BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0128.0035.p (298 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B5XSB7.1 B5XSB7_KLEP3 Dihydrodipicolinate synthetase family protein 180 1e-43 Q4WBH1.1 Q4WBH1_ASPFU Dihydrodipicolinate synthetase family prot... 151 7e-35 Q8EQJ1.1 DAPA_OCEIH Dihydrodipicolinate synthase EC=4.2.1.52 149 3e-34 Q5ARR8.1 Q5ARR8_EMENI Putative uncharacterized protein 147 1e-33 A8VW77.1 A8VW77_9BACI Dihydrodipicolinate synthase EC=4.2.1.52 147 1e-33 >B5XSB7.1 B5XSB7_KLEP3 Dihydrodipicolinate synthetase family protein Length = 307 Score = 180 bits (457), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 97/289 (33%), Positives = 165/289 (57%), Gaps = 3/289 (1%) Query: 5 DLKNKLKGIYVLAITPMMDTQAFDPSALRRNIDHYIASGAHGIIVGGTYAEYPSLTSDER 64 + + +L+GI+ + +TP + A D ALR NI+ I G G+++GGTY E+P +T +ER Sbjct: 6 ECRERLRGIFNITVTPFTVSGAIDFPALRENIERVIGLGYDGLLIGGTYGEFPVMTVEER 65 Query: 65 KQLFTXXXXXXXGRVPLLCCTAASGTDEASELA-HAAKLAGADGVMVTPPYVSEVRPQDI 123 ++LF RV ++ C+A++ +A EL A++L G MVT P+VSE+ Q I Sbjct: 66 RELFHQVMACVDDRVAVMLCSASADPRDARELTLLASELGGLP--MVTAPFVSEITDQQI 123 Query: 124 LYHFQLLNESAELPILIYNSASIGVHLSPEEIAGLAKLDNVAGVKQGATDLHSLVRTVAY 183 + +F+ + ++ IL+YN+ IG+ LSP + LA++ NV G+KQG + ++ + Sbjct: 124 VSYFKEMAPLSKTGILVYNAPGIGITLSPALLEQLAEIPNVVGIKQGDLNPTAIDQIANR 183 Query: 184 AGNDISVMCGSDGLILGGLASGLPGCTSTNANFMTSEFVALYNEFQQGENARALERYYRW 243 + + C SD LG + +G G ++TN+ + + + +QG+ A A + + W Sbjct: 184 LRGRLRLFCASDLAFLGPMMAGFDGISTTNSGALPELIINTFRAVEQGDAATARDLHQLW 243 Query: 244 QPIRDLARKYGQPAMVKAALDIIGLPSGPVRAPFRTLGEDARADIARTL 292 R LARK+GQP +VKAA+ + G G VRAP + + + A A++ + Sbjct: 244 YAYRALARKHGQPQLVKAAMALRGFNGGTVRAPLKPIDDAALAELTHVM 292 >Q4WBH1.1 Q4WBH1_ASPFU Dihydrodipicolinate synthetase family protein EC=4.2.1.- Length = 296 Score = 151 bits (382), Expect = 7e-35, Method: Compositional matrix adjust. Identities = 100/292 (34%), Positives = 154/292 (52%), Gaps = 6/292 (2%) Query: 10 LKGIYVLAITPMMDTQA-FDPSALRRNIDHYIASGAHGIIVGGTYAEYPSLTSDERKQLF 68 L GI V ITP D Q D + L+ +ID IA+G HG++ GG+ E+ ++T+ ERK+L Sbjct: 4 LHGILVALITPFTDDQKHIDAACLKAHIDRLIAAGIHGLVPGGSTGEFTTMTTAERKELT 63 Query: 69 TXXXXXXXGRVPLLCCTAASGTDEASELAHAAKLAGADGVMVTPPYVSEVRPQDILYHFQ 128 GRVP++ T ++ T EA ELA A GA +MV PP+ V + + Sbjct: 64 ELCIKFAAGRVPVVVGTGSTSTAEALELATHAASVGAAALMVVPPFYDPVSLEQLTELMA 123 Query: 129 LLNESAELPILIYN--SASIGVHLSPEEIAGLAKLDNVAGVKQGATDLHSLVRTVAYAGN 186 ++ ++ LPI+ YN SAS G+ L+P EIAGL+K+ V +K + D + V + Sbjct: 124 EIHTASGLPIMYYNIPSAS-GLKLTPGEIAGLSKV-GVKYLKDTSGDAPAFTELVFGLSD 181 Query: 187 DISVMCGSDGLILGGLASGLPGCTSTNANFMTSEFVALYNEFQQGEN-ARALERYYRWQP 