BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0173.0003.p (453 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K8Q0.1 B3K8Q0_9BACI Replicative DNA helicase 828 0.0 B1DC40.1 B1DC40_9BACL Replicative DNA helicase 730 0.0 Q9K5Q9.1 Q9K5Q9_BACHD Replicative DNA helicase 638 0.0 Q5WAH9.1 Q5WAH9_BACSK Replicative DNA helicase 634 e-180 A7GVN1.1 A7GVN1_BACCN Replicative DNA helicase 626 e-177 >B3K8Q0.1 B3K8Q0_9BACI Replicative DNA helicase Length = 454 Score = 828 bits (2139), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/453 (87%), Positives = 426/453 (94%) Query: 1 MGGDLFFDRIPPQNLEAEQAVIGAVLLQDEALITAMERVNTEDFYDKPHQMIFEAMVQLG 60 MGG+L+FDR+PPQNLEAEQAV+GA+LLQ EALITAMERV EDFYDK HQMI+E MVQLG Sbjct: 1 MGGELYFDRVPPQNLEAEQAVLGAILLQSEALITAMERVQAEDFYDKSHQMIYEVMVQLG 60 Query: 61 EESQPIDLVTLTSRLQDKGQLEDIGGVSYLAKLAHAVPTAANVDYYAQIIEEKAMLRRLI 120 E +QPIDLVTLTS LQDKGQLE+IGGVSYLAKLAHAVPTAANVDYYAQIIEEK+MLRRLI Sbjct: 61 EGNQPIDLVTLTSLLQDKGQLEEIGGVSYLAKLAHAVPTAANVDYYAQIIEEKSMLRRLI 120 Query: 121 RTATQIVSEGYTGGEDVANMLSDAERRILEISNRRSGSGFIAIRDVLMQVFDRVELLHQN 180 RTATQIVSEGYTGGEDV+ MLS+AERRILEISNRR+GSGFIAIRDVLM+VF++VE+LHQN Sbjct: 121 RTATQIVSEGYTGGEDVSGMLSEAERRILEISNRRTGSGFIAIRDVLMEVFEKVEVLHQN 180 Query: 181 KGGTSGIPTGFVDLDHMTNGFQRNDLIIVAARPSVGKTAFALNIAQNVAVRAKETVAIFS 240 +G T+GIP+GFVDLD MT+GFQRNDLIIVAARPSVGKTAFALNIAQNVA+RAKETVAIFS Sbjct: 181 RGNTTGIPSGFVDLDKMTSGFQRNDLIIVAARPSVGKTAFALNIAQNVAIRAKETVAIFS 240 Query: 241 LEMSAPQLVQRMICAEANLDANIMRTGDFKSDDDWSKLTMGIQSLSESEIYIDDTPGVTV 300 LEMSAPQLVQRMICAEANLDA +MR GDFK D+DWSKLTMGI +LSE+EIYIDDTPGVTV Sbjct: 241 LEMSAPQLVQRMICAEANLDAGVMRNGDFKGDEDWSKLTMGIAALSEAEIYIDDTPGVTV 300 Query: 301 TDIRAKCRRLKKEKGLGMIVIDYLQLIQGRGKAGENRQQEVSEISRTLKQIARELDVPVI 360 DIRAKCRRLKKEKGLGMI+IDYLQLI GRGK GENRQQEVSEISRTLKQIAREL+VPVI Sbjct: 301 ADIRAKCRRLKKEKGLGMILIDYLQLIHGRGKPGENRQQEVSEISRTLKQIARELEVPVI 360 Query: 361 ALSQLSRGVEQRQDKRPMMSDLRESGSIEQDADIVAFLYRDDYYNQDTEKKNXXXXXXAK 420 ALSQLSRGVEQRQDKRPMMSDLRESGSIEQDADIVAFLYRDDYYNQ+TEKKN AK Sbjct: 361 ALSQLSRGVEQRQDKRPMMSDLRESGSIEQDADIVAFLYRDDYYNQETEKKNIIEIIIAK 420 Query: 421 QRNGPVGTVELVFLKNFNKFVNYERAHNEPFAG 453 QRNGPVGTVELVFLKNFNKFVNYER H + FA Sbjct: 421 QRNGPVGTVELVFLKNFNKFVNYERTHADAFAA 453 >B1DC40.1 B1DC40_9BACL Replicative DNA helicase Length = 457 Score = 730 bits (1884), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/448 (78%), Positives = 400/448 (89%), Gaps = 2/448 (0%) Query: 4 DLFFDRIPPQNLEAEQAVIGAVLLQDEALITAMERVNTEDFYDKPHQMIFEAMVQLGEES 63 +L FDR+PPQNLEAEQAVIGA+LLQ EALITAMER+ +EDFY