BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0171.0007.p (245 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KFN0.1 B3KFN0_9BACI Silent information regulator protein Sir2 341 3e-92 Q97MB4.1 NPD_CLOAB NAD-dependent deacetylase EC=3.5.1.- 292 2e-77 Q899G3.1 NPD_CLOTE NAD-dependent deacetylase EC=3.5.1.- 288 4e-76 B9DXH0.1 B9DXH0_CLOK1 Putative uncharacterized protein 287 7e-76 A5N3U0.1 A5N3U0_CLOK5 NpdA EC=3.5.1.- 287 7e-76 >B3KFN0.1 B3KFN0_9BACI Silent information regulator protein Sir2 Length = 250 Score = 341 bits (874), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 156/244 (63%), Positives = 190/244 (77%) Query: 2 DPLQTLVSWIKDSGSIVFFGGAGTSTESGIPDFRSAAGLYQTQHNSPYPPEVMLSRSFFM 61 + ++ L +WI+ S IVFFGGAGTSTESGIPDFRSAAGLYQ++H SPYPPEVMLS +FFM Sbjct: 5 EKIEQLATWIEASDYIVFFGGAGTSTESGIPDFRSAAGLYQSEHQSPYPPEVMLSHTFFM 64 Query: 62 SSPDIFFDFYRSKMIHPEAKPNGAHQLLAQLERDGKLKAVITQNIDGLHQLAGSRRVLEL 121 P++F+DFYRSKM+HP A+PNG H+LL++LE DGKLKAVITQNIDGLHQ AG VLEL Sbjct: 65 QHPEVFYDFYRSKMLHPLAQPNGCHRLLSRLEHDGKLKAVITQNIDGLHQSAGCSEVLEL 124 Query: 122 HGSIHRNHCMDCSRYYGLDQVLASEAGVPRCPECGGIIKPDVVLYEEELDHDXXXXXXXX 181 HGS+HRN+CMDCSR+Y L ++L + VPRC +CGG+++PDVVLYEEELD + Sbjct: 125 HGSVHRNYCMDCSRFYSLQEILDIKETVPRCKDCGGLVRPDVVLYEEELDQNVIMRSIQE 184 Query: 182 XXXXXXXXXGGTSLTVQPAASLITYFRGRHTVLLNGDPTPYDHQADLIITDRIGAVMGKI 241 GGTSLTV PAASLI+YF G LLN DPTPYDH+A L+I DRIG VM ++ Sbjct: 185 ISTADLLIIGGTSLTVHPAASLISYFHGSKVALLNADPTPYDHRAGLLIADRIGQVMTQV 244 Query: 242 QELL 245 +L+ Sbjct: 245 DKLI 248 >Q97MB4.1 NPD_CLOAB NAD-dependent deacetylase EC=3.5.1.- Length = 245 Score = 292 bits (748), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 134/238 (56%), Positives = 168/238 (70%) Query: 1 MDPLQTLVSWIKDSGSIVFFGGAGTSTESGIPDFRSAAGLYQTQHNSPYPPEVMLSRSFF 60 +D + L + +S SIVFFGGAG STES IPDFRS GLY+T++N YPPEVMLS +FF Sbjct: 4 LDKINELKKIVAESSSIVFFGGAGVSTESNIPDFRSENGLYKTKNNFSYPPEVMLSHTFF 63 Query: 61 MSSPDIFFDFYRSKMIHPEAKPNGAHQLLAQLERDGKLKAVITQNIDGLHQLAGSRRVLE 120 + + FF+FYR KMI +AKPN AH LA++E GKLKA++TQNIDGLHQLAGS+ V E Sbjct: 64 KNHTEDFFEFYREKMIFKDAKPNAAHYSLAKIEEQGKLKAIVTQNIDGLHQLAGSKNVYE 123 Query: 121 LHGSIHRNHCMDCSRYYGLDQVLASEAGVPRCPECGGIIKPDVVLYEEELDHDXXXXXXX 180 LHGSIHRN+CMDC + + L+ V+ SE +P+C +CGGI+KPDVVLYEE LD Sbjct: 124 LHGSIHRNYCMDCGKSFDLEYVIKSETTIPKCDKCGGIVKPDVVLYEEGLDDSIIQNSVK 183 Query: 181 XXXXXXXXXXGGTSLTVQPAASLITYFRGRHTVLLNGDPTPYDHQADLIITDRIGAVM 238 GGTSL V PAA LI YF+G +L+N T YD++ADL+I+D IG V+ Sbjct: 184 AISEADTLIVGGTSLVVYPAAGLIRYFKGNKLILINKSATAYDNEADLVISDSIGKVL 241 >Q899G3.1 NPD_CLOTE NAD-dependent deacetylase EC=3.5.1.- Length = 247 Score = 288 bits (736), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 136/245 (55%), Positives = 171/245 (69%) Query: 1 MDPLQTLVSWIKDSGSIVFFGGAGTSTESGIPDFRSAAGLYQTQHNSPYPPEVMLSRSFF 60 MD + L IK S +IVFFGGAG STES IPDFRS GLY+T+ N Y PEVMLS SFF Sbjct: 1 MDTRKNLKELIKSSSNIVFFGGAGVSTESNIPDFRSEEGLYKTKSNFSYSPEVMLSHSFF 60 Query: 61 MSSPDIFFDFYRSKMIHPEAKPNGAHQLLAQLERDGKLKAVITQNIDGLHQLAGSRRVLE 120 + FFDFY+ KMI+ AKPN AH LA+LE+ GKLKA+ITQNIDGLHQLAGS+ V+E Sbjct: 61 KEHTEDFFDFYKEKMIYKYAKPNLAHHALAKLEKVGKLKAIITQNIDGLHQLAGSKNVIE 