BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0155.0005.p (447 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A7Z1Y5.1 A7Z1Y5_BACA2 YycB 343 2e-92 B1KVD2.1 B1KVD2_CLOBM Transporter, major facilitator family 338 5e-91 C1FQD5.1 C1FQD5_CLOBJ Inner membrane transport protein YeaN 337 2e-90 B1QBY8.1 B1QBY8_CLOBO Inner membrane transport protein YeaN 337 2e-90 A7GF62.1 A7GF62_CLOBL Transporter, major facilitator family 337 2e-90 >A7Z1Y5.1 A7Z1Y5_BACA2 YycB Length = 404 Score = 343 bits (879), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 185/365 (50%), Positives = 226/365 (61%), Gaps = 12/365 (3%) Query: 34 LLVVGIIFVAAALRAPFTSVGPLLGMIRDDLGLSNTLAGAITTXXXXXXXXXXXXXXXXX 93 LLV+G+I + A LRAP TSVGPL+ IRD LG++N AG ITT Sbjct: 20 LLVIGVILIGANLRAPLTSVGPLVSSIRDSLGMTNAAAGTITTVPLLAFACLSPFVPLLS 79 Query: 94 RRFGTAXXXXNVXXXXXXXXXXXXXXRSGSGTVMLFAGTAMIGLSIAVCNVLLPGLIKGK 153 RRFGT V RS +G LF GT ++GLSIAVCNVLLP LIK K Sbjct: 80 RRFGTEI----VLLSSLIVLTAGTLLRSIAGIGTLFFGTILLGLSIAVCNVLLPSLIKHK 135 Query: 154 FPERIGLMTGVYTVSMNICAAAASGISVPLAQHAGFGWRGTLALWFAVASLATIFWIPQM 213 FP +G+MTGVY+VSMN+C A ASGISVP+A AG GW+G L W ++ +A + WIPQM Sbjct: 136 FPGNLGIMTGVYSVSMNLCGAIASGISVPIASSAGLGWKGALGCWAILSFIAFVMWIPQM 195 Query: 214 RN-----MTKGNTADHKQSSIRIWRSPLAWQVTLFMGLQSLLYYVLIAWFSVILSERGMS 268 R T G + K S + RSPLAW+VT+FMGLQSL++Y +IAW IL + G+S Sbjct: 196 RGRELPVRTTGTNGEKKSS---LLRSPLAWKVTMFMGLQSLIFYTVIAWLPEILQQNGLS 252 Query: 269 SSHAGWILSLMQLAQLPFTFFVPLWAGRMKNQRSLVVITSILFMIGILGVWLGSTAWMAV 328 SS AGW+LSLMQ + LP TF VP+ A +MKNQR+L +T++ F+IGI GV GS A + Sbjct: 253 SSKAGWMLSLMQFSVLPITFIVPIAAAKMKNQRALAGLTALFFLIGIAGVLFGSPALTPL 312 Query: 329 WXXXXXXXXXXXXXXXXXXXSLRTRSTQEASELSGMAQSVGYLLAAMGPALFGLLHDVNH 388 W SLRTR EA+ LSGMAQS GYLLAA GP +FGLLHD+ H Sbjct: 313 WVILIGIAGGCAFSLAMMFFSLRTRHVHEAAALSGMAQSFGYLLAAFGPLVFGLLHDITH 372 Query: 389 SWNVP 393 W VP Sbjct: 373 GWTVP 377 >B1KVD2.1 B1KVD2_CLOBM Transporter, major facilitator family Length = 414 Score = 338 bits (868), Expect = 5e-91, Method: Compositional matrix adjust. Identities = 185/397 (46%), Positives = 247/397 (62%), Gaps = 20/397 (5%) Query: 1 MCCNREDIMKSKQQTAVTLELDKTRPDTGANRFLLVVGIIFVAAALRAPFTSVGPLLGMI 