PHQ I+EAMV+LGE Sbjct: 7 ELMFDRVPPQNLEAEQAVIGAILLQSEALITAMERLRSEDFYSVPHQQIYEAMVELGESG 66 Query: 64 QPIDLVTLTSRLQDKGQLEDIGGVSYLAKLAHAVPTAANVDYYAQIIEEKAMLRRLIRTA 123 QP+DL+TLT+ LQD+ +E+IGGVSYLAKLA AVPTAANVDYYAQI+EEK+MLRRLIRTA Sbjct: 67 QPVDLITLTAYLQDRQLIEEIGGVSYLAKLASAVPTAANVDYYAQIVEEKSMLRRLIRTA 126 Query: 124 TQIVSEGYTGGEDVANMLSDAERRILEISNRRSGSGFIAIRDVLMQVFDRVELLHQNKG- 182 T IVS+GY ++V+ +L DAER+ILEISNRRS SGFI+IRDVLM+VF++VE L+ KG Sbjct: 127 TNIVSDGYASTDEVSILLGDAERKILEISNRRSSSGFISIRDVLMEVFEKVETLYNQKGA 186 Query: 183 GTSGIPTGFVDLDHMTNGFQRNDLIIVAARPSVGKTAFALNIAQNVAVRAKETVAIFSLE 242 GT+GIP+GFVDLD MT GFQR+DLII+AARPSVGKTAFALNIAQNV VRA+ETVAIFSLE Sbjct: 187 GTTGIPSGFVDLDKMTAGFQRSDLIIIAARPSVGKTAFALNIAQNVGVRARETVAIFSLE 246 Query: 243 MSAPQLVQRMICAEANLDANIMRTGDFKSDDDWSKLTMGIQSLSESEIYIDDTPGVTVTD 302 MSA QLVQRM+CAE+N+DA MRTG + DD W KLTM I +LSE+ ++IDDTPG+TV D Sbjct: 247 MSAAQLVQRMVCAESNVDATRMRTGQLEGDD-WEKLTMAIGALSEANVFIDDTPGITVAD 305 Query: 303 IRAKCRRLKKEKGLGMIVIDYLQLIQGRGKAGENRQQEVSEISRTLKQIARELDVPVIAL 362 IRAKCRRLKKEKGLGMI+IDYLQLIQGRGKAGENRQQEVSEISRTLKQIAREL+VPVIAL Sbjct: 306 IRAKCRRLKKEKGLGMILIDYLQLIQGRGKAGENRQQEVSEISRTLKQIARELEVPVIAL 365 Query: 363 SQLSRGVEQRQDKRPMMSDLRESGSIEQDADIVAFLYRDDYYNQDTEKKNXXXXXXAKQR 422 SQLSRGVEQRQDKRPMMSDLRESGSIEQDADIV FLYRDDYY++++EKKN AKQR Sbjct: 366 SQLSRGVEQRQDKRPMMSDLRESGSIEQDADIVGFLYRDDYYDKESEKKNIIEIILAKQR 425 Query: 423 NGPVGTVELVFLKNFNKFVNYERAHNEP 450 NGPVGTVELVFLK FNKFV+ +R H++P Sbjct: 426 NGPVGTVELVFLKQFNKFVSLDRTHDDP 453 >Q9K5Q9.1 Q9K5Q9_BACHD Replicative DNA helicase Length = 454 Score = 638 bits (1645), Expect = 0.0, Method: Compositional matrix adjust. Identities = 300/446 (67%), Positives = 370/446 (82%), Gaps = 1/446 (0%) Query: 4 DLFFDRIPPQNLEAEQAVIGAVLLQDEALITAMERVNTEDFYDKPHQMIFEAMVQLGEES 63 DLF DR PPQN+EAEQAV+GA+ L+D AL+TA ER+ EDFY HQ I++ M+ L E+ Sbjct: 3 DLFADRTPPQNIEAEQAVLGAIFLEDHALVTASERLAPEDFYRAAHQRIYQVMLDLAEKG 62 Query: 64 QPIDLVTLTSRLQDKGQLEDIGGVSYLAKLAHAVPTAANVDYYAQIIEEKAMLRRLIRTA 123 +P+DLVT+T+ LQD+ L+D+GGV+YL LA+AVPTAANV+YY++I+EEK++LRRLIR A Sbjct: 63 EPVDLVTVTAELQDRKALDDVGGVAYLGDLANAVPTAANVEYYSKIVEEKSLLRRLIRVA 122 Query: 124 TQIVSEGYTGGEDVANMLSDAERRILEISNRRSGSGFIAIRDVLMQVFDRVELLHQNKGG 183 T I EGY E+V +L DAE+ IL+++ R++ S FI+I+DVL++ +D++E+L KG Sbjct: 123 TNIAQEGYASEEEVDAILDDAEKTILDVAQRKNSSAFISIKDVLVETYDKIEMLQNQKGE 182 Query: 184 TSGIPTGFVDLDHMTNGFQRNDLIIVAARPSVGKTAFALNIAQNVAVRAKETVAIFSLEM 243 +GIPTGF DLD MT GFQRNDLIIVAARPSVGKTAFALNI+QNVA + E VAIFSLEM Sbjct: 183 ITGIPTGFKDLDRMTAGFQRNDLIIVAARPSVGKTAFALNISQNVATKTDENVAIFSLEM 