BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0145.0003.p (336 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B0K7P8.1 B0K7P8_THEP3 Transcriptional regulator, LacI family 376 e-102 B0K6E2.1 B0K6E2_THEPX Regulatory protein, LacI 375 e-102 B8DZA4.1 B8DZA4_DICTD Transcriptional regulator, LacI family 364 7e-99 B5YAX3.1 B5YAX3_DICT6 Transcriptional regulator 360 1e-97 Q65D68.1 Q65D68_BACLD Putative uncharacterized protein 286 1e-75 >B0K7P8.1 B0K7P8_THEP3 Transcriptional regulator, LacI family Length = 324 Score = 376 bits (965), Expect = e-102, Method: Compositional matrix adjust. Identities = 183/325 (56%), Positives = 237/325 (72%), Gaps = 1/325 (0%) Query: 12 MPTIKDVALKAGVSATTVSRVLNNRGYLSEALKQRVYSAMEELNYRPNELARSLSRSRSN 71 MPTIKDVA KAGV+ TTVSRVLNNRGY+SE +++VY AM+ELNY+PNELARSL R +S Sbjct: 1 MPTIKDVAKKAGVTVTTVSRVLNNRGYISEVTRKKVYEAMKELNYQPNELARSLYRKKSY 60 Query: 72 IIGLIIPLVSLPFFSELTSYIEEHAYLNGYKLLLCNSQQDKIKELEYIDMLRSSRVDGII 131 +IGL+IP V+ PFF+ELT YIE +AY GYK+LLCNS QD KE EYIDML+ +VDGII Sbjct: 61 LIGLLIPNVAHPFFAELTGYIEYYAYQEGYKILLCNSGQDSSKEKEYIDMLKRHQVDGII 120 Query: 132 MGSHTLEVEAYRQMNLPLVTFDRQISPGIPFVCSDNYTGGQLATTLLIEKGCRKLAHIGG 191 +GSHTLE E Y + LP+V DR S IP+V SDNY GG LAT LLI+KGC+K+AHI G Sbjct: 121 IGSHTLEAEQYLNVKLPIVAIDRYYS-NIPYVASDNYKGGILATKLLIQKGCKKIAHISG 179 Query: 192 HPELNLLSNLRYEAFVETARLAGIWHTSLHTDNNSFDVLAYERLLEQLFREHSGIDGIFA 251 LN +N RY+AF E A + + + T N F++ Y++++ LF+EH IDGIFA Sbjct: 180 PLILNTPANNRYKAFKEVATQENVEYFVVETKLNRFEIEEYKKIVRGLFKEHPDIDGIFA 239 Query: 252 GSDLIAAFALKACRERGRRVPADVRIVGYDGTALCSLNHPSITTIRQPMEEMGRLAVELI 311 DLIAA + +E +++P D++IVGYD + +L PS+TT+RQP++E+ R A+ELI Sbjct: 240 SGDLIAASVISVAKELNKKIPQDLKIVGYDDINVANLVVPSLTTVRQPIKEIARKAIELI 299 Query: 312 LKQVEGMSVPSANILPVKLQEGSTT 336 L+Q++G V NILP+ L E TT Sbjct: 300 LRQIDGEKVEKENILPITLIERETT 324 >B0K6E2.1 B0K6E2_THEPX Regulatory protein, LacI Length = 324 Score = 375 bits (964), Expect = e-102, Method: Compositional matrix adjust. Identities = 184/325 (56%), Positives = 237/325 (72%), Gaps = 1/325 (0%) Query: 12 MPTIKDVALKAGVSATTVSRVLNNRGYLSEALKQRVYSAMEELNYRPNELARSLSRSRSN 71 MPTIKDVA KAGV+ TTVSRVLNNRGY+SE +++VY AM+ELNY+PNELARSL R +S Sbjct: 1 MPTIKDVAKKAGVTVTTVSRVLNNRGYISEVTRKKVYEAMKELNYQPNELARSLYRKKSY 60 Query: 72 IIGLIIPLVSLPFFSELTSYIEEHAYLNGYKLLLCNSQQDKIKELEYIDMLRSSRVDGII 131 +IGL+IP VS PFF+ELT YIE +AY GYK+LLCNS QD KE YIDML+ +VDGII Sbjct: 61 LIGLLIPNVSHPFFAELTGYIEYYAYQEGYKILLCNSGQDSSKEKGYIDMLKRHQVDGII 120 Query: 132 MGSHTLEVEAYRQMNLPLVTFDRQISPGIPFVCSDNYTGGQLATTLLIEKGCRKLAHIGG 191 +GSHTLE E Y + LP+V DR S IP+V SDNY GG LAT LLI+KGC+K+AHI G Sbjct: 121 