BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0168.0014.p (556 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KDJ6.1 B3KDJ6_9BACI Sensor protein EC=2.7.13.3 721 0.0 A6EKP0.1 A6EKP0_9SPHI Sensor protein EC=2.7.13.3 360 1e-97 C1Z0E5.1 C1Z0E5_PEDHE Signal transduction histidine kinase, COG0642 356 3e-96 B8HP17.1 B8HP17_CYAP4 Sensor protein EC=2.7.13.3 337 2e-90 A3IKI3.1 A3IKI3_9CHRO Sensor protein EC=2.7.13.3 331 1e-88 >B3KDJ6.1 B3KDJ6_9BACI Sensor protein EC=2.7.13.3 Length = 559 Score = 721 bits (1861), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/541 (67%), Positives = 426/541 (78%), Gaps = 4/541 (0%) Query: 1 MGVQEPIHILLVDDRPENLLALEAVLESQHYTLVKANSGEEALRCLLKHEFAVIVLDVQM 60 MG EPIHILLVDDRPENLLALEAVL+S+ YTL+KA SGEEALR LLK++FAVIVLDVQM Sbjct: 1 MGFHEPIHILLVDDRPENLLALEAVLDSEQYTLIKATSGEEALRYLLKYDFAVIVLDVQM 60 Query: 61 PGMDGIETAKLIKAREKTKDIPIIFISANSKEAEHLFAGYSAGAIDYMVKPFIPQILKSK 120 PGMDGIETA+LIKAR+KTKDIPIIFISANSK+AEHLFAGYSAGAIDYMVKPFIPQILKSK Sbjct: 61 PGMDGIETARLIKARDKTKDIPIIFISANSKDAEHLFAGYSAGAIDYMVKPFIPQILKSK 120 Query: 121 IEGFVDMYLTTXXXXXXXXXXXXXXXXXXRINGELTRXXXXXXXXXXXXTEFLAMMSHEI 180 IEGFVDMY T +IN EL TEFLAMMSHEI Sbjct: 121 IEGFVDMYRTNNRLKIQSAQLHQKTQELEKINQELVLAKEEAEIAAKAKTEFLAMMSHEI 180 Query: 181 RTPMNGVVGMIDLLMETELAPEQKEYTEIIRKSADTLITVINDILDFTKMESGKMEMEEQ 240 RTPMNGV+GMIDLLM++EL EQ+EY IIR SAD L+ +INDILDF+KMESGKME+EE Sbjct: 181 RTPMNGVIGMIDLLMDSELQDEQREYATIIRNSADALVNIINDILDFSKMESGKMELEEY 240 Query: 241 LFELQTTIQEVFSLFSAEAGKKNLELAYFIDQKLPRLIYGDMARLRQVLINLVANAVKFT 300 F+L++ +QEVF LFS EA KKNLEL Y+I+ ++P +++GDM RLRQVL+NLV+NAVKFT Sbjct: 241 PFDLKSCVQEVFGLFSGEASKKNLELTYYIEDQIPSMVFGDMGRLRQVLVNLVSNAVKFT 300 Query: 301 NQGGVYLVASSVPSEDNKLTVEFTIKDTGIGISPEKCDRLFQPFSQLDSSMTRKYGGTGL 360 N+GGVYLV S +E+N+LT+EFT+KDTGIGIS +K DRLF+PFSQLDSSMTR+YGGTGL Sbjct: 301 NEGGVYLVVSLAKAEENRLTLEFTVKDTGIGISSKKLDRLFKPFSQLDSSMTRRYGGTGL 360 Query: 361 GLAICKSLVGMMGGEIRVESMEEKGATFVFTIKTAVPEDELGKNLQEEEHPGGISGQQWR 420 GLAICKSLV MMGGEI V+S E +GATFVFTI E+E + L+EEEH R Sbjct: 361 GLAICKSLVQMMGGEIEVDSKEGEGATFVFTICVHTHEEEHPR-LREEEHSDKYRVHGGR 419 Query: 421 K-KVLVVDDHPINQRLMVSMLDKLGYETTVAEDGQQAVERSLH-EDYDFIFMDLQMPVMD 478 + +L+VDDHPIN++LM SML+K+G +AEDG+QAVE + + YD IFMDLQMPVMD Sbjct: 420 QPNILIVDDHPINRKLMESMLEKMGMIADMAEDGRQAVEMAAGPKAYDMIFMDLQMPVMD 