BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0137.0002.p (412 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KK28.1 B3KK28_9BACI Aspartokinase EC=2.7.2.4 657 0.0 C0Z9I8.1 C0Z9I8_BREBN Aspartokinase 2 EC=2.7.2.4 456 e-126 Q3AAV6.1 Q3AAV6_CARHZ Aspartokinase EC=2.7.2.4 441 e-122 A4J3P8.1 A4J3P8_DESRM Aspartokinase EC=2.7.2.4 439 e-121 A6CSE9.1 A6CSE9_9BACI Aspartokinase EC=2.7.2.4 437 e-121 >B3KK28.1 B3KK28_9BACI Aspartokinase EC=2.7.2.4 Length = 417 Score = 657 bits (1696), Expect = 0.0, Method: Compositional matrix adjust. Identities = 324/412 (78%), Positives = 360/412 (87%) Query: 1 MKFGGSSVGDIERMKRVAGRIADKQDEGHRCVVVVSAMGDTTDELIDQAKQLNGQPPARE 60 MKFGGSSVGD ERMKRVA RI +KQDEGH+CVVVVSAMGDTTD+LIDQAK LN PPARE Sbjct: 6 MKFGGSSVGDTERMKRVARRIVEKQDEGHQCVVVVSAMGDTTDDLIDQAKLLNENPPARE 65 Query: 61 MDMLMTTGEQISVALLSIALSGIGRSAVSYTGWQAGFRTDETHGRARINEIDPRRVLESL 120 MDMLMTTGEQIS++LLS+A+ G+GR AVS TGWQAGFRT+ HG+ARI +I P RV ++L Sbjct: 66 MDMLMTTGEQISISLLSMAIHGLGRKAVSLTGWQAGFRTEAVHGKARITDIKPERVHKAL 125 Query: 121 ERGQIVIVAGFQGMTVDGEITTLGRGGSDTTXXXXXXXXXXDVCEIYTDVDGIYSTDPRI 180 G +VIVAGFQGM+ DGEITTLGRGGSDTT DVCEIYTDVDGIYSTDPR+ Sbjct: 126 GEGNVVIVAGFQGMSEDGEITTLGRGGSDTTAVALAAAIQADVCEIYTDVDGIYSTDPRV 185 Query: 181 VKTARKLNEISYDEMLELANLGAAVLHPRAVEYAKRYQVKLVVRSSFNHNEGTVVKEEAS 240 VK ARKL EISYDEMLELANLGAAVLHPRAVEYAK QVKLVVRSSFNHNEGTVVKEE S Sbjct: 186 VKCARKLKEISYDEMLELANLGAAVLHPRAVEYAKHNQVKLVVRSSFNHNEGTVVKEETS 245 Query: 241 MEQGVVVSGIAYDKNVARISILGVPDVPGVLAQVFGKLAEEGVDVDIIVQSGVQNEKADF 300 MEQGVVVSGIA+DKNVARISILGV D PGVLAQVFG+LA+E +DVDIIVQSGVQN +ADF Sbjct: 246 MEQGVVVSGIAFDKNVARISILGVADTPGVLAQVFGELAKESIDVDIIVQSGVQNGEADF 305 Query: 301 SFTVALSELAHAKKVIEGLHSELPYREVTSEDNLVKVSIVGAGMVSHPGVAAQMFDVISK 360 SFTV+L++ A VIE + +LPYR+VTSED+LVKVSIVGAGMVSHPGVAAQMFDVIS+ Sbjct: 306 SFTVSLADRERALSVIEHIRGKLPYRDVTSEDHLVKVSIVGAGMVSHPGVAAQMFDVISR 365 Query: 361 EGVSIKMVSTSEIKVSCVIESGNLQKIIQALHTAYNLDTEEQAFVGGPKDRR 412 +GVSIKMVSTSEIKVSCVIE NL+ ++QALHTAY LDT++QA VGGP+ RR Sbjct: 366 QGVSIKMVSTSEIKVSCVIEGSNLEGVVQALHTAYGLDTDQQASVGGPQVRR 417 >C0Z9I8.1 C0Z9I8_BREBN Aspartokinase 2 EC=2.7.2.4 Length = 413 Score = 456 bits (1174), Expect = e-126, Method: Compositional matrix adjust. Identities = 227/406 (55%), Positives = 303/406 (74%) Query: 