BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0149.0014.p (618 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A9U7E1.1 A9U7E1_PHYPA Predicted protein (Fragment) 275 1e-71 B0K338.1 B0K338_THEPX Histidine kinase internal region 143 7e-32 B1DIP7.1 B1DIP7_9BACL Histidine kinase 137 3e-30 C4G4K8.1 C4G4K8_ABIDE Putative uncharacterized protein 135 1e-29 B8HZZ4.1 B8HZZ4_CLOCE Putative sensor with HAMP domain 135 2e-29 >A9U7E1.1 A9U7E1_PHYPA Predicted protein (Fragment) Length = 458 Score = 275 bits (702), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 136/233 (58%), Positives = 156/233 (66%), Gaps = 1/233 (0%) Query: 377 MLVTLHGLIEKSFXXXXXXXXXXXXXXHAQINPHFIYNTLDLINCRAIMAGDMESSKIVR 436 MLVTLHGLIEKSF +AQINPHF+YNTLDLINCRAI+AGD E+S +VR Sbjct: 1 MLVTLHGLIEKSFEEEIERRQLQLELLNAQINPHFLYNTLDLINCRAILAGDRETSAVVR 60 Query: 437 SLANVFRFSLNRGQTLISLEEEIKQVEAYLHIQKMMMDHLQVIIQVPVGLLQARMVHLTL 496 SLANVFRF LNRG+T ISL+ EIKQVEAYLHIQ+MM D L + L + H L Sbjct: 61 SLANVFRFGLNRGRTWISLDNEIKQVEAYLHIQQMMHDDLLAEFHIASDLQDIVIPHFIL 120 Query: 497 QPLAENAIVHGFTDRQSDCRITITAXXXXXXXXXXVEDNGTGCDVERMNEALQEKPASEP 556 QPLAENAIVHGF R DCRI ITA VEDNG GC +E N L+E+ + E Sbjct: 121 QPLAENAIVHGFAGRTDDCRIAITAYAEGNTLILHVEDNGKGCSIEERNRVLREQESGEH 180 Query: 557 GIKLLEPG-NGYGMMNVHRRIQLHCGKAYGLRYLPAAKGTCVEAVLPFYSDSI 608 G+ NGYG +NVHRRIQLHCG +GLRY+P +GTCVE VLP S + Sbjct: 181 GLTSNSSAENGYGTLNVHRRIQLHCGPGFGLRYVPVDEGTCVEVVLPLRSHDV 233 >B0K338.1 B0K338_THEPX Histidine kinase internal region Length = 567 Score = 143 bits (360), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 111/436 (25%), Positives = 193/436 (44%), Gaps = 25/436 (5%) Query: 150 YPV----TGIFKSDDLKNQPWFRSLSSKERQTEWWGERTDRPEGAMIYSARRKTSLKD-G 204 YP+ + S ++N+ W++ + W+ D MI +R +K+ Sbjct: 121 YPMRLEQNDVMSSKVVENKEWYKKTIQLNGRLYWY--INDDFGKQMISVSRLVFDIKNFA 178 Query: 205 RSIGTVIVGASIRSIQSVFRNAEL-EQGYHLLLDEGNRVIFSERYSFLESADELPVVRAL 263 + I + V + + SV + L + G L+D+ ++I+SE SFL + Sbjct: 179 KPIAVISVDMDMSKVASVVSDIHLGKTGKVYLVDDKGKLIYSEDKSFLYRY----TTKLY 234 Query: 264 DASKESMIANIDGEKQRVMSETF-ENGWRLLTIVPESHISRYTXXXXXXXXXXXXXXXXX 322 ++S S I+G K V+ T +NGW+L+ +V + ++ Sbjct: 235 NSSSGSDFITINGNKIMVIYNTLPQNGWKLVGMVSMAELNEKAEMIRNFIYLTALLSLVI 294 Query: 323 