BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0167.0008.p (517 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KDQ8.1 B3KDQ8_9BACI Response regulator receiver 412 e-113 B1D7X3.1 B1D7X3_9BACL Two component transcriptional regulator, A... 359 4e-97 Q9KBL6.1 Q9KBL6_BACHD Two-component response regulator 297 2e-78 Q5WIY3.1 Q5WIY3_BACSK Two-component response regulator 296 4e-78 A7VW45.1 A7VW45_9CLOT Putative uncharacterized protein 243 5e-62 >B3KDQ8.1 B3KDQ8_9BACI Response regulator receiver Length = 518 Score = 412 bits (1058), Expect = e-113, Method: Compositional matrix adjust. Identities = 235/528 (44%), Positives = 326/528 (61%), Gaps = 28/528 (5%) Query: 2 MIKVLIVDDEPKLREGLRALIPWGQLGFTVVATAANGLQALEKYHIHDPELIVVDIRMPG 61 M+KVLIVDDEPKLREGL++++PW +LG+ VV TAANG +ALEK+ +DP+L+++DIRMPG Sbjct: 1 MMKVLIVDDEPKLREGLKSIVPWTELGYQVVDTAANGNEALEKHGKYDPDLMLIDIRMPG 60 Query: 62 MDGLELIGELRNEGSTSHVLILSGHADFDYAKRAIGYRIDGYLLKPVDEEEMISLLKELR 121 MDGL+LI +RN + H+LILSG+ADFDYAKRAI +R+DGYLLKPVDE+E+ L +++ Sbjct: 61 MDGLQLIEAIRNLDAEIHLLILSGYADFDYAKRAISHRVDGYLLKPVDEDELSKYLLQIK 120 Query: 122 ETIDREDRFSRWNEEEPTRNRESLLRALLQPPAEESGADDPG--KQAAALGLTPGRVEVV 179 E I++E N +RE ++ P ES D A GL +V+ Sbjct: 121 EAIEQEQERKALNRAASEMSREQFIQTWFNP---ESKPDSAALRHMAERSGLLWNHYQVL 177 Query: 180 LIELLAPAHXXXXXXXXXXXXXXQHFSGSGDRLFFTLPPYIGLLLKEP-LQDGMRRE--R 236 L + F +G F+L +G+L+ P L G R+E + Sbjct: 178 LFHHNGSDESGEETDDRLKNQLIEAFEENGRGAVFSLHGQLGILMPTPVLTAGGRKELLQ 237 Query: 237 LIEELAGLICPCGFNFTAAAGGAVPRPEEAAESFNAARDLLRRAFFYRKGMMLTADPSGM 296 L+EE A G TA+ G V R E+ A+S+ A++ +R FFY P M Sbjct: 238 LVEEAA---SRAGTAITASLGRQVHRLEDVADSYRCAKERIRERFFYA--------PGEM 286 Query: 297 LFPDS-----GEADTE-QVTDAES---RLLLAVETGSRAAIEPLVQAISAGLIAAGGEEQ 347 LFP+S G D E Q D E +L AV+ G+ + L+ ++ ++ E+ Sbjct: 287 LFPESERFAGGNTDEERQPYDPEQLMEQLYYAVDVGNVEVQQKLLYTAASAMVKEEYTEE 346 Query: 348 QIKDTFVRILSTVLARLEPVYPEIRNNTVKHFPPIGELYQSHYLEDLQEQSVAFLAEIAG 407 ++K FV +L+ V +L + E+++ T ++ I +++ DL S FL E+ Sbjct: 347 RMKRAFVELLTGVHNKLMQHHTELQSRTKEYSDRIAAIFRQRTAYDLCRHSSQFLEELIW 406 Query: 408 QMTSGVKGNEIKKITELIQRRYNENLKLETLSELFSYNSAYLGKMFKNTTGEYFNTYLDK 467 Q +G + E+K+I +LIQR YNEN+KLETL+ +F+YNSAYLGKMFKNTTGEYFNTYLDK Sbjct: 407 QAGNGGRDQEMKRIMDLIQRNYNENIKLETLASIFNYNSAYLGKMFKNTTGEYFNTYLDK 466 Query: 468 VRIEKAKEFLAQGMKVYEVAEKVGYMNSDYFNAKFRKYVGTSPSSFRK 515 VRI+KAK+FL QGMKVY+VAEKVGY N DYF++KF+KYVGTSPS+FRK Sbjct: 467 VRIDKAKDFLKQGMKVYQVAEKVGYTNVDYFHSKFKKYVGTSPSNFRK 514 >B1D7X3.1 B1D7X3_9BACL Two component transcriptional regulator, AraC family Length = 507 Score = 359 bits (921), Expect = 4e-97, Method: Compositional matrix adjust. Identities = 210/518 (40%), Positives = 296/518 (57%), Gaps = 18/518 (3%) Query: 2 MIKVLIVDDEPKLREGLRALIPWGQLGFTVVATAANGLQALEKYHIHDPELIVVDIRMPG 61 M KVL+VDDEP +REGLR L+ W LG+ VV TAANG AL+K HD +LI+VDIRMP Sbjct: 1 MYKVLLVDDEPMIREGLRTLLEWESLGYEVVDTAANGKDALQKCEQHDLDLIIVDIRMPE 60 Query: 62 MDGLELIGELRNEGSTSHVLILSGHADFDYAKRAIGYRIDGYLLKPVDEEEMISLLKELR 121 M+GLELI ++R G T HVLILSG+ADF+YAK+AI RIDGYLLKPVDE+E++ L LR Sbjct: 61 MNGLELIKKIRENGGTMHVLILSGYADFEYAKQAIVQRIDGYLLKPVDEDELMEYLHSLR 120 Query: 122 ETIDREDRFSRWNEEEPTRNRESLLRALLQPPAEESGADDPGKQAAALGLTPGRVEVVLI 181 + +D E + +E N E L+ LL G+ + E++LI Sbjct: 121 KELDLEYETRQKRLDERQGNAEDDLKRLLV-----EGSTGSSLSPLSASPDWKEFELLLI 175 Query: 182 ELLAPAHXXXXXXXXXXXXXXQHFSGSGDRLFFTLPPYIGLLLKEPLQDGMRRERLIEEL 241 + + SG L + PY+ +LL + G+ ER ++ Sbjct: 176 KTHERNEEETAGHAQIKRRLSERLDQSGGGLAIAMEPYLLVLLNK----GLDNERFRRDM 231 Query: 242 AGLIC-PC---GFNFTAAAGGAVPRPEEAAESFNAARDLLRRAFFYRKGMMLTADPSGML 297 +I C +FT +GG + ++ A + ++ FF + G + DP Sbjct: 232 HAMIADACEGLASDFTVVSGGNASGNADIQAAYQKALERMKNRFFLKGGQITAEDPQ--- 288 Query: 298 FPDSGEADTEQVTDAESRLLLAVETGSRAAIEPLVQAISAGLIAAGGEEQQIKDTFVRIL 357 P E +T +L LA+E +R AI ++ + + A G E ++K FV ++ Sbjct: 289 MPAGSEDAKPDLTGTAEKLYLALEIVNREAIRQQIEESAEAMKAIGFGEAEMKAAFVELV 348 Query: 358 STVLARLEPVYPEIRNNTVKHFPPIGELYQSHYLEDLQEQSVAFLAEIAGQMTSGVKGNE 417 S VL +L PE++ + P EL++ + + L + A + +IA + + + Sbjct: 349 SAVLDKLASKRPELQVRDYRQRIP--ELFREYRISSLTRLATAIIDQIADSLDNSSADKQ 406 Query: 418 IKKITELIQRRYNENLKLETLSELFSYNSAYLGKMFKNTTGEYFNTYLDKVRIEKAKEFL 477 IK++ +LI R Y ENLK+ETL+ELF+YNSAYLGK+FK TGE FNTYLDKVR+E+AK L Sbjct: 407 IKRMIDLIHRNYKENLKMETLAELFNYNSAYLGKLFKQVTGENFNTYLDKVRMEQAKILL 466 Query: 478 AQGMKVYEVAEKVGYMNSDYFNAKFRKYVGTSPSSFRK 515 