BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0153.0031.p (457 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q5KUP7.1 Q5KUP7_GEOKA Mannose-6-phosphate isomerase (Phosphomann... 619 e-175 Q6T1V9.1 Q6T1V9_ANETH Mannose-1-phosphate guanylyltransferase EC... 599 e-169 A0RL60.1 A0RL60_BACAH Mannose-1-phosphate guanylyltransferase (G... 578 e-163 C1F0I8.1 C1F0I8_BACC3 Mannose-1-phosphate guanylyltransferase 575 e-162 B9J5T5.1 B9J5T5_BACCQ Mannose-1-phosphate guanylyltransferase 573 e-161 >Q5KUP7.1 Q5KUP7_GEOKA Mannose-6-phosphate isomerase (Phosphomannose isomerase) ; mannose-1-phosphate guanylyl transferase (GDP-mannose pyrophosphorylase) EC=2.7.7.22 EC=5.3.1.8 Length = 458 Score = 619 bits (1596), Expect = e-175, Method: Compositional matrix adjust. Identities = 289/455 (63%), Positives = 360/455 (79%), Gaps = 1/455 (0%) Query: 1 MKLVLLSGGSGKRLWPLSNDSRSKQFLKVLQSPAGEPESMVQRVWRQLQETGMADSSYLA 60 MKLVLLSGGSGKRLWPLSND+RSKQFLKVL++ GE +SMVQRVW QL G+ADS+ +A Sbjct: 1 MKLVLLSGGSGKRLWPLSNDARSKQFLKVLETQNGELQSMVQRVWEQLGNVGLADSAVIA 60 Query: 61 TGRSQVEMIQSQLGAEVPIIVEPERRDTFPAIALTAAYLYSIAGVSPRETVAILPVDPYV 120 T +SQV+MIQSQLG +VPII+EP RRDTFPAIAL + YLYS+ G+ E VA+LPVDPYV Sbjct: 61 TSKSQVDMIQSQLGQDVPIIIEPMRRDTFPAIALASVYLYSVEGIRLDEVVAVLPVDPYV 120 Query: 121 EASFFETVVQLEATIQESGANLALMGVVPELASEKYGYIIPTSDEAAASGYMQVSHFQEK 180 E FF V LE T+ SGA+LAL+GV P S KYGYI+P S +++ SGY++VSHF EK Sbjct: 121 EDRFFHRVKDLEETVLASGADLALIGVEPTYPSAKYGYIVPAS-KSSDSGYLRVSHFTEK 179 Query: 181 PDRAQAEELISRGALWNCGVFAFRLGYLLDILQRKGLPLNYEELQKQYKLLSSISFDYEV 240 P +A ELI +GALWNCGVFAF+L Y++ +LQ KG P+ Y+EL KQY L ISFDYEV Sbjct: 180 PTEEKAAELIKQGALWNCGVFAFKLDYIISLLQEKGFPIQYDELLKQYDKLPKISFDYEV 239 Query: 241 VEKEENIVVQPYAGFWKDLGTWNTLTEEMSSNHVGKGFVTADSEGTCLINELDIPVTVIG 300 VEK E+IVV PY G+WKDLGTWNTLTEEM++N +GKG ++AD E T LINELDIPVTV+G Sbjct: 240 VEKTEHIVVLPYDGYWKDLGTWNTLTEEMATNQIGKGVISADCENTHLINELDIPVTVLG 299 Query: 301 AKDLIIAASPDGILVTHKTESPRIKEVLKSFEQRPMYEERRWGHYKVIDYVKYDEGNEVL 360 + ++A SPDGILV K +SP+IKE++ F+QRPMYEERRWG Y+V+DY K+++G EVL Sbjct: 300 