2 KFGGSSVGDIERMKRVAGRIADKQDEGHRCVVVVSAMGDTTDELIDQAKQLNGQPPAREM 61 K+GG+SVG IER+ RVA RI ++EGH VVVVSAMG +TD L+D AKQ++ P REM Sbjct: 7 KYGGTSVGTIERILRVADRIISYKEEGHDVVVVVSAMGKSTDVLVDMAKQISAYPSEREM 66 Query: 62 DMLMTTGEQISVALLSIALSGIGRSAVSYTGWQAGFRTDETHGRARINEIDPRRVLESLE 121 DML+TTGEQ+S+ALLS+AL G A+S TGWQAG T+ HGRARI +IDP R+ L Sbjct: 67 DMLLTTGEQVSIALLSMALHTKGYDAISLTGWQAGITTEAIHGRARIKQIDPERIQSELG 126 Query: 122 RGQIVIVAGFQGMTVDGEITTLGRGGSDTTXXXXXXXXXXDVCEIYTDVDGIYSTDPRIV 181 RG++VIVAGFQG++ +GEITTLGRGGSDT+ + CEI+TDV G+Y+ DPR+V Sbjct: 127 RGRVVIVAGFQGISDEGEITTLGRGGSDTSAVTLAASLNAEKCEIFTDVSGVYTADPRMV 186 Query: 182 KTARKLNEISYDEMLELANLGAAVLHPRAVEYAKRYQVKLVVRSSFNHNEGTVVKEEASM 241 A KL+ ISYDEMLELANLGA VLHPR+VE AK+Y+V+LVVRSSF +GT V+E A+M Sbjct: 187 PAASKLDTISYDEMLELANLGAGVLHPRSVEAAKKYKVRLVVRSSFTAEDGTYVEEVANM 246 Query: 242 EQGVVVSGIAYDKNVARISILGVPDVPGVLAQVFGKLAEEGVDVDIIVQSGVQNEKADFS 301 E G VVSG+A+D++VA+I+++G+P G L+++F LA+ V+VDII+QS + S Sbjct: 247 ETGRVVSGVAHDEDVAKITVVGMPAKVGTLSRLFNTLADNQVNVDIIIQSSYDATVTNIS 306 Query: 302 FTVALSELAHAKKVIEGLHSELPYREVTSEDNLVKVSIVGAGMVSHPGVAAQMFDVISKE 361 FTVA +L A ++ EL + +V E++L KVSIVG+GM+++PGVAA+MF V++++ Sbjct: 307 FTVAADDLKKALDTLDRNKEELGFEKVDFEESLTKVSIVGSGMINNPGVAAEMFRVLAEK 366 Query: 362 GVSIKMVSTSEIKVSCVIESGNLQKIIQALHTAYNLDTEEQAFVGG 407 +SIKMVSTS+IKVSCVI + + +++LH+AY LD EE A V G Sbjct: 367 EISIKMVSTSDIKVSCVIPAALTELAVRSLHSAYGLDVEETAVVHG 412 >Q3AAV6.1 Q3AAV6_CARHZ Aspartokinase EC=2.7.2.4 Length = 406 Score = 441 bits (1133), Expect = e-122, Method: Compositional matrix adjust. Identities = 213/397 (53%), Positives = 297/397 (74%), Gaps = 1/397 (0%) Query: 2 KFGGSSVGDIERMKRVAGRIADKQDEGHRCVVVVSAMGDTTDELIDQAKQLNGQPPAREM 61 K+GGSSV + ER+K VA R+A+ GHR VVVSAMGDTTDEL+D +++ PPARE+ Sbjct: 6 KYGGSSVANPERIKNVARRVAEYYRAGHRVAVVVSAMGDTTDELLDLMGEISPNPPAREI 65 Query: 62 DMLMTTGEQISVALLSIALSGIGRSAVSYTGWQAGFRTDETHGRARINEIDPRRVLESLE 121 DML++TGEQ+SVALL++AL +G A S+TG QAG TDE H +ARI EI P RV+ L Sbjct: 66 DMLLSTGEQVSVALLAMALHELGVPARSFTGLQAGIYTDEVHTKARITEIKPERVIACLN 125 Query: 122 RGQIVIVAGFQGMTVDGEITTLGRGGSDTTXXXXXXXXXXDVCEIYTDVDGIYSTDPRIV 181 G++ +VAGFQG+ +G+ITTLGRGGSDTT D+CEIYTDVDG+Y+ DPRIV Sbjct: 126 SGKVAVVAGFQGVNREGDITTLGRGGSDTTAVALAAALKADICEIYTDVDGVYTADPRIV 185 Query: 182 