479 Query: 479 GLTATSKIRQSSGHNATKAVIIAMTANVMEGVQNRCSAAGMDGYISKPLKMSSVQQIISR 538 GL A IRQ A V+IAMTANVM+G+Q RC AGM+ YISKP+K+S V+ +ISR Sbjct: 480 GLEAARLIRQMKPE-ADAPVLIAMTANVMDGIQKRCFDAGMNEYISKPVKISCVKHLISR 538 Query: 539 Y 539 Y Sbjct: 539 Y 539 >A6EKP0.1 A6EKP0_9SPHI Sensor protein EC=2.7.13.3 Length = 536 Score = 360 bits (925), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 206/548 (37%), Positives = 314/548 (57%), Gaps = 23/548 (4%) Query: 5 EPIHILLVDDRPENLLALEAVLESQHYTLVKANSGEEALRCLLKHEFAVIVLDVQMPGMD 64 E I++L+VDDR EN++ALEA+L+ + ++ + EALR + + A+ ++DVQMP MD Sbjct: 3 EKINVLIVDDRAENIIALEALLDREDIEMITTTNPNEALRLCWEMDIAIALVDVQMPEMD 62 Query: 65 GIETAKLIKAREKTKDIPIIFISANSKEAEHLFAGYSAGAIDYMVKPFIPQILKSKIEGF 124 G E +++K+ +TK+I IIF++A SKE +++ G + GA+DY+ KP P + +K++ F Sbjct: 63 GFELVEILKSNPRTKEILIIFVTAISKETKYVVRGLNTGAVDYLYKPLDPFVTSAKVDSF 122 Query: 125 VDMYLTTXXXXXXXXXXXXXXXXXXRINGELTRXXXXXXXXXXXXTEFLAMMSHEIRTPM 184 + + EL + FLA MSHEIRTP+ Sbjct: 123 IQLVRNEREIKRKNLELEAYQK-------ELIKAKEQAEQGKRIKENFLANMSHEIRTPI 175 Query: 185 NGVVGMIDLLMETELAPEQKEYTEIIRKSADTLITVINDILDFTKMESGKMEMEEQLFEL 244 NG++G+ LL +T L+P+Q+E ++ S+D+L+ VINDILD +K+ESGK ++ ++ Sbjct: 176 NGIIGLASLLKKTTLSPDQEEMIRLLEISSDSLLGVINDILDLSKIESGKFKINRAETDV 235 Query: 245 QTTIQEVFSLFSAEAGKKNLELAYFIDQKLPRLIYGDMARLRQVLINLVANAVKFTNQGG 304 T +V +L A +K L+L D LP LI D RL Q+L+NL+ NA+KFT G Sbjct: 236 IKTCTDVTNLLRIRAMEKKLDLITDYDPALPNLIMADSLRLNQILMNLIGNAIKFTASGS 295 Query: 305 VYLVASSVPSEDNKLTVEFTIKDTGIGISPEKCDRLFQPFSQLDSSMTRKYGGTGLGLAI 364 V L ++ + N + V F++ DTGIGI+ +K D++F+ F Q D T K+GGTGLGL+I Sbjct: 296 VTLKVEALDKKGNNIQVRFSVIDTGIGIAKDKIDKIFETFEQADEQTTIKFGGTGLGLSI 355 Query: 365 CKSLVGMMGGEIRVESMEEKGATFVFT-----IKTAVPEDELGKNLQEEEHPGGISGQQW 419 K+L + GG + V S E G+TF FT IKT PE + N E G++ Sbjct: 356 VKNLAELKGGILEVFSEEGHGSTFCFTNWYEVIKT--PEKMINVNKPVLESFEGVN---- 409 Query: 420 RKKVLVVDDHPINQRLMVSMLDKLGYETTVAEDGQQAVERSLHEDYDFIFMDLQMPVMDG 479 VLV +D+PIN+ L++ +L + G + V E+G++A+E DYD I MD MPVM+G Sbjct: 410 ---VLVAEDNPINKFLIIRVLKEWGVKPDVVENGKEALELLTKNDYDIILMDTFMPVMNG 466 Query: 480 LTATSKIRQSSGHNATKAVIIAMTANVMEGVQNRCSAAGMDGYISKPLKMSSVQQIISRY 539 L A IR+ II +A VME + AG + +SKP ++ + + ISR+ Sbjct: 467 LEAIKLIREGYAPGKEGIPIITFSAAVMESDKQTAIEAGANDVVSKPFEVDVLHEKISRF 526 Query: 540 --ASEDHP 545 