BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0171.0006.p (333 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KFN1.1 B3KFN1_9BACI Aldo/keto reductase 555 e-156 Q2BEA8.1 Q2BEA8_9BACI YccK 523 e-147 B1D9S0.1 B1D9S0_9BACL Aldo/keto reductase 497 e-139 B1D6P6.1 B1D6P6_9BACL Aldo/keto reductase 495 e-138 C4C6I4.1 C4C6I4_9FUSO Predicted oxidoreductase similar to aryl-a... 483 e-135 >B3KFN1.1 B3KFN1_9BACI Aldo/keto reductase Length = 340 Score = 555 bits (1431), Expect = e-156, Method: Compositional matrix adjust. Identities = 264/332 (79%), Positives = 299/332 (90%) Query: 1 MVYVANDERYERMRYNRTGRSGLKLPAISLGLWHNFGGINTYENGREMITRSFDLGITHF 60 + YVA+++RYE M+YNR GRSGLKLPAISLGLWHNFGG++TYENGR MITRSFDLGITHF Sbjct: 3 VTYVASEDRYEGMKYNRVGRSGLKLPAISLGLWHNFGGVDTYENGRNMITRSFDLGITHF 62 Query: 61 DLANNYGPPAGSAEEMFGKVLARDLAPYRDELVVSTKAGYYMWPGPYGDWGSRKYMLASL 120 DLANNYGPPAGSAEE FGKVL+RDL YRDE++VS+KAGYYMWPGPYGD+GSRKY+++SL Sbjct: 63 DLANNYGPPAGSAEETFGKVLSRDLKAYRDEIIVSSKAGYYMWPGPYGDFGSRKYLVSSL 122 Query: 121 DQSLKRLGLDYVDIFYSHRPDPETPLEETMGALDTAVRSGKALYVGLSNYTAEQTAEAVR 180 DQSLKR+GLDYVDIFY HR DPETPLEETM ALD VRSGKALYVG+SNY+ E+T EA+ Sbjct: 123 DQSLKRMGLDYVDIFYHHRMDPETPLEETMAALDHLVRSGKALYVGVSNYSPEKTREAIS 182 Query: 181 ILTSLGTPLLIHQPRYSMLDRWIEGGLQDVLEEHGIGSIAFTPLAQGLLTSKYLNGIPED 240 IL SLGTPLLIHQP YSMLDRW+E GL DVLEE+G+GSIAFTPLAQGLLT+KYLNG+P D Sbjct: 183 ILKSLGTPLLIHQPSYSMLDRWVENGLLDVLEENGVGSIAFTPLAQGLLTNKYLNGVPVD 242 Query: 241 SRAAGPSASLNESRITPEVLRKIHALNQLAVSRGLSLAQFALLWTLRGGRVTSALIGASR 300 SRAA S LNES ITPEVLRKI ALNQ+A +R SLAQFAL W LRGGRVTSALIGAS+ Sbjct: 243 SRAASASVFLNESNITPEVLRKIRALNQIAQARNQSLAQFALAWVLRGGRVTSALIGASK 302 Query: 301 VSQIEENIAALSHGEFSQEELDRIETILKTDS 332 VSQIE+N+AAL++ EFS+EELDRIE ILKT++ Sbjct: 303 VSQIEDNVAALNNLEFSKEELDRIEAILKTEN 334 >Q2BEA8.1 Q2BEA8_9BACI YccK Length = 330 Score = 523 bits (1348), Expect = e-147, Method: Compositional matrix adjust. Identities = 241/330 (73%), Positives = 291/330 (88%) Query: 1 MVYVANDERYERMRYNRTGRSGLKLPAISLGLWHNFGGINTYENGREMITRSFDLGITHF 60 MVY+A ++RYE M+YNR+GRSGL+LPAISLGLWHNFGG +TYENGREM+ ++FDLGITHF Sbjct: 1 MVYLAGEKRYETMKYNRSGRSGLRLPAISLGLWHNFGGTDTYENGREMLRKAFDLGITHF 60 Query: 61 DLANNYGPPAGSAEEMFGKVLARDLAPYRDELVVSTKAGYYMWPGPYGDWGSRKYMLASL 120 DLANNYGP AGSAEEMFG+++ D APYRDE+++STKAGYYMWPGPYG+WGSRKY+++SL Sbjct: 61 DLANNYGPTAGSAEEMFGRMMKSDFAPYRDEMIISTKAGYYMWPGPYGEWGSRKYLISSL 120 Query: 121 DQSLKRLGLDYVDIFYSHRPDPETPLEETMGALDTAVRSGKALYVGLSNYTAEQTAEAVR 180 DQSLKR+GLDYVDIFYSHRPDP+TPLEETMGALD+ VR GKALYVG+S+Y+AEQT EAV+ Sbjct: 121 DQSLKRMGLDYVDIFYSHRPDPDTPLEETMGALDSIVRQGKALYVGISSYSAEQTEEAVK 180 Query: 181 