BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0176.0015.p (504 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B8I5W2.1 B8I5W2_CLOCE IMP dehydrogenase/GMP reductase 792 0.0 Q185K9.1 Q185K9_CLOD6 Inosine-5'-monophosphate dehydrogenase EC=... 767 0.0 C0Z4B5.1 C0Z4B5_BREBN Inosine-5'-monophosphate dehydrogenase EC=... 764 0.0 B0NHI2.1 B0NHI2_EUBSP Putative uncharacterized protein 750 0.0 Q92FC7.1 Q92FC7_LISIN Lin0179 protein 748 0.0 >B8I5W2.1 B8I5W2_CLOCE IMP dehydrogenase/GMP reductase Length = 500 Score = 792 bits (2046), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/503 (73%), Positives = 441/503 (87%), Gaps = 3/503 (0%) Query: 1 MAYYYDQPSRTFSEFLLVPNLTTKECIPGNVDLRTPVTKFRKGETPALTMNLPVTSAVMQ 60 MA+YY++PSRTFSE+LLVPNL+TKEC+P NV L+TPV K + GE L +N+PV SA+MQ Sbjct: 1 MAFYYNEPSRTFSEYLLVPNLSTKECVPDNVILKTPVVKHKVGEKSTLELNIPVVSAIMQ 60 Query: 61 AVSDHNMAIALAKSGGISFIYGSQSVEQQVEMVRRVKKFKAGFVLSDSNLRPEDTLKDVL 120 +VSD NMAIALAK GGISFIYGSQS+E Q EMVR+VKK+KAGFV+SDSNLRP++ L+DV+ Sbjct: 61 SVSDQNMAIALAKCGGISFIYGSQSIESQAEMVRKVKKYKAGFVVSDSNLRPDNKLRDVV 120 Query: 121 ELKARSGHSTIAITDNGEPTGQLMGIVTSRDYRENRLPPDCRITEFMTPLSSLIYAREGI 180 +K ++GHSTIAIT++G PTG+L+GIVTSRDYR +R D I+ FMTP S LIY E Sbjct: 121 AMKQKTGHSTIAITEDGTPTGKLLGIVTSRDYRLSRASLDEEISTFMTPFSHLIYGNEKT 180 Query: 181 TLTEANDMIWDHKLNCLPIVNSSGNLVHLVFRKDYDSHQEYPLELHDSNKQLIVGAGINS 240 TL EAND+IW+HKLNCLPI++S+ L++ VFRKDYDSH++ P EL D +K LIVGAGIN+ Sbjct: 181 TLKEANDLIWEHKLNCLPIIDSNQKLMYFVFRKDYDSHKQNPNELLDKSKSLIVGAGINT 240 Query: 241 RDYKERVPALVEAGADVLCIDSSDGYSEWQAETIHYIKETFGDNVKVGAGNVVDKEGFLY 300 RDYKERV ALVEAG D++CIDSSDGYSEWQ++TI +IKET+ VKVGAGNVVD+EGF Y Sbjct: 241 RDYKERVAALVEAGVDIVCIDSSDGYSEWQSDTIKWIKETYNGQVKVGAGNVVDREGFRY 300 Query: 301 LVEAGADFIKVGIGGGSICITREQKGIGRGQASSVIEVAAARQEYYEQTGIYVPICSDGG 360 LV+AGADFIKVGIGGGSICITREQKGIGRGQAS+VIEV++AR EY ++TGIYVPICSDGG Sbjct: 301 LVDAGADFIKVGIGGGSICITREQKGIGRGQASAVIEVSSARDEYMKETGIYVPICSDGG 360 Query: 361 IVHDYHIVLALAMGADFVMLGRYFARFDESPGRKLLVGGNFVKEYWGEGSSRARNWQRYD 420 IVHDYH+VLALAMGADF+MLGRYFARFDESP RKL VGGNFVKEYWGEGS+RARNWQRYD Sbjct: 361 IVHDYHMVLALAMGADFIMLGRYFARFDESPTRKLKVGGNFVKEYWGEGSNRARNWQRYD 420 Query: 421 FGNADKESKLEFEEGVDSFIPYAGRLKDNLDLSISKIKSTMCNCGALTIPQLQQQAKITL 480 G ++KL