AS+ P Sbjct: 527 VKASKGSP 534 >C1Z0E5.1 C1Z0E5_PEDHE Signal transduction histidine kinase, COG0642 Length = 528 Score = 356 bits (914), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 200/541 (36%), Positives = 307/541 (56%), Gaps = 23/541 (4%) Query: 5 EPIHILLVDDRPENLLALEAVLESQHYTLVKANSGEEALRCLLKHEFAVIVLDVQMPGMD 64 E I+IL+VDDRPEN++ALEA+L+ ++ + EALR + + A+ ++DVQMP MD Sbjct: 2 EKINILIVDDRPENIIALEALLQRNDINIISTTNPNEALRLSWEMDIAIAMIDVQMPEMD 61 Query: 65 GIETAKLIKAREKTKDIPIIFISANSKEAEHLFAGYSAGAIDYMVKPFIPQILKSKIEGF 124 G E +++K+ +TK+I IIF++A SKE ++ G S GA+DY+ KP P + +K++ F Sbjct: 62 GFELVEILKSNPRTKEILIIFVTAISKETKYAVKGLSTGAVDYLYKPLDPYVTAAKVDSF 121 Query: 125 VDMYLTTXXXXXXXXXXXXXXXXXXRINGELTRXXXXXXXXXXXXTEFLAMMSHEIRTPM 184 + EL + FLA MSHEIRTP+ Sbjct: 122 IQFIRNQREVKKKNKELEAYQK-------ELIKAKELAETGKRIKDNFLANMSHEIRTPI 174 Query: 185 NGVVGMIDLLMETELAPEQKEYTEIIRKSADTLITVINDILDFTKMESGKMEMEEQLFEL 244 NG++G+ LL +TEL EQ+E ++ S+++L+ VIND+LD +K+ESGK ++ ++ Sbjct: 175 NGIIGIAQLLKKTELTDEQREMVNLLEISSNSLLGVINDVLDLSKIESGKFKINRTATDI 234 Query: 245 QTTIQEVFSLFSAEAGKKNLELAYFIDQKLPRLIYGDMARLRQVLINLVANAVKFTNQGG 304 + V L + +K L+L +D +LP++I D RL Q+L+NL+ NA+KFT+QG Sbjct: 235 IKICESVVDLLRIPSIEKKLDLKLALDSELPKMILADSLRLNQILMNLIGNAIKFTHQGS 294 Query: 305 VYLVASSVPSEDNKLTVEFTIKDTGIGISPEKCDRLFQPFSQLDSSMTRKYGGTGLGLAI 364 V L + + N L + F++ DTGIGI+ E D++F+ F Q D T K+GGTGLGL+I Sbjct: 295 VTLKVEILNRKGNNLQLRFSVADTGIGIAKENIDKIFETFEQADEQTTIKFGGTGLGLSI 354 Query: 365 CKSLVGMMGGEIRVESMEEKGATFVFT-----IKTA-VPEDELGKNLQEEEHPGGISGQQ 418 K+L + GG + V S E G+TF F+ +K A VPE K L+E+ P Sbjct: 355 VKNLAKLKGGTLEVISEENIGSTFSFSNWYEVLKDADVPE----KQLEEKLMPFK----- 405 Query: 419 WRKKVLVVDDHPINQRLMVSMLDKLGYETTVAEDGQQAVERSLHEDYDFIFMDLQMPVMD 478 +LV +D+PIN+ L++ +L + V E+GQQA+++ + YD I MD MPVM+ Sbjct: 406 -NLNILVAEDNPINKFLIIKILQNWEVQLEVVENGQQALDKLREKHYDLILMDTFMPVMN 464 Query: 479 GLTATSKIRQSSGHNATKAVIIAMTANVMEGVQNRCSAAGMDGYISKPLKMSSVQQIISR 538 GL A IR+ II +A V++ + AAG + ISKP + + + + I Sbjct: 465 GLEAIRLIREGYAPGKENIPIITFSAAVLDTDKETAIAAGANDVISKPFEPAVLYKKIQE 524 Query: 539 Y 539 Y Sbjct: 525 Y 525 >B8HP17.1 B8HP17_CYAP4 Sensor protein EC=2.7.13.3 Length = 1433 Score = 337 bits (865), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 171/372 (45%), Positives = 246/372 (66%), Gaps = 17/372 (4%) Query: 171 EFLAMMSHEIRTPMNGVVGMIDLLMETELAPEQKEYTEIIRKSADTLITVINDILDFTKM 230 +FLA MSHEIRTPMN V+GM LL+ T L+PEQ++Y E IR + ++L++VINDILDF+++ Sbjct: 889 DFLATMSHEIRTPMNAVIGMTGLLLNTPLSPEQRQYGETIRNAGESLLSVINDILDFSRI 948 Query: 231 ESGKMEMEEQLFELQTTIQEVFSLFSAEAGKKNLELAYFIDQKLPRLIYGDMARLRQVLI 290 ESG +++EE FEL + EV L + A +K+L L ID +P +I D ARLRQ+L+ Sbjct: 949 ESGHLDLEEHPFELPHCVAEVIDLLANRAVEKSLHLEVQIDPGVPAVIVADSARLRQILV 1008 Query: 291 NLVANAVKFTNQGGVYLVASSVP--SEDNKLTVEFTIKDTGIGISPEKCDRLFQPFSQLD 348 NLVANA+KFT+QG V + SV + + T+EF+++DTGIGI+P++ + LFQPFSQ+D Sbjct: 1009 NLVANALKFTDQGEVMIRVKSVAVSPDGQQQTLEFSVQDTGIGIAPKQLEHLFQPFSQVD 1068 Query: 349 SSMTRKYGGTGLGLAICKSLVGMMGGEIRVESMEEKGATFVFTIKTAVPEDELGKNLQEE 408 SS TR+YGG+GLGL I K L MGG+IRV+S G+TF FT+ V + + Sbjct: 1069 SSSTRRYGGSGLGLVISKRLCERMGGQIRVQSRAGVGSTFSFTLPVRVSLTPIMPRID-- 1126 Query: 409 EHPGGISGQQWRK--------KVLVVDDHPINQRLMVSMLDKLGYETTVAEDGQQAVERS 460 P ++ Q W K+LV +D+ NQ+++ ML +LGY + +GQ+A++ Sbjct: 1127 --PPSLTSQPWDSSFALRYPLKILVAEDNTTNQQVIRLMLQQLGYAADLVANGQEAIQAL 1184 Query: 461 LHEDYDFIFMDLQMPVMDGLTATSKIRQSSGHNATKAVIIAMTANVMEGVQNRCSAAGMD 520 + YD +FMDLQMP+MDGL+AT +IRQS G + II ++AN Q AGM+ Sbjct: 1185 NQQPYDLLFMDLQMPIMDGLSATRQIRQSMGPDPW---IIGLSANAFADTQAEAFVAGMN 1241 Query: 521 GYISKPLKMSSV 532 Y++KPLK+ ++ Sbjct: 1242 DYLTKPLKIETL 1253 Score = 57.4 bits (137), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 35/124 (28%), Positives = 66/124 (53%), Gaps = 2/124 (1%) Query: 1 MGVQEPIHILLVDDRPENLLALEAVLESQHYTLVKANSGEEALRCLLKHEFAVIVLDVQM 60 ++ P+ IL+ +D N + +L+ Y +G+EA++ L + + ++ +D+QM Sbjct: 1139 FALRYPLKILVAEDNTTNQQVIRLMLQQLGYAADLVANGQEAIQALNQQPYDLLFMDLQM 1198 Query: 61 PGMDGIETAKLIKAREKTKDIPIIFISANSKEAEHLFAGYSAGAIDYMVKPFIPQILKSK 120 P MDG+ + I+ + D II +SAN+ A+ + AG DY+ KP + L + Sbjct: 1199 PIMDGLSATRQIR-QSMGPDPWIIGLSANAF-ADTQAEAFVAGMNDYLTKPLKIETLAAA 1256 Query: 121 IEGF 124 ++GF Sbjct: 1257 LQGF 1260 >A3IKI3.1 A3IKI3_9CHRO Sensor protein EC=2.7.13.3 Length = 1191 Score = 331 bits (848), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 169/379 (44%), Positives = 255/379 (67%), Gaps = 11/379 (2%) Query: 170 TEFLAMMSHEIRTPMNGVVGMIDLLMETELAPEQKEYTEIIRKSADTLITVINDILDFTK 229 +EFLA MSHEIRTPMN + G DLL+ ++L P+Q+ + EI++ +++ L+ +INDILDF+K Sbjct: 816 SEFLANMSHEIRTPMNSICGFSDLLLRSQLNPKQRHWIEILQANSNRLLALINDILDFSK 