242 Query: 244 SAPQLVQRMICAEANLDANIMRTGDFKSDDDWSKLTMGIQSLSESEIYIDDTPGVTVTDI 303 A QLVQRM+CAE N+DA MRTG +++DW KLTM + SL+ + IYIDDTPG+ V +I Sbjct: 243 GASQLVQRMLCAEGNIDAQRMRTGAL-TEEDWQKLTMAMGSLARAGIYIDDTPGIKVNEI 301 Query: 304 RAKCRRLKKEKGLGMIVIDYLQLIQGRGKAGENRQQEVSEISRTLKQIARELDVPVIALS 363 RAKCRRLK+EKGLGMI+IDYLQLIQG G++GENRQQEVSEISR+LK +AREL+VPVIALS Sbjct: 302 RAKCRRLKQEKGLGMILIDYLQLIQGNGRSGENRQQEVSEISRSLKGLARELEVPVIALS 361 Query: 364 QLSRGVEQRQDKRPMMSDLRESGSIEQDADIVAFLYRDDYYNQDTEKKNXXXXXXAKQRN 423 QLSRGVE RQDKRPMMSD+RESGSIEQDADIVAFLYRDDYY+++TE +N AKQRN Sbjct: 362 QLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDKETENQNIIEIIIAKQRN 421 Query: 424 GPVGTVELVFLKNFNKFVNYERAHNE 449 GPVGTVEL F+K +NKFVN +R H+E Sbjct: 422 GPVGTVELAFIKEYNKFVNLDRHHDE 447 >Q5WAH9.1 Q5WAH9_BACSK Replicative DNA helicase Length = 453 Score = 634 bits (1635), Expect = e-180, Method: Compositional matrix adjust. Identities = 302/446 (67%), Positives = 369/446 (82%), Gaps = 1/446 (0%) Query: 4 DLFFDRIPPQNLEAEQAVIGAVLLQDEALITAMERVNTEDFYDKPHQMIFEAMVQLGEES 63 DL +R PPQN+EAEQAV+GA+ L D AL TA ER+ EDFY HQ I+E M+ LGE+ Sbjct: 3 DLLTERTPPQNIEAEQAVLGAIFLADHALTTASERLMPEDFYRASHQRIYEVMLDLGEKG 62 Query: 64 QPIDLVTLTSRLQDKGQLEDIGGVSYLAKLAHAVPTAANVDYYAQIIEEKAMLRRLIRTA 123 +P+DLVT+TS LQ++G L+DIGGV+YLA +A +VPTAANV+YY++I+EEK++LRRLIR A Sbjct: 63 EPVDLVTVTSELQNRGWLDDIGGVAYLADVAESVPTAANVEYYSRIVEEKSLLRRLIRVA 122 Query: 124 TQIVSEGYTGGEDVANMLSDAERRILEISNRRSGSGFIAIRDVLMQVFDRVELLHQNKGG 183 T I EGY ++V +L AE+ ILE++ R++ S F++I+DVL++ +D++E+L Q +G Sbjct: 123 TNIAKEGYASEDEVDAILDQAEKTILEVAQRKNTSSFVSIKDVLLETYDQIEMLQQTRGE 182 Query: 184 TSGIPTGFVDLDHMTNGFQRNDLIIVAARPSVGKTAFALNIAQNVAVRAKETVAIFSLEM 243 +GI TGF +LD MT GFQRNDLIIVAARPSVGKTAFALNIAQNVA + ETVAIFSLEM Sbjct: 183 ITGIATGFTELDTMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDETVAIFSLEM 242 Query: 244 SAPQLVQRMICAEANLDANIMRTGDFKSDDDWSKLTMGIQSLSESEIYIDDTPGVTVTDI 303 A QLV RM+CAE N+DA MRTG + ++DW KL+M + SLS++ IYIDDTPGV V +I Sbjct: 243 GASQLVTRMLCAEGNIDAQRMRTGALE-EEDWHKLSMAMGSLSKAGIYIDDTPGVKVGEI 301 Query: 304 RAKCRRLKKEKGLGMIVIDYLQLIQGRGKAGENRQQEVSEISRTLKQIARELDVPVIALS 363 RAKCRRLK+EKGLGMI+IDYLQLIQG G++GENRQQEVSEISRTLK IAREL+VPVIALS Sbjct: 302 RAKCRRLKQEKGLGMILIDYLQLIQGNGRSGENRQQEVSEISRTLKAIARELEVPVIALS 361 Query: 364 QLSRGVEQRQDKRPMMSDLRESGSIEQDADIVAFLYRDDYYNQDTEKKNXXXXXXAKQRN 423 QLSRGVE RQDKRPMMSD+RESGSIEQDADIVAFLYRDDYY+++TE KN AKQRN Sbjct: 362 QLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDKETENKNIIEIIIAKQRN 421 Query: 424 