120 Query: 121 LHGSIHRNHCMDCSRYYGLDQVLASEAGVPRCPECGGIIKPDVVLYEEELDHDXXXXXXX 180 LHG + RN+CMDC++++ L+ +L ++ VP+C CGGI+KPDVVLYEE L+ D Sbjct: 121 LHGGVGRNYCMDCNKFFDLNYILNNKEVVPKCDVCGGIVKPDVVLYEEPLNMDNINNAVR 180 Query: 181 XXXXXXXXXXGGTSLTVQPAASLITYFRGRHTVLLNGDPTPYDHQADLIITDRIGAVMGK 240 GGTSL V PAA+LI Y++G VL+N TPYD +A ++I D IG+++G Sbjct: 181 YVENSDVLIVGGTSLVVYPAANLIHYYKGNKLVLINKSSTPYDRKAQIVINDSIGSILGG 240 Query: 241 IQELL 245 I E L Sbjct: 241 IVEEL 245 >B9DXH0.1 B9DXH0_CLOK1 Putative uncharacterized protein Length = 241 Score = 287 bits (734), Expect = 7e-76, Method: Compositional matrix adjust. Identities = 133/237 (56%), Positives = 168/237 (70%) Query: 5 QTLVSWIKDSGSIVFFGGAGTSTESGIPDFRSAAGLYQTQHNSPYPPEVMLSRSFFMSSP 64 + L S + S +IVF GGAG STES IPDFRS AG+Y+T++N YPPEVMLS +FFMS Sbjct: 4 EKLKSVVDSSENIVFLGGAGVSTESNIPDFRSEAGIYKTKNNFSYPPEVMLSHTFFMSHT 63 Query: 65 DIFFDFYRSKMIHPEAKPNGAHQLLAQLERDGKLKAVITQNIDGLHQLAGSRRVLELHGS 124 + FFDFYR KMI+ +AKPN H LA+LE+ GKLKA+ITQNIDGLHQ+AGS VLELHGS Sbjct: 64 EDFFDFYRKKMIYKDAKPNDTHYALAELEKRGKLKAIITQNIDGLHQMAGSHNVLELHGS 123 Query: 125 IHRNHCMDCSRYYGLDQVLASEAGVPRCPECGGIIKPDVVLYEEELDHDXXXXXXXXXXX 184 IHRN+C C++++ LD V+ S +P+C +C G++KPDVVLYEE LD D Sbjct: 124 IHRNYCTRCNKFFDLDYVIKSTNLIPKCDKCNGLVKPDVVLYEESLDMDVLNNSVEYIRK 183 Query: 185 XXXXXXGGTSLTVQPAASLITYFRGRHTVLLNGDPTPYDHQADLIITDRIGAVMGKI 241 GGTSL V PAA L+ YF G + VL+N TPYD++A+++I D IG V+ I Sbjct: 184 ADILIVGGTSLVVYPAAGLVDYFNGSNLVLINKSTTPYDNKANIVIHDSIGKVLKSI 240 >A5N3U0.1 A5N3U0_CLOK5 NpdA EC=3.5.1.- Length = 241 Score = 287 bits (734), Expect = 7e-76, Method: Compositional matrix adjust. Identities = 133/237 (56%), Positives = 168/237 (70%) Query: 5 QTLVSWIKDSGSIVFFGGAGTSTESGIPDFRSAAGLYQTQHNSPYPPEVMLSRSFFMSSP 64 + L S + S +IVF GGAG STES IPDFRS AG+Y+T++N YPPEVMLS +FFMS Sbjct: 4 EKLKSVVDSSENIVFLGGAGVSTESNIPDFRSEAGIYKTKNNFSYPPEVMLSHTFFMSHT 63 Query: 65 DIFFDFYRSKMIHPEAKPNGAHQLLAQLERDGKLKAVITQNIDGLHQLAGSRRVLELHGS 124 + FFDFYR KMI+ +AKPN H LA+LE+ GKLKA+ITQNIDGLHQ+AGS VLELHGS Sbjct: 64 EDFFDFYRKKMIYKDAKPNDTHYALAELEKRGKLKAIITQNIDGLHQMAGSHNVLELHGS 123 Query: 125 IHRNHCMDCSRYYGLDQVLASEAGVPRCPECGGIIKPDVVLYEEELDHDXXXXXXXXXXX 184 IHRN+C C++++ LD V+ S +P+C +C G++KPDVVLYEE LD D Sbjct: 124 IHRNYCTRCNKFFDLDYVIKSTNLIPKCDKCNGLVKPDVVLYEESLDMDVLNNSVEYIRK 183 Query: 185 XXXXXXGGTSLTVQPAASLITYFRGRHTVLLNGDPTPYDHQADLIITDRIGAVMGKI 241 GGTSL V PAA L+ YF G + VL+N TPYD++A+++I D IG V+ I Sbjct: 184 ADILIVGGTSLVVYPAAGLVDYFNGSNLVLINKSTTPYDNKANIVIHDSIGKVLKSI 240 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.138 0.420 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,456,369,117 Number of extensions: 56438732 Number of successful extensions: 136998 Number of sequences better than 1.0e-05: 1932 Number of HSP's gapped: 132848 Number of HSP's successfully gapped: 1933 Length of query: 245 Length of database: 3,060,696,203 Length adjustment: 132 Effective length of query: 113 Effective length of database: 1,817,122,223 Effective search space: 205334811199 Effective search space used: 205334811199 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 129 (54.3 bits)