FEEGVDS++PYAG+LKDNLD +I KIKSTMCNCGAL++ +LQQ+A+ITL Sbjct: 421 MGG---DAKLGFEEGVDSYVPYAGKLKDNLDTTIYKIKSTMCNCGALSVSELQQKARITL 477 Query: 481 VSSTTIYEGGAHDVMLKEKDRSS 503 VS+T+I EGGAHDV+LK+K+ SS Sbjct: 478 VSATSIKEGGAHDVILKDKEISS 500 >Q185K9.1 Q185K9_CLOD6 Inosine-5'-monophosphate dehydrogenase EC=1.1.1.205 Length = 499 Score = 767 bits (1980), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/498 (69%), Positives = 436/498 (87%), Gaps = 3/498 (0%) Query: 1 MAYYYDQPSRTFSEFLLVPNLTTKECIPGNVDLRTPVTKFRKGETPALTMNLPVTSAVMQ 60 MA+Y+D PS TFSE+LLVP ++ +CIP NV L+TPVTKF+KGE + MN+P+TSA+MQ Sbjct: 1 MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGEEADIYMNIPLTSAIMQ 60 Query: 61 AVSDHNMAIALAKSGGISFIYGSQSVEQQVEMVRRVKKFKAGFVLSDSNLRPEDTLKDVL 120 +VSD MAIALAK GGISFIYGSQ++E + MV RVK KAGFV+SDSN++P++TLKD+L Sbjct: 61 SVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAGFVVSDSNIKPDNTLKDIL 120 Query: 121 ELKARSGHSTIAITDNGEPTGQLMGIVTSRDYRENRLPPDCRITEFMTPLSSLIYAREGI 180 +LK ++GHST+A+T++G TG+L+GIV SRDYR +R+ D +++EFMTP+SS++YA + + Sbjct: 121 DLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLDTKVSEFMTPMSSIVYANKDV 180 Query: 181 TLTEANDMIWDHKLNCLPIVNSSGNLVHLVFRKDYDSHQEYPLELHDSNKQLIVGAGINS 240 TL EAN++IWDHKLN LP+++ +GNL+++VFRKDY SH+E PLEL DS+K+ +VGAGIN+ Sbjct: 181 TLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSHKENPLELLDSSKRYVVGAGINT 240 Query: 241 RDYKERVPALVEAGADVLCIDSSDGYSEWQAETIHYIKETFGDNVKVGAGNVVDKEGFLY 300 RD+ ERVPALVEAGADVLCIDSS+G+SEWQ T+ +I+E +GD VKVGAGNVVD+EGFLY Sbjct: 241 RDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDFIREKYGDTVKVGAGNVVDREGFLY 300 Query: 301 LVEAGADFIKVGIGGGSICITREQKGIGRGQASSVIEVAAARQEYYEQTGIYVPICSDGG 360 L EAGADF+KVGIGGGSICITREQKGIGRGQA+S+IEVA AR EY+E+TGIY+PICSDGG Sbjct: 301 LAEAGADFVKVGIGGGSICITREQKGIGRGQATSIIEVAQARDEYFEKTGIYIPICSDGG 360 Query: 361 IVHDYHIVLALAMGADFVMLGRYFARFDESPGRKLLVGGNFVKEYWGEGSSRARNWQRYD 420 IV+D+HI LALAMGADF+MLGRYF+RFDESP K+ + G+++KEYWGEGS+RARNWQRYD Sbjct: 361 IVYDHHITLALAMGADFIMLGRYFSRFDESPTNKVNINGSYMKEYWGEGSARARNWQRYD 420 Query: 421 FGNADKESKLEFEEGVDSFIPYAGRLKDNLDLSISKIKSTMCNCGALTIPQLQQQAKITL 480 G + KL FEEGVDS++PYAG LKDN+ LS+SK++STMCNCGAL+IP+LQ+ AK+TL Sbjct: 421 LGG---DKKLSFEEGVDSYVPYAGSLKDNVTLSLSKVRSTMCNCGALSIPELQKNAKLTL 