BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0175.0021.p (474 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KAP2.1 B3KAP2_9BACI Peptidase M56 BlaR1 344 9e-93 B5Y638.1 B5Y638_COPPD Peptidase, M56 family protein 119 9e-25 B1B9E2.1 B1B9E2_CLOBO Putative membrane-associated metalloprotease 112 8e-23 B8FXI0.1 B8FXI0_DESHD Peptidase M56 BlaR1 110 4e-22 C5EGY9.1 C5EGY9_9FIRM Putative uncharacterized protein 101 2e-19 >B3KAP2.1 B3KAP2_9BACI Peptidase M56 BlaR1 Length = 500 Score = 344 bits (883), Expect = 9e-93, Method: Compositional matrix adjust. Identities = 200/360 (55%), Positives = 249/360 (69%), Gaps = 20/360 (5%) Query: 4 MNTILEILFSLTVAGSIVTASIHALRVLSTDHFSAKWRYRLTKMAVALYLLPIAFVIPWL 63 MNTILE+L +LTVAGS V A I LR++ + F KWRY + KMAV YLLP+ I W+ Sbjct: 1 MNTILELLLTLTVAGSAVVACILVLRIVFVNTFPTKWRYGIGKMAVVFYLLPVVLGIRWI 60 Query: 64 S---QFTASSMAADVHSL---------QPRSASFVSEPFLPAVTISANTAYVLLGIWAAG 111 S F+A++ V+ L P S + + EP +PA TIS N A L+ +WA G Sbjct: 61 SPLFTFSATATVPIVNELPSTVQHAMPGPYSGTGL-EPLIPAKTISVNVALPLIVLWAIG 119 Query: 112 GICFAAWQLYVYRRFIKELERTRTIVPENSETAIXXXXXXXXXXXXRNVRLAYSPLARSP 171 I FAAWQ+Y YRRF+K+LE +R VP +SE A +V LA+S + RSP Sbjct: 120 AIAFAAWQMYCYRRFLKKLEHSRVTVPISSEAAKQLSFIKEALGVKSSVGLAHSSIIRSP 179 Query: 172 FLAGLWKPSVYLPIESGAGLDMDMVLHHELIHLKRNDLWTKALTLGVSALHWFNPLAHTV 231 L GLWKP++Y PIE+ ++MDMV+ HELIHLKR DLW KA TLG SALHWFNPL H + Sbjct: 180 VLVGLWKPTIYFPIENT--VNMDMVIRHELIHLKRKDLWVKAFTLGASALHWFNPLVHIL 237 Query: 232 RKEIHIWSELSCDQEVVKEMSHAERKRXXXXTLLNVMAGARGLPEQFCASLSGDGKQLKR 291 RK++H+WSELSCD+EVVKEMS+AERKR T+L+VMAG+R LP QF ASLSGDGKQLKR Sbjct: 238 RKDLHVWSELSCDEEVVKEMSYAERKR-YGETILSVMAGSRNLPVQFIASLSGDGKQLKR 296 Query: 292 RLTHMLNVKKLQRQTIFLSVTAVLLIAGISTSAAAWASKVTPQV----AASTEEYPTEAA 347 RL MLNVKK +++T++L++TAV L+A ISTSAAAWAS TP+V A E PTEAA Sbjct: 297 RLMMMLNVKKQKKKTMYLTLTAVFLVAVISTSAAAWASSNTPKVIEKEAGHAEAQPTEAA 356 >B5Y638.1 B5Y638_COPPD Peptidase, M56 family protein Length = 816 Score = 119 bits (297), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 104/387 (26%), Positives = 177/387 (45%), Gaps = 24/387 (6%) Query: 3 MMNTILEILFSLTVAGSIVTASIHALRVLSTDHFSAKWRYRLTKMAVALYLLPIAFVIPW 62 M+ T+ + + ++++ SIV + L L +SAKWRY + + L+P + I Sbjct: 3 MLETLFQKVLQVSMSTSIVIGVLLLLLPLINRSYSAKWRYLVWLIIAVRLLIPFSPSIAG 62 Query: 63 LSQFTASSMAADVHSLQPRSASF-VSE-----PFLPAVTISANTAYV--------LLGIW 108 + T S++ +V P A+ +SE P P ++ N++ V L IW Sbjct: 63 EAPVTIPSVSQNVQIPIPLPANTNLSEQTNIIPTQPTPVVTPNSSAVRTITLADLLPVIW 122 Query: 109 AAGGICFAAWQLYVYRRFIKELERTRTIVPENSETAIXXXXXXXXXXXXRNVRLAYSPLA 168 G I F + Y