BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0153.0004.p (470 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KEB5.1 B3KEB5_9BACI Deoxyguanosinetriphosphate triphosphohydro... 760 0.0 B1DKT3.1 B1DKT3_9BACL Deoxyguanosinetriphosphate triphosphohydro... 467 e-129 C5A8S6.1 C5A8S6_BURGL Deoxyguanosinetriphosphate triphosphohydro... 180 2e-43 B4U8T8.1 B4U8T8_HYDS0 Deoxyguanosinetriphosphate triphosphohydro... 176 3e-42 B4TEI7.1 B4TEI7_SALHS Deoxyguanosinetriphosphate triphosphohydro... 176 4e-42 >B3KEB5.1 B3KEB5_9BACI Deoxyguanosinetriphosphate triphosphohydrolase Length = 471 Score = 760 bits (1963), Expect = 0.0, Method: Compositional matrix adjust. Identities = 367/472 (77%), Positives = 403/472 (85%), Gaps = 3/472 (0%) Query: 1 MTLIEKREHRQYPEITRLETSRAAYERDYSRLIHSPTFRRLQGKSQVFGAGTGDYYRTRL 60 MTL E REHRQYPE T+ + SRA YERDYSRLIHSPTFRRLQGKSQVFGAGTGDYYRTRL Sbjct: 1 MTLKELREHRQYPEQTKSDASRAVYERDYSRLIHSPTFRRLQGKSQVFGAGTGDYYRTRL 60 Query: 61 THSLEVAQIAREAAKSLLRAYPEVETGQAENPGLVIDPEVVECAAIAHDFGHPPFGHKGE 120 THSLEVAQIAREAA+SL R YPEV QAEN GL+IDPEVVECAAIAHDFGHPPFGHKGE Sbjct: 61 THSLEVAQIAREAARSLTRLYPEVLPEQAENAGLMIDPEVVECAAIAHDFGHPPFGHKGE 120 Query: 121 EVLDSILERLVVKKTAEAVQKSGAGPVQQQT--IRENMRRKYEHFEGNAHNFRLIMFLEK 178 EVL ILE+L+ ++T + + + P +Q +++ MRRKYEHFEGNAHNFRLIMFLEK Sbjct: 121 EVLQGILEKLIDRRTEKELTRQPGTPTPEQAAEVQQAMRRKYEHFEGNAHNFRLIMFLEK 180 Query: 179 RENIDGLNLSDAVLLGINKYPFPGTVLKKGMYLHEWNYISDIRSQWGIPDGKKTLEAQLM 238 REN++GLNLSDAVLLGINKYPF G V KGMY HEW YIS IR +W IP +TLEAQLM Sbjct: 181 RENVNGLNLSDAVLLGINKYPFSGLVNPKGMYRHEWEYISHIRKEWQIPGTHRTLEAQLM 240 Query: 239 DLCDDIAYSAHDLEDGIKAGKIEVHEHFMHDAYIQRLIVEKITTLEDAFWTGWKEADIHI 298 DLCDDIAYSAHDLEDGIKAGKIEVHEHF+ D+++ +LIV+KI TLED W GW + I Sbjct: 241 DLCDDIAYSAHDLEDGIKAGKIEVHEHFLRDSHLNKLIVQKIMTLEDEVWKGWTKEQIQP 300 Query: 299 KVEEVLSSFLHVWMEKMPTCENDYSRTRREVKAYWVSTFVASLGVIADGNWKKVTFIKDG 358 KV+ VL FL +W EKMPTCENDYSRTRREVKAYWVS FV SLGVIA+G+WKKVTF+KDG Sbjct: 301 KVDLVLDEFLKIWNEKMPTCENDYSRTRREVKAYWVSLFVGSLGVIANGDWKKVTFVKDG 360 Query: 359 QEDEDMLRTVSVLKSFAWVTMIRDLRVQRLQKRSEWILRRLWEAFLDPETSRAIIPSDWL 418 EDEDMLRTVSVLKSFAWVTMIRDLRVQRLQKRSEWI++RLW+AFLDP S AIIPSDWL Sbjct: 361 VEDEDMLRTVSVLKSFAWVTMIRDLRVQRLQKRSEWIIKRLWDAFLDPVASTAIIPSDWL 420 Query: 419 QRFEXXXXGEEKPIWTWEHMVIDYIAGMTDAFAEKIYNELYGLKVGSIYDLD 470 QR+E +PIWTWEHMVIDYIAGMTDAFAEKIYNELYGLKVGSIYDLD Sbjct: 421 QRYEADQK-RAQPIWTWEHMVIDYIAGMTDAFAEKIYNELYGLKVGSIYDLD 471 >B1DKT3.1 B1DKT3_9BACL Deoxyguanosinetriphosphate triphosphohydrolase Length = 438 Score = 467 bits (1202), Expect = e-129, Method: Compositional matrix adjust. Identities = 242/465 (52%), Positives = 311/465 (66%), Gaps = 44/465 (9%) Query: 13 PEITRLETSRAAYERDYSRLIHSPTFRRLQGKSQVFGAGTGDYYRTRLTHSLEVAQIARE 72 P + R YERDY+RLI SP FRRLQGKSQVFGAG+GDYYRTRLTHSLEV+QIARE Sbjct: 11 PALGTFSEERDEYERDYARLIQSPAFRRLQGKSQVFGAGSGDYYRTRLTHSLEVSQIARE 70 Query: 73 AAKSLLRAYPEVETGQAENPGLVIDPEVVECAAIAHDFGHPPFGHKGEEVLDSILERLVV 132 A+ L + YP + + E+PGL++DP VVE AA+AHD GHPPFGHKGEEVL+ RL++ Sbjct: 71 VARRLGKQYPFL--SKKEHPGLIMDPSVVEIAALAHDLGHPPFGHKGEEVLN----RLLL 124 Query: 133 KKTAEAVQKSGAGPVQQQTIRENMRRKYEHFEGNAHNFRLIMFLEKRENI-DGLNLSDAV 191 ++ A +EGNA NFR++MFLEKR GL+L+ AV Sbjct: 125 EEHGLA------------------------YEGNAQNFRILMFLEKRAGSGSGLDLTAAV 160 Query: 192 LLGINKYPF----PGTVLKKGMYLHEWNYISDIRSQWGIPDGKKTLEAQLMDLCDDIAYS 247 LL +NKYP+ PG + KG+Y EW+ I+ IR QW +P G TLEAQLMDLCDDIAYS Sbjct: 161 LLAVNKYPYSLDEPGRL--KGLYSSEWHAINHIRQQWAMPVGSSTLEAQLMDLCDDIAYS 218 Query: 248 AHDLEDGIKAGKIEVHEHFMHDAYIQRLIVEKITTLEDAFWTGWKEADIHIKVEEVLSSF 307 HD+EDGI+AGKI+++ F D + +V++I + GW + DI V VL+++ Sbjct: 219 THDIEDGIRAGKIQMNRTFFEDQRLIDNLVQEIVEDQGNMDVGWDQVDIPAMVGRVLAAY 278 Query: 308 LHVWMEKMPTCENDYSRTRREVKAYWVSTFVASLGVIAD--GNWKKVTFIKDGQEDEDML 365 L W E +++ SRTRRE+KA WVS F +G+I D WKKVTF+ DGQ+D D+L Sbjct: 279 LLQWEELYALYDHESSRTRREMKARWVSVFAGRVGIIEDPVKGWKKVTFVLDGQQDIDLL 338 Query: 366 RTVSVLKSFAWVTMIRDLRVQRLQKRSEWILRRLWEAFLDPETSRAIIPSDWLQRFEXXX 425 RT+ +LK AWVT+I+D RVQRLQ RSE ++RRLW++F PE R I+P DW+ FE Sbjct: 339 RTMEILKKLAWVTLIKDFRVQRLQMRSEIMIRRLWDSFKRPEQGRLILPPDWVASFE--- 395 Query: 426 XGEEKPIWTWEHMVIDYIAGMTDAFAEKIYNELYGLKVGSIYDLD 470 + K WTW + DYI+GMTDA+AEK+Y ELY K GSIY++D Sbjct: 396 --QHKHNWTWARFIADYISGMTDAYAEKVYAELYASKSGSIYEMD 438 >C5A8S6.1 C5A8S6_BURGL Deoxyguanosinetriphosphate triphosphohydrolase Length = 472 Score = 180 bits (457), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 140/487 (28%), Positives = 229/487 (47%), Gaps = 95/487 (19%) Query: 19 ETSRAAYERDYSRLIHSPTFRRLQGKSQVFGAGTGDYYRTRLTHSLEVAQIAREAAKSLL 78 + +RA + RDY+RL+H FRRLQGK+Q+F G D++R RLTHS+EVAQIA+ A L Sbjct: 27 DKTRAHFRRDYARLVHCAAFRRLQGKTQLFPGGESDFFRNRLTHSIEVAQIAKGIAIRL- 85 Query: 79 RAYPEVETGQAENPGLV---IDPEVVECAAIAHDFGHPPFGHKGEEVLDSILERLVVKKT 135 A+ P L+ I+ ++VE AA+AHD GHPPFGH GE LD Sbjct: 86 ---------NAKTPQLIKQKINTDLVELAALAHDIGHPPFGHNGEHALD----------- 125 Query: 136 AEAVQKSGAGPVQQQTIRENMRRKYEHFEGNAHNFRLIMFLEKRENID-------GLNLS 188 E + G FEGNA R+I LEKRE D GLNL+ Sbjct: 126 -ECMANHGG------------------FEGNAQTLRIITRLEKRETNDEAAASKSGLNLT 166 Query: 