60 M N+ D K+Q + ++ K+ +L++GIIF+AA LRAP TSVGPL+ I Sbjct: 2 MSLNKSD----KKQNNMDFKVRKSA------SLMLIIGIIFIAANLRAPLTSVGPLVKFI 51 Query: 61 RDDLGLSNTLAGAITTXXXXXXXXXXXXXXXXXRRFGTAXXXXNVXXXXXXXXXXXXXXR 120 RD+L +SNTLAG ITT R+FG V R Sbjct: 52 RDNLHISNTLAGMITTLPLFAFALFSPVAPRLGRKFGVEL----VLLLSVIFLTVGIILR 107 Query: 121 SGSGTVMLFAGTAMIGLSIAVCNVLLPGLIKGKFPERIGLMTGVYTVSMNICAAAASGIS 180 S SG LF GTA+IGL+I+V NVL+P LIK FPE+IG+MTGVY++SMN A ASGIS Sbjct: 108 SLSGVAGLFIGTAIIGLAISVANVLIPSLIKRDFPEKIGVMTGVYSISMNTFGAIASGIS 167 Query: 181 VPLAQHAGFGWRGTLALWFAVASLATIFWIPQMR----NMTKGNTADHKQSSIRIWRSPL 236 +P+A GF W G L +W ++ ++ I W+PQ++ +KG+ AD S++ +W+S L Sbjct: 168 IPIATGLGFKWSGALGIWGILSFISIILWLPQVKRNDGEASKGHKAD--SSNVSLWKSSL 225 Query: 237 AWQVTLFMGLQSLLYYVLIAWFSVILSERGMSSSHAGWILSLMQLAQLPFTFFVPLWAGR 296 AWQVTLFMGLQSL++Y ++AW IL ++GMSS+ AGW+LSLMQLA +PFTF V + AGR Sbjct: 226 AWQVTLFMGLQSLVFYSMVAWMPEILMQKGMSSNKAGWMLSLMQLALIPFTFIVSVLAGR 285 Query: 297 MKNQRSLVVITSILFMIGILGVWLGSTAWMAVWXXXXXXXXXXXXXXXXXXXSLRTRSTQ 356 NQRSLV+ + +IGILG+ GS+ ++ +W SLRT ++ Sbjct: 286 RSNQRSLVISGCLFILIGILGLLYGSSQFVFLWIIILGIGGGFAFSLSMMFFSLRTENSN 345 Query: 357 EASELSGMAQSVGYLLAAMGPALFGLLHDVNHSWNVP 393 EA++LSGMAQS+GYLLAA GP LFG LHD +SW VP Sbjct: 346 EAAQLSGMAQSLGYLLAAFGPILFGFLHDATNSWKVP 382 >C1FQD5.1 C1FQD5_CLOBJ Inner membrane transport protein YeaN Length = 414 Score = 337 bits (864), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 185/397 (46%), Positives = 245/397 (61%), Gaps = 20/397 (5%) Query: 1 MCCNREDIMKSKQQTAVTLELDKTRPDTGANRFLLVVGIIFVAAALRAPFTSVGPLLGMI 60 M N+ D K+Q + ++ K+ +L++GIIF+AA LRAP TSVGPL+ I Sbjct: 2 MSLNKSD----KKQNNMDFKVRKSA------SLMLIIGIIFIAANLRAPLTSVGPLVKFI 51 Query: 61 RDDLGLSNTLAGAITTXXXXXXXXXXXXXXXXXRRFGTAXXXXNVXXXXXXXXXXXXXXR 120 RD+L +SNTLAG ITT R+FG V R Sbjct: 52 RDNLHISNTLAGMITTLPLFAFAIFSPVAPRLGRKFGVEL----VLLLSVIFLTVGIILR 107 Query: 121 SGSGTVMLFAGTAMIGLSIAVCNVLLPGLIKGKFPERIGLMTGVYTVSMNICAAAASGIS 180 S SG LF GTA+IGL+I+V NVL+P LIK FPE+IG+MTGVY++SMN A ASGIS Sbjct: 108 SLSGVAGLFIGTAIIGLAISVANVLIPSLIKRDFPEKIGVMTGVYSISMNTFGAIASGIS 167 Query: 181 VPLAQHAGFGWRGTLALWFAVASLATIFWIPQMR----NMTKGNTADHKQSSIRIWRSPL 236 VP+A G W G L +W ++ ++ I