKEHPA 242 Query: 241 DLGTDGLLEQLSVQLQYKVKQFLKGSLSIVITEWFRFPDQLPEQFRQASAYFRQIVGDER 300 D LLE+L++Q+Q KVKQFLKG++S+V+T+ F FP++LPEQ+RQA +YFRQIVGDE+ Sbjct: 243 VDRPDILLEKLAMQIQAKVKQFLKGAVSVVVTDSFLFPEELPEQYRQAVSYFRQIVGDEQ 302 Query: 301 EFVMRVSDLHEPSEQGPLDALYTPPSLINLLESGHWEAAGAKLMDVCAELDEKWPESWEH 360 EFVM+V + + G LD ++ P L+NL E+G WEAA KL EL++K ESWEH Sbjct: 303 EFVMKVDGTRKATAFGALDVIHGHPGLLNLAEAGRWEAAEDKLAAAFDELEDKGSESWEH 362 Query: 361 CMEAGFLITAAFSNLAHRNGHTLAKLLGTDIEELQSGEAFTSINKLRVWSLSVLGKLKEG 420 C+E G+ I++AF +LAHR+GHTLA L+G D+E LQSGEAF SI KLR WSL+ L KL+EG Sbjct: 363 CLEMGYTISSAFMHLAHRSGHTLADLIGPDMELLQSGEAFASIGKLRKWSLNALAKLREG 422 Query: 421 TSSEIKDIRSLYVKKIQEFTDKNLHLDVSLRVLADHVNLHPTHLSKIYKIETGEGISEYI 480 T+ + K+ RS YV+KI+++ DK+LHLDVSLR LAD+VNLHPTHLSKIYK+ETGEGIS+Y+ Sbjct: 423 TAHDAKNARSQYVQKIRDYVDKHLHLDVSLRALADYVNLHPTHLSKIYKLETGEGISDYV 482 Query: 481 SRLRMDRACHMLKTTGKKVYEISNDIGYMDPAYFIKVFKRQFGVTPQEYRDGK 533 + +RM+RACH+LK T KK+YEIS DIGY+DPAYFIKVFKRQF VTPQEYRDG+ Sbjct: 483 ASVRMERACHLLKATDKKIYEISADIGYLDPAYFIKVFKRQFDVTPQEYRDGR 535 >B1D8T6.1 B1D8T6_9BACL Two component transcriptional regulator, AraC family Length = 541 Score = 385 bits (990), Expect = e-105, Method: Compositional matrix adjust. Identities = 211/539 (39%), Positives = 324/539 (60%), Gaps = 13/539 (2%) Query: 1 MIIVDDEAHWVDNLSMTKPWHTLGIEQVHKAYSASEALQIIETHPIDIVISDIQMPEMTG 60 ++IVDD++ D+L+ PW G++ VHKAYS EA+ ++ H ID+VI+DI+MP MTG Sbjct: 4 LLIVDDQSILADDLADMLPWEEAGVDVVHKAYSGPEAIGLLHEHAIDVVITDIRMPGMTG 63 Query: 61 LELMEXXXXXXXXXXXXXLSGHSEFEFAKSAIQHSAVDYLLKPPTDSELLGAVQTAIAQL 120 LEL++ LSG+S+FE+ K A++ + DYLLKP +D ELL +V+ AI +L Sbjct: 64 LELIQEIKQNWKHTKCILLSGYSDFEYTKQALKLKSSDYLLKPASDDELLTSVRRAIKEL 123 Query: 121 NAEWELISSLERTQYTXXXXX-XXXXXXXXXXXXXXXXMPADEWERKLENYGLPFR-NGD 178 EW ISS++R Y+ + +KL Y +PF+ N D Sbjct: 124 EQEWLEISSMQRAMYSLREQLPKLREYLLLDMLSGKQSLSPQRLSKKLATYTVPFQENDD 183 Query: 179 CALMLVRLEEEFGQYKNN-GQPLIEYAVINMAEEIIGECMEVWGVKEEHGYLVFLLQLKE 237 +ML+R+++E Y + + LI+YA+ N+AEE+ G+ +++W K+ +G++V L LK Sbjct: 184 FHVMLLRIDDEDRLYDDGESEALIDYALANIAEEVFGDQLDMWHCKDSNGFIVCL--LKA 241 Query: 238 KAADLGTDGL---LEQLSVQLQYKVKQFLKGSLSIVITEWFRFPDQLPEQFRQASAYFRQ 294 KA T L +E + QLQ+ VK +LK +SI+ ++ FP + ++ + FRQ Sbjct: 242 KAGSTITSDLDEWIESHAFQLQHVVKSYLKVGISILTSKRGSFPQDVGPLYQTSITNFRQ 301 Query: 295 IVGDEREFVMRVSDLHEPSEQGP--LDALYTPPSLINLLESGHWEAAGAKLMDVCAELDE 352 +G E+E VS EP+ P L LY PPS++ +LE G W+AAG KL + E++E Sbjct: 302 