477 Query: 481 VSSTTIYEGGAHDVMLKE 498 VSST+I EGGAHDVMLK+ Sbjct: 478 VSSTSIVEGGAHDVMLKD 495 >C0Z4B5.1 C0Z4B5_BREBN Inosine-5'-monophosphate dehydrogenase EC=1.1.1.205 Length = 499 Score = 764 bits (1973), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/498 (70%), Positives = 429/498 (86%), Gaps = 5/498 (1%) Query: 1 MAYYYDQPSRTFSEFLLVPNLTTKECIPGNVDLRTPVTKFRKGETPALTMNLPVTSAVMQ 60 MA+YY +PSRTF+EFLL+PNLTTKEC P NVDL TP+TK++KGE PA+++N+P +SAVMQ Sbjct: 1 MAFYYTEPSRTFNEFLLLPNLTTKECTPNNVDLSTPITKYKKGEKPAISLNIPFSSAVMQ 60 Query: 61 AVSDHNMAIALAKSGGISFIYGSQSVEQQVEMVRRVKKFKAGFVLSDSNLRPEDTLKDVL 120 AVSDH+MA+ALA+ GGISFI+GSQS+E Q MVR+ K +KAGFV+S SNL P TLKD+L Sbjct: 61 AVSDHHMAVALARCGGISFIFGSQSIESQATMVRKAKGYKAGFVVSRSNLTPSHTLKDIL 120 Query: 121 ELKARSGHSTIAITDNGEPTGQLMGIVTSRDYRENRLPPDCRITEFMTPLSSLIYAREGI 180 ELK +GHST+AIT++G G+L+GIVT RDYR +R D +++ MTP S LIY + GI Sbjct: 121 ELKEATGHSTVAITEDGTAKGKLLGIVTGRDYRISRDSQDKLVSDIMTPFSKLIYGKSGI 180 Query: 181 TLTEANDMIWDHKLNCLPIVNSSGNLVHLVFRKDYDSHQEYPLELHDSNKQLIVGAGINS 240 TL+EAND+IW+HKLNCLPIV+ + NL LVFRKDYDS + PL L D+NK IVGAGIN+ Sbjct: 181 TLSEANDLIWEHKLNCLPIVDENQNLDFLVFRKDYDSRKNNPLSLLDANKSYIVGAGINT 240 Query: 241 RDYKERVPALVEAGADVLCIDSSDGYSEWQAETIHYIKETFGDNVKVGAGNVVDKEGFLY 300 +DYKERVPALVEAG D+L IDSSDG+SEWQ ET+ ++KE F NV +GAGNVVDKEGF Y Sbjct: 241 KDYKERVPALVEAGVDILVIDSSDGFSEWQRETVQFVKENF--NVPIGAGNVVDKEGFRY 298 Query: 301 LVEAGADFIKVGIGGGSICITREQKGIGRGQASSVIEVAAARQEYYEQTGIYVPICSDGG 360 LVE+GADFIKVGIGGGSICITREQKGIGRGQASS+IEVAAAR EY+++TGIYVP+CSDGG Sbjct: 299 LVESGADFIKVGIGGGSICITREQKGIGRGQASSLIEVAAARDEYFKETGIYVPLCSDGG 358 Query: 361 IVHDYHIVLALAMGADFVMLGRYFARFDESPGRKLLVGGNFVKEYWGEGSSRARNWQRYD 420 IVHDYH+ LALAMGADFVMLGRYFARFDESP +K+ +G NFVKEYWGEGS+RARNWQRYD Sbjct: 359 IVHDYHVTLALAMGADFVMLGRYFARFDESPTKKVKIGNNFVKEYWGEGSNRARNWQRYD 418 Query: 421 FGNADKESKLEFEEGVDSFIPYAGRLKDNLDLSISKIKSTMCNCGALTIPQLQQQAKITL 480 G +S L FEEGVDS++PYAG L++N+D ++SKIKSTMCNCG+L+I +LQQ+A+IT+ Sbjct: 419 TGG---KSSLVFEEGVDSYVPYAGSLRENIDRTLSKIKSTMCNCGSLSISELQQKARITV 475 Query: 481 VSSTTIYEGGAHDVMLKE 498 +S+T++ EGGAHDV+LKE Sbjct: 476 ISATSLVEGGAHDVILKE 493 >B0NHI2.1 B0NHI2_EUBSP Putative uncharacterized protein Length = 511 Score = 750 bits (1937), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/499 (67%), Positives = 428/499 (85%), Gaps = 3/499 (0%) Query: 1 MAYYYDQPSRTFSEFLLVPNLTTKECIPGNVDLRTPVTKFRKGETPALTMNLPVTSAVMQ 60 MA+YY++PSRTFSE+LL+P ++ EC+P V L TP+ KF KG+ P L+MN+P+ SA+MQ Sbjct: 15 MAFYYEEPSRTFSEYLLIPGYSSVECVPSKVSLETPLVKFEKGKEPELSMNIPMVSAIMQ 74 Query: 61 AVSDHNMAIALAKSGGISFIYGSQSVEQQVEMVRRVKKFKAGFVLSDSNLRPEDTLKDVL 120 +VSD +AIALA+ GG+SFIYGSQ +E Q EM+ +VK+++AGFV+SDSN+ E TL+DVL Sbjct: 75 SVSDDRLAIALAQEGGLSFIYGSQPIESQAEMIEKVKRYRAGFVVSDSNVSAEMTLQDVL 134 Query: 121 ELKARSGHSTIAITDNGEPTGQLMGIVTSRDYRENRLPPDCRITEFMTPLSSLIYAREGI 180 L ++GHSTIA+T++G P G+L+GIVT++DYR +R+ PD R+ +FMT L L+YA+E Sbjct: 135 RLTEQTGHSTIAVTEDGSPNGKLLGIVTNKDYRVSRMTPDTRVKDFMTKLDDLVYAQEET 194 Query: 181 TLTEANDMIWDHKLNCLPIVNSSGNLVHLVFRKDYDSHQEYPLELHDSNKQLIVGAGINS 240 TL EAND+IWDHK+NCLP+VN + LV+LVFRKDYD+H++ EL DS+K+ +VGAGIN+ Sbjct: 195 TLKEANDIIWDHKINCLPLVNKNQELVYLVFRKDYDTHKKNEYELIDSSKRYMVGAGINT 254 Query: 241 RDYKERVPALVEAGADVLCIDSSDGYSEWQAETIHYIKETFGDNVKVGAGNVVDKEGFLY 300 RDY+ERVPAL++AGAD+LCIDSS+G+SEWQ TI YI+ +GD VKVGAGNVVD EGF + Sbjct: 255 RDYEERVPALLKAGADILCIDSSEGFSEWQKLTIDYIRRNYGDRVKVGAGNVVDAEGFRF 314 Query: 301 LVEAGADFIKVGIGGGSICITREQKGIGRGQASSVIEVAAARQEYYEQTGIYVPICSDGG 360 L EAGADF+KVGIGGG+ICITREQKGIGRGQA+++IEVA AR YYE+TGIYVPICSDGG Sbjct: 315 LAEAGADFVKVGIGGGAICITREQKGIGRGQATALIEVAKARDAYYEETGIYVPICSDGG 374 Query: 361 IVHDYHIVLALAMGADFVMLGRYFARFDESPGRKLLVGGNFVKEYWGEGSSRARNWQRYD 420 IVHDYHI LALAMGADF+MLGRYFARFDESP +++ + G+++KEYWGEGS+RARNWQRYD Sbjct: 375 IVHDYHITLALAMGADFIMLGRYFARFDESPTKRVNINGSYMKEYWGEGSARARNWQRYD 434 Query: 421 FGNADKESKLEFEEGVDSFIPYAGRLKDNLDLSISKIKSTMCNCGALTIPQLQQQAKITL 480 G + KL FEEGVDSF+PYAG LKDN++L++SK++STMCNCGA+ IP+LQQ+AKITL Sbjct: 435 MGG---DKKLSFEEGVDSFVPYAGSLKDNVNLTLSKVRSTMCNCGAINIPELQQKAKITL 491 Query: 481 VSSTTIYEGGAHDVMLKEK 499 VSST+I EGGAHDVML++K Sbjct: 492 VSSTSIVEGGAHDVMLRDK 510 >Q92FC7.1 Q92FC7_LISIN Lin0179 protein Length = 502 Score = 748 bits (1932), Expect = 0.0, Method: Compositional matrix adjust. Identities = 332/498 (66%), Positives = 428/498 (85%), Gaps = 3/498 (0%) Query: 1 MAYYYDQPSRTFSEFLLVPNLTTKECIPGNVDLRTPVTKFRKGETPALTMNLPVTSAVMQ 60 MA+Y+++PSRTFSEFLLVP ++ EC+P NV L+TP+ KF+KGE A+TMN+P+ SA+MQ Sbjct: 1 