ISNAVVAVSPDGILVADKAKSPKIKELVNDFDQRPMYEERRWGWYRVLDYTKFEDGREVL 359 Query: 361 TKRIFISEGKNISYQLHHKRSEIWTIVSGEASIVLNEKMHNVKAGDVVRIPEGTKHAILA 420 TKRI ++ GKN+SYQ+HH RSE+WTI+ GE LN ++ VK GDV+ IP G KH I A Sbjct: 360 TKRIGVTAGKNLSYQMHHHRSEVWTIIKGEGEFALNGEIRRVKPGDVLEIPVGAKHGIKA 419 Query: 421 LTDVEFIEVQTGSELVEEDNIRITLEWEDIALQQF 455 +TD+EFIEVQTG++L+EED +RI + WE++ F Sbjct: 420 ITDLEFIEVQTGTQLIEEDIVRIYMTWEEVEANCF 454 >Q6T1V9.1 Q6T1V9_ANETH Mannose-1-phosphate guanylyltransferase EC=2.7.7.13 Length = 464 Score = 599 bits (1545), Expect = e-169, Method: Compositional matrix adjust. Identities = 277/450 (61%), Positives = 355/450 (78%), Gaps = 1/450 (0%) Query: 1 MKLVLLSGGSGKRLWPLSNDSRSKQFLKVLQSPAGEPESMVQRVWRQLQETGMADSSYLA 60 MKL+LLSGGSGKRLWPLSNDSRSKQFLKVL++ E ESMVQRVW QL G+A+ SY+A Sbjct: 1 MKLILLSGGSGKRLWPLSNDSRSKQFLKVLKNDNNEFESMVQRVWNQLHTVGLAEDSYVA 60 Query: 61 TGRSQVEMIQSQLGAEVPIIVEPERRDTFPAIALTAAYLYSIAGVSPRETVAILPVDPYV 120 T +SQV+M+ +QLG EVP+I+EPERRDTFPAIAL A YLYS+ GV + +++LPVDPYV Sbjct: 61 TSKSQVDMLHAQLGTEVPLIIEPERRDTFPAIALAATYLYSMEGVREDDVISVLPVDPYV 120 Query: 121 EASFFETVVQLEATIQESGANLALMGVVPELASEKYGYIIPTSDEA-AASGYMQVSHFQE 179 E+ FF+ V LE + +S A LAL+GV P SEKYGYI+P E + + V +F E Sbjct: 121 ESRFFDRVKDLETALVQSSAELALIGVKPTFPSEKYGYIVPKKGEHDVVANVLAVDYFVE 180 Query: 180 KPDRAQAEELISRGALWNCGVFAFRLGYLLDILQRKGLPLNYEELQKQYKLLSSISFDYE 239 KP ++A+EL+ + A WNCG+FAF+LGYL+ +L+ K LP +YEE+ Y L ISFDYE Sbjct: 181 KPSTSRAQELMKQQAFWNCGIFAFKLGYLISLLKEKKLPTDYEEMLHTYNQLPKISFDYE 240 Query: 240 VVEKEENIVVQPYAGFWKDLGTWNTLTEEMSSNHVGKGFVTADSEGTCLINELDIPVTVI 299 VVEK +NI++ PY G WKDLGTWNTLTEEM++N +GKG ++ E T LINELDIPVT++ Sbjct: 241 VVEKAQNIIMLPYEGEWKDLGTWNTLTEEMNTNLLGKGIISEGCENTHLINELDIPVTIL 300 Query: 300 GAKDLIIAASPDGILVTHKTESPRIKEVLKSFEQRPMYEERRWGHYKVIDYVKYDEGNEV 359 G + +IAASPDGILVT K SPRIK+++K+F QRPMYEERRWG Y+V+D+ K + GNEV Sbjct: 301 GISNAVIAASPDGILVTDKEASPRIKDIMKNFNQRPMYEERRWGWYRVLDHTKVENGNEV 360 Query: 360 LTKRIFISEGKNISYQLHHKRSEIWTIVSGEASIVLNEKMHNVKAGDVVRIPEGTKHAIL 419 LTKRI + GKN+SYQ+HHKRSE+WTI+SGE VLN+++++VK GDV++IP G KHAI Sbjct: 361 LTKRIGVHAGKNLSYQIHHKRSEVWTIISGEGQFVLNDQLYHVKPGDVLQIPVGAKHAIR 