FIGSEQELF--VSLAKEPTRGTPQLLGELYRPPSVLQMLELGQWDAAGEKLEAIFREIEE 359 Query: 353 KWPESWEHCMEAGFLITAAFSNLAHRNGHTLAKLLGTDIEELQSGEAFTSINKLRVWSLS 412 +W S EH +EA F I A + LAH+N L+ ++G D +G +++ LR W+ Sbjct: 360 EWRGSQEHVLEAYFSIAATLAALAHKNKKWLSDMIGDDFHAFANGSPIHTVDDLRTWTAR 419 Query: 413 VLGKLKEGTSSEIKDIRSLYVKKIQEFTDKNLHLDVSLRVLADHVNLHPTHLSKIYKIET 472 + ++ +SE KD RS ++K+QEF +L SL ++ HV L+P++LSKIYK ET Sbjct: 420 TIDSYRKSVNSEDKDSRSSIIRKVQEFIHNHLE-QASLHSISTHVYLNPSYLSKIYKTET 478 Query: 473 GEGISEYISRLRMDRACHMLKTTGKKVYEISNDIGYMDPAYFIKVFKRQFGVTPQEYRD 531 GEGISEY+ R RM+++ +L T +K+YEIS +GY P+YFI++FK+ FG+TPQEYR+ Sbjct: 479 GEGISEYLLRARMEKSADLLAQTDEKIYEISVMLGYQKPSYFIQLFKKHFGITPQEYRN 537 >B1DGI8.1 B1DGI8_9BACL Two component transcriptional regulator, AraC family Length = 539 Score = 382 bits (982), Expect = e-104, Method: Compositional matrix adjust. Identities = 210/536 (39%), Positives = 310/536 (57%), Gaps = 5/536 (0%) Query: 1 MIIVDDEAHWVDNLSMTKPWHTLGIEQVHKAYSASEALQIIETHPIDIVISDIQMPEMTG 60 ++IVDDEAH VD L+ T W ++GI+QV+KAYS EAL+ + IDIVI+DI+MP M+G Sbjct: 4 LLIVDDEAHVVDRLATTVDWESVGIDQVYKAYSGQEALEQLHQFSIDIVITDIRMPGMSG 63 Query: 61 LELMEXXXXXXXXXXXXXLSGHSEFEFAKSAIQHSAVDYLLKPPTDSELLGAVQTAIAQL 120 L+L+ LSG+SEF +AK A+Q DYLLKP S+LL V+ + +L Sbjct: 64 LQLISEIKRQWPKTKSILLSGYSEFNYAKQAMQFQTEDYLLKPVKTSDLLSTVERVLRKL 123 Query: 121 NAEWELISSLERTQYTXXXXXXXXXXXXXXXXXXXXXMPADEWERKLENYGLPFRN-GDC 179 EWE + S +R YT K+ L R+ Sbjct: 124 KQEWEEVISAQRITYTLKEHLPLLRANLLQELLQGKLWSKQTLREKMTRLELGDRDWQRF 183 Query: 180 ALMLVRLEEEFGQYKNNGQPLIEYAVINMAEEIIGECMEVWGVKEEHGYLVFLLQLKEKA 239 +LM VRL++ FG++ EYAV NMAEE+ G +W K+ H YLVFLL LK++A Sbjct: 184 SLMAVRLDDRFGEFTEEDLSWKEYAVANMAEELFGGRYSLWHAKDAHDYLVFLLTLKDEA 243 Query: 240 ADLGTD-GLLEQLSVQLQYKVKQFLKGSLSIVITEWFRFPDQLPEQFRQASAYFRQIVGD 298 G D G LE+ + LQ V +LKG +S++++ FP+ +P + ++ FR +G Sbjct: 244 E--GDDPGWLERTASVLQSAVGVYLKGKVSVMVSSAGAFPEDVPGFYNRSITAFRNRIGQ 301 Query: 299 EREFVMRVSDLH-EPSEQGPLDALYTPPSLINLLESGHWEAAGAKLMDVCAELDEKWPES 357 E E MR+ + EP+ LD LY PP+LI+LLE+ WEA + + ++ S Sbjct: 302 EPEQFMRLEEKESEPAAIRSLDCLYEPPALIHLLEAARWEAVEERYKRIFTGVESGETVS 361 Query: 358 WEHCMEAGFLITAAFSNLAHRNGHTLAKLLGTDIEELQSGEAFTSINKLRVWSLSVLGKL 417 EH +E F + +A++ +AH+NG L + LGTD + +G ++ LR W+ L L Sbjct: 362 EEHLLEIYFTVASAYAYIAHKNGRLLNETLGTDYNRMATGMPLRTVQHLREWAFRTLKAL 421 Query: 418 KEGTSSEIKDIRSLYVKKIQEFTDKNLHLDVSLRVLADHVNLHPTHLSKIYKIETGEGIS 477 +E + E KD R +++I+ F D N+ D+SL+ +AD+V LHP ++SK+YK+ETGE +S Sbjct: 422 