BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0175.0018.p (204 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KAF7.1 B3KAF7_9BACI Regulatory protein TetR 130 5e-29 Q5WKD2.1 Q5WKD2_BACSK TetR family transcriptional regulator 128 4e-28 C0ZET2.1 C0ZET2_BREBN Probable transcriptional regulator 120 7e-26 A6M043.1 A6M043_CLOB8 Transcriptional regulator, TetR family 114 6e-24 B3KHM9.1 B3KHM9_9BACI Regulatory protein TetR 96 2e-18 >B3KAF7.1 B3KAF7_9BACI Regulatory protein TetR Length = 196 Score = 130 bits (328), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 69/188 (36%), Positives = 101/188 (53%), Gaps = 4/188 (2%) Query: 9 LPPNPNDPRVIRTRQLILDAFVRQLNVMDFNSITVGDITKAATINRATFYAHFQDKYALF 68 + N DPRVIRTR+L+ DAF + DF SITV DI + AT+NRATFYAHF DK+ + Sbjct: 3 IKKNEADPRVIRTRRLLQDAFASLIQDKDFESITVKDIAERATVNRATFYAHFVDKFEIL 62 Query: 69 EAFLLDAFTNLVLNKIDTEGPLTEKTLQELIVALCNYH-ETSHRCFKRYDSVALLLEENI 127 EA L+++F ++ +I L E+T+Q + + +C++H + S C +RY S+ + E I Sbjct: 63 EARLMESFMTIINRRISGHEVLNEETIQSIFLGVCDFHKDLSTMCKRRYTSLGAVFEIQI 122 Query: 128 KVHLEKLVLQLIXXXXXXXX---XXXXXXXXXXXXXXXYGVTYRWNLEGRSESASELAER 184 K ++ ++L I YG Y WN EGR SA ++ Sbjct: 123 KEKIQTILLSFIDKDKMLSSPNAQFLINTATNMLSWGMYGAAYAWNNEGRLISAESFVKQ 182 Query: 185 VMPLITGG 192 MPL+ G Sbjct: 183 TMPLVMNG 190 >Q5WKD2.1 Q5WKD2_BACSK TetR family transcriptional regulator Length = 214 Score = 128 bits (321), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 68/187 (36%), Positives = 100/187 (53%), Gaps = 4/187 (2%) Query: 10 PPNPNDPRVIRTRQLILDAFVRQLNVMDFNSITVGDITKAATINRATFYAHFQDKYALFE 69 N DPRVIRTR+L+ DAF + DF SITV DI + AT+NRATFYAHF DK+ + E Sbjct: 22 KKNEADPRVIRTRRLLQDAFASLIQEKDFESITVKDIAERATVNRATFYAHFIDKFEILE 81 Query: 70 AFLLDAFTNLVLNKIDTEGPLTEKTLQELIVALCNYH-ETSHRCFKRYDSVALLLEENIK 128 A L+++F ++ +I L E+T+Q + + +C++H + S C +R S+ + E IK Sbjct: 82 ARLMESFMTIINRRICGHEVLNEETIQSIFLGVCDFHKDLSAMCKRRNASLGAVFETQIK 141 Query: 129 VHLEKLVLQLIXXXXXXXXXXXX---XXXXXXXXXXXYGVTYRWNLEGRSESASELAERV 185 ++ ++L I YG+ Y WN EGR SA ++ Sbjct: 142 EKIQTILLSFIDKDKMLSSSNAQFLINTASIMLSWGMYGLAYVWNKEGRQISAESFVKQS 201 Query: 186 MPLITGG 192 MPL+ G Sbjct: 202 MPLVMNG 208 >C0ZET2.1 C0ZET2_BREBN Probable transcriptional regulator Length = 196 Score = 120 bits (301), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 67/185 (36%), Positives = 98/185 (52%), Gaps = 4/185 (2%) Query: 12 NPNDPRVIRTRQLILDAFVRQLNVMDFNSITVGDITKAATINRATFYAHFQDKYALFEAF 71 N DPRVIRTR+L+ DAF + DF SITV DI + AT+NRATFYAHF DK+ + EA Sbjct: 6 NEADPRVIRTRRLLQDAFASLIQEKDFESITVRDIAERATVNRATFYAHFVDKFEILEAR 65 Query: 72 LLDAFTNLVLNKIDTEGPLTEKTLQELIVALCNYH-ETSHRCFKRYDSVALLLEENIKVH 130 L+++F ++ ++I L E+T+Q + + +C +H S C +R S+ + E IK Sbjct: 66 LMESFMTIMNHRISGHEGLNEETIQSIFLGVCEFHMGLSTMCKRRNTSLVPVFEIRIKEK 125 Query: 131 LEKLVLQLIXXXXXXXX---XXXXXXXXXXXXXXXYGVTYRWNLEGRSESASELAERVMP 187 ++ ++L I YG Y WN EGR SA ++ +P Sbjct: 126 IQTILLSFIDKDKMLSTPNQQFLINTASVMLSWGMYGAAYVWNNEGRLISAESFVKQSLP 185 Query: 188 LITGG 192 L+ G Sbjct: 186 LVMNG 190 >A6M043.1 A6M043_CLOB8 Transcriptional regulator, TetR family Length = 198 Score = 114 bits (284), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 62/184 (33%), Positives = 102/184 (55%), Gaps = 6/184 (3%) Query: 14 NDPRVIRTRQLILDAFVRQLNVMDFNSITVGDITKAATINRATFYAHFQDKYALFEAFLL 73 ND R+ ++R+LI DAF+ N F +ITV DI++ A +NRATFYAHF+DKY L ++F+ Sbjct: 8 NDKRITKSRKLIQDAFLSLANKRPFENITVKDISERANVNRATFYAHFKDKYDLLDSFIS 67 Query: 74 DAFTNLVLNKIDTEGPLTEKTLQELIVALCNYHETSHRCFKR-YDSVALLLEENIKVHLE 132 D F +V ++I + L EKTL++LI +C+YH+T + R Y S +L++ +++ L+ Sbjct: 68 DEFMTIVSSRISPDAKLNEKTLRDLIFIMCDYHKTVGTSYIRLYKSANMLIDMRVQLKLQ 127 Query: 133 KLVLQLIXXXXXXXXXXXXXXXXXXXXXXX--YGVTYRWNLEGRSESA---SELAERVMP 187 +V ++ Y T RW+ +G + A S LA+ ++ Sbjct: 128 DIVQNMLNNTRACSKNEDEKLELITVMMSSGIYCATKRWHSKGNLKDASAVSALADEILS 187 Query: 188 LITG 191 +T Sbjct: 188 FMTS 191 >B3KHM9.1 B3KHM9_9BACI Regulatory protein TetR Length = 201 Score = 95.9 bits (237), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 60/197 (30%), Positives = 95/197 (48%), Gaps = 6/197 (3%) Query: 12 NPNDPRVIRTRQLILDAFVRQLNVMDFNSITVGDITKAATINRATFYAHFQDKYALFEAF 71 NPNDPR RTR+ I AF L MDF ++++ DI A +NRATFY H+QDKY L E Sbjct: 5 NPNDPRAKRTRKYIQKAFTDLLVEMDFENLSIQDIMDRAELNRATFYNHYQDKYELLELT 64 Query: 72 LLDAFTNLVLNKI--DTEGPLTEKTLQELIVALCNYHETSHRCFKRYDSVALLLEENIKV 129 + AFT ++ +I T+ TE L+ L++A+C + + + +++ +E+N K Sbjct: 65 MTSAFTEILSTQIPPGTQMQGTE-LLRNLMLAVCEWQIETTKLLNARRTLSRAMEDNAKQ 123 Query: 130 HLEKLVLQLIXXXXX--XXXXXXXXXXXXXXXXXXYGVTYRWNLEGRSESASELAERVMP 187 L +++ + YGV +W+ + + E A + E V+P Sbjct: 124 QLYNVIISCMAHVKDLPAEEQRRMEWVATMISWSIYGVVVKWS-QRQEEPAEQFIEHVLP 182 Query: 188 LITGGFRMFKPQVSYSE 204 + R Q S E Sbjct: 183 FLMSNLRTLNLQGSQEE 199 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.323 0.138 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 966,610,787 Number of extensions: 29936316 Number of successful extensions: 79943 Number of sequences better than 1.0e-05: 246 Number of HSP's gapped: 80054 Number of HSP's successfully gapped: 246 Length of query: 204 Length of database: 3,060,696,203 Length adjustment: 129 Effective length of query: 75 Effective length of database: 1,845,385,268 Effective search space: 138403895100 Effective search space used: 138403895100 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 128 (53.9 bits)