BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0147.0006.p (447 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KBY3.1 B3KBY3_9BACI Sensor protein EC=2.7.13.3 278 1e-72 C0ZIU0.1 C0ZIU0_BREBN Two-component sensor histidine kinase EC=2... 275 5e-72 B1HQU6.1 B1HQU6_LYSSC Sensor protein EC=2.7.13.3 265 1e-68 A3IBS5.1 A3IBS5_9BACI Sensor protein EC=2.7.13.3 263 2e-68 A9VMP1.1 A9VMP1_BACWK Sensor protein EC=2.7.13.3 258 9e-67 >B3KBY3.1 B3KBY3_9BACI Sensor protein EC=2.7.13.3 Length = 455 Score = 278 bits (710), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 162/451 (35%), Positives = 252/451 (55%), Gaps = 21/451 (4%) Query: 1 VLTFLGVVIVSLLSGFFVQSYFYKSHIGAIVEEKMIGNAQMIIQLYKKLAPKDAKAFAEV 60 VLTFL VI + FF+ ++ +K + + + Q ++++YK L ++A F Sbjct: 10 VLTFLVSVIGGTILSFFMSTWMFKEQLNENAQITLRNFGQDVVRIYKTLPLREADLFVSE 69 Query: 61 SNSMPFYKIRFYDSLGTL-----LN---PGSAAPDRQKDQPYLQQVLKQNKIYRNGSSED 112 + Y +R Y++ G LN P D+ LQQV+ + + ++ Sbjct: 70 MKQLDSYYVRIYEATGQFQAYGKLNGHKPAEVTMDK------LQQVI-EGGVVQDTQKGI 122 Query: 113 DEITVGLPFALNGSPHAL---LVTTQTVFFLDEIDSLIRYQQLFTLGLGSILVLIAARYM 169 + +GLP A+ ++ + F+ + S+ L T GS+L+LIA+ Y+ Sbjct: 123 ATVLLGLPLKTETGTKAMFLEMLAPPSTSFVVKWGSIFATSSLIT---GSLLILIASIYL 179 Query: 170 VRPLRKLTHATQRMARGDFNVGLSTKRRDEIGQLTLSFNAMAAELGKLDMLRRRFVSDVS 229 VRP++KLT AT+R+A GDF+V L+ K+ E+G L SF M EL +L+ LRR FV++VS Sbjct: 180 VRPIKKLTKATRRIAAGDFSVKLNIKQTSELGTLARSFEDMMHELQQLEQLRREFVTNVS 239 Query: 230 HEIQSPLTSIKGYTRVLKIKSMDGKTRMQMLNIIDEXXXXXXXXXXXXXXXTSLEHEHAK 289 HE+QSPLTSI GY + LK ++ R + L+II + LE + + Sbjct: 240 HEVQSPLTSISGYAQALKQVNLSDDERRRYLDIIIAEAKRMSKMSDSLLKLSLLESQSQQ 299 Query: 290 PDLQKFRLDEQLRKAAIRLEPQWSARNLDMQLMLEPITIVADEDKMNQVWNNLLGNCIKF 349 P L LDEQ+R+ + L+PQW+AR++ +L L P+ + AD D++NQVW N++GN IKF Sbjct: 300 PGLSTLSLDEQIRRVIVALQPQWAARSIQFELDLLPVKVTADHDQLNQVWTNIIGNSIKF 359 Query: 350 TADHGKIMVESFKKGESAVVRMTDNGIGIPEEEISQIFKPFYKVDTARKRNISGNGIGLS 409 + D G I V + + VR++D GIGI E+ +IF+ F+K D +R R G+G+GL+ Sbjct: 360 SKDGGVINVSIKQDMNNVTVRISDTGIGISLEDQKRIFERFFKTDRSRSRKYEGSGMGLA 419 Query: 410 IVKRIVDLHHGKIEVSSRLGNGTSFSISLPL 440 IVK+IV LH G I V S G G +F ++LP+ Sbjct: 420 IVKQIVSLHQGDIRVESEPGQGATFIVTLPI 450 >C0ZIU0.1 C0ZIU0_BREBN Two-component sensor histidine kinase EC=2.7.3.