W+PQ++ +KG+ AD S++ +W+S L Sbjct: 168 VPIATRLGLKWSGALGIWGILSFISIILWLPQVKRNDGEASKGHKAD--SSNVSLWKSSL 225 Query: 237 AWQVTLFMGLQSLLYYVLIAWFSVILSERGMSSSHAGWILSLMQLAQLPFTFFVPLWAGR 296 AWQVTLFMGLQSL++Y ++AW IL ++GMSS+ AGW+LSLMQLA +PFTF V + AGR Sbjct: 226 AWQVTLFMGLQSLVFYSMVAWMPEILMQKGMSSNKAGWMLSLMQLALIPFTFIVSVLAGR 285 Query: 297 MKNQRSLVVITSILFMIGILGVWLGSTAWMAVWXXXXXXXXXXXXXXXXXXXSLRTRSTQ 356 NQRSLV+ + +IGILG+ GS+ ++ +W SLRT + Sbjct: 286 RSNQRSLVISGCLFILIGILGLLYGSSQFVFLWIIILGIGGGFAFSLSMMFFSLRTEDSN 345 Query: 357 EASELSGMAQSVGYLLAAMGPALFGLLHDVNHSWNVP 393 EA++LSGMAQS+GYLLAA GP LFG LHD +SW VP Sbjct: 346 EAAQLSGMAQSLGYLLAAFGPILFGFLHDATNSWKVP 382 >B1QBY8.1 B1QBY8_CLOBO Inner membrane transport protein YeaN Length = 414 Score = 337 bits (864), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 185/397 (46%), Positives = 245/397 (61%), Gaps = 20/397 (5%) Query: 1 MCCNREDIMKSKQQTAVTLELDKTRPDTGANRFLLVVGIIFVAAALRAPFTSVGPLLGMI 60 M N+ D K+Q + ++ K+ +L++GIIF+AA LRAP TSVGPL+ I Sbjct: 2 MSLNKSD----KKQNNMDFKVRKSA------SLMLIIGIIFIAANLRAPLTSVGPLVKFI 51 Query: 61 RDDLGLSNTLAGAITTXXXXXXXXXXXXXXXXXRRFGTAXXXXNVXXXXXXXXXXXXXXR 120 RD+L +SNTLAG ITT R+FG V R Sbjct: 52 RDNLHISNTLAGMITTLPLFAFAIFSPVAPRLGRKFGVEL----VLLLSVIFLTVGIILR 107 Query: 121 SGSGTVMLFAGTAMIGLSIAVCNVLLPGLIKGKFPERIGLMTGVYTVSMNICAAAASGIS 180 S SG LF GTA+IGL+I+V NVL+P LIK FPE+IG+MTGVY++SMN A ASGIS Sbjct: 108 SLSGVAGLFIGTAIIGLAISVANVLIPSLIKRDFPEKIGVMTGVYSISMNTFGAIASGIS 167 Query: 181 VPLAQHAGFGWRGTLALWFAVASLATIFWIPQMR----NMTKGNTADHKQSSIRIWRSPL 236 VP+A G W G L +W ++ ++ I W+PQ++ +KG+ AD S++ +W+S L Sbjct: 168 VPIATRLGLKWSGALGIWGILSFISIILWLPQVKRNDGEASKGHKAD--SSNVSLWKSSL 225 Query: 237 AWQVTLFMGLQSLLYYVLIAWFSVILSERGMSSSHAGWILSLMQLAQLPFTFFVPLWAGR 296 AWQVTLFMGLQSL++Y ++AW IL ++GMSS+ AGW+LSLMQLA +PFTF V + AGR Sbjct: 226 AWQVTLFMGLQSLVFYSMVAWMPEILMQKGMSSNKAGWMLSLMQLALIPFTFIVSVLAGR 285 Query: 297 MKNQRSLVVITSILFMIGILGVWLGSTAWMAVWXXXXXXXXXXXXXXXXXXXSLRTRSTQ 356 NQRSLV+ + +IGILG+ GS+ ++ +W SLRT + Sbjct: 286 RSNQRSLVISGCLFILIGILGLLYGSSQFVFLWIIILGIGGGFAFSLSMMFFSLRTEDSN 345 Query: 357 EASELSGMAQSVGYLLAAMGPALFGLLHDVNHSWNVP 393 EA++LSGMAQS+GYLLAA GP LFG LHD +SW VP Sbjct: 346 EAAQLSGMAQSLGYLLAAFGPILFGFLHDATNSWKVP 