ILTSLGTPLLIHQPRYSMLDRWIEGGLQDVLEEHGIGSIAFTPLAQGLLTSKYLNGIPED 240 IL LGTPL+IHQP YSML+RWIE GLQDVL+++G GSIAF PLAQGLLT+KY++GIP D Sbjct: 181 ILNRLGTPLVIHQPSYSMLNRWIEDGLQDVLDKNGAGSIAFCPLAQGLLTNKYIDGIPAD 240 Query: 241 SRAAGPSASLNESRITPEVLRKIHALNQLAVSRGLSLAQFALLWTLRGGRVTSALIGASR 300 SRAA + +L ++T + + K+ L++LA RG SLAQ +L W LRGGRVTSALIGASR Sbjct: 241 SRAASKTGALQGDQVTEQTIEKVRKLHELASERGQSLAQMSLAWVLRGGRVTSALIGASR 300 Query: 301 VSQIEENIAALSHGEFSQEELDRIETILKT 330 VSQIEEN+AAL + EF+ EEL+RIE ILK+ Sbjct: 301 VSQIEENVAALDNLEFTAEELNRIEDILKS 330 >B1D9S0.1 B1D9S0_9BACL Aldo/keto reductase Length = 344 Score = 497 bits (1279), Expect = e-139, Method: Compositional matrix adjust. Identities = 236/328 (71%), Positives = 272/328 (82%) Query: 1 MVYVANDERYERMRYNRTGRSGLKLPAISLGLWHNFGGINTYENGREMITRSFDLGITHF 60 M Y A+ R+E M+Y R G+SGLKLPA+SLGLWHNFGG + ENGR MI R+FDLGITHF Sbjct: 16 MTYAADKSRFEDMKYFRVGKSGLKLPAVSLGLWHNFGGNDRLENGRAMIHRAFDLGITHF 75 Query: 61 DLANNYGPPAGSAEEMFGKVLARDLAPYRDELVVSTKAGYYMWPGPYGDWGSRKYMLASL 120 DLANNYGPP GSAEE FGKVL +D+A YRD++++STKAGYYMW GPYGDWGSRKY+++SL Sbjct: 76 DLANNYGPPPGSAEETFGKVLKQDMAAYRDQMIISTKAGYYMWEGPYGDWGSRKYLVSSL 135 Query: 121 DQSLKRLGLDYVDIFYSHRPDPETPLEETMGALDTAVRSGKALYVGLSNYTAEQTAEAVR 180 DQSLKR+ L+YVDIFY HRPDPETPLEETM ALD VRSGKALYVGLSNY+AEQTA+A Sbjct: 136 DQSLKRMDLEYVDIFYHHRPDPETPLEETMAALDHIVRSGKALYVGLSNYSAEQTAQASA 195 Query: 181 ILTSLGTPLLIHQPRYSMLDRWIEGGLQDVLEEHGIGSIAFTPLAQGLLTSKYLNGIPED 240 IL LGTP LIHQP YSM +RWIE GLQDVL++ GIGSI F+PLA GLLT++YL+GIP D Sbjct: 196 ILKQLGTPCLIHQPSYSMFNRWIEDGLQDVLDQEGIGSIVFSPLAGGLLTNRYLDGIPTD 255 Query: 241 SRAAGPSASLNESRITPEVLRKIHALNQLAVSRGLSLAQFALLWTLRGGRVTSALIGASR 300 SRA GPS LN + IT E L K+ ALN++A SRG SLAQ AL W LRGGRVTSALIGASR Sbjct: 256 SRAGGPSVFLNSNSITEEKLAKVRALNEIAQSRGQSLAQMALAWVLRGGRVTSALIGASR 315 Query: 301 VSQIEENIAALSHGEFSQEELDRIETIL 328 V QI++N+A LS +FS +EL IE IL Sbjct: 316 VEQIDDNVAVLSRLDFSDDELQAIENIL 343 >B1D6P6.1 B1D6P6_9BACL Aldo/keto reductase Length = 329 Score = 495 bits (1275), Expect = e-138, Method: Compositional matrix adjust. Identities = 233/329 (70%), Positives = 268/329 (81%) Query: 1 MVYVANDERYERMRYNRTGRSGLKLPAISLGLWHNFGGINTYENGREMITRSFDLGITHF 60 M+Y A ERYE M YNR G+SGLKL AISLGLWHNFGGI+ YENGR M+ R+FDLGITHF Sbjct: 1 MLYTARQERYESMTYNRCGKSGLKLSAISLGLWHNFGGIDKYENGRAMVRRAFDLGITHF 60 Query: 61 DLANNYGPPAGSAEEMFGKVLARDLAPYRDELVVSTKAGYYMWPGPYGDWGSRKYMLASL 120 DLANNYGPP GSAEE FG++L DL+PYRDEL++STKAGYYMWPGPYG+WGS+K +++SL Sbjct: 61 DLANNYGPPPGSAEESFGRMLKDDLSPYRDELIISTKAGYYMWPGPYGEWGSKKSLVSSL 120 Query: 121 DQSLKRLGLDYVDIFYSHRPDPETPLEETMGALDTAVRSGKALYVGLSNYTAEQTAEAVR 180 DQSLKR+G+DYVDIFY HRPDP+TPLEETM ALD VR GKALYVG+SNY EQT EA R Sbjct: 