IGSHTLEAEQYLNVKLPIVAIDRYYS-NIPYVASDNYKGGILATKLLIQKGCKKIAHISG 179 Query: 192 HPELNLLSNLRYEAFVETARLAGIWHTSLHTDNNSFDVLAYERLLEQLFREHSGIDGIFA 251 LN +N RY+AF E A + + + T N F++ Y++++ LF+EH IDGIFA Sbjct: 180 PLILNTPANNRYKAFKEVATQENVEYFVVETKLNRFEIEEYKKIVRGLFKEHPDIDGIFA 239 Query: 252 GSDLIAAFALKACRERGRRVPADVRIVGYDGTALCSLNHPSITTIRQPMEEMGRLAVELI 311 SDLIAA + +E +++P D++IVGYD + +L PS+TT+RQP++E+ R A+ELI Sbjct: 240 SSDLIAASVISVAKELNKKIPQDLKIVGYDDINVANLVVPSLTTVRQPIKEIARKAIELI 299 Query: 312 LKQVEGMSVPSANILPVKLQEGSTT 336 L+Q++G V NILP+ L E TT Sbjct: 300 LRQIDGEKVEKENILPITLIERETT 324 >B8DZA4.1 B8DZA4_DICTD Transcriptional regulator, LacI family Length = 325 Score = 364 bits (934), Expect = 7e-99, Method: Compositional matrix adjust. Identities = 171/325 (52%), Positives = 235/325 (72%) Query: 12 MPTIKDVALKAGVSATTVSRVLNNRGYLSEALKQRVYSAMEELNYRPNELARSLSRSRSN 71 M +I+DVA +AGV+ TTVSRVLNNRGY+SE +++VY AMEELNY+PNELAR+L R RS Sbjct: 1 MASIRDVAKRAGVTVTTVSRVLNNRGYISEETRKKVYKAMEELNYQPNELARALYRKRSY 60 Query: 72 IIGLIIPLVSLPFFSELTSYIEEHAYLNGYKLLLCNSQQDKIKELEYIDMLRSSRVDGII 131 IGLIIP VS PFF E+ YIE +AYL GYK+LLCNS D+ KE EYI+ML+ +VDGII Sbjct: 61 FIGLIIPDVSHPFFGEVAKYIEYYAYLRGYKILLCNSYLDEKKEKEYINMLKRHQVDGII 120 Query: 132 MGSHTLEVEAYRQMNLPLVTFDRQISPGIPFVCSDNYTGGQLATTLLIEKGCRKLAHIGG 191 MGSHTL+VE Y+++NLP+V DR +S IP+V SDNY G +AT LLIEKGCR LAHI G Sbjct: 121 MGSHTLDVEDYKKVNLPIVALDRVLSEDIPYVTSDNYRGAVMATNLLIEKGCRFLAHISG 180 Query: 192 HPELNLLSNLRYEAFVETARLAGIWHTSLHTDNNSFDVLAYERLLEQLFREHSGIDGIFA 251 +LN +N RY F+ + H + T N FD+ Y+ ++ QLF+++ IDG+FA Sbjct: 181 PLQLNTPANDRYYGFMHVVSQRSVKHVVVETRLNKFDINEYKDIVSQLFKKYPEIDGVFA 240 Query: 252 GSDLIAAFALKACRERGRRVPADVRIVGYDGTALCSLNHPSITTIRQPMEEMGRLAVELI 311 SDLIAA ++ + G++VP +++VG+D + S+ PSITT+RQ ++M + A++LI Sbjct: 241 SSDLIAAVVIRVAEDFGKKVPESLKVVGFDDVNIASIMKPSITTVRQYKDKMAQKAIDLI 300 Query: 312 LKQVEGMSVPSANILPVKLQEGSTT 336 + ++EG +V +N++P+ L E +T Sbjct: 301 INKIEGNNVEVSNVIPIDLIEREST 325 >B5YAX3.1 B5YAX3_DICT6 Transcriptional regulator Length = 328 Score = 360 bits (923), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 172/325 (52%), Positives = 232/325 (71%) Query: 12 MPTIKDVALKAGVSATTVSRVLNNRGYLSEALKQRVYSAMEELNYRPNELARSLSRSRSN 71 MP++KDVA +AGVS TTVSRVLNNRGY+SE +++VY AMEELNY+PNE+AR+L + RS Sbjct: 1 MPSLKDVAKRAGVSPTTVSRVLNNRGYISEETRRKVYKAMEELNYQPNEIARALFKKRSY 60 Query: 72 IIGLIIPLVSLPFFSELTSYIEEHAYLNGYKLLLCNSQQDKIKELEYIDMLRSSRVDGII 131 +GLIIP +S PFF+E+T YIE +AYL GYK+L+CNS D KE EYI ML+ +VDGII Sbjct: 61 FLGLIIPDISHPFFAEITKYIEYYAYLKGYKVLICNSYLDGHKEKEYIKMLKRHQVDGII 120 Query: 132 MGSHTLEVEAYRQMNLPLVTFDRQISPGIPFVCSDNYTGGQLATTLLIEKGCRKLAHIGG 