BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0173.0004.p (443 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K8P9.1 B3K8P9_9BACI Adenylosuccinate synthetase EC=6.3.4.4 817 0.0 Q65CR5.1 PURA_BACLD Adenylosuccinate synthetase EC=6.3.4.4 651 0.0 B7GMU2.1 B7GMU2_ANOFW Adenylosuccinate synthetase EC=6.3.4.4 649 0.0 C5D9W9.1 C5D9W9_9BACI Adenylosuccinate synthetase EC=6.3.4.4 647 0.0 A7ZAP4.1 PURA_BACA2 Adenylosuccinate synthetase EC=6.3.4.4 647 0.0 >B3K8P9.1 B3K8P9_9BACI Adenylosuccinate synthetase EC=6.3.4.4 Length = 429 Score = 817 bits (2110), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/427 (91%), Positives = 411/427 (96%) Query: 16 MSTVVVVGTQWGDEGKGKITDFLAESADVVARYQGGNNAGHTILIDGKKFKLSLIPSGVF 75 MSTVVVVGTQWGDEGKGKITD+LAESADVVARYQGGNNAGHTILIDGKKFKLSLIPSGVF Sbjct: 1 MSTVVVVGTQWGDEGKGKITDYLAESADVVARYQGGNNAGHTILIDGKKFKLSLIPSGVF 60 Query: 76 YKEKTCVIGNGMVINPEALIQEINYIHENGFDTKNLVISDRAHVIMPYHMLLDALEEDRK 135 YK+KTCVIGNGMV+NP ALI+EINYIH+NGF T NLVISDRAHVIMPYHM+LDALEEDRK Sbjct: 61 YKDKTCVIGNGMVVNPAALIEEINYIHDNGFSTDNLVISDRAHVIMPYHMVLDALEEDRK 120 Query: 136 GPNKIGTTRKGIGPAYMDKAARNGIRISDLMDAEEFELRLRHLMKEKNQVITQVYGAEAL 195 GPNKIGTTRKGIGP YMDKAARNGIRI+DLMDAEEFEL+LRHL+KEKNQVITQVYG EAL Sbjct: 121 GPNKIGTTRKGIGPCYMDKAARNGIRIADLMDAEEFELKLRHLVKEKNQVITQVYGGEAL 180 Query: 196 DVEEVLTKYLEYAEVLRSYVTDTSVVLNDAIDANSKVLFEGAQGVMLDIDQGTYPFVTSS 255 DVEE+LT+YLEYAEV+R YV DTSVVLNDAID N KVLFEGAQGVMLDIDQGTYPFVTSS Sbjct: 181 DVEEILTQYLEYAEVIRKYVRDTSVVLNDAIDENQKVLFEGAQGVMLDIDQGTYPFVTSS 240 Query: 256 NPSAGGVCIGSGVGPSKIQQVIGVAKSYTTRVGDGPFPTELNDSIGDYIRETGHEYGTIT 315 NPSAGGVCIGSGVGPSKIQQVIGVAKSYTTRVGDGPFPTEL++ IG+YIRE GHEYGT+T Sbjct: 241 NPSAGGVCIGSGVGPSKIQQVIGVAKSYTTRVGDGPFPTELDNEIGEYIREKGHEYGTVT 300 Query: 316 GRARRVGWFDSVVVRHARRVSGITGLSLNSLDVLSGLETVKICTGYKYRGEVITHYPASL 375 GRARRVGWFDSVVVRHARRVSGITGLSLNSLDVLSGLETVKICT YK+RGE ITHYPASL Sbjct: 301 GRARRVGWFDSVVVRHARRVSGITGLSLNSLDVLSGLETVKICTAYKFRGEEITHYPASL 360 Query: 376 KMLAECEAVYEELPGWSEDITTAKTLADLPVNTRKYVERVSELTGIPISIFSVGRNREQT 435 KMLAECEA+YEELPGWSEDIT AKTL DLP NTR+YVERVSELTGIPI+IFSVGRNREQT Sbjct: 361 KMLAECEAIYEELPGWSEDITGAKTLEDLPENTRRYVERVSELTGIPIAIFSVGRNREQT 420 Query: 436 NQVLPIY 442 NQVLPIY Sbjct: 421 NQVLPIY 427 >Q65CR5.1 PURA_BACLD Adenylosuccinate synthetase EC=6.3.4.4 Length = 430 Score = 651 bits (1680), Expect = 0.0, Method: Compositional matrix adjust. Identities = 304/427 (71%), Positives = 366/427 (85%) Query: 16 MSTVVVVGTQWGDEGKGKITDFLAESADVVARYQGGNNAGHTILIDGKKFKLSLIPSGVF 