121 DQSLKRMGVDYVDIFYHHRPDPDTPLEETMAALDMIVRQGKALYVGISNYRPEQTREASR 180 Query: 181 ILTSLGTPLLIHQPRYSMLDRWIEGGLQDVLEEHGIGSIAFTPLAQGLLTSKYLNGIPED 240 IL LGTP +IHQP YSM+ RWIE GLQ+VLEE GIGSI F+PL +G+LT +YLNGI D Sbjct: 181 ILKQLGTPCVIHQPNYSMMSRWIEDGLQEVLEEEGIGSIVFSPLEKGILTDRYLNGITSD 240 Query: 241 SRAAGPSASLNESRITPEVLRKIHALNQLAVSRGLSLAQFALLWTLRGGRVTSALIGASR 300 SRAAGPS L I L K+ LN+LA+ RG L+Q AL W LRGGRVTSALIGAS+ Sbjct: 241 SRAAGPSVFLRPEDINETRLAKVKELNKLALERGQKLSQMALAWVLRGGRVTSALIGASK 300 Query: 301 VSQIEENIAALSHGEFSQEELDRIETILK 329 V QIE+ + AL++ FSQEELDRIE ILK Sbjct: 301 VEQIEDAVGALANASFSQEELDRIENILK 329 >C4C6I4.1 C4C6I4_9FUSO Predicted oxidoreductase similar to aryl-alcohol dehydrogenase Length = 331 Score = 483 bits (1244), Expect = e-135, Method: Compositional matrix adjust. Identities = 233/330 (70%), Positives = 270/330 (81%), Gaps = 1/330 (0%) Query: 1 MVYVANDERYERMRYNRTGRSGLKLPAISLGLWHNFGGINTYENGREMITRSFDLGITHF 60 M+Y+A+++RY M+YNR GRSGLKLPAISLGLWHNFG ++ YEN REMI +FDLGITHF Sbjct: 1 MLYLADEKRYASMKYNRCGRSGLKLPAISLGLWHNFGTMDKYENMREMIRTAFDLGITHF 60 Query: 61 DLANNYGPPAGSAEEMFGKVLARDLAPYRDELVVSTKAGYYMWPGPYGDWGSRKYMLASL 120 DLANNYGP GSAEE FGK+LA DL PYRDEL++S+KAGY MWPGPYGDWGS+KY+++SL Sbjct: 61 DLANNYGPIPGSAEENFGKMLADDLKPYRDELIISSKAGYTMWPGPYGDWGSKKYLISSL 120 Query: 121 DQSLKRLGLDYVDIFYSHRPDPETPLEETMGALDTAVRSGKALYVGLSNYTAEQTAEAVR 180 DQSLKR+GLDYVDIFYSHR DP+TPLEETM AL VR GKALYVG+SNYTAEQT EA R Sbjct: 121 DQSLKRMGLDYVDIFYSHRFDPDTPLEETMEALAQIVRQGKALYVGISNYTAEQTREADR 180 Query: 181 ILTSLGTPLLIHQPRYSMLDRWIEGGLQDVLEEHGIGSIAFTPLAQGLLTSKYLNGIPED 240 IL LG LIHQPRYSM +RWIE GLQDVL E GIGSIAF PLAQGLLT+KY+NG+PED Sbjct: 181 ILKELGIKCLIHQPRYSMFERWIEDGLQDVLTEKGIGSIAFCPLAQGLLTNKYINGVPED 240 Query: 241 SRAAGP-SASLNESRITPEVLRKIHALNQLAVSRGLSLAQFALLWTLRGGRVTSALIGAS 299 SRA SLN IT + + K+ L+++A R SLAQ +L WTLRGG+VTSALIGAS Sbjct: 241 SRAGKAWEISLNSDSITADKIEKVKKLDKIAKQRNQSLAQMSLAWTLRGGKVTSALIGAS 300 Query: 300 RVSQIEENIAALSHGEFSQEELDRIETILK 329 + SQI EN+ AL + EF+ EEL+ IE ILK Sbjct: 301 KSSQIIENVHALDNLEFTVEELEAIEKILK 330 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.135 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,032,090,651 Number of extensions: 86697532 Number of successful extensions: 255967 Number of sequences better than 1.0e-05: 6602 Number of HSP's gapped: 244544 Number of HSP's successfully gapped: 6622 Length of query: 333 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 197 Effective length of database: 1,779,438,163 Effective search space: 350549318111 Effective search space used: 350549318111 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 131 (55.1 bits)