420 Query: 420 ALTDVEFIEVQTGSELVEEDNIRITLEWED 449 A+TD++F+EVQTGSEL+EED IR+ + WE+ Sbjct: 421 AITDLQFVEVQTGSELIEEDIIRLCMTWEE 450 >A0RL60.1 A0RL60_BACAH Mannose-1-phosphate guanylyltransferase (GDP) EC=2.7.7.22 Length = 459 Score = 578 bits (1490), Expect = e-163, Method: Compositional matrix adjust. Identities = 277/450 (61%), Positives = 349/450 (77%), Gaps = 1/450 (0%) Query: 1 MKLVLLSGGSGKRLWPLSNDSRSKQFLKVLQSPAGEPESMVQRVWRQLQETGMADSSYLA 60 MKLVLLSGGSGKRLWPLSNDSRSKQFLKVL+S E +SMVQRVW QL+ G+ + + +A Sbjct: 1 MKLVLLSGGSGKRLWPLSNDSRSKQFLKVLKSEKNEMQSMVQRVWEQLKSLGIENDAVIA 60 Query: 61 TGRSQVEMIQSQLGAEVPIIVEPERRDTFPAIALTAAYLYSIAGVSPRETVAILPVDPYV 120 T +SQV+MI SQLG +VPII+EPERRDTFPAIAL A+YLYS V E V +LPVDPYV Sbjct: 61 TSKSQVDMINSQLGNDVPIIIEPERRDTFPAIALAASYLYSKEHVDLDEVVGVLPVDPYV 120 Query: 121 EASFFETVVQLEATIQESGANLALMGVVPELASEKYGYIIPTSDEAAASGYMQVSHFQEK 180 E SFFE ++ LE + S A+L LMGV P SEKYGYI+P E + +QVSHF+EK Sbjct: 121 ENSFFERLLDLENALNSSNADLGLMGVTPTYPSEKYGYIVPNV-EKSTQELIQVSHFKEK 179 Query: 181 PDRAQAEELISRGALWNCGVFAFRLGYLLDILQRKGLPLNYEELQKQYKLLSSISFDYEV 240 P A+AEEL+ + ALWN GVFAF+L ++ +L +KGLP+ Y+ L +QY L ISFDYEV Sbjct: 180 PATAEAEELLKQNALWNSGVFAFKLDKIISLLDQKGLPVQYDVLVQQYASLPKISFDYEV 239 Query: 241 VEKEENIVVQPYAGFWKDLGTWNTLTEEMSSNHVGKGFVTADSEGTCLINELDIPVTVIG 300 VEK ENI+ PY+G WKDLGTWNTLTEEM +N +GKG + + E +INELDIPV+V+G Sbjct: 240 VEKTENIIALPYSGSWKDLGTWNTLTEEMGTNILGKGNMGVECEQNHIINELDIPVSVLG 299 Query: 301 AKDLIIAASPDGILVTHKTESPRIKEVLKSFEQRPMYEERRWGHYKVIDYVKYDEGNEVL 360 ++I+AASPDGILV+ K SPR+KE++ ++QRPMYEERRWG Y+V+D+ KYD+GNEVL Sbjct: 300 LSNIIVAASPDGILVSEKDASPRVKELVGDWDQRPMYEERRWGWYRVLDHTKYDDGNEVL 359 Query: 361 TKRIFISEGKNISYQLHHKRSEIWTIVSGEASIVLNEKMHNVKAGDVVRIPEGTKHAILA 420 TKRI I+ KN+SYQ H+ RSE+WT+V GE VL+E++ V+ GDV+ I G KHAI A Sbjct: 360 TKRIGITASKNLSYQYHNNRSEVWTVVKGEGIFVLDEEIRVVRPGDVLEIQPGQKHAIKA 419 Query: 421 LTDVEFIEVQTGSELVEEDNIRITLEWEDI 450 +TD+EFIEVQ+GSEL+EED +RI ++W +I Sbjct: 420 VTDLEFIEVQSGSELIEEDIVRIYMQWNEI 449 >C1F0I8.1 C1F0I8_BACC3 Mannose-1-phosphate guanylyltransferase Length = 457 Score = 575 