BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0145.0001.p (988 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A0Q1B8.1 A0Q1B8_CLONN Diguanylate cyclase/phosphodiesterase doma... 574 e-161 B8I783.1 B8I783_CLOCE Diguanylate cyclase/phosphodiesterase 459 e-127 A1ATC4.1 A1ATC4_PELPD Periplasmic sensor diguanylate cyclase/pho... 387 e-105 B0CAI7.1 B0CAI7_ACAM1 Diguanylate cyclase/phosphodiesterase with... 387 e-105 B9LZ98.1 B9LZ98_GEOSF Diguanylate cyclase/phosphodiesterase with... 379 e-102 >A0Q1B8.1 A0Q1B8_CLONN Diguanylate cyclase/phosphodiesterase domain 2 Length = 961 Score = 574 bits (1479), Expect = e-161, Method: Compositional matrix adjust. Identities = 343/992 (34%), Positives = 521/992 (52%), Gaps = 78/992 (7%) Query: 8 LKVFQSWRMPLLLVAMLSAFLFPALTVKAEGQPPQNVLVLHSYQKGFAWTDEQSGGIEER 67 LK+F + + + V M ++ +L K NVL+L+SY +GF WT GI + Sbjct: 14 LKIF-IYFIIVFCVFMCKTYIVYSLDYK-------NVLILNSYDEGFKWTRHMERGIYDV 65 Query: 68 LKGAENAPVIYTEYMDWKRYPSQENLRQLYQTIKLKYHNIHVDAIITTDDAALSFALKYR 127 L + ++ EYMD K + E + L + KY N +D II D+ AL+F L + Sbjct: 66 LNNQYDIH-LFHEYMDTKNINNAEYIDMLTKLYIKKYENKKIDLIICCDNDALNFILSSK 124 Query: 128 QEILDDAPIIFSGVNELGVENIPDKRKITGVIEKIDPTRTIQMALQINPSIRKVYVVFDN 187 + L+ P++F G+NE + I +K+ TGV+EKID TI + P+ + + VV D+ Sbjct: 125 IKFLNSCPLVFCGINEFSDDLIKNKKNCTGVVEKIDVDSTISSIFTMQPNTKNIVVVTDS 184 Query: 188 SESGLSTGRLVMDQIASLNQGLELIPLNRLSSEQIIHTVSGLSSDSIVLMTTYYSDSTGR 247 S +G S I+ + + + ++ ++ + + GLSSD+++L + D Sbjct: 185 STTGKSNEESAKKVISKYKERVNVYFCKDITQKEFYNKLKGLSSDTVILYIGQFRDDNYD 244 Query: 248 IIEFERFASELGRSSSVPVYHLYDFALNHGAFGGSLISGKIQGQTSAELALRILQGERAD 307 +I F + + ++ P+Y +DF GG +ISG QG + +A +IL+G Sbjct: 245 VIPFSK-SGKILEKCKYPIYVCWDFLFGKNVVGGKVISGYDQGLVAGNMASKILRGINVK 303 Query: 308 ELPIVTDSTMRIVYDYNELRHFGIPLNKLPEGSEIINKPFSFYETYRTLVLGISXXXXXX 367 +PI+ + V++YNEL I LN LP+ S I+N+P+SF Y+ ++ +S Sbjct: 304 NVPIMRNCPSNYVFNYNELVKHNIKLNNLPKNSTIVNRPYSFIYEYKRYIVAVSSLIFIL 363 Query: 368 XXXXXXXXXXXXXXKRMRSH----------------LEKSNERFSLAAFGSDAVIWDVDM 411 KR+ S LEK +++ L GS+ IW+ D+ Sbjct: 364 TTFIIILSINIR--KRIESEKKLKENYIALEKSKETLEKGRQKYKLVVDGSNDAIWEWDI 421 Query: 412 STMIYYFSDSWYELLGYER-GEVNESHGGWREIVHPEDAEQEDRLRTQHLEGRSSYYYAE 470 + S+ + G + ++NE+ + +I+ ED ++ + L +Y E Sbjct: 422 