75 MS+VVVVGTQWGDEGKGKITDFL+E+A+V+ARYQGGNNAGHTI +G +KL LIPSG+F Sbjct: 1 MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGNNAGHTIKFNGVTYKLHLIPSGIF 60 Query: 76 YKEKTCVIGNGMVINPEALIQEINYIHENGFDTKNLVISDRAHVIMPYHMLLDALEEDRK 135 YK+KTCVIGNGMV++P+AL+ E+ Y+HE T NL IS+RAHVI+PYH+ LDA+EE+RK Sbjct: 61 YKDKTCVIGNGMVVDPKALVTELAYLHERNVSTDNLRISNRAHVILPYHLKLDAVEEERK 120 Query: 136 GPNKIGTTRKGIGPAYMDKAARNGIRISDLMDAEEFELRLRHLMKEKNQVITQVYGAEAL 195 G NKIGTT+KGIGPAYMDKAAR GIRI+DL+D + FE +L ++EKN+++ ++Y AE Sbjct: 121 GANKIGTTKKGIGPAYMDKAARVGIRIADLLDRDVFEEKLARNLEEKNRLLEKMYDAEGF 180 Query: 196 DVEEVLTKYLEYAEVLRSYVTDTSVVLNDAIDANSKVLFEGAQGVMLDIDQGTYPFVTSS 255 +E++L +Y EY + ++ YV DTSVVLNDA+D +VLFEGAQGVMLDIDQGTYPFVTSS Sbjct: 181 KIEDILDEYYEYGQQIKQYVCDTSVVLNDALDDGRRVLFEGAQGVMLDIDQGTYPFVTSS 240 Query: 256 NPSAGGVCIGSGVGPSKIQQVIGVAKSYTTRVGDGPFPTELNDSIGDYIRETGHEYGTIT 315 NP AGGV IGSGVGP+KIQ V+GV+K+YTTRVGDGPFPTELN+ IGD IRE G EYGT T Sbjct: 241 NPVAGGVTIGSGVGPTKIQHVVGVSKAYTTRVGDGPFPTELNNEIGDQIREVGREYGTTT 300 Query: 316 GRARRVGWFDSVVVRHARRVSGITGLSLNSLDVLSGLETVKICTGYKYRGEVITHYPASL 375 GR RRVGWFDSVVVRHARRVSGIT LSLNS+DVL+G+ET+KIC YKYRGE++ +PASL Sbjct: 301 GRPRRVGWFDSVVVRHARRVSGITDLSLNSIDVLTGIETLKICVAYKYRGEILEEFPASL 360 Query: 376 KMLAECEAVYEELPGWSEDITTAKTLADLPVNTRKYVERVSELTGIPISIFSVGRNREQT 435 K LAECE VYEE+PGW+EDIT AK+L+DLP N R Y+ERVS+LTGIP+SIFSVG +R QT Sbjct: 361 KALAECEPVYEEMPGWTEDITGAKSLSDLPENARHYLERVSQLTGIPLSIFSVGPDRSQT 420 Query: 436 NQVLPIY 442 N V +Y Sbjct: 421 NVVRSVY 427 >B7GMU2.1 B7GMU2_ANOFW Adenylosuccinate synthetase EC=6.3.4.4 Length = 439 Score = 649 bits (1673), Expect = 0.0, Method: Compositional matrix adjust. Identities = 302/429 (70%), Positives = 364/429 (84%) Query: 14 MNMSTVVVVGTQWGDEGKGKITDFLAESADVVARYQGGNNAGHTILIDGKKFKLSLIPSG 73 + MS+VVVVGTQWGDEGKGKITDFL++ A+V+ARYQGGNNAGHTI+ +G+K+KL LIPSG Sbjct: 10 LAMSSVVVVGTQWGDEGKGKITDFLSQHAEVIARYQGGNNAGHTIVFNGEKYKLHLIPSG 69 Query: 74 VFYKEKTCVIGNGMVINPEALIQEINYIHENGFDTKNLVISDRAHVIMPYHMLLDALEED 133 +FYK+K CVIGNGMV++P+AL+QE+ Y+HE G T NL IS+RAHVI+PYH+ LD +EE+ Sbjct: 70 IFYKDKICVIGNGMVVDPKALVQELAYLHERGVSTDNLRISNRAHVILPYHLKLDEVEEE 129 Query: 134 RKGPNKIGTTRKGIGPAYMDKAARNGIRISDLMDAEEFELRLRHLMKEKNQVITQVYGAE 193 RKG NKIGTT+KGIGPAYMDKAAR GIRI+DL+D E FE +L + EKN + +VYG E Sbjct: 130 RKGANKIGTTKKGIGPAYMDKAARVGIRIADLLDREVFEEKLARNLAEKNVLFEKVYGVE 189 Query: 194 ALDVEEVLTKYLEYAEVLRSYVTDTSVVLNDAIDANSKVLFEGAQGVMLDIDQGTYPFVT 253 +E +L +Y EY + + YV DTSVVLNDA+D +VLFEGAQGVMLDIDQGTYPFVT Sbjct: 190 GFQLEHILDEYYEYGQQIAKYVCDTSVVLNDALDEGRRVLFEGAQGVMLDIDQGTYPFVT 249 Query: 254 SSNPSAGGVCIGSGVGPSKIQQVIGVAKSYTTRVGDGPFPTELNDSIGDYIRETGHEYGT 313 SSNP AGGV IG+GVGP+KI+ V+GVAK+YTTRVGDGPFPTELN+ IGD IRE G EYGT Sbjct: 250 SSNPVAGGVTIGAGVGPTKIKHVVGVAKAYTTRVGDGPFPTELNNEIGDRIREVGREYGT 309 Query: 314 ITGRARRVGWFDSVVVRHARRVSGITGLSLNSLDVLSGLETVKICTGYKYRGEVITHYPA 373 TGR RRVGWFDSVVVRHARRVSGIT LSLNS+DVL+G+ET+KIC Y+Y+G++I +PA Sbjct: 310 TTGRPRRVGWFDSVVVRHARRVSGITDLSLNSIDVLTGIETLKICVAYRYKGQIIEEFPA 369 Query: 374 SLKMLAECEAVYEELPGWSEDITTAKTLADLPVNTRKYVERVSELTGIPISIFSVGRNRE 433 SLK+LAECE VYEELPGW+EDIT K+L +LP N R+YVER+S+LTGIP+SIFSVG +R Sbjct: 370 SLKVLAECEPVYEELPGWTEDITGVKSLDELPANARRYVERISQLTGIPLSIFSVGPDRS 429 Query: 434 QTNQVLPIY 442 QTN V +Y Sbjct: 430 QTNVVRNVY 438 >C5D9W9.1 C5D9W9_9BACI Adenylosuccinate synthetase EC=6.3.4.4 Length = 428 Score = 647 bits (1670), Expect = 0.0, Method: Compositional matrix adjust. Identities = 303/427 (70%), Positives = 364/427 (85%) Query: 16 MSTVVVVGTQWGDEGKGKITDFLAESADVVARYQGGNNAGHTILIDGKKFKLSLIPSGVF 75 MS+VVVVGTQWGDEGKGKITDFL+E+A+V+ARYQGGNNAGHTI+ +G+K+KL LIPSG+F Sbjct: 1 MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGNNAGHTIVFNGEKYKLHLIPSGIF 60 Query: 76 YKEKTCVIGNGMVINPEALIQEINYIHENGFDTKNLVISDRAHVIMPYHMLLDALEEDRK 135 YK+K CVIGNGMV++P+AL+ E+ Y+H+ G T NL IS+RAHVI+PYH+ LD LEE+RK Sbjct: 61 YKDKICVIGNGMVVDPKALVAELKYLHDRGISTDNLRISNRAHVILPYHLKLDELEEERK 120 Query: 136 GPNKIGTTRKGIGPAYMDKAARNGIRISDLMDAEEFELRLRHLMKEKNQVITQVYGAEAL 195 G NKIGTT+KGIGPAYMDKAAR GIRI DL+D E FE +L ++EKN + +VYG E Sbjct: 121 GANKIGTTKKGIGPAYMDKAARVGIRIVDLLDREVFEEKLARNLQEKNVLFEKVYGVEGF 180 Query: 196 DVEEVLTKYLEYAEVLRSYVTDTSVVLNDAIDANSKVLFEGAQGVMLDIDQGTYPFVTSS 255 +E++L +Y EY + + YV DTSVVLN+A+D +VLFEGAQGVMLDIDQGTYPFVTSS Sbjct: 181 KLEDILDEYYEYGQQIAKYVCDTSVVLNNALDEGRRVLFEGAQGVMLDIDQGTYPFVTSS 240 Query: 256 NPSAGGVCIGSGVGPSKIQQVIGVAKSYTTRVGDGPFPTELNDSIGDYIRETGHEYGTIT 315 NP AGGV IG+GVGP+KI+ V+GVAK+YTTRVGDGPFPTEL+D IGD IRE G EYGT T Sbjct: 241 NPVAGGVTIGAGVGPTKIKHVVGVAKAYTTRVGDGPFPTELHDEIGDRIREVGREYGTTT 300 Query: 316 GRARRVGWFDSVVVRHARRVSGITGLSLNSLDVLSGLETVKICTGYKYRGEVITHYPASL 375 GR RRVGWFDSVVVRHARRVSGIT LSLNS+DVL+G+ET+KIC Y+Y+G+VI +PASL Sbjct: 301 GRPRRVGWFDSVVVRHARRVSGITDLSLNSIDVLTGIETLKICVAYRYKGKVIEEFPASL 360 Query: 376 KMLAECEAVYEELPGWSEDITTAKTLADLPVNTRKYVERVSELTGIPISIFSVGRNREQT 435 K+LAECE +YEELPGWSEDIT K+L +LPVN R YVER+S+LTGIP+SIFSVG +R QT Sbjct: 361 