QEDMAKETKDNRHSLIERIRSFIDDNVTGDISLQSVADYVKLHPVYVSKVYKLETGENLS 481 Query: 478 EYISRLRMDRACHMLKTTGKKVYEISNDIGYMDPAYFIKVFKRQFGVTPQEYRDGK 533 +YI R++M+ A ML+ + +KVY I+ +GY P FI FK+ FG+TPQEYRDG+ Sbjct: 482 DYIQRVKMEEAQSMLRRSDEKVYVIAARLGYQRPHSFISAFKKTFGMTPQEYRDGQ 537 >B1DHH8.1 B1DHH8_9BACL Two component transcriptional regulator, AraC family Length = 542 Score = 362 bits (928), Expect = 7e-98, Method: Compositional matrix adjust. Identities = 196/535 (36%), Positives = 307/535 (57%), Gaps = 6/535 (1%) Query: 1 MIIVDDEAHWVDNLSMTKPWHTLGIEQVHKAYSASEALQIIETHPIDIVISDIQMPEMTG 60 +++VDDE V+ L+ T PW GI VH+A S ALQI+E H IDIVI+DI+MP M+G Sbjct: 4 LLLVDDERSVVETLAETIPWEECGISVVHEALSGPIALQIMEDHAIDIVITDIKMPGMSG 63 Query: 61 LELMEXXXXXXXXXXXXXLSGHSEFEFAKSAIQHSAVDYLLKPPTDSELLGAVQTAIAQL 120 +EL+ L+G+++F++AK AI + DYLLKP +D +L+ +V+ + Q+ Sbjct: 64 IELITAINSKWPHVRTILLTGYADFDYAKQAIAQNTFDYLLKPVSDEDLIDSVERVVKQI 123 Query: 121 NAEWELISSLERTQYTXXXXXXXXXXXXXXXXXXXXXMPADEWERKLENYGLPFRNGD-C 179 +WE ++S +T YT A KL LPF D Sbjct: 124 KEKWEEVASYRKTLYTLNENLPLLRANTLNELLRGSNQSA--LADKLALLELPFAEDDGV 181 Query: 180 ALMLVRLEEEFGQYKNNGQPLIEYAVINMAEEIIGECMEVWGVKEEHGYLVFLLQLKEKA 239 +ML+R+EE F + L+EYA+ N+ EI+ +W ++ H Y+V +++ K A Sbjct: 182 CMMLIRMEERFAEMPGQDSALMEYAICNITSEIMQNDYHIWHARDAHDYIVLIVKPKNTA 241 Query: 240 -ADLGTDGLLEQLSVQLQYKVKQFLKGSLSIVITEWFRFPDQLPEQFRQASAYFRQIVGD 298 AD+ LLE+ + Q+Q V+ +LKG++S+++ FP Q+ E + A R+ +G Sbjct: 242 VADMEARSLLERYAAQIQTNVQNYLKGAISVLVGGQGTFPGQVKEIYEHAVTSMRRKMGH 301 Query: 299 EREFVMRVSDLHEPSEQGPLDALYTPPSLINLLESGHWEAAGAKLMDVCAELDEKWPES- 357 + + + + S + +LY PP+LI+LL++G ++ K+ + ++ E E Sbjct: 302 GKGLFVTTQEALDSSPMNTVWSLYEPPTLISLLDAGRFDDVETKIRHIFRDMLETGGEQD 361 Query: 358 -WEHCMEAGFLITAAFSNLAHRNGHTLAKLLGTDIEELQSGEAFTSINKLRVWSLSVLGK 416 E +EA ++ AFS + H+NG L+ +L + + A+T+ +L WS+ +L Sbjct: 362 MSEQLIEAYHVLAGAFSYIIHKNGKLLSSVLSPEALKFFHAPAYTTAAQLMEWSIRILQG 421 Query: 417 LKEGTSSEIKDIRSLYVKKIQEFTDKNLHLDVSLRVLADHVNLHPTHLSKIYKIETGEGI 476 ++E E+KD S V+ ++ F D NL DVSL +ADHV+LHP +LSKIYK ETGE + Sbjct: 422 IREDADQELKDNHSTIVRAVRSFIDANLAKDVSLPAIADHVHLHPVYLSKIYKAETGEPL 481 Query: 477 SEYISRLRMDRACHMLKTTGKKVYEISNDIGYMDPAYFIKVFKRQFGVTPQEYRD 531 +EY+ RLRM++A +L+TT KV+EIS +GY + AYFI+VFK+ F VTPQEYRD Sbjct: 482 TEYVYRLRMEKAAFLLRTTPSKVFEISEIVGYNNTAYFIRVFKKFFDVTPQEYRD 536 >B3K540.1 B3K540_9BACI Response regulator receiver Length = 545 Score = 322 bits (824), Expect = 7e-86, Method: Compositional matrix adjust. Identities = 192/542 (35%), Positives = 297/542 (54%), Gaps = 14/542 (2%) Query: 1 MIIVDDEAHWVDNLSMTKPWHTLGIEQVHKAYSASEALQIIETHPIDIVISDIQMPEMTG 60 +++VDDE++ ++L T PW L IE+V++A SA EA+ ++E ID+V++D++MP MTG Sbjct: 3 ILLVDDESYVTESLYQTIPWRELDIEEVYQASSALEAIDLLEEQDIDVVVTDVRMPVMTG 62 Query: 61 LELMEXXXXXXXXXXXXXLSGHSEFEFAKSAIQHSAVDYLLKPPTDSELLGAVQTAIAQL 120 LELME L+G+S+FE+AK AI+ A DY+LKP D E + +V + +A + Sbjct: 63 LELMETITERWTHIRCILLTGYSDFEYAKQAIRLQASDYILKPVDDGEFMRSVSSVLASI 122 Query: 121 NAEWELISSLERTQYTXXXXXXXXXXXXXXXXXXXXXMPADEWERKLENYGLPFRNGDCA 180 E + + + Y+ MP + KL Y +P R Sbjct: 123 QEERKELGHFHQLMYSRKSDLGILRNSLMHDLLLGREMPRHSLDHKLHEYEIPLRTDQRT 182 Query: 181 LML-VRLEEEFGQYKNNGQPLIEYAVINMAEEIIGECMEVWGVKEEHGYLVFLLQLKE-- 237 +ML ++L + F + L+EYA+ N+AEE+ E + VW K H L+ L Q K Sbjct: 183 IMLLIQLGQRFTGMDDYSVGLMEYAIGNIAEEVFAELLHVWSCKTPHHCLILLAQPKRVP 242 Query: 238 KAADLGT---DGLLEQLSVQLQYKVKQFLKGSLSIVITEWFRFPDQLPEQFRQA-SAYFR 293 A D+ T L++ Q Q V +LKGS+S+ +++ F FP +L +R S+ + Sbjct: 243 NAGDMETFADSRELKRYITQFQQDVGSYLKGSISVFVSDSFDFPGELGSVYRSGLSSLYL 302 Query: 294 QIVGDEREFVMRVSDLHEPSEQGPL----DALYTPPSLINLLESGHWEAAGAKLMDVCAE 349 GD +R ++ H+ P+ A PPSL++LLE+ W+AA K+ V AE Sbjct: 303 WGNGDHE--AIRFAEDHDDRLHEPVWDVTQAFAKPPSLLHLLETRQWDAARDKIEQVFAE 360 Query: 350 LDEKWPESWEHCMEAGFLITAAFSNLAHRNGHTLAKLLGTDIEELQSGEAFTSINKLRVW 409 ++ + E + AF LAH+ GH + +L + L + S KLR W Sbjct: 361 VETAFI-GQTALYEIFLSVANAFMYLAHKQGHYIHQLDQAGWDPLYIQQVVQSAAKLRSW 419 Query: 410 SLSVLGKLKEGTSSEIKDIRSLYVKKIQEFTDKNLHLDVSLRVLADHVNLHPTHLSKIYK 469 SL +L KL +S + +S +K++QE D+S++ +AD V LHP +LSKIYK Sbjct: 420 SLDMLNKLHVISSEQETTSKSHIIKQVQEMVTAYSGHDLSVKTIADRVFLHPVYLSKIYK 479 Query: 470 IETGEGISEYISRLRMDRACHMLKTTGKKVYEISNDIGYMDPAYFIKVFKRQFGVTPQEY 529 ETGEG+ +YI R RM+RA ++LK T KK+YEI+ ++GY +P YF K+F++ +G+TP EY Sbjct: 480 SETGEGLGDYIIRKRMERALYLLKHTNKKIYEITAELGYQNPQYFSKMFRKHYGMTPNEY 539 Query: 530 RD 531 RD Sbjct: 540 RD 541 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.135 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,981,501,164 Number of extensions: 117335408 Number of successful extensions: 378247 Number of sequences better than 1.0e-05: 3514 Number of HSP's gapped: 381823 Number of HSP's successfully gapped: 3979 Length of query: 534 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 393 Effective length of database: 1,732,333,088 Effective search space: 680806903584 Effective search space used: 680806903584 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 134 (56.2 bits)