- Length = 469 Score = 275 bits (704), Expect = 5e-72, Method: Compositional matrix adjust. Identities = 160/453 (35%), Positives = 251/453 (55%), Gaps = 19/453 (4%) Query: 1 VLTFLGVVIVSLLSGFFVQSYFYKSHIGAIVEEKMIGNAQMIIQLYKKLAPKDAKAFAEV 60 VLTF+ +V++S GF + + +Y+ ++ A E+K++ Q +I LY+ + D AF Sbjct: 9 VLTFVAIVLISGTLGFLLANEYYQRNLRAYNEQKIMSIGQQMIDLYEHKSSLDLPAFMTH 68 Query: 61 SNSMPFYKIRFYDSLGTLLNPGSAAPDRQKDQPYLQQVLKQNKIYRNGSSEDDEI----- 115 ++ F ++ D G G+ D+Q + +Q+VL + YR + E + Sbjct: 69 VANLNF-QLYLVDENGAASQFGAPFRDQQIEPAIIQKVLA-GETYRGITEEQHGLFVTGF 126 Query: 116 -------TVGLPFALNGSPHALLVTTQTVFFLDEIDSL--IRYQQLFTLGLGSILVLIAA 166 ++GLP G +AL V E+ + + +F L L +L+LI Sbjct: 127 FENTLTNSIGLPLTAEGKKYALFVRPNIEQQFGEVHIMFALLLAAMFVLSL--VLILIFT 184 Query: 167 RYMVRPLRKLTHATQRMARGDFNVGLSTKRRDEIGQLTLSFNAMAAELGKLDMLRRRFVS 226 RY+V+P+ KL+HAT+++A G++++ L RRDEIG L + F M L +LD +R+ FVS Sbjct: 185 RYLVKPIEKLSHATKKLAEGEYDIHLDISRRDEIGDLAMHFARMTESLKQLDEMRQEFVS 244 Query: 227 DVSHEIQSPLTSIKGYTRVLKIKSMDGKTRMQMLNIIDEXXXXXXXXXXXXXXXTSLEHE 286 +VSHEIQSPLTSI+G+++ ++ + + R L II+E SL+ E Sbjct: 245 NVSHEIQSPLTSIQGFSQAIRSGGVTNEQRETYLTIIEEESRRLSSLSKQLLTLASLDKE 304 Query: 287 HAKPDLQKFRLDEQLRKAAIRLEPQWSARNLDMQLMLEPITIVADEDKMNQVWNNLLGNC 346 + +FRLDEQ+R+ + LE QW + L M+L L IV D+ +NQVW NL+ N Sbjct: 305 TGLYEPTRFRLDEQIRQVLLVLEHQWQQKKLTMELTLPETFIVGDKQLLNQVWMNLIANS 364 Query: 347 IKFTADHGKIMVESFKKGESAVVRMTDNGIGIPEEEISQIFKPFYKVDTARKRNISGNGI 406 IKFT G I + +K VV + D GIG+ EEE +F FYK D +R R +G+G+ Sbjct: 365 IKFTPKAGSIYI-MIQKDTRIVVTIRDTGIGMSEEEQEHVFDRFYKGDKSRNREATGSGL 423 Query: 407 GLSIVKRIVDLHHGKIEVSSRLGNGTSFSISLP 439 GLSIV++I+ + G I + SR+G GT+ ++SLP Sbjct: 424 GLSIVQKILQVAKGGIHIQSRIGEGTTVTVSLP 456 >B1HQU6.1 B1HQU6_LYSSC Sensor protein EC=2.7.13.3 Length = 443 Score = 265 bits (676), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 150/441 (34%), Positives = 245/441 (55%), Gaps = 4/441 (0%) Query: 1 VLTFLGVVIVSLLSGFFVQSYFYKSHIGAIVEEKMIGNAQMIIQLYKKLAPKDAKAFAEV 60 +LTFL VI + FFV ++ +K + ++ ++ Q I+ ++ + ++A Sbjct: 1 MLTFLVAVIGGTVVSFFVATWLFKDKLNEYLQIPLLNFGQDIVLIFDTMPFQEADHLLSQ 60 Query: 61 SNSMPFYKIRFYDSLGTLLNPGSAAPD--RQKDQPYLQQVLKQNKIYRNGSSEDDEITVG 118 N + Y + YD G + G A D + + ++ VL+ + N + VG Sbjct: 61 MNQLKSYDVYVYDEAGGMKAYGDAQSDTLNKVTKKQVRDVLEGKVVQVNPNVSSG--LVG 118 Query: 119 LPFALNGSPHALLVTTQTVFFLDEIDSLIRYQQLFTLGLGSILVLIAARYMVRPLRKLTH 178 +P + A+ + + V + +LI + L +GS++ LIAA ++VRP++KLT Sbjct: 119 MPLTTDKGTKAMFIEPKAVSSVSFALTLILNFSTYALVIGSVVFLIAAMFLVRPIKKLTK 178 Query: 179 ATQRMARGDFNVGLSTKRRDEIGQLTLSFNAMAAELGKLDMLRRRFVSDVSHEIQSPLTS 238 AT+ +A GDFNV L+ K+ E+G L SF MA++L +L+ +R+ FVS+VSHE+QSPLTS Sbjct: 179 ATRHIAGGDFNVELNIKQSGELGVLARSFEEMASDLQQLEQMRKEFVSNVSHEVQSPLTS 238 Query: 239 IKGYTRVLKIKSMDGKTRMQMLNIIDEXXXXXXXXXXXXXXXTSLEHEHAKPDLQKFRLD 298 I GY LK + + + + L+II + LE + L LD Sbjct: 239 ISGYALALKQVDLTIEEKNRYLDIIMAEAQRMSKMSDSLLKLSLLESKAPPMQLVSLSLD 298 Query: 299 EQLRKAAIRLEPQWSARNLDMQLMLEPITIVADEDKMNQVWNNLLGNCIKFTADHGKIMV 358 EQ+R+ + ++PQW A+N+ L L+ + ++AD D++NQVW NLL N IKF+ D I + Sbjct: 299 EQIRRVIVAIQPQWMAKNIHFNLQLQSVYVMADYDQLNQVWTNLLTNSIKFSKDGDTIKI 358 Query: 359 ESFKKGESAVVRMTDNGIGIPEEEISQIFKPFYKVDTARKRNISGNGIGLSIVKRIVDLH 418 ++ +VR+TD GIGI +E+ ++F+ F+K D + R G+G+GL+IVK+IV LH Sbjct: 359 SMSQEAHHVLVRITDTGIGISQEDQKRVFERFFKADRSHSRKYEGSGMGLAIVKQIVSLH 418 Query: 419 HGKIEVSSRLGNGTSFSISLP 439 G + V S L GT+F ++LP Sbjct: 419 KGDVRVESELEQGTTFIVTLP 439 >A3IBS5.1 A3IBS5_9BACI Sensor protein EC=2.7.13.3 Length = 452 Score = 263 bits (673), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 151/444 (34%), Positives = 243/444 (54%), Gaps = 8/444 (1%) Query: 1 VLTFLGVVIVSLLSGFFVQSYFYKSHIGAIVEEKMIGNAQMIIQLYKKLAPKDAKAFAEV 60 VLTFL VI + FFV ++ +K + ++ ++ Q I+ ++ + ++A Sbjct: 10 VLTFLVAVIGGTVVSFFVATWLFKDKLNEQLQIPLLNFGQDIVLIFDTMPFQEADNLLSQ 69 Query: 61 SNSMPFYKIRFYDSLGTLLNPGSAAPDRQKD--QPYLQQVLKQNKIYRNGSSEDDEITVG 118 N + Y + YD G + G A D+ D + ++ VL + N + VG Sbjct: 70 MNQLKSYDVYVYDEAGKMKAYGDAPSDKLVDVTKTQVRDVLDGKVVQVNPNVSSG--LVG 127 Query: 119 LPFALNGSPHALLVTTQTVFFLDEIDSLIRYQQLFTLGLGSILVLIAARYMVRPLRKLTH 178 +P + A+ + + V ++I + L +GS++ LIAA ++VRP++KLT Sbjct: 128 MPLTTDKGTKAMFIEPKAVSSASFALTVILNFSTYALVIGSVVFLIAAMFLVRPIKKLTK 187 Query: 179 ATQRMARGDFNVGLSTKRRDEIGQLTLSFNAMAAELGKLDMLRRRFVSDVSHEIQSPLTS 238 AT+ +A GDFNV L+ K+ E+G L SF MA +L +L+ +R+ FVS+VSHE+QSPLTS Sbjct: 188 ATRHIAGGDFNVELNIKQSGELGVLARSFEEMAYDLQQLEQMRKEFVSNVSHEVQSPLTS 247 Query: 239 IKGYTRVLKIKSMDGKTRMQMLNIIDEXXXXXXXXXXXXXXXTSLEHEHAKPDLQ--KFR 296 I GY LK + + + + L+II E P +Q Sbjct: 248 ISGYALALKQVDLTDEEKNRYLDII--MAEAQRMSKMSDSLLKLSLLESKAPPMQPVSLS 305 Query: 297 LDEQLRKAAIRLEPQWSARNLDMQLMLEPITIVADEDKMNQVWNNLLGNCIKFTADHGKI 356 LDEQ+R+ + ++PQW A+N+ L L+ + ++AD D++NQVW NLL N IKF+ D I Sbjct: 306 LDEQIRRVIVAIQPQWMAKNIHFNLQLQSMYVMADYDQLNQVWTNLLTNSIKFSKDGDTI 365 Query: 357 MVESFKKGESAVVRMTDNGIGIPEEEISQIFKPFYKVDTARKRNISGNGIGLSIVKRIVD 416 + ++ +VR+TD GIGI +E+ ++F+ F+K D + G+G+GL+IVK+IV Sbjct: 366 KISMSQEAHHVLVRITDTGIGISQEDQKRVFERFFKADRSHSPKYEGSGMGLAIVKQIVS 425 Query: 417 