QG+KVY+VAE VGY N DYF++KFRKYVG+SPS +RK Sbjct: 467 EQGLKVYQVAEMVGYANVDYFHSKFRKYVGSSPSVYRK 504 >Q9KBL6.1 Q9KBL6_BACHD Two-component response regulator Length = 506 Score = 297 bits (761), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 187/522 (35%), Positives = 270/522 (51%), Gaps = 34/522 (6%) Query: 2 MIKVLIVDDEPKLREGLRALIPWGQLGFTVVATAANGLQALEKYHIHDPELIVVDIRMPG 61 M V+IVDDE +REGL+ALI W + GF V+ TA NG + KY P+L++VDIRMP Sbjct: 1 MYDVMIVDDEAMVREGLKALISWEEYGFRVIDTARNGKEGFTKYRQLSPDLMIVDIRMPE 60 Query: 62 MDGLELIGELRNEGSTSHVLILSGHADFDYAKRAIGYRIDGYLLKPVDEEEMISLLKELR 121 +DGL LI +R E S H +ILSGH+DF+YAK+A+G + D YLLKP+DE+E+I LK++ Sbjct: 61 VDGLSLIESIRAEDSAIHFIILSGHSDFNYAKKALGCQCDDYLLKPLDEDELIDSLKKVY 120 Query: 122 ETIDREDRFSRWNEEEPTRNRESLLRALLQ-------PPAEESGADDPGKQAAALGLTPG 174 I R + E + E +L LL+ P +E Q A + Sbjct: 121 GRITRHHQVHELVERVQEKQVEMVLTELLEGTPLSEIPIGKEHNFFATDYQVALVENRQD 180 Query: 175 RVEVVLIELLAPAHXXXXXXXXXXXXXXQHFSGSGDRLFFTLPPYIGLLLKEPLQDGMRR 234 R+ L L+ + P YI ++ K + Sbjct: 181 RLTKQLKRLIEE---------------------QEEGYVIPFPEYIVIVCKNRFLQKRGK 219 Query: 235 ERLIEELAGLICPCGFNFTAAAGGAVPRPEEAAESFNAARDLLRRAFFYRKGMMLTADP- 293 + A + + A AG V + ES+ +A+ L + FF KG + TAD Sbjct: 220 DHRYHLFAKWLEEEELH--ACAGSKVVNLADIYESYQSAKRLYEKKFFVEKGRLFTADQL 277 Query: 294 SGMLFPDSGEADTEQVTDAESRLLLAVETGSRAAIEPLVQAISAGLIAAGGEEQQIKDTF 353 P++ E E D RL +++ G+ +++ + +I EE++IK Sbjct: 278 VDRSKPEAPEFSLESYAD---RLYYSIDIGNMEGCVAIIEELKNVVIVHLQEEKEIKVAL 334 Query: 354 VRILSTVLARLEPVYPEIRNNTVKHFPPIGELYQSHYLEDLQEQSVAFLAEIAGQMTSGV 413 ++ S +L +L +P + G++YQ +L + L + M +G Sbjct: 335 FQLYSNILHQLVRSHPNMEGVLEPLVMNAGDIYQFEHLPGIMAFLTKQLKYVIDCMDNGQ 394 Query: 414 KGNEIKKITELIQRRYNENLKLETLSELFSYNSAYLGKMFKNTTGEYFNTYLDKVRIEKA 473 ++K+ LI + Y +NL+LETL+ +F+YN AYLGK+FKN TGEYFNTYLDKVRIE Sbjct: 395 PDLLLRKMIALIHKDYAKNLRLETLASVFNYNRAYLGKLFKNYTGEYFNTYLDKVRIENG 454 Query: 474 KEFLAQGMKVYEVAEKVGYMNSDYFNAKFRKYVGTSPSSFRK 515 K L +G KVYEVAEK+GY N DYF+ KF+KYVG SPS+FRK Sbjct: 455 KRLLQKGYKVYEVAEKIGYANVDYFHRKFKKYVGVSPSTFRK 496 >Q5WIY3.1 Q5WIY3_BACSK Two-component response regulator Length = 493 Score = 296 bits (757), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 