XXFWXXXXXXXXXXXXXXXXXXXQRLEVSGFKDTLPQQKSGIYEVDELSQTFGSMLVTLH 382 +++E F ++ + G E+ L +F M+ ++ Sbjct: 295 AALISLYFSYSISQPIIKLATEMKKVEKGNFNISVEENWDG--EIGVLYSSFNYMIERIN 352 Query: 383 GLIEKSFXXXXXXXXXXXXXXHAQINPHFIYNTLDLINCRAIMAGDMESSKIVRSLANVF 442 LI + + AQINPHF+YNTLD +N A+ E SKIV SLA++ Sbjct: 353 ELIHEVYLSKIKEKDAELKALQAQINPHFLYNTLDTVNWLAVKHNVPEISKIVNSLASIL 412 Query: 443 RFSLNRGQTLISLEEEIKQVEAYLHIQKM-MMDHLQVIIQVPVGLLQARMVHLTLQPLAE 501 R+S+N+G + ++E E+K VE+Y+ IQK+ D +V + +L + + L LQPL E Sbjct: 413 RYSINKGNDVTTVENELKHVESYITIQKIRFKDKFEVSFNIDKRVLHYKTIKLILQPLVE 472 Query: 502 NAIVHGFTDRQSDCRITITAXXXXXXXXXXVEDNGTGCDVERMNEALQEKPASEPGIKLL 561 NAI+HG + +I I V +NG D++ +N+ L + PA + Sbjct: 473 NAIIHGIETYEGKGKILINGYLDGEKIVFEVINNGNPIDLDLVNKLL-DSPADDK----- 526 Query: 562 EPGNGYGMMNVHRRIQ 577 + YG+ NV+ RI+ Sbjct: 527 ---DSYGIQNVNERIK 539 >B1DIP7.1 B1DIP7_9BACL Histidine kinase Length = 254 Score = 137 bits (345), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 82/240 (34%), Positives = 129/240 (53%), Gaps = 12/240 (5%) Query: 368 DELSQTFGS---MLVTLHGLIEKSFXXXXXXXXXXXXXXHAQINPHFIYNTLDLINCRAI 424 DE+ G+ M L+GLI + + QINPH +YNTL+ I ++ Sbjct: 11 DEVGVLIGALYDMARRLNGLIHDKYQMEIKQRESQLQILYQQINPHLLYNTLESIYWKSS 70 Query: 425 MAGDMESSKIVRSLANVFRFSLNRGQTLISLEEEIKQVEAYLHIQKMMMDH-LQVIIQVP 483 + G+ ES+++++ L+ + + SL+RG+ LI+L EE++ AY+ +Q+ D+ QVI VP Sbjct: 71 LEGNSESAEMIKELSKLMKISLSRGRELITLAEELEHAAAYVKLQQKRYDYDFQVIWAVP 130 Query: 484 VGLLQARMVHLTLQPLAENAIVHGFTDRQSDCRITITAXXXXXXXXXXVEDNGTGCDVER 543 ++ + +TLQPL ENAI+HG + D I I A VEDNG + Sbjct: 131 EEMMNHLIPKVTLQPLIENAIIHGVKNMGEDGEIHINAEYEGDKLLIRVEDNGYKEVDHK 190 Query: 544 MNEALQEKPASEPGIKLLEPGNGYGMMNVHRRIQLHCGKAYGLRYLP-AAKGTCVEAVLP 602 E+L +PA+ + +GYG+ N+H+R+QLH G YG++Y GT V +LP Sbjct: 191 AIESLLNEPAA-------QSSSGYGVKNIHQRLQLHFGNVYGIQYKKRNGGGTIVTIMLP 243 >C4G4K8.1 C4G4K8_ABIDE Putative uncharacterized protein Length = 599 Score = 135 bits (341), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 82/261 (31%), Positives = 139/261 (53%), Gaps = 24/261 (9%) Query: 363 GIYEVDELSQTFGSMLVTLHGLIEKSFXXXXXXXXXXXXXXHAQINPHFIYNTLDLINCR 422 G E+ EL +F +M + + +I++ + AQINPHF+YN+LDL+NC Sbjct: 356 GSDEIGELMSSFQAMTLRMEEMIDEKYRMGKEVKNAELKALQAQINPHFLYNSLDLVNCL 415 