189 DAVLLGINKYP--FP--------GTVLKKGMYLHEWNYISDIRSQW--GIPDGK-KTLEA 235 + + KY P L KG Y E + ++ ++ G+ K KT+E Sbjct: 167 HRSIAALLKYNQRIPRKQKDRKDPQKLAKGYYESETDLVASVKKAVAPGLAGSKFKTVEC 226 Query: 236 QLMDLCDDIAYSAHDLEDGIKAG---KIEVHEHFMHDAYIQRL-------IVEKITT--- 282 Q+MD+ DDIAYS +DLED KAG +E+ D ++++ I EK +T Sbjct: 227 QIMDIADDIAYSTYDLEDAFKAGFFDPLEIVSLTADDDMLKKITDKVNEAIGEKFSTIYI 286 Query: 283 ---LEDAFWTGWKEADIHIKVEEVL----SSFLHVWMEKMPTCENDYSRTRREVKAYWVS 335 + AF +++ D +I ++ + + + V+ N + RT + + V Sbjct: 287 QNVIVKAFIRIFEKLDNNIPSDDEIMNRAAQVVAVYRHSKKISSNGFFRT--QFTSELVK 344 Query: 336 TFVASLGVIADGNWKKVTFIKDGQEDEDMLRTVSVLKSFAWVTMIRDLRVQRLQKRSEWI 395 F+ +G+ + N K+ K + E ++ + LK + + R++ ++ R + Sbjct: 345 EFIQGVGI--EFNEKQPALSKINVDPEVRVK-IETLKHLTFEALTMSPRMRLVEYRGRDV 401 Query: 396 LRRLWEAFL-DPETSRAIIPSDWLQRFEXXXXGEEKPIWTWEHMVIDYIAGMTDAFAEKI 454 +++++ D + ++P DW + +++ + + D++AGMTD +A + Sbjct: 402 VKQIFSTLAQDEKKGHLLLPDDWRHEYATTNKMQQRRV------ICDFVAGMTDRYAMEF 455 Query: 455 YNELYGL 461 + L + Sbjct: 456 FARLTSI 462 >B4U8T8.1 B4U8T8_HYDS0 Deoxyguanosinetriphosphate triphosphohydrolase Length = 424 Score = 176 bits (447), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 139/462 (30%), Positives = 218/462 (47%), Gaps = 87/462 (18%) Query: 22 RAAYERDYSRLIHSPTFRRLQGKSQVFGAGTGDYYRTRLTHSLEVAQIAREAAKSLLRAY 81 R+ +ERD +R+IHS FRRLQGK+Q+ G D+YRTRLTHSLEVAQI++ Sbjct: 35 RSDFERDRARIIHSSAFRRLQGKTQIMSPGYLDFYRTRLTHSLEVAQISK---------- 84 Query: 82 PEVETGQAENPGLVIDPEVVECAAIAHDFGHPPFGHKGEEVLDSILERLVVKKTAEAVQK 141 G A G ID +VE ++AHD GHPP GH GE Sbjct: 85 -----GMAIKHG--IDSTIVEAISLAHDIGHPPLGHSGE--------------------- 116 Query: 142 SGAGPVQQQTIRENMRRKYEH--FEGNAHNFRLIMFLE----KRENIDGLNLSDAVLLGI 195 QT+RE M+ EH FE NA N R++ +LE K + GLNL+ AVL G+ Sbjct: 117 --------QTLRELMK---EHGLFESNAQNIRILTYLEIKTLKDDKSYGLNLTRAVLDGV 165 Query: 196 NKYP-FPGTVLKKGMYLH---EWNYISDIRSQWGIPDGKKTLEAQLMDLCDDIAYSAHDL 251 KY F KKG+Y E +I +P +E Q+MD DDIAYS HD+ Sbjct: 166 IKYKGFLTKENKKGLYKENEMELEFIDPYYQDAQVP-----IETQIMDWADDIAYSVHDI 220 Query: 252 EDGIKAGKIEVHEHFMHDAYIQRLIVEKI--TTLEDAFWTGWKEADIHIKVEEVLSSFLH 309 EDG++ + I ++++KI LEDA + ++ E+ L F Sbjct: 221 EDGVRL------------SLINSIVIDKIGQKILEDAKASNIDKS----FAEKTLEDFQE 264 Query: 310 VWMEKMPTCENDYSRTRREVKAYWVSTFVASLGVIADGNWKKVTFIKDG--QEDEDMLRT 367 + + + + ++ + F+ + + + + T D + DE+ Sbjct: 265 ELYKIQKAGAFERKKLLKSFTSFRIHKFINATKIEQNDKRRPNTQRYDYKLKVDEEAKWE 324 Query: 368 VSVLKSFAWVTMIRDLRVQRLQKRSEWILRRLWEAFLDPETSRAIIPSDWLQRFEXXXXG 427 V +LK+ + I D R+++L+ + ++++ L+ L + ++ P D+ ++ Sbjct: 325 