191/522 (36%), Positives = 274/522 (52%), Gaps = 37/522 (7%) Query: 2 MIKVLIVDDEPKLREGLRALIPWGQLGFTVVATAANGLQALEKYHIHDPELIVVDIRMPG 61 M KVLI DDE +REG++ LIPW GF V + A NG ALEKY P+L++ DIRMP Sbjct: 1 MYKVLIADDEWMIREGVKNLIPWEHYGFEVASLACNGKDALEKYKHDKPDLVIADIRMPQ 60 Query: 62 MDGLELIGELRNEGSTSHVLILSGHADFDYAKRAIGYRIDGYLLKPVDEEEMISLLKELR 121 MDGL L+ E+R E L+LSGHADF YA+ AIG+ +DGYLLKP++E+E+I L+ + Sbjct: 61 MDGLSLLKEIRTENEAVPFLLLSGHADFHYAQEAIGHGVDGYLLKPLEEDELIEHLQIVF 120 Query: 122 ETIDREDRFSRWNEEEPTRNRESLLRALLQPPAEESGADDPGKQAAALGLTPGRVEVVLI 181 +++ + ++ +E LL LL + D + LGL R ++ L+ Sbjct: 121 HKLEQRKQAHVLRQQSVRIEQERLLLNLLAGKPLPTSVD-----FSRLGLAASRYQIFLV 175 Query: 182 ELLAPAHXXXXXXXXXXXXXXQH----FSGSGDRLFFTLPPYIGLLLKEPLQDGMRRERL 237 H H F+ GD GLL+ LQ+G+ + L Sbjct: 176 ------HAGERDALEHLAEQIPHTAVPFAKGGD---------AGLLICH-LQEGLTKSEL 219 Query: 238 IEELAGLICPCGFNFTAAAGGAVPRPEEAAESFNAARDLLRRAFFYRKGMMLTADPSGML 297 + + L+ P A G V + S+ AA+ LL AF+ KG +++ P+ + Sbjct: 220 QQWASHLLAPMRH---GALGKCVRKLSAIQVSYTAAKKLLSLAFYADKGSVISELPTVL- 275 Query: 298 FPDSGEADTEQVTDAESRLLLAVETGSRAAIEPLVQAIS---AGLIAAGGEEQQIKDTFV 354 G+ + ++ E R+ LA+ G + EP QA+S A + A +E +K Sbjct: 276 --QDGQLAKKPLSFYEERIYLALHIGEK---EPAKQAVSDFLADVAARRMKEASLKAKAS 330 Query: 355 RILSTVLARLEPVYPEIRNNTVKHFPPIGELYQSHYLEDLQEQSVAFLAEIAGQMTSGVK 414 + V+ RL + + K + +L ++ L+ E+A Sbjct: 331 ELALNVIQRLIASHVLAKEWAQKGYRFTAQLQEAEDFLQLRHVLRCLCDELAANTNVRSN 390 Query: 415 GNEIKKITELIQRRYNENLKLETLSELFSYNSAYLGKMFKNTTGEYFNTYLDKVRIEKAK 474 +KK+ ++I RY+ENL+LET+S + +YNSAYLGK FK TG+YFNTYLDKVRI K+K Sbjct: 391 DTAVKKMIDMIDSRYDENLRLETISAVLNYNSAYLGKRFKQETGDYFNTYLDKVRIHKSK 450 Query: 475 EFLAQGMKVYEVAEKVGYMNSDYFNAKFRKYVGTSPSSFRKN 516 E L G KVYE AEKVGY N DYF+ KF+KY G SPS+FRK Sbjct: 451 ELLRAGCKVYEAAEKVGYPNVDYFHRKFKKYTGMSPSAFRKK 492 >A7VW45.1 A7VW45_9CLOT Putative uncharacterized protein Length = 528 Score = 243 bits (619), Expect = 5e-62, Method: Compositional matrix adjust. Identities = 156/522 (29%), Positives = 271/522 (51%), Gaps = 16/522 (3%) Query: 2 MIKVLIVDDEPKLREGLRALIPWGQLGFTVVATAANGLQALEKYHIHDPELIVVDIRMPG 61 ++KV+IVDDE +R GLRA++ W + G+TV AA+G +K ++ P+LI+ DI+MP Sbjct: 13 