GPVGTVELVFLKNFNKFVNYERAHNE 449 GPVGTVEL F+K +NKFVN +R H+E Sbjct: 422 GPVGTVELAFVKEYNKFVNLDRRHDE 447 >A7GVN1.1 A7GVN1_BACCN Replicative DNA helicase Length = 453 Score = 626 bits (1615), Expect = e-177, Method: Compositional matrix adjust. Identities = 305/449 (67%), Positives = 367/449 (81%), Gaps = 1/449 (0%) Query: 4 DLFFDRIPPQNLEAEQAVIGAVLLQDEALITAMERVNTEDFYDKPHQMIFEAMVQLGEES 63 D+ DR PP N+EAEQAV+GA+LL+ +AL TA E + E FY HQ IFE M+ L ++ Sbjct: 3 DVLADRTPPHNIEAEQAVLGAILLEQDALTTASELLLPESFYRTAHQKIFEIMLGLSDKG 62 Query: 64 QPIDLVTLTSRLQDKGQLEDIGGVSYLAKLAHAVPTAANVDYYAQIIEEKAMLRRLIRTA 123 +P+DLVT+T+ L D+G LE++GGVSYLA+LA AVPTAANV+YYA+II EKA+LRRLIRTA Sbjct: 63 EPVDLVTVTAVLSDRGLLEEVGGVSYLAELAEAVPTAANVEYYARIIAEKALLRRLIRTA 122 Query: 124 TQIVSEGYTGGEDVANMLSDAERRILEISNRRSGSGFIAIRDVLMQVFDRVELLHQNKGG 183 T IVS+GY +DV +L++AE++ILE+S++ + F I+DVL++ +D++ELLH KG Sbjct: 123 THIVSDGYEREDDVEGLLNEAEKKILEVSHQTNAKAFQNIKDVLVEAYDKIELLHNQKGE 182 Query: 184 TSGIPTGFVDLDHMTNGFQRNDLIIVAARPSVGKTAFALNIAQNVAVRAKETVAIFSLEM 243 +GIPTGF +LD MT GFQRNDLIIVAARPSVGKTAF+LNIAQNVA + E VAIFSLEM Sbjct: 183 ITGIPTGFTELDRMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSLEM 242 Query: 244 SAPQLVQRMICAEANLDANIMRTGDFKSDDDWSKLTMGIQSLSESEIYIDDTPGVTVTDI 303 A QLV RM+CAE N+DA +RTG S +DW+KLTM + SLS + IYIDDTPG+ V++I Sbjct: 243 GADQLVMRMLCAEGNIDAQRLRTGSLTS-EDWAKLTMAMGSLSNAGIYIDDTPGIRVSEI 301 Query: 304 RAKCRRLKKEKGLGMIVIDYLQLIQGRGKAGENRQQEVSEISRTLKQIARELDVPVIALS 363 RAKCRRLK+E+GLGMI+IDYLQLIQG GK GENRQQEVSEISRTLK IAREL VPVIALS Sbjct: 302 RAKCRRLKQEQGLGMILIDYLQLIQGSGKPGENRQQEVSEISRTLKGIARELQVPVIALS 361 Query: 364 QLSRGVEQRQDKRPMMSDLRESGSIEQDADIVAFLYRDDYYNQDTEKKNXXXXXXAKQRN 423 QLSRGVE RQDKRPMMSD+RESGSIEQDADIVAFLYRDDYY+++TE KN AKQRN Sbjct: 362 QLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDRETENKNTIEIIIAKQRN 421 Query: 424 GPVGTVELVFLKNFNKFVNYERAHNEPFA 452 GPVGTVEL F+K FNKFVN ER ++ A Sbjct: 422 GPVGTVELAFVKEFNKFVNLERRFDDGHA 450 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.135 0.371 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,476,343,361 Number of extensions: 98198481 Number of successful extensions: 315075 Number of sequences better than 1.0e-05: 2147 Number of HSP's gapped: 307441 Number of HSP's successfully gapped: 2216 Length of query: 453 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 314 Effective length of database: 1,751,175,118 Effective search space: 549868987052 Effective search space used: 549868987052 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 133 (55.8 bits)