382 >A7GF62.1 A7GF62_CLOBL Transporter, major facilitator family Length = 414 Score = 337 bits (863), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 185/397 (46%), Positives = 246/397 (61%), Gaps = 20/397 (5%) Query: 1 MCCNREDIMKSKQQTAVTLELDKTRPDTGANRFLLVVGIIFVAAALRAPFTSVGPLLGMI 60 M N+ D K+Q + ++ K+ +L++GIIF+AA LRAP TSVGPL+ I Sbjct: 2 MSLNKSD----KKQNNIDFKVRKSA------SLMLIIGIIFIAANLRAPLTSVGPLVKFI 51 Query: 61 RDDLGLSNTLAGAITTXXXXXXXXXXXXXXXXXRRFGTAXXXXNVXXXXXXXXXXXXXXR 120 RD+L +SNTLAG ITT R+FG V R Sbjct: 52 RDNLHISNTLAGMITTLPLFAFAIFSPVAPRLGRKFGVEL----VLLLSVIFLTVGIILR 107 Query: 121 SGSGTVMLFAGTAMIGLSIAVCNVLLPGLIKGKFPERIGLMTGVYTVSMNICAAAASGIS 180 S SG LF GTA+IGL+I+V NVL+P LIK FPE+IG+MTGVY++SMN A ASGIS Sbjct: 108 SLSGVAGLFIGTAIIGLAISVANVLIPSLIKRDFPEKIGVMTGVYSISMNTFGAIASGIS 167 Query: 181 VPLAQHAGFGWRGTLALWFAVASLATIFWIPQMR----NMTKGNTADHKQSSIRIWRSPL 236 +P+A GF W G L +W ++ ++ I W+PQ++ +KG+ AD S++ +W+S L Sbjct: 168 IPIATGLGFKWSGALGIWGILSFISIILWLPQVKRNDGEASKGHKAD--SSNVSLWKSSL 225 Query: 237 AWQVTLFMGLQSLLYYVLIAWFSVILSERGMSSSHAGWILSLMQLAQLPFTFFVPLWAGR 296 AWQVTLFMGLQSL++Y ++AW IL ++GMSS+ AGW+LSLMQLA +PFTF V + AGR Sbjct: 226 AWQVTLFMGLQSLVFYSMVAWMPEILIQKGMSSNKAGWMLSLMQLALIPFTFIVSVIAGR 285 Query: 297 MKNQRSLVVITSILFMIGILGVWLGSTAWMAVWXXXXXXXXXXXXXXXXXXXSLRTRSTQ 356 NQRSLV+ +IGILG+ GS+ ++ +W SLRT ++ Sbjct: 286 RSNQRSLVISGCSFILIGILGLLYGSSQFVFLWIIILGIGGGFAFSLSMMFFSLRTENSN 345 Query: 357 EASELSGMAQSVGYLLAAMGPALFGLLHDVNHSWNVP 393 EA++LSGMAQS+GYLLAA GP LFG LHD +SW VP Sbjct: 346 EAAQLSGMAQSLGYLLAAFGPILFGFLHDATNSWKVP 382 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.326 0.136 0.424 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,973,264,976 Number of extensions: 67379054 Number of successful extensions: 281686 Number of sequences better than 1.0e-05: 584 Number of HSP's gapped: 280014 Number of HSP's successfully gapped: 591 Length of query: 447 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 308 Effective length of database: 1,751,175,118 Effective search space: 539361936344 Effective search space used: 539361936344 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 133 (55.8 bits)