LHHGKIEVSSRLGNGTSFSISLPL 440 LH G + V S LG GT+F ++LP+ Sbjct: 426 LHKGDVRVESELGQGTTFIVTLPI 449 >A9VMP1.1 A9VMP1_BACWK Sensor protein EC=2.7.13.3 Length = 455 Score = 258 bits (659), Expect = 9e-67, Method: Compositional matrix adjust. Identities = 156/456 (34%), Positives = 239/456 (52%), Gaps = 31/456 (6%) Query: 1 VLTFLGVVIVSLLSGFFVQSYFYKSHIGAIVEEKMIGNAQMIIQLYKKLAPKDAKAFAEV 60 VLTFL +I + F V ++ ++ + + + Q I+++YK ++A F Sbjct: 10 VLTFLVSIIGGTIISFLVSTWIFEDKLNENAQINLRNFGQDIVRIYKTFPLREADLFVSE 69 Query: 61 SNSMPFYKIRFYDSLGTLLNPGSAAPDRQKDQPYLQQVLKQNKIYRNGSSEDD-----EI 115 + Y IR Y++ G + G K P + LK K+ G +D + Sbjct: 70 MKQLDSYYIRIYEATGQFKSYGKLHG--HKPAPVTMEQLK--KVLDGGVVQDTPNGIATV 125 Query: 116 TVGLPFALN-----------GSPHALLVTTQTVFFLDEIDSLIRYQQLFTLGLGSILVLI 164 +GLP P A VT + F +L GS+L+L+ Sbjct: 126 LLGLPLKTEMGTKAIFLEALAPPSASFVTKWALVF-----------ATCSLIAGSLLILV 174 Query: 165 AARYMVRPLRKLTHATQRMARGDFNVGLSTKRRDEIGQLTLSFNAMAAELGKLDMLRRRF 224 A+ ++VRP++KLT AT+R+A GDFNV L+ K+ E+G L SF M +L +L+ +RR F Sbjct: 175 ASVFLVRPIKKLTKATKRIASGDFNVKLNIKQTSELGTLARSFEEMMHDLQQLEQMRREF 234 Query: 225 VSDVSHEIQSPLTSIKGYTRVLKIKSMDGKTRMQMLNIIDEXXXXXXXXXXXXXXXTSLE 284 V++VSHE+QSPLTSI GY VLK + R + L+II + LE Sbjct: 235 VTNVSHEVQSPLTSISGYALVLKQVDLSEYERSRYLDIIIAEAKRMSKMSDNLLKLSFLE 294 Query: 285 HEHAKPDLQKFRLDEQLRKAAIRLEPQWSARNLDMQLMLEPITIVADEDKMNQVWNNLLG 344 + + L LDEQ+R+ + L+PQWSAR++ +L L+ + + AD D +NQVW N+L Sbjct: 295 SQSKQLRLVTLSLDEQIRRIIVALQPQWSARDIHFELDLQTVKVTADHDLLNQVWTNILR 354 Query: 345 NCIKFTADHGKIMVESFKKGESAVVRMTDNGIGIPEEEISQIFKPFYKVDTARKRNISGN 404 N IKF+ D G I V + ++ + ++D GIGI ++ +IF F+K D + R G+ Sbjct: 355 NSIKFSEDAGVINVSIKQDIKNVTILISDTGIGIHLDDQKRIFDRFFKADRSHSRKYDGS 414 Query: 405 GIGLSIVKRIVDLHHGKIEVSSRLGNGTSFSISLPL 440 G+GL+IVK+IV LH G I V S G GT+F ++LP+ Sbjct: 415 GMGLAIVKQIVSLHQGDIRVKSEPGQGTTFIVTLPI 450 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.137 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,391,229,873 Number of extensions: 92778477 Number of successful extensions: 338784 Number of sequences better than 1.0e-05: 28012 Number of HSP's gapped: 308402 Number of HSP's successfully gapped: 28454 Length of query: 447 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 308 Effective length of database: 1,751,175,118 Effective search space: 539361936344 Effective search space used: 539361936344 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 133 (55.8 bits)