Query: 423 AIMAGDMESSKIVRSLANVFRFSLNRGQTLISLEEEIKQVEAYLHIQKMMMD---HLQVI 479 AI E + ++ SL ++ SLNRGQ ++SL +E++ V+ Y+ IQ M + L+ I Sbjct: 416 AIQHNVPEIADMINSLVEFYKLSLNRGQEILSLYDELRHVQTYVRIQNMRFEKKIRLE-I 474 Query: 480 IQVPVGLLQARMVHLTLQPLAENAIVHGFTDRQ-SDCRITITAXXXXXXXXXXVEDNGTG 538 I+ P + + ++ + LQPL EN+I+HG +++ S I I++ +ED+G G Sbjct: 475 IEEP-WMKKYAILKIILQPLVENSIMHGILEKEDSRGEIKISSELKDNRIYITIEDDGVG 533 Query: 539 CDVERMNEALQEKPASEPGIKLLEPGNGYGMMNVHRRIQLHCGKAYGLRYLP-AAKGTCV 597 + ++ L+E ++ G+GYG+ N++ RI+L+ G YGL + KGT V Sbjct: 534 MSLNQIENLLKETN------EVRHRGSGYGVKNINERIKLYYGADYGLIFESRENKGTTV 587 Query: 598 EAVLPFYSDSILPEMEAVPYV 618 +P A+PY+ Sbjct: 588 TVSIP-----------AIPYI 597 >B8HZZ4.1 B8HZZ4_CLOCE Putative sensor with HAMP domain Length = 597 Score = 135 bits (339), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 77/224 (34%), Positives = 122/224 (54%), Gaps = 14/224 (6%) Query: 369 ELSQTFGSMLVTLHGLIEKSFXXXXXXXXXXXXXXHAQINPHFIYNTLDLINCRAIMAGD 428 ++SQ F M+ + L++K + +QINPHF+YNTL+ I+ +A++ G Sbjct: 361 QVSQGFNIMVEHIDELMKKIYEEQRQLKEIEFKALQSQINPHFLYNTLESIHWQALLYGH 420 Query: 429 MESSKIVRSLANVFRFSLNRGQTLISLEEEIKQVEAYLHIQKM-MMDHLQVIIQVPVGLL 487 + S +V++LA +R SL++G+ +I L+ E + VE Y+ IQ++ D ++ I +P Sbjct: 421 HDISTMVKALAGFYRISLSKGEDIIPLKNESEHVENYMTIQEIRYKDKMESYIDIPEEFY 480 Query: 488 QARMVHLTLQPLAENAIVHGFTDRQSDCRITITAXXXXXXXXXXVEDNGTGCDVE---RM 544 ++ + LQPL ENAI HG R++ I ITA DNGTG V+ ++ Sbjct: 481 DVKIPKMILQPLVENAIYHGLRGRKAKGFIKITAERDGDDIIVKTIDNGTGMTVDQICKL 540 Query: 545 NEALQEKPASEPGIKLLEPGNGYGMMNVHRRIQLHCGKAYGLRY 588 N+ L++ +P GYG+ NVHRRI+L G YGL Y Sbjct: 541 NQTLEDN----------DPSVGYGVRNVHRRIKLFLGSPYGLYY 574 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.135 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,878,068,153 Number of extensions: 100851172 Number of successful extensions: 233117 Number of sequences better than 1.0e-05: 1668 Number of HSP's gapped: 230448 Number of HSP's successfully gapped: 1668 Length of query: 618 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 476 Effective length of database: 1,722,912,073 Effective search space: 820106146748 Effective search space used: 820106146748 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)