KVLAECEPIYEELPGWSEDITGVKSLDELPVNARHYVERISQLTGIPLSIFSVGPDRSQT 420 Query: 436 NQVLPIY 442 N V +Y Sbjct: 421 NVVRSVY 427 >A7ZAP4.1 PURA_BACA2 Adenylosuccinate synthetase EC=6.3.4.4 Length = 430 Score = 647 bits (1668), Expect = 0.0, Method: Compositional matrix adjust. Identities = 303/427 (70%), Positives = 361/427 (84%) Query: 16 MSTVVVVGTQWGDEGKGKITDFLAESADVVARYQGGNNAGHTILIDGKKFKLSLIPSGVF 75 MS+VVVVGTQWGDEGKGKITDFL+E+A+V+ARYQGGNNAGHTI DG +KL LIPSG+F Sbjct: 1 MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGNNAGHTIKFDGVTYKLHLIPSGIF 60 Query: 76 YKEKTCVIGNGMVINPEALIQEINYIHENGFDTKNLVISDRAHVIMPYHMLLDALEEDRK 135 YKEK CVIGNGMV++P+ALI E+ Y+HE T NL IS+RAHVI+PYH+ LD +EE+RK Sbjct: 61 YKEKACVIGNGMVVDPKALITELAYLHERNVSTDNLRISNRAHVILPYHLKLDEVEEERK 120 Query: 136 GPNKIGTTRKGIGPAYMDKAARNGIRISDLMDAEEFELRLRHLMKEKNQVITQVYGAEAL 195 G NKIGTT+KGIGPAYMDKAAR GIRI+DL+D + F +L ++EKN+++ ++Y E Sbjct: 121 GANKIGTTKKGIGPAYMDKAARIGIRIADLLDRDVFAEKLERNLEEKNRLLEKMYETEGF 180 Query: 196 DVEEVLTKYLEYAEVLRSYVTDTSVVLNDAIDANSKVLFEGAQGVMLDIDQGTYPFVTSS 255 +E++L +Y EY + ++ YV DTSVVLNDA+D +VLFEGAQGVMLDIDQGTYPFVTSS Sbjct: 181 KIEDILDEYYEYGQQIKKYVCDTSVVLNDALDEGRRVLFEGAQGVMLDIDQGTYPFVTSS 240 Query: 256 NPSAGGVCIGSGVGPSKIQQVIGVAKSYTTRVGDGPFPTELNDSIGDYIRETGHEYGTIT 315 NP AGGV IGSGVGP+KIQ V+GV+K+YTTRVGDGPFPTEL D IGD IRE G EYGT T Sbjct: 241 NPVAGGVTIGSGVGPTKIQHVVGVSKAYTTRVGDGPFPTELKDEIGDQIREVGREYGTTT 300 Query: 316 GRARRVGWFDSVVVRHARRVSGITGLSLNSLDVLSGLETVKICTGYKYRGEVITHYPASL 375 GR RRVGWFDSVVVRHARRVSGIT LSLNS+DVL+G+ET+KIC Y+Y+GEVI +PASL Sbjct: 301 GRPRRVGWFDSVVVRHARRVSGITDLSLNSIDVLTGIETLKICVAYRYKGEVIEEFPASL 360 Query: 376 KMLAECEAVYEELPGWSEDITTAKTLADLPVNTRKYVERVSELTGIPISIFSVGRNREQT 435 K LAECE VYEE+PGW+EDIT AKTL+DLP N R Y+ERVS+LTGIP+SIFSVG +R QT Sbjct: 361 KALAECEPVYEEMPGWTEDITGAKTLSDLPENARHYLERVSQLTGIPLSIFSVGPDRSQT 420 Query: 436 NQVLPIY 442 N + +Y Sbjct: 421 NVIRSVY 427 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.316 0.135 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,651,217,980 Number of extensions: 115521661 Number of successful extensions: 291466 Number of sequences better than 1.0e-05: 1798 Number of HSP's gapped: 288004 Number of HSP's successfully gapped: 1854 Length of query: 443 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 304 Effective length of database: 1,751,175,118 Effective search space: 532357235872 Effective search space used: 532357235872 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 133 (55.8 bits)