F K R IV E+ +T N+ L S Sbjct: 123 LIGAILFMTYYFAGYIVFRKSAMRFSEIV-EDEQTLATFSQMKQEMGTKGNIELIRSKKV 181 Query: 169 RSPFLAGLWKPSVYLPIESGAGLDMDMVLHHELIHLKRNDLWTKALTLGVSALHWFNPLA 228 +SP + G KP LP + D+++++ HELIH K D+W K + + +A+HWFNPL Sbjct: 182 QSPMITGFVKPIFLLPYVEYSEADLELIMKHELIHYKHKDIWNKLVMVVANAVHWFNPLV 241 Query: 229 HTVRKEIHIWSELSCDQEVVKEMSHAERKRXXXXTLLNVMAGARGLPEQFCASLSGDGKQ 288 + +R + E++CD E+V E + E ++ T+L+ + R F G K Sbjct: 242 YVMRYRSNADIEMACDSELV-EGTGTEFRKQYSETILSAIHKGRERETVFSTYFYGGVKT 300 Query: 289 LKRRLTHMLN--VKKLQRQTIFLSVTAVLLIAGISTSAAAWASKVTPQVAASTEEYPTEA 346 +K RL ++ + K+ + L V AV++I + + A+++T + A E Sbjct: 301 MKERLGNIFDGGGKRGGIVALCLVVAAVIVIGALVACGGSTAAELTAEEKAQITELLDNF 360 Query: 347 AKPAASAGNITSGTVDPESVPA-QVQE 372 + N+T +DPE+V A Q++E Sbjct: 361 GRELT---NVT--IIDPENVVAEQIKE 382 >B1B9E2.1 B1B9E2_CLOBO Putative membrane-associated metalloprotease Length = 376 Score = 112 bits (280), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 88/359 (24%), Positives = 164/359 (45%), Gaps = 16/359 (4%) Query: 27 ALRVLSTDHFSAKWRYRLTKMAVALYLLPIAFVIP-WLSQFTASSMAADVHSLQPRSASF 85 LR + H++ + Y + + + ++P F IP +LS T D+ S++ Sbjct: 24 VLRKCLSKHYTQNFIYYMWLLIIVKLIIP--FKIPIYLS--TQIYNVFDITSVEKIKEHI 79 Query: 86 VSEPFLPAVTISANTAYVLL--GIWAAGGICFAAWQLYVYRRFIKELERTRTIVPENSET 143 + + + + N + +++ IW G I ++ +Y Y +FIK ++ V + E Sbjct: 80 LLQQ--RNINLQGNISIIMIVTYIWVMGVILAGSYYIYSYLKFIKNIKLFSYEVTD-EEV 136 Query: 144 AIXXXXXXXXXXXXRNVRLAYSPLARSPFLAGLWKPSVYLPIESGAGLDMDMVLHHELIH 203 + + L Y SPF G+ PSV LP S + ++ ++L HEL+H Sbjct: 137 VNIYNGLKCKLKINKKIPLKYYNNITSPFGVGILNPSVVLPKVSYSPTELKIILTHELMH 196 Query: 204 LKRNDLWTKALTLGVSALHWFNPLAHTVRKEIHIWSELSCDQEVVKEMSHAERKRXXXXT 263 K++DL K+L + V LHWFNPL + + I++ EL+CD+ +VK + ERK Sbjct: 197 FKKHDLLYKSLLVFVKILHWFNPLVYAMCNIINLDCELACDESLVKGLGIEERKLYAMTL 256 Query: 264 LLNVMAGARGLPEQFCASLSGDGKQLKRRLTHMLNVKKLQRQTIFLSVTAVLLIAGISTS 323 + ++ + + + + LKRR+ +ML++K +R I ++ AV++ + + S Sbjct: 257 INSIRVRKKSTFKNDIVTSFNNKSILKRRIGNMLDLKNKKRGIIVGTICAVIMTSSL-FS 315 Query: 324 AAAWASKVTPQVAASTEEYPT-----EAAKPAASAGNITSGTVDPESVPAQVQEGSVAR 377 A KVT + + ++ + T + S N S + + EGS + Sbjct: 316 MNVCAEKVTERASVNSSKAITNPSIKKHTSEVKSGSNEDSKILYKYKTNCNMTEGSTFK 374 >B8FXI0.1 B8FXI0_DESHD Peptidase M56 BlaR1 Length = 465 Score = 110 bits (274), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 86/354 (24%), Positives = 158/354 (44%), Gaps = 24/354 (6%) Query: 4 MNTILEILFSLTVAGSIVTASIHALRVLSTDHFSAKWRYRLTKMAVALYLLPIAFVIPWL 63 M + + L + ++ S + A+ L +SAK RY A ++ I +IP+ Sbjct: 1 MQSFIVTLLTCSITMSAIALFYMAVTPLLAKRYSAKGRYY------AWLIIVIGLIIPFR 