bits (1481), Expect = e-162, Method: Compositional matrix adjust. Identities = 276/450 (61%), Positives = 348/450 (77%), Gaps = 1/450 (0%) Query: 1 MKLVLLSGGSGKRLWPLSNDSRSKQFLKVLQSPAGEPESMVQRVWRQLQETGMADSSYLA 60 MKLVLLSGGSGKRLWPLSNDSRSKQFLKVL+S E +SMVQRVW QL+ G+ + + +A Sbjct: 1 MKLVLLSGGSGKRLWPLSNDSRSKQFLKVLKSEKNEMQSMVQRVWEQLKSLGIENDAVIA 60 Query: 61 TGRSQVEMIQSQLGAEVPIIVEPERRDTFPAIALTAAYLYSIAGVSPRETVAILPVDPYV 120 T +SQV+MI SQLG +V II+EPERRDTFPAIAL A+YLYS V E V +LPVDPYV Sbjct: 61 TSKSQVDMINSQLGNDVSIIIEPERRDTFPAIALAASYLYSKEHVDLDEVVGVLPVDPYV 120 Query: 121 EASFFETVVQLEATIQESGANLALMGVVPELASEKYGYIIPTSDEAAASGYMQVSHFQEK 180 E SFFE ++ LE + S A+L LMGV P SEKYGYI+P E + +QVSHF+EK Sbjct: 121 ENSFFERLLDLENALNSSSADLGLMGVTPTYPSEKYGYIVPNV-EKSTQELIQVSHFKEK 179 Query: 181 PDRAQAEELISRGALWNCGVFAFRLGYLLDILQRKGLPLNYEELQKQYKLLSSISFDYEV 240 P A+AEEL+ + ALWN GVFAF+L ++ +L +KGLP+ Y+ L +QY L ISFDYEV Sbjct: 180 PATAEAEELLKQNALWNSGVFAFKLDKIISLLDQKGLPVQYDMLVQQYASLPKISFDYEV 239 Query: 241 VEKEENIVVQPYAGFWKDLGTWNTLTEEMSSNHVGKGFVTADSEGTCLINELDIPVTVIG 300 VEK ENI+ PY+G WKDLGTWNTLTEEM +N +GKG + + E +INELDIPV+V+G Sbjct: 240 VEKTENIIALPYSGSWKDLGTWNTLTEEMGTNILGKGNMGIECEQNHIINELDIPVSVLG 299 Query: 301 AKDLIIAASPDGILVTHKTESPRIKEVLKSFEQRPMYEERRWGHYKVIDYVKYDEGNEVL 360 ++I+AASPDGILV+ K SPR+KE++ ++QRPMYEERRWG Y+V+D+ KYD+GNEVL Sbjct: 300 LSNIIVAASPDGILVSEKDASPRVKELVGDWDQRPMYEERRWGWYRVLDHTKYDDGNEVL 359 Query: 361 TKRIFISEGKNISYQLHHKRSEIWTIVSGEASIVLNEKMHNVKAGDVVRIPEGTKHAILA 420 TKRI I+ KN+SYQ H+ RSE+WT+V GE VL+E++ V+ GDV+ I G KHAI A Sbjct: 360 TKRIGITASKNLSYQYHNNRSEVWTVVKGEGIFVLDEEIRVVRPGDVLEIQPGQKHAIKA 419 Query: 421 LTDVEFIEVQTGSELVEEDNIRITLEWEDI 450 +TD+EFIEVQ+GSEL+EED +RI ++W +I Sbjct: 420 VTDLEFIEVQSGSELIEEDIVRIYMQWNEI 449 >B9J5T5.1 B9J5T5_BACCQ Mannose-1-phosphate guanylyltransferase Length = 457 Score = 573 bits (1476), Expect = e-161, Method: Compositional matrix adjust. Identities = 275/450 (61%), Positives = 348/450 (77%), Gaps = 1/450 (0%) Query: 1 MKLVLLSGGSGKRLWPLSNDSRSKQFLKVLQSPAGEPESMVQRVWRQLQETGMADSSYLA 60 MKL+LLSGGSGKRLWPLSNDSRSKQFLKVL++ E +SMVQRVW