KEDKLFMSNKLNIIKGSSKYTDINENKRYFSKIIKEEDYKKIIEKFKEILYKNENYIDVE 481 Query: 471 YRMRSKSGEYIWFQARGKVLRSAGGGYIRFAGSMVDVTDRKGYESKLQISYQELESTYEE 530 R+ + WF +GK LR G ++ AGS+ D+TDRK E+ +I Y Sbjct: 482 CRILDEFNYENWFNIKGKALRDGEGNVLKIAGSITDITDRK--EAIKKIEY--------- 530 Query: 531 LTALQDELMEQYNKVVENQELLQASEEKYRLLAYNDVLSGLPNRLSLSEELTDFIE--KH 588 LAYND L+GLPNR++ S ++ I+ K Sbjct: 531 -------------------------------LAYNDSLTGLPNRVAYSRDIYGIIQNVKK 559 Query: 589 PGGQAALFFLDIDNFKYINDTMGHTFGDELLVKAGERLLELSDGRCRHFRFGGDEFVILI 648 A+ FLDIDNFK +NDT+GH +G+ELL K +R+ + R +R GGDEF+I+ Sbjct: 560 DNKIGAIMFLDIDNFKNVNDTLGHDYGNELLKKVNKRISNILTEDERFYRLGGDEFIIV- 618 Query: 649 KEVDRYAE--VIYYAESLVQGFSAPFELDASSVHISISIGIASYPENGTDAGELLKNADI 706 + Y E + A+++++ FS F + ++ ++S+GI+ +P++ D LLK AD Sbjct: 619 -QCGSYNEKDIELLADNILKLFSKSFIVKNEHIYTTVSLGISFFPKDSCDQSVLLKYADT 677 Query: 707 AMYKAKEAGKGTYVVYGEEMQQHFDERMIVEHHLRNAIANNELSLQYQPLVDTGTGRIWG 766 AMY AK GK Y++Y +EM + R +E LR+AI EL L +QP V+ TG I G Sbjct: 678 AMYSAKNLGKSKYLIYNKEMSSNLIRRSQLEEGLRHAIERKELKLVFQPQVNANTGEIKG 737 Query: 767 FEALIRWNNPVLGIVSPLSFITIAEDCRLIVPIGEWVLRKACRFMKELQAQGYEGYHISV 826 E L+RWN+ G VSP FI IAE LI IGEWVLR++C K+ Q + + ISV Sbjct: 738 VEVLLRWNSEKFGFVSPSEFIVIAEKSGLINSIGEWVLRESCLKRKQWQIENLKDITISV 797 Query: 827 NISVVQLMLDDFTDMVLAVLEDTGLAPEYLELEITESIFMESFEAVSSKLEPLKQRGIGI 886 N+SV+QL DDF + + +LE T L PE LELEITES+ MES E L ++ G+ I Sbjct: 798 NVSVIQLQQDDFIEKLKEILEKTKLPPECLELEITESVMMESKETNLDILNSIRDIGVKI 857 Query: 887 ALDDFGTGYSSLSYLKQLPITTLKIDKSFIDSID-TPNNMSLASSIVTIGHDMGLNVTAE 945 ALDDFGTGYSSLSYLK LPI +K+DKSFID+I N+ + I+ + H +GLNV AE Sbjct: 858 ALDDFGTGYSSLSYLKMLPINKIKLDKSFIDTIHINKNDKFIVEGIIDLAHKIGLNVIAE 917 Query: 946 GVETQEQLAFLEQTSCDKIQGYFISRPIPQKE 977 GVE EQL L + +CD+IQGY+ S+P+ + E Sbjct: 918 GVELNEQLDVLCEANCDEIQGYYFSKPVEEFE 949 >B8I783.1 B8I783_CLOCE Diguanylate cyclase/phosphodiesterase Length = 856 Score = 459 bits (1180), Expect = e-127, Method: Compositional matrix adjust. Identities = 229/469 (48%), Positives = 313/469 (66%), Gaps = 1/469 (0%) Query: 511 KGYESKLQISYQELESTYEELTALQDELMEQYNKVVENQELLQASEEKYRLLAYNDVLSG 570 + +L +S +EL TYEEL A +EL Q +++ Q+ L SEEKY +A +DVL+G Sbjct: 382 RNIRKQLYLSNEELTQTYEELVASDEELRHQLDEIRSIQKSLSQSEEKYNFMALHDVLTG 441 Query: 571 