875 Query: 230 MESGKMEMEEQLFELQTTIQEVFSLFSAEAGKKNLELAYFIDQKLPRLIYGDMARLRQVL 289 +E+ K+ + + F L+T +QEV F+ +A +K L+L + I+ +PR + GD RL+QVL Sbjct: 876 IEARKLHLNPREFNLETLLQEVRFSFTPQAERKGLQLTHEIEPDVPRHLIGDDFRLQQVL 935 Query: 290 INLVANAVKFTNQGGVYL-VASSVPSEDNK---LTVEFTIKDTGIGISPEKCDRLFQPFS 345 NLV+NA+KFT G V + V+ +E N + + F+++DTGIGISP+ + LFQPF+ Sbjct: 936 SNLVSNAIKFTETGEVKIAVSQQGETEVNGGIIVPLRFSVQDTGIGISPDAQENLFQPFT 995 Query: 346 QLDSSMTRKYGGTGLGLAICKSLVGMMGGEIRVESMEEKGATFVFTIKTAVPEDELGKNL 405 Q+DSS TR+YGGTGLGL IC+ +V +MGGEI V+S + G+TF FT+ P+ Sbjct: 996 QVDSSATRRYGGTGLGLTICRRIVQLMGGEIHVDSEVDVGSTFWFTVPLQQPDHPASP-- 1053 Query: 406 QEEEHP-GGISGQQWRK--KVLVVDDHPINQRLMVSMLDKLGYETTVAEDGQQAVERSLH 462 EHP +S + + K+LVV+D P N+ L++ ML + ET E+GQ+A+ER L Sbjct: 1054 ATSEHPETSVSPLELQSTCKILVVEDQPDNRILLLLMLQEFDCETDWVENGQEALERILA 1113 Query: 463 EDYDFIFMDLQMPVMDGLTATSKIRQSSGHNATKAVIIAMTANVMEGVQNRCSAAGMDGY 522 EDYD +FMD QMPVMDG AT +R+ + + +II +TAN M + +C AGMD Y Sbjct: 1114 EDYDLVFMDCQMPVMDGYEATRLLREQETED--RVIIIGLTANAMTRDREKCLNAGMDDY 1171 Query: 523 ISKPLKMSSVQQIISRYAS 541 +SKP+ + ++QI++++ + Sbjct: 1172 LSKPVLIEDIEQILNKWTA 1190 Score = 60.8 bits (146), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 35/115 (30%), Positives = 65/115 (56%), Gaps = 5/115 (4%) Query: 1 MGVQEPIHILLVDDRPENLLALEAVLESQHYTLVKANSGEEALRCLLKHEFAVIVLDVQM 60 + +Q IL+V+D+P+N + L +L+ +G+EAL +L ++ ++ +D QM Sbjct: 1066 LELQSTCKILVVEDQPDNRILLLLMLQEFDCETDWVENGQEALERILAEDYDLVFMDCQM 1125 Query: 61 PGMDGIETAKLIKAREKTKDIPIIFISAN--SKEAEHLFAGYSAGAIDYMVKPFI 113 P MDG E +L++ +E + II ++AN +++ E +AG DY+ KP + Sbjct: 1126 PVMDGYEATRLLREQETEDRVIIIGLTANAMTRDREKCL---NAGMDDYLSKPVL 1177 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.134 0.370 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,862,658,328 Number of extensions: 111146528 Number of successful extensions: 555526 Number of sequences better than 1.0e-05: 46331 Number of HSP's gapped: 489926 Number of HSP's successfully gapped: 54387 Length of query: 556 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 415 Effective length of database: 1,732,333,088 Effective search space: 718918231520 Effective search space used: 718918231520 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 134 (56.2 bits)