BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0178.0005.p (208 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B7DSV9.1 B7DSV9_9BACL BioY protein 130 9e-29 C1PVG4.1 C1PVG4_ALIAC Uncharacterized conserved protein 129 1e-28 Q9RRL8.1 Q9RRL8_DEIRA Biotin synthase, putative 120 8e-26 B0KAP5.1 B0KAP5_THEP3 BioY protein 117 8e-25 C1YLP6.1 C1YLP6_NOCDA Uncharacterized conserved protein 116 1e-24 >B7DSV9.1 B7DSV9_9BACL BioY protein Length = 197 Score = 130 bits (326), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 74/184 (40%), Positives = 104/184 (56%), Gaps = 4/184 (2%) Query: 11 TTRGLIFSALFAGVMIALSYLRISLPFSTVPITMQTLAVMLAGSMLGARYGSXXXXXXXX 70 RGLIF ALF + LS ++I P +VPIT++TL V + +LG YG+ Sbjct: 3 KVRGLIFCALFIAIFAVLSLVQI--PVGSVPITLETLVVQVCAGLLGPWYGALTFVLLIV 60 Query: 71 XXXXXFPVLAGSGGLSVLTGPTAGYIFSWPVVAFLIGLFAQRIEQ-NKYTFVKLLAVNFL 129 P++ G G S++ GPTAGYI+ WP A GL R+ ++ KL+A+ F+ Sbjct: 61 LDLIGLPLIGGHAGPSLMLGPTAGYIWGWPFCALFAGLAIARVRPGSRGEIAKLIAILFV 120 Query: 130 FGVLLVYPGGVWWLAHST-GMTSLSKALTAGMWPFIPGDLIKAVLSAAVVTAVWRVYPIE 188 G L+ Y GV WL H + + AL G+WPF+PGD +K+VL+A +V V RVYP E Sbjct: 121 LGDLVCYIPGVLWLRHVVPSLHPWASALAGGVWPFLPGDFVKSVLAAVIVARVRRVYPTE 180 Query: 189 RILN 192 R+L Sbjct: 181 RLLR 184 >C1PVG4.1 C1PVG4_ALIAC Uncharacterized conserved protein Length = 197 Score = 129 bits (325), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 74/184 (40%), Positives = 103/184 (55%), Gaps = 4/184 (2%) Query: 11 TTRGLIFSALFAGVMIALSYLRISLPFSTVPITMQTLAVMLAGSMLGARYGSXXXXXXXX 70 RGLIF ALF + LS ++I P +VPIT++TL V + +LG YG+ Sbjct: 3 KVRGLIFCALFIAIFAVLSLVQI--PVGSVPITLETLVVQVCAGLLGPWYGALTFVLLIV 60 Query: 71 XXXXXFPVLAGSGGLSVLTGPTAGYIFSWPVVAFLIGLFAQRIEQ-NKYTFVKLLAVNFL 129 P++ G G S++ GPTAGYI+ WP A GL R+ ++ KL+A+ F+ Sbjct: 61 LDLIGLPLIGGHAGPSLMLGPTAGYIWGWPFCALFAGLAIARVRPGSRGEIAKLIAILFV 120 Query: 130 FGVLLVYPGGVWWLAHST-GMTSLSKALTAGMWPFIPGDLIKAVLSAAVVTAVWRVYPIE 188 G L+ Y GV WL H + AL G+WPF+PGD +K+VL+A +V V RVYP E Sbjct: 121 LGDLVCYIPGVLWLRHVVPSLHPWGSALAGGVWPFLPGDFVKSVLAAVIVARVRRVYPTE 180 Query: 189 RILN 192 R+L Sbjct: 181 RLLR 184 >Q9RRL8.1 Q9RRL8_DEIRA Biotin synthase, putative Length = 229 Score = 120 bits (301), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 73/181 (40%), Positives = 107/181 (59%), Gaps = 4/181 (2%) Query: 11 TTRGLIFSALFAGVMIALSYLRISLPFSTVPITMQTLAVMLAGSMLGARYGSXXXXXXXX 70 TT+ +++ ALFA +M AL+ + + VPI+ Q L MLAG++LGAR G+ Sbjct: 44 TTKDIVYIALFAAIMAALAVVPPITLATGVPISAQALGPMLAGAVLGARRGALSMVLFLV 103 Query: 71 XXXXXFPVL-AGSGGLSVLTGPTAGYIFSWPVVAFLIGLFAQRIEQNKYTFVKLLAVNFL 129 P+L G GG+S GPTAG++ SWP+ AF+IGL +R + F A+ F+ Sbjct: 104 LVAAGLPLLVGGRGGISAFAGPTAGFLISWPIAAFVIGLLVER-NWARLNFALAFAIIFV 162 Query: 130 FGVLLVYPGGVWWLAHSTGMTSLSKALTAGMWPFIPGDLIKAVLSAAVVTAVWRVYPIER 189 V+++Y G WL++S M+ L + AG PF+PGDL+K+VL+A V V R YPI R Sbjct: 163 SSVVIMYGIGNAWLSYSAPMSYLKATIAAG--PFLPGDLLKSVLAALVAVTVKRSYPIIR 220 Query: 190 I 190 + Sbjct: 221 V 221 >B0KAP5.1 B0KAP5_THEP3 BioY protein Length = 182 Score = 117 bits (292), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 70/165 (42%), Positives = 95/165 (57%), Gaps = 5/165 (3%) Query: 12 TRGLIFSALFAGVMIALSYLRISLPFSTVPITMQTLAVMLAGSMLGARYGSXXXXXXXXX 71 T+ +I ++LFA + + +++I LPFS VPIT QT AVMLAG +L Sbjct: 4 TKDMILASLFAAITFIMGFVKIPLPFSPVPITGQTFAVMLAGGLLNPTSAFLSLFIFDLL 63 Query: 72 XXXXFPVLAG-SGGLSVLTGPTAGYIFSWPVVAFLIGLFAQRIEQNKYTFVKLLAVNFLF 130 PV AG +GGL++L GPT GYI SWP AFLI L ++ K F+ + LF Sbjct: 64 GAIGIPVFAGLTGGLNILIGPTGGYILSWPFAAFLISL---TLKNKKANFINIFISYLLF 120 Query: 131 GVLLVYPGGVWWLAHSTGMTSLSKALTAGMWPFIPGDLIKAVLSA 175 ++ VY GV L+ TG+ KA+ AG PFIPGDLIKA +++ Sbjct: 121 AIIFVYILGVTQLSFVTGI-PFKKAILAGALPFIPGDLIKAFIAS 164 >C1YLP6.1 C1YLP6_NOCDA Uncharacterized conserved protein Length = 210 Score = 116 bits (291), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 77/186 (41%), Positives = 108/186 (58%), Gaps = 7/186 (3%) Query: 8 KKWTTRGLIFSALFAGVMIALSY-LRISLPFSTVPITMQTLAVMLAGSMLGARYGSXXXX 66 + T R L A+FAG++ ALS + I LPFS VPIT+QTL +MLA S+LG + G Sbjct: 11 RGLTARDLALIAVFAGLIAALSVTVAIPLPFSPVPITLQTLGIMLAPSLLGWKRGPLAVA 70 Query: 67 XXXXXXXXXFPVLAGS-GGLSVLTGPTAGYIFSWPVVAFLIGLFAQ---RIEQNKYTFVK 122 P+ AG GG+ VL P+AG+I SW A +IGL R + +Y F Sbjct: 71 AFIVLGLAGLPLFAGGMGGVGVLARPSAGFIVSWVFAALVIGLLTDLMVRGSRGRYRFWA 130 Query: 123 LLAVNFLFGVLLVYPGGVWWLAHSTGMTSLSKALTAGMWPFIPGDLIKAVLSAAVVTAVW 182 L +N + G+L++Y GV W+A G L+ A + M F+PGDL+KAV++A + +AV+ Sbjct: 131 GLGINVVGGILVIYAIGVPWMAVVMGDGVLAAAYS--MVAFLPGDLVKAVVTALIASAVY 188 Query: 183 RVYPIE 188 R YPI Sbjct: 189 RAYPIP 194 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.325 0.138 0.433 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,137,881,758 Number of extensions: 41467986 Number of successful extensions: 150031 Number of sequences better than 1.0e-05: 793 Number of HSP's gapped: 148673 Number of HSP's successfully gapped: 795 Length of query: 208 Length of database: 3,060,696,203 Length adjustment: 130 Effective length of query: 78 Effective length of database: 1,835,964,253 Effective search space: 143205211734 Effective search space used: 143205211734 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 128 (53.9 bits)