LPNRLSLSEELTDFIEKHPGGQAALFFLDIDNFKYINDTMGHTFGDELLVKAGERLLELS 630 LPNR SL E+ + F+ + G + L F+D+DNFKYINDTMGH FGDEL+ KAG+RL Sbjct: 442 LPNRRSLLEDSSRFLGINTGKKTVLLFIDMDNFKYINDTMGHEFGDELINKAGQRLKTAL 501 Query: 631 DGRCRHFRFGGDEFVILIKEVDRYAEVIYYAESLVQGFSAPFELDASSVHISISIGIASY 690 +R GGDEF++LI ++ E + ++Q F FE+ S +HI+ SIG A Y Sbjct: 502 KDLGTLYRLGGDEFILLIYNIENQFEAEDFMSQVLQSFKDEFEIGNSVLHITFSIGAALY 561 Query: 691 PENGTDAGELLKNADIAMYKAKEAGKGTYVVYGEEMQQHFDERMIVEHHLRNAIANNELS 750 P++G + +L+K ADIAMYKAKE GK YV+Y +M + F ERM +E L A+ NNE Sbjct: 562 PDHGNNIEDLIKCADIAMYKAKEQGKNRYVLYDRDMDKAFSERMTIEKLLHTAMDNNEFE 621 Query: 751 LQYQPLVDTGTGRIWGFEALIRWNNPVLGIVSPLSFITIAEDCRLIVPIGEWVLRKACRF 810 + YQP D + +I G EAL+RW + LG VSP+ FI +AED LI+P+GEWVL +AC F Sbjct: 622 VYYQPQFDLQSQKITGLEALLRWKSSELGNVSPIKFIKVAEDTHLIIPLGEWVLNQACAF 681 Query: 811 MKELQAQGYEGYHISVNISVVQLMLDDFTDMVLAVLEDTGLAPEYLELEITESIFMESFE 870 +KEL +G +G +SVNIS +Q++ FT ++ ++ L PE LELEITE+I +ESF Sbjct: 682 VKELHEKGLQGLTVSVNISTIQILQSGFTRKIIDIINSHKLNPECLELEITETILIESFT 741 Query: 871 AVSSKLEPLKQRGIGIALDDFGTGYSSLSYLKQLPITTLKIDKSFIDSIDT-PNNMSLAS 929 V KL LK+ GI IALDDFG GYSSL+YLKQLPI+TLKIDKSFIDS+ ++ Sbjct: 742 TVFRKLNKLKKMGIRIALDDFGKGYSSLNYLKQLPISTLKIDKSFIDSVSIDEEGRTITR 801 Query: 930 SIVTIGHDMGLNVTAEGVETQEQLAFLEQTSCDKIQGYFISRPIPQKEV 978 I+T+G +G+ + AEGVE EQL +L++ CD+IQGY S+P+P ++V Sbjct: 802 HIITLGKSLGMTIIAEGVEFNEQLEYLKKYHCDRIQGYLFSKPLPGEDV 850 Score = 348 bits (894), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 167/321 (52%), Positives = 226/321 (70%), Gaps = 3/321 (0%) Query: 39 QPPQNVLVLHSYQKGFAWTDEQSGGIEERLKGAENAPVIYTEYMDWKRYPSQENLRQLYQ 98 QP +N+L+LHSY +G AWT Q+ GI E + Y EYMDWK YP+ L L Sbjct: 40 QPKKNILILHSYNEGLAWTSNQNTGIIEMIDKEYPNTSTYVEYMDWKNYPTSNILSYLSD 99 Query: 99 TIKLKYHNIHVDAIITTDDAALSFALKYRQEILDDAPIIFSGVNELGVENIPDKRK-ITG 157 + KY H+D IITTDDAA FAL R++I DAPI+FSGVN+ V I K TG Sbjct: 100 YFEFKYTQKHIDLIITTDDAAFKFALLNRKQIFSDAPIVFSGVNQEDVSKIAKHYKNYTG 159 Query: 158 VIEKIDPTRTIQMALQINPSIRKVYVVFDNSESGLSTGRLVMDQIASLNQGLELIPLNRL 217 VIE IDPT T ++AL+INP+++KVYVVFDNSESGLSTGRLVMD++ ++N LE IP+N + Sbjct: 160 VIENIDPTETFRIALRINPNLKKVYVVFDNSESGLSTGRLVMDKVKAMN--LEPIPMNNM 217 Query: 218 SSEQIIHTVSGLSSDSIVLMTTYYSDSTGRIIEFERFASELGRSSSVPVYHLYDFALNHG 277 S +++ VS L + SIV TYYSD G+++EF + E+ + SSVP+YH YDF LN G Sbjct: 218 SFNELLKVVSKLDNTSIVFFATYYSDGNGKMLEFNLASREISKYSSVPLYHQYDFGLNKG 277 Query: 278 AFGGSLISGKIQGQTSAELALRILQGERADELPIVTDSTMRIVYDYNELRHFGIPLNKLP 337 AFGG ++SG++ G +A+LA+RIL+GE A ++ I++ R+V+DY +L+ F +P+ KLP Sbjct: 278 AFGGDMVSGRLCGNYAAKLAVRILKGESASDIKIISPKATRVVFDYEQLKRFEVPVWKLP 337 Query: 338 EGSEIINKPFSFYETYRTLVL 358 + +EIINKPFSF+ETY+ LV+ Sbjct: 338 KTAEIINKPFSFFETYKRLVV 358 >A1ATC4.1 A1ATC4_PELPD Periplasmic sensor diguanylate cyclase/phosphodiesterase Length = 876 Score = 387 bits (994), Expect = e-105, Method: Compositional matrix adjust. Identities = 201/418 (48%), Positives = 267/418 (63%), Gaps = 7/418 (1%) Query: 562 LAYNDVLSGLPNRLSLSEELTD--FIEKHPGGQAALFFLDIDNFKYINDTMGHTFGDELL 619 +A++D L+GLPNR + L + ++ G A+ +LD+D FK INDT+GH GD LL Sbjct: 433 MAHHDALTGLPNRTLFFDRLRQGLYKKERSGKMLAVIYLDLDRFKIINDTLGHHTGDMLL 492 Query: 620 VKAGERLLELSDGRCRHFRFGGDEFVILIKEVDRYAEVIYYAESLVQGFSAPFELDASSV 679 + +RL + R GGDEF I+I E+ A+ + AE ++ FSAPF L+ + Sbjct: 493 KEVADRLRGVVRKADTISRLGGDEFTIIIDEIATPADSLLVAEKILHVFSAPFRLEKHEM 552 Query: 680 HISISIGIASYPENGTDAGELLKNADIAMYKAKEAGKGTYVVYGEEMQQHFDERMIVEHH 739 I+ S+G+ YP +G A +LLKNAD AMY AKE G+ TY + EEM ER+ +E Sbjct: 553 FITASMGVTLYPNDGDTAEKLLKNADTAMYHAKEEGRNTYQFFSEEMNSRVSERLSMETG 612 Query: 740 LRNAIANNELSLQYQPLVDTGTGRIWGFEALIRWNNPVLGIVSPLSFITIAEDCRLIVPI 799 LR+A+A NE L YQP V+T TGRI G EALIRW P G++ P +FI +AE+ LI+PI Sbjct: 613 LRHALARNEFLLHYQPRVNTTTGRIVGVEALIRWQQPQKGLILPDAFIPLAEETGLIIPI 672 Query: 800 GEWVLRKACRFMKELQAQGYEGYHISVNISVVQLMLDDFTDMVLAVLEDTGLAPEYLELE 859 GEWVLR C + Q G+ ISVNIS Q D+ D + +L +TGL P LELE Sbjct: 673 GEWVLRNTCTQARAWQEAGFAQMRISVNISCRQFTHDNLPDTIRGILRETGLQPSCLELE 732 Query: 860 ITESIFMESFEAVSSKLEPLKQRGIGIALDDFGTGYSSLSYLKQLPITTLKIDKSFIDSI 919 ITES+ M + E S L LK+ GI IA+DDFGTGYSSLS LK+LP LKIDKSF+ I Sbjct: 733 ITESVIMLNPERAISLLNELKEMGISIAIDDFGTGYSSLSLLKRLPADILKIDKSFVSGI 792 Query: 920 DTPNNMS---LASSIVTIGHDMGLNVTAEGVETQEQLAFLEQTSCDKIQGYFISRPIP 974 P N S L ++I+ +GH+MGL + AEGVE QEQL FLE+ +C ++QGY+ S+P+P Sbjct: 793 --PGNKSDETLVATIINLGHNMGLGLVAEGVERQEQLHFLEERNCQEVQGYYFSKPLP 848 >B0CAI7.1 B0CAI7_ACAM1 Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF domains Length = 862 Score = 387 bits (993), Expect = e-105, Method: Compositional matrix adjust. Identities = 216/597 (36%), Positives = 321/597 (53%), Gaps = 49/597 (8%) Query: 382 KRMRSHLEKSNERFSLAAFGSDAVIWDVDMSTMIYYFSDSWYELLGYERGEVNESHGGWR 441 KR L +S ER++ AA G++ +WD + + YFS W ++GYE E+++ W Sbjct: 294 KRAEQILRESEERYAAAARGANDGLWDWHLRSNRVYFSPRWKAMIGYEEDEISDRCEEWL 353 Query: 442 EIVHPEDAEQEDRLRTQHLEGRSSYYYAEYRMRSKSGEYIWFQARGKVLRSAGGGYIRFA 501 + +HP D ++ + + HL+G ++++ +E+R+R K+GEY WF++RG LR R A Sbjct: 354 DRLHPSDRDRLKQELSMHLKGETNHFQSEFRLRHKNGEYRWFRSRGMALRDTDQQPYRIA 413 Query: 502 GSMVDVTDRKGYESKLQISYQELESTYEELTALQDELMEQYNKVVENQELLQASEEKYRL 561 GS D+T E +++L+ Sbjct: 414 GSQTDIT---------------------EYHLAREQLVHD-------------------- 432 Query: 562 LAYNDVLSGLPNRLSLSEELTDFI---EKHPGGQAALFFLDIDNFKYINDTMGHTFGDEL 618 A +D L+ LPNR+ + LT I ++HP Q A FLD+D FK IND++GH GD L Sbjct: 433 -ALHDALTCLPNRVLFMDRLTQAIKQYQRHPEDQFATLFLDLDRFKIINDSLGHMIGDRL 491 Query: 619 LVKAGERLLELSDGRCRHFRFGGDEFVILIKEVDRYAEVIYYAESLVQGFSAPFELDASS 678 L++ G RL + R GGDEFVIL+ + V+ AE + Q F ++ Sbjct: 492 LIEVGNRLQFCLRDQDTVARIGGDEFVILLNTIQNMEHVLQTAERIQQQLKQAFSIEGHE 551 Query: 679 VHISISIGIASYPENGTDAGELLKNADIAMYKAKEAGKGTYVVYGEEMQQHFDERMIVEH 738 + SIGIA A ELL++AD AMY+AK GK Y ++ M+ +E+ Sbjct: 552 IFTGTSIGIALSSPEYQHAEELLRDADTAMYRAKNLGKNRYEIFSSSMRSQVLALSQLEN 611 Query: 739 HLRNAIANNELSLQYQPLVDTGTGRIWGFEALIRWNNPVLGIVSPLSFITIAEDCRLIVP 798 LR AI E L YQP+V T + G EAL+RW++P G++ P F+ +AE+ LI+P Sbjct: 612 DLRRAIDRQEFQLFYQPIVSLDTQNLVGLEALVRWHHPERGLILPSEFVPMAEEAGLIIP 671 Query: 799 IGEWVLRKACRFMKELQAQGYE---GYHISVNISVVQLMLDDFTDMVLAVLEDTGLAPEY 855 +G WVL +ACR M +L Q Y ++VNIS Q +F + + AVLEDT L Sbjct: 672 LGGWVLAQACRQM-QLWQQHYSLATDLQLNVNISSRQFSQPNFVNDIHAVLEDTNLPCHR 730 Query: 856 LELEITESIFMESFEAVSSKLEPLKQRGIGIALDDFGTGYSSLSYLKQLPITTLKIDKSF 915 L+LEITE + M+ V+ KL+ +K GI + +DDFGTGYSSL+YL P+ TLKID+SF Sbjct: 731 LKLEITEGVLMDHASDVADKLDAIKTLGIKLGIDDFGTGYSSLNYLNAFPVDTLKIDRSF 790 Query: 916 IDSIDTPNNMSLASSIVTIGHDMGLNVTAEGVETQEQLAFLEQTSCDKIQGYFISRP 972 + + + + +IV + H++ ++V AEGVE +EQ L Q +C+ QGY S P Sbjct: 791 VGRMSSEEGFEIVRTIVNLAHNLHMDVVAEGVELEEQAEELTQMNCEYAQGYLFSEP 847 >B9LZ98.1 B9LZ98_GEOSF Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) Length = 912 Score = 379 bits (973), Expect = e-102, Method: Compositional matrix adjust. Identities = 192/435 (44%), Positives = 272/435 (62%), Gaps = 3/435 (0%) Query: 553 QASEEKYRLLAYNDVLSGLPNRLSLSEELTDFIEK--HPGGQAALFFLDIDNFKYINDTM 610 + +E++ + LAY D L+GLPNR L + L I + + A+ FLD+D FK INDT+ Sbjct: 472 KKAEDEIQQLAYYDTLTGLPNRSLLQDRLGQGIVQAVRDNRKVAIMFLDLDRFKSINDTL 531 Query: 611 GHTFGDELLVKAGERLLELSDGRCRHFRFGGDEFVILIKEVDRYAEVIYYAESLVQGFSA 670 GH GD LL ERL E R GGDEFVI+I ++ ++ AE ++ S Sbjct: 532 GHVAGDSLLATVAERLTECVRETDTVARIGGDEFVIIISAIEHAEDLNKIAEKILAAISK 591 Query: 671 PFELDASSVHISISIGIASYPENGTDAGELLKNADIAMYKAKEAGKGTYVVYGEEMQQHF 730 P L+ + I+ SIGIA YPE+GTD LLKNAD+AMYKAK+ GK + + EM Sbjct: 592 PLVLNDQEIFITASIGIAIYPEDGTDVQGLLKNADLAMYKAKDQGKNAFQYFSREMNVQA 651 Query: 731 DERMIVEHHLRNAIANNELSLQYQPLVDTGTGRIWGFEALIRWNNPVLGIVSPLSFITIA 790 E +I+E+ LR A+ NE + YQP +D +GR+ G EALIRW +P LG++ P FI +A Sbjct: 652 LEHLILENSLRRALERNEFVIFYQPQMDLKSGRLVGMEALIRWQHPDLGLLPPSRFIPMA 711 Query: 791 EDCRLIVPIGEWVLRKACRFMKELQAQGYEGYHISVNISVVQLMLDDFTDMVLAVLEDTG 850 E+ LI+PIGEW L+ AC + G+ ++VN+ +Q F +++ AVL+ TG Sbjct: 712 EETGLILPIGEWALQTACAKNRAWMDAGFMPLRVAVNLCGIQFRQKKFIELIEAVLKKTG 771 Query: 851 LAPEYLELEITESIFMESFEAVSSKLEPLKQRGIGIALDDFGTGYSSLSYLKQLPITTLK 910 LAP LELE+TES+ M E ++ L LK+ G+ +A+DDFGTGYSSLSYLK PI +K Sbjct: 772 LAPSQLELELTESMLMSKAEESTTVLHKLKEMGVSLAIDDFGTGYSSLSYLKNFPINRVK 831 Query: 911 IDKSFI-DSIDTPNNMSLASSIVTIGHDMGLNVTAEGVETQEQLAFLEQTSCDKIQGYFI 969 ID+SFI D + P++ ++ S+I+ + H++ L VTAEGVE QL FL +C++IQGY + Sbjct: 832 IDRSFIRDVPNNPDDTAIVSAIIAMAHNLNLKVTAEGVENHSQLEFLSTRNCNEIQGYLL 891 Query: 970 SRPIPQKEVAGWISG 984 S P+P+ E ++ G Sbjct: 892 SSPLPEAEFTRFLRG 906 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.136 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 5,794,551,125 Number of extensions: 248786785 Number of successful extensions: 731199 Number of sequences better than 1.0e-05: 18278 Number of HSP's gapped: 695229 Number of HSP's successfully gapped: 18878 Length of query: 988 Length of database: 3,060,696,203 Length adjustment: 146 Effective length of query: 842 Effective length of database: 1,685,228,013 Effective search space: 1418961986946 Effective search space used: 1418961986946 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 136 (57.0 bits)