LLKVMIVDDEEMIRRGLRAIVDWKEYGYTVCCDAADGEDGYQKALVYQPDLIITDIKMPI 72 Query: 62 MDGLELIGELRNEGSTSHVLILSGHADFDYAKRAIGYRIDGYLLKPVDEEEMISLLKELR 121 DGL+++ +LR + ++L+G+A+F+YA++A+ Y+LKP+DEEE++ L E R Sbjct: 73 ADGLQMMTKLRENCFETEFILLTGYAEFEYAQKALQLGAKSYILKPIDEEELVKTLIEAR 132 Query: 122 ETIDREDRFSRWNEEEPTRNRESLLRALLQPPAEESGADDPGKQAAALGLTPGRVEVVLI 181 E I + R ++ + + + E ++ L+ +E D L R ++VL+ Sbjct: 133 EEI-LQRRKENFHNKYFSISMEQVITKLVYGAVDEEFID-AANAVYGFQLPWKRYQLVLL 190 Query: 182 ELLAPAHXXXXXXXXXXXXXXQHFSGSGDRLFFTLPPYIGLLLKEPL-QDGMRRERLIEE 240 E + F+ + F+L + +L K+ + + G + RL+E+ Sbjct: 191 E-----QTKNQETDEKVLDLLKDFTKNNIGFVFSLNNHFVVLTKDVIFEQG--KMRLLED 243 Query: 241 LAGLICPC-GFNFTAAAGGAVPRPEEAAESFNAARDLLRRAFFYRKGMMLTADPSGMLFP 299 L G + G+ + E+ +++ AA + F + ++ D G + Sbjct: 244 LNGKLRKLPGYTQPMVVSRPLKELEQINQAYYAASYFIEHQFIFPYEEIVLIDEVGNPYA 303 Query: 300 DSGEADTEQVTDAESR-----LLLAVETGSRAAIEPLVQAISAGLIAAGGEEQQIKDTFV 354 ++ Q + R L +AV I L++ + + +G + +QI+ +V Sbjct: 304 QGKISNANQREQLDYRKIAEGLCVAVCGNDLTGISSLLENLGNKCVESGYDLEQIRIRYV 363 Query: 355 RILSTVLARLEPVYPEIRNNTVKHFPPIGELYQSHYLEDLQEQSVAFLAEIAGQMTSGVK 414 +V+ L+ EI I ++ + +L+ + + L++IA ++ S + Sbjct: 364 STYVSVMYLLKIQSEEIFKQEGMVDVVILQISRLSHLQSINSFFLDKLSQIAQKLNSNQQ 423 Query: 415 GNEIKKITELIQRRYNENLKLETLSELFSYNSAYLGKMFKNTTGEYFNTYLDKVRIEKAK 474 GN I+K+ E I+ YN +L L+ LS++F YN AY GK+FK+ TG +N Y+ VR+EKAK Sbjct: 424 GNVIRKMKEYIEANYNSDLTLKNLSKIFHYNVAYFGKLFKSNTGMSYNDYVTSVRMEKAK 483 Query: 475 EFLAQGMKVYEVAEKVGYMNSDYFNAKFRKYVGTSPSSFRKN 516 E L QG KVY+VA +VGY + DYFN KF+KY PS F K+ Sbjct: 484 ELLNQGEKVYKVANQVGYQDLDYFNMKFKKYFNALPSDFHKD 525 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.137 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,003,439,389 Number of extensions: 126969450 Number of successful extensions: 523140 Number of sequences better than 1.0e-05: 12977 Number of HSP's gapped: 537055 Number of HSP's successfully gapped: 13614 Length of query: 517 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 377 Effective length of database: 1,741,754,103 Effective search space: 656641296831 Effective search space used: 656641296831 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 134 (56.2 bits)