191 MGSHTL VE Y+ +NLP+V DR IS IP + SDN+TG +AT LLIE+GC+ LAHI G Sbjct: 121 MGSHTLNVEDYKSINLPIVALDRYISEDIPCITSDNFTGAIMATKLLIERGCKYLAHISG 180 Query: 192 HPELNLLSNLRYEAFVETARLAGIWHTSLHTDNNSFDVLAYERLLEQLFREHSGIDGIFA 251 ELN +N RY F++ R GI H + T N F++ Y+++++ LF +H IDGIFA Sbjct: 181 PLELNTPANDRYYGFLKVVREKGIKHVVVETKLNKFEIEEYQKIIKDLFEKHPQIDGIFA 240 Query: 252 GSDLIAAFALKACRERGRRVPADVRIVGYDGTALCSLNHPSITTIRQPMEEMGRLAVELI 311 SDLIAA ++ + VP D+++VG+D L SL PS+TTIRQ ++M + +E++ Sbjct: 241 SSDLIAATVIRMADRFKKNVPKDLKVVGFDDIGLASLLRPSLTTIRQDKDKMAQKLIEVL 300 Query: 312 LKQVEGMSVPSANILPVKLQEGSTT 336 + ++EG + S ILP+ L E +T Sbjct: 301 IDKIEGKNAESKYILPISLIEREST 325 >Q65D68.1 Q65D68_BACLD Putative uncharacterized protein Length = 324 Score = 286 bits (733), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 152/330 (46%), Positives = 207/330 (62%), Gaps = 14/330 (4%) Query: 13 PTIKDVALKAGVSATTVSRVLNNRGYLSEALKQRVYSAMEELNYRPNELARSLSRSRSNI 72 P+I DVA KAGVS TTVSRVLNNRGY+SE K++VY AMEE+NY PN+LARSL R R+++ Sbjct: 3 PSIHDVAKKAGVSPTTVSRVLNNRGYISEKTKEKVYKAMEEINYFPNDLARSLFRKRTHL 62 Query: 73 IGLIIPLVSLPFFSELTSYIEEHAYLNGYKLLLCNSQQDKIKELEYIDMLRSSRVDGIIM 132 IGLIIP S PFF EL +IE GYKLLLCNS K KE +Y++ML ++VDG+I Sbjct: 63 IGLIIPNSSNPFFGELAFHIESICAAMGYKLLLCNSLNRKDKEEKYLEMLMRNQVDGVIA 122 Query: 133 GSHTLEVEAYRQMNLPLVTFDRQISPGIPFVCSDNYTGGQLATTLLIEKGCRKLAHIGGH 192 ++ + Y + NLP+V D +S IP + SDNY GG+ AT LLI KGCR + HI G Sbjct: 123 VTYNRGILNYHRQNLPIVAIDHYLSETIPVIGSDNYDGGRKATELLIAKGCRHIIHINGP 182 Query: 193 PELNLLSNLRYEAFVETARLAG----IWHTSLHTDNNSFDVLAYERLLEQLFREHSGIDG 248 EL +NLR +A+ + R G + H + Y ++ +LF E DG Sbjct: 183 IELKTPANLRRKAYEDVMRQHGRQPITYEVPFHQN--------YREIISKLFDEQPAADG 234 Query: 249 IFAGSDLIAAFALKACRERGRRVPADVRIVGYDGTALCSLNHPSITTIRQPMEEMGRLAV 308 IFA DL+AA + ++R + +P ++++GYDGT P +TTI+QP+E + + A+ Sbjct: 235 IFASDDLMAATVITEAKKRRKDIPGQLKVIGYDGTEAVQSILPELTTIQQPIELISKTAI 294 Query: 309 ELILKQVEGM--SVPSANILPVKLQEGSTT 336 E++ K +EG +P LPV+L EG TT Sbjct: 295 EILSKAIEGEFDDLPLETYLPVQLLEGETT 324 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.136 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,910,796,910 Number of extensions: 77157128 Number of successful extensions: 240317 Number of sequences better than 1.0e-05: 9462 Number of HSP's gapped: 226854 Number of HSP's successfully gapped: 9518 Length of query: 336 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 200 Effective length of database: 1,779,438,163 Effective search space: 355887632600 Effective search space used: 355887632600 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 131 (55.1 bits)