KTARKLNEISYDEMLELANLGAAVLHPRAVEYAKRYQVKLVVRSSFNHNEGTVVKEEASM 241 ARK+ EISY+EMLELA+LGA VL PR+V++A+ Y+V++ VRSSFN+NEGTV+KEE + Sbjct: 186 PDARKIKEISYEEMLELASLGAVVLQPRSVDFARNYKVEVHVRSSFNYNEGTVLKEERDL 245 Query: 242 EQGVVVSGIAYDKNVARISILGVPDVPGVLAQVFGKLAEEGVDVDIIVQSGVQNE-KADF 300 E+ VV+G+A+DKNV +I + GVPD PGV ++F +LA ++VD+I+QS + E + D Sbjct: 246 EKKGVVTGVAHDKNVVKIGVFGVPDQPGVAYRLFSELAAHNINVDMIIQSAGKEEGQNDI 305 Query: 301 SFTVALSELAHAKKVIEGLHSELPYREVTSEDNLVKVSIVGAGMVSHPGVAAQMFDVISK 360 SFT+ ++LA +++E + +L R T ++ + KVSIVGAGMV++PGVAA+MF+ + + Sbjct: 306 SFTIGKNDLAKTVEILEDVVKKLSARGYTYDEKVAKVSIVGAGMVTYPGVAAKMFEALYE 365 Query: 361 EGVSIKMVSTSEIKVSCVIESGNLQKIIQALHTAYNL 397 E ++I+M+STSEIKVSC+I +++ + A+H + L Sbjct: 366 ENINIQMISTSEIKVSCIIAEDAVERAVNAIHKKFEL 402 >A4J3P8.1 A4J3P8_DESRM Aspartokinase EC=2.7.2.4 Length = 412 Score = 439 bits (1130), Expect = e-121, Method: Compositional matrix adjust. Identities = 209/404 (51%), Positives = 294/404 (72%) Query: 2 KFGGSSVGDIERMKRVAGRIADKQDEGHRCVVVVSAMGDTTDELIDQAKQLNGQPPAREM 61 KFGGSSV D ER+KRVA R+ ++ +G++ VV VSAMGDTTD+L+ AKQ+ P REM Sbjct: 6 KFGGSSVADPERIKRVARRVVEEHQKGNQVVVTVSAMGDTTDDLVSLAKQVTNDPSEREM 65 Query: 62 DMLMTTGEQISVALLSIALSGIGRSAVSYTGWQAGFRTDETHGRARINEIDPRRVLESLE 121 DML++TGEQIS+ALLS+A+ +G +S TG Q G TD+ H +A+I +I+ RV E LE Sbjct: 66 DMLLSTGEQISIALLSMAIRDLGSDVISLTGGQVGIYTDDVHSKAKILKIETSRVKEELE 125 Query: 122 RGQIVIVAGFQGMTVDGEITTLGRGGSDTTXXXXXXXXXXDVCEIYTDVDGIYSTDPRIV 181 +G++V+VAGFQG+ + +ITTLGRGGSDTT D+CEI+TDVDG+Y+TDPR+V Sbjct: 126 QGRVVVVAGFQGIKSNHDITTLGRGGSDTTAVALAAALKADICEIFTDVDGVYTTDPRLV 185 Query: 182 KTARKLNEISYDEMLELANLGAAVLHPRAVEYAKRYQVKLVVRSSFNHNEGTVVKEEASM 241 A KL IS+DEMLELA+LGA VLHPR+VE AK+Y + + VR+SF+H EGT+V+E +M Sbjct: 186 PEASKLKNISFDEMLELASLGAQVLHPRSVELAKQYGIPIHVRTSFDHREGTIVEEAPNM 245 Query: 242 EQGVVVSGIAYDKNVARISILGVPDVPGVLAQVFGKLAEEGVDVDIIVQSGVQNEKADFS 301 E VVSG+A+D NVA+I + VPD PGV ++F L++ ++VD+I+QS ++N D Sbjct: 246 ENAPVVSGVAHDYNVAKIGLFDVPDQPGVAKKIFKALSKHNLNVDMIIQSAMRNNMNDIG 305 Query: 302 FTVALSELAHAKKVIEGLHSELPYREVTSEDNLVKVSIVGAGMVSHPGVAAQMFDVISKE 361 FT +L A + IE + E+ +R ++++ KVSIVGAGM+SHPGVAA MF+ ++ E Sbjct: 306 FTTTQDDLRKALQTIEAIQQEVGFRGYNHDEDVAKVSIVGAGMISHPGVAADMFEALADE 365 Query: 362 GVSIKMVSTSEIKVSCVIESGNLQKIIQALHTAYNLDTEEQAFV 405 G++++M++TSEIKVSCVI+ +K ++ALH + LD +A + Sbjct: 366 GINLEMITTSEIKVSCVIKRSETEKAVKALHKKFKLDNLAEASI 409 >A6CSE9.1 A6CSE9_9BACI Aspartokinase EC=2.7.2.4 Length = 414 Score = 437 bits (1125), Expect = e-121, Method: Compositional matrix adjust. Identities = 211/401 (52%), Positives = 293/401 (73%) Query: 2 KFGGSSVGDIERMKRVAGRIADKQDEGHRCVVVVSAMGDTTDELIDQAKQLNGQPPAREM 61 KFGG+SVGDIER+K VAGR+ D++ +G+ VVVVSAMG TTD L+D A Q + +P REM Sbjct: 7 KFGGTSVGDIERIKNVAGRVIDEKKQGNDVVVVVSAMGKTTDGLVDLAYQASAKPSKREM 66 Query: 62 DMLMTTGEQISVALLSIALSGIGRSAVSYTGWQAGFRTDETHGRARINEIDPRRVLESLE 121 DM++TTGEQI+++LL++AL +G AVS TGWQAG T+ HG ARI I+ R+ +L Sbjct: 67 DMILTTGEQITISLLTMALQEMGYDAVSMTGWQAGIETEGIHGNARITNINTERINHNLS 126 Query: 122 RGQIVIVAGFQGMTVDGEITTLGRGGSDTTXXXXXXXXXXDVCEIYTDVDGIYSTDPRIV 181 +IV+ AGFQG+ +GEITTLGRGGSDTT + C+IYTDVDG+Y++DPR V Sbjct: 127 ENRIVVAAGFQGLADNGEITTLGRGGSDTTAVALAAALKAERCDIYTDVDGVYTSDPRYV 186 Query: 182 KTARKLNEISYDEMLELANLGAAVLHPRAVEYAKRYQVKLVVRSSFNHNEGTVVKEEASM 241 K+ARKL ++YDEMLELANLGA VLHPRAVE+AK Y V LVVRSS EGT+++EE SM Sbjct: 187 KSARKLASVAYDEMLELANLGAGVLHPRAVEFAKNYGVPLVVRSSMEKLEGTIIEEEVSM 246 Query: 242 EQGVVVSGIAYDKNVARISILGVPDVPGVLAQVFGKLAEEGVDVDIIVQSGVQNEKADFS 301 E G++V G+A+++ + R+++LG+ + L+ +F LA+ ++VDII+QS + + + S Sbjct: 247 ETGLIVRGVAFEEEIIRMTVLGLQNEITSLSSIFTTLAQNHINVDIIIQSKTETDSINLS 306 Query: 302 FTVALSELAHAKKVIEGLHSELPYREVTSEDNLVKVSIVGAGMVSHPGVAAQMFDVISKE 361 F++ ++L A +V++ EL + + E L KVSIVG+GM+S+PGVAAQMF+V++K Sbjct: 307 FSIKRNDLEEAIEVLQSNREELGFSSIEHESGLAKVSIVGSGMISNPGVAAQMFEVLAKN 366 Query: 362 GVSIKMVSTSEIKVSCVIESGNLQKIIQALHTAYNLDTEEQ 402 + IKMVSTSEIKVS V++ ++ K + LHT +NLD E+ Sbjct: 367 EIPIKMVSTSEIKVSAVVDETHMLKAAEVLHTEFNLDKTEK 407 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.315 0.133 0.365 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,199,669,417 Number of extensions: 83410775 Number of successful extensions: 267670 Number of sequences better than 1.0e-05: 2606 Number of HSP's gapped: 262412 Number of HSP's successfully gapped: 2667 Length of query: 412 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 274 Effective length of database: 1,760,596,133 Effective search space: 482403340442 Effective search space used: 482403340442 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 132 (55.5 bits)