MAFYFEEPSRTFSEFLLVPGYSSAECVPTNVSLKTPIVKFKKGEESAITMNIPLVSAIMQ 60 Query: 61 AVSDHNMAIALAKSGGISFIYGSQSVEQQVEMVRRVKKFKAGFVLSDSNLRPEDTLKDVL 120 AVSD NM IALAK GG+SF++GSQS+E + MV RVK KAGFV+SDSN+ P+ TL+D+L Sbjct: 61 AVSDDNMGIALAKEGGVSFVFGSQSIESEAAMVSRVKNHKAGFVISDSNISPDKTLQDIL 120 Query: 121 ELKARSGHSTIAITDNGEPTGQLMGIVTSRDYRENRLPPDCRITEFMTPLSSLIYAREGI 180 +LK ++GHST+A+T++G G+L+GIVTSRDYR R+ PD ++ +FMTP L+ A++ Sbjct: 121 DLKEKTGHSTVAVTEDGTAHGKLLGIVTSRDYRVTRMSPDEKVADFMTPFEKLVTAKKST 180 Query: 181 TLTEANDMIWDHKLNCLPIVNSSGNLVHLVFRKDYDSHQEYPLELHDSNKQLIVGAGINS 240 TL EAN++IWDHKLN LP+V+ + +LVH+VFRKDYDS++E LEL DS+K+ +VGAGIN+ Sbjct: 181 TLKEANNIIWDHKLNALPLVDDNEHLVHMVFRKDYDSNKENKLELLDSSKRYVVGAGINT 240 Query: 241 RDYKERVPALVEAGADVLCIDSSDGYSEWQAETIHYIKETFGDNVKVGAGNVVDKEGFLY 300 RDY+ERVPALVEAGAD+LCIDSS+GYSEWQ T+ Y++ +GD VKVGAGNVVD++GF Y Sbjct: 241 RDYEERVPALVEAGADILCIDSSEGYSEWQKRTLDYVRGKYGDTVKVGAGNVVDRDGFRY 300 Query: 301 LVEAGADFIKVGIGGGSICITREQKGIGRGQASSVIEVAAARQEYYEQTGIYVPICSDGG 360 L EAGADF+KVG+GGGSICITREQKGIGRGQA+++I+VA AR EY+E+TG+Y+PICSDGG Sbjct: 301 LAEAGADFVKVGVGGGSICITREQKGIGRGQATALIDVAKARDEYFEETGVYIPICSDGG 360 Query: 361 IVHDYHIVLALAMGADFVMLGRYFARFDESPGRKLLVGGNFVKEYWGEGSSRARNWQRYD 420 IV+DYH+ LALAMGADF+MLGRYF+RFDESP K+ + G ++KEYWGEG++RARNWQRYD Sbjct: 361 IVYDYHMTLALAMGADFIMLGRYFSRFDESPTNKVNLNGTYMKEYWGEGANRARNWQRYD 420 Query: 421 FGNADKESKLEFEEGVDSFIPYAGRLKDNLDLSISKIKSTMCNCGALTIPQLQQQAKITL 480 G + KL FEEGVDS++PYAG LKDN+ +S+SK++STMCNCGAL IP+LQQ+AKITL Sbjct: 421 LGG---DKKLSFEEGVDSYVPYAGSLKDNVAISLSKVRSTMCNCGALNIPELQQKAKITL 477 Query: 481 VSSTTIYEGGAHDVMLKE 498 VSST+I EGGAHDV++K+ Sbjct: 478 VSSTSIVEGGAHDVVVKD 495 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.135 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,021,410,115 Number of extensions: 131130234 Number of successful extensions: 332020 Number of sequences better than 1.0e-05: 2435 Number of HSP's gapped: 322064 Number of HSP's successfully gapped: 2470 Length of query: 504 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 364 Effective length of database: 1,741,754,103 Effective search space: 633998493492 Effective search space used: 633998493492 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 133 (55.8 bits)