54 Query: 64 SQFTASSMA-----ADVHSLQPRSASFVSEPFLPAVTISANTAYVLL-------GIWAAG 111 QF + ++Q + + ++ P A++ S++ +++LL +W AG Sbjct: 55 PQFDNPFVKIIPTETATPTIQIGNRTQIAGPVESALS-SSDVSHILLSWWQIAAAVWLAG 113 Query: 112 GICFAAWQLYVYRRFIKELER-TRTIVPENSETAIXXXXXXXXXXXXRNVRLAYSPLARS 170 I F + + RF+K +R TI E + N+ S + Sbjct: 114 MIAFLVYHTVKHYRFMKMTKRWCETITDEQILSLFQNLKAELGISKQINLDQCLS--IGT 171 Query: 171 PFLAGLWKPSVYLPIESGAGLDMDMVLHHELIHLKRNDLWTKALTLGVSALHWFNPLAHT 230 P L G ++P + LP ++ ++L+HEL+H KR DLW + L L A+HWFNPL + Sbjct: 172 PMLIGFFQPKILLPTTKFPKNELRLILNHELVHYKRKDLWYRCLVLSAKAIHWFNPLVYL 231 Query: 231 VRKEIHIWSELSCDQEVVKEMSHAERKRXXXXTLLNVMAGARGLPEQFCASLSGDGKQLK 290 + K I E+SCD EVV + A+ ++ ++ V+ + S G K +K Sbjct: 232 MAKAIDAVCEMSCDAEVVHSID-ADMRQQYSEAIIGVVQYQSKVKTALSTSFYGGKKGMK 290 Query: 291 RRLTHMLNVKKLQRQTIFLSVTAVLLIAGISTSAAAWASKVTPQVAASTEEYPT 344 R++ +++ K +R + ++ +LL + A + V + ++E PT Sbjct: 291 ERISSIMDAGK-KRVGVIIACAILLLTLSTGVAFAVSSDAVEMALENESQELPT 343 >C5EGY9.1 C5EGY9_9FIRM Putative uncharacterized protein Length = 465 Score = 101 bits (251), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 70/228 (30%), Positives = 121/228 (53%), Gaps = 10/228 (4%) Query: 119 QLYVYRRFIKELERTRTIVPENSETAIXX--XXXXXXXXXXRNVRLAYSPLARSPFLAGL 176 ++ +Y+ FIK + R E S+TAI R V + + L SP L G Sbjct: 5 KITIYQGFIKYIRAGRA---EVSDTAILDRLALIGEQAGVKRPVEIYTNSLISSPLLLGF 61 Query: 177 WKPSVYLPIESGAGLDMDMVLHHELIHLKRNDLWTKALTLGVSALHWFNPLAHTVRKEIH 236 ++P + LP + A D + + HEL H KR D++ K L V LHWFNP+ + + +E+ Sbjct: 62 FRPCIVLPSTNLAPADFEHTILHELTHYKRRDMFYKWLVQLVICLHWFNPIVYAMGREVG 121 Query: 237 IWSELSCDQEVVKEMSHAERKRXXXXTLLNVMAGARGLPEQFCASLS-GDGKQ-LKRRLT 294 EL+CD+ V+K + + +R TLLN + GA G + F AS++ + K+ LK RL Sbjct: 122 RACELACDEAVIKALD-PQGRRAYGDTLLNAI-GAGGGYKDFLASVTLNESKELLKERLD 179 Query: 295 HMLNVKKLQRQTIFLSVTAVLLIAGISTSAAAWA-SKVTPQVAASTEE 341 ++ K+ + + +++ LL+ +T+ A+A +++ P+ +TE+ Sbjct: 180 AIMKYKRTSKIMLTVTLAITLLMVTGATAIGAYAKTQMPPEPIGNTEK 227 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.130 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,373,196,076 Number of extensions: 87209418 Number of successful extensions: 268190 Number of sequences better than 1.0e-05: 288 Number of HSP's gapped: 268097 Number of HSP's successfully gapped: 288 Length of query: 474 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 334 Effective length of database: 1,741,754,103 Effective search space: 581745870402 Effective search space used: 581745870402 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 133 (55.8 bits)