VVILKNISKELFINDYRLEQLRHKLSFVIKELF-GLLSQKDAKKYYPDDFKYMWDINNCD 383 Query: 428 EEKPIWTWEHMVIDYIAGMTDAFAEKIYNELYGLKVGSIYDL 469 ++ + + DYIAGMTD FA K+Y L+ ++D+ Sbjct: 384 HDEKMRF--RLACDYIAGMTDNFALKLYRRLFSPSNDGLFDI 423 >B4TEI7.1 B4TEI7_SALHS Deoxyguanosinetriphosphate triphosphohydrolase Length = 410 Score = 176 bits (447), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 139/460 (30%), Positives = 219/460 (47%), Gaps = 85/460 (18%) Query: 2 TLIEKREHRQYPEITRLETSRAAYERDYSRLIHSPTFRRLQGKSQVFGAGTGDYYRTRLT 61 L + REH TR SR Y+RDY+R+++S +FRRLQGK Q+F + R RLT Sbjct: 20 ALADTREHPSPDGETR---SRDNYQRDYARILYSSSFRRLQGKMQLFEIDPEKFNRNRLT 76 Query: 62 HSLEVAQIAREAAKSLLRAYPEVETGQAENPGLVIDPEVVECAAIAHDFGHPPFGHKGEE 121 HSLEVAQIAR A L +I+P VVE AA+AHD G+PPFGH GE+ Sbjct: 77 HSLEVAQIARSIASDL----------------KLINPVVVELAALAHDIGNPPFGHSGEK 120 Query: 122 VLDSILERLVVKKTAEAVQKSGAGPVQQQTIRENMRRKYEHFEGNAHNFRLIMFLEKREN 181 +L+ + E + G +EGNA R++ LEK+ + Sbjct: 121 LLNELSEEI------------GG------------------YEGNAQALRILRKLEKKFS 150 Query: 182 -IDGLNLSDAVLLGINKYPFPGTVLKKGMYLHEWNYISDIR----SQWGIPDGKKTLEAQ 236 +GLNL+ LL + KYP P G ++++ +Y I +Q + G+KT++AQ Sbjct: 151 YCNGLNLTHRSLLSVVKYPIPRAAATAGKFIYDDDYYFYINLLAENQLDLNPGEKTIDAQ 210 Query: 237 LMDLCDDIAYSAHDLEDGIKAGKIEVHEHFMHDAYIQRLIVEKITTLEDAFWTGWKEADI 296 +MDL D+IAY+AHDLED + + + + +E + D F G +E Sbjct: 211 IMDLADEIAYAAHDLEDALSRNMVTIED------------IEYEFQISDEF-RGAREQFR 257 Query: 297 HIKVEEVLSSFLHVWMEKMPTCENDYSRTRREVKAYWVSTFVASLGVIADGN-WKKVTFI 355 I + ++F + T E R+E+ + V+ VA + V+ + N ++++ F Sbjct: 258 EIVTQSRNTAF---QANLLKTSEEFAIIFRKELTSNIVNRLVADISVVTNLNGFQELGFG 314 Query: 356 KDGQEDEDMLRTVSVLKSFAWVTMIRDLRVQRLQKRSEWILRRLWEAFLDPETSRAIIPS 415 K E LK + ++R + + R I+R L++ + + E + + P Sbjct: 315 KLNALSEG-------LKKLLFKVIMRKRNILTYEFRGNKIIRDLYDFYNEGENYKFLPPE 367 Query: 416 DWLQRFEXXXXGEEKPIW--TWEHMVIDYIAGMTDAFAEK 453 + + I+ + + V+DYI+GM D FA K Sbjct: 368 -----LKFTLPQPDSCIFEISKKRAVVDYISGMMDTFAVK 402 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.136 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,902,023,701 Number of extensions: 120335053 Number of successful extensions: 283110 Number of sequences better than 1.0e-05: 1049 Number of HSP's gapped: 280766 Number of HSP's successfully gapped: 1165 Length of query: 470 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 331 Effective length of database: 1,751,175,118 Effective search space: 579638964058 Effective search space used: 579638964058 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 133 (55.8 bits)