QL+ G+ + + +A Sbjct: 1 MKLILLSGGSGKRLWPLSNDSRSKQFLKVLKNENDEMQSMVQRVWGQLKSLGIENDAVIA 60 Query: 61 TGRSQVEMIQSQLGAEVPIIVEPERRDTFPAIALTAAYLYSIAGVSPRETVAILPVDPYV 120 T +SQV+MI SQLG VPII+EPERRDTFPAIAL A+YLYS V E + +LPVDPYV Sbjct: 61 TSKSQVDMINSQLGNGVPIIIEPERRDTFPAIALAASYLYSKEHVDLEEVIGVLPVDPYV 120 Query: 121 EASFFETVVQLEATIQESGANLALMGVVPELASEKYGYIIPTSDEAAASGYMQVSHFQEK 180 E SFFE ++ LE T+ S A+L LMG+ P SEKYGYI+P E + +QVSHF+EK Sbjct: 121 ENSFFERLLDLEKTLNSSNADLGLMGITPTYPSEKYGYIVPNV-EKSTQELIQVSHFKEK 179 Query: 181 PDRAQAEELISRGALWNCGVFAFRLGYLLDILQRKGLPLNYEELQKQYKLLSSISFDYEV 240 P A+AEEL+ + ALWN GVFAF+L ++ +L +KGLP+ Y+ L +QY+ L ISFDYEV Sbjct: 180 PATAEAEELLKQNALWNSGVFAFKLDKIISLLDQKGLPVQYDVLVQQYETLPKISFDYEV 239 Query: 241 VEKEENIVVQPYAGFWKDLGTWNTLTEEMSSNHVGKGFVTADSEGTCLINELDIPVTVIG 300 VEK ENIV PY G WKDLGTWNTLTEEM +N +GKG + + E +INELDIPV+V+G Sbjct: 240 VEKTENIVALPYNGPWKDLGTWNTLTEEMGTNILGKGNMGVECEQNHIINELDIPVSVLG 299 Query: 301 AKDLIIAASPDGILVTHKTESPRIKEVLKSFEQRPMYEERRWGHYKVIDYVKYDEGNEVL 360 ++I+A SPDGILV+ K SPR+KE++ ++QRPMYEERRWG Y+V+D+ KYD+GNEVL Sbjct: 300 LSNIIVAVSPDGILVSEKDASPRVKELVGDWDQRPMYEERRWGWYRVLDHTKYDDGNEVL 359 Query: 361 TKRIFISEGKNISYQLHHKRSEIWTIVSGEASIVLNEKMHNVKAGDVVRIPEGTKHAILA 420 TKRI I+ KN+SYQ H+ RSE+WTIV GE VL++++ V++GDV+ I G KHAI A Sbjct: 360 TKRIGITASKNLSYQYHNNRSEVWTIVKGEGIFVLDDEIRVVRSGDVLEIQPGQKHAIKA 419 Query: 421 LTDVEFIEVQTGSELVEEDNIRITLEWEDI 450 +TD+EFIEVQ+GSELVEED +RI + W +I Sbjct: 420 VTDLEFIEVQSGSELVEEDIVRIYMHWNEI 449 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.316 0.133 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,668,810,136 Number of extensions: 110536296 Number of successful extensions: 339240 Number of sequences better than 1.0e-05: 1335 Number of HSP's gapped: 332785 Number of HSP's successfully gapped: 1366 Length of query: 457 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 318 Effective length of database: 1,751,175,118 Effective search space: 556873687524 Effective search space used: 556873687524 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 133 (55.8 bits)