245 I+ G D L GLA+G PG ANF+ V LY ++ R E + + P Sbjct: 182 KITAFNGYDTLTFYGLAAGCPGGVWGAANFIPELAVELYETVSVKKDLKRGRELWTKIWP 241 Query: 246 IRDLARKYGQPAMVKAALDIIGLPSGPVRAPFRTLGEDARADIARTLQQTGI 297 I + A VKA +++ G +G +R PF++LG + +A++ + L G+ Sbjct: 242 ICKFLESHNYAAAVKAGVELTGQETGGLRKPFKSLGPELQAELKQLLIDAGV 293 >Q8EQJ1.1 DAPA_OCEIH Dihydrodipicolinate synthase EC=4.2.1.52 Length = 295 Score = 149 bits (376), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 86/278 (30%), Positives = 141/278 (50%), Gaps = 5/278 (1%) Query: 18 ITPMMDTQAFDPSALRRNIDHYIASGAHGIIVGGTYAEYPSLTSDERKQLFTXXXXXXXG 77 +TP + D AL IDH I +G+ G++V GT E P+LT +ER +LF G Sbjct: 11 VTPFDKHEEIDFQALDHLIDHLINNGSDGLVVAGTTGESPTLTHEERIKLFEYVVKKVNG 70 Query: 78 RVPLLCCTAASGTDEASELAHAAKLAGADGVMVTPPYVSEVRP-QDILY-HFQLLNESAE 135 VP++ T ++ T + EL G DGVM+ PY + +P QD +Y HF+++ ES E Sbjct: 71 AVPVIAGTGSNYTKASIELTKEVAKTGVDGVMLVAPYYN--KPSQDSMYEHFKVIAESTE 128 Query: 136 LPILIYN-SASIGVHLSPEEIAGLAKLDNVAGVKQGATDLHSLVRTVAYAGNDISVMCGS 194 LP+++YN GV + + L+++DN+ +K + +L + + ++ SV G Sbjct: 129 LPVMLYNVPGRTGVDMDVSTVVRLSQIDNIVSIKDASGNLEKMTNIIRLTDDNFSVYSGE 188 Query: 195 DGLILGGLASGLPGCTSTNANFMTSEFVALYNEFQQGENARALERYYRWQPIRDLARKYG 254 D L L LA G G S +++ + ++ + F+QG+ A A + R P+ Sbjct: 189 DSLTLPALAIGADGIVSVSSHIIGNDMQEMIQRFEQGQVAEAANIHQRVLPVMQEMFANP 248 Query: 255 QPAMVKAALDIIGLPSGPVRAPFRTLGEDARADIARTL 292 P VK AL++ +P G VR P L ++ ++ L Sbjct: 249 SPVPVKTALNLQSVPVGKVRLPLIELTDEQLQNLQSVL 286 >Q5ARR8.1 Q5ARR8_EMENI Putative uncharacterized protein Length = 298 Score = 147 bits (371), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 99/292 (33%), Positives = 149/292 (51%), Gaps = 6/292 (2%) Query: 10 LKGIYVLAITPMMDTQ-AFDPSALRRNIDHYIASGAHGIIVGGTYAEYPSLTSDERKQLF 68 L GI V +TP D + A D + L +I H + +G HG++ GG+ E+ +L+ ERKQL Sbjct: 6 LNGILVALVTPFTDDKTAIDEARLELHIKHMLDAGIHGLVPGGSTGEFTTLSLSERKQLT 65 Query: 69 TXXXXXXXGRVPLLCCTAASGTDEASELAHAAKLAGADGVMVTPPYVSEVRPQDILYHFQ 128 GRVP++ T A+ T EA ELA AK GA VMV PP+ V Q + Sbjct: 66 ELCVRFAGGRVPVVAGTGATSTSEAVELAVHAKEVGAAAVMVVPPFYDPVNLQQLTELLA 125 Query: 129 LLNESAELPILIYN--SASIGVHLSPEEIAGLAKLDNVAGVKQGATDLHSLVRTVAYAGN 186 ++E + LPI+ YN SAS G+ LSP EIAGL+++ V +K + D + V + Sbjct: 126 EIHEKSTLPIMYYNIPSAS-GLKLSPSEIAGLSRV-GVRWLKDTSGDAPAFTELVFGLSD 183 Query: 187 DISVMCGSDGLILGGLASGLPGCTSTNANFMTSEFVALYNEFQQGENA-RALERYYRWQP 245 I+ + G D L GLA+G PG AN + V LY ++ + E + + P Sbjct: 184 QITALNGWDTLTFYGLAAGCPGGVWGAANIIPELAVELYEAVSIKKDLDKGKELWSKAWP 243 Query: 246 IRDLARKYGQPAMVKAALDIIGLPSGPVRAPFRTLGEDARADIARTLQQTGI 297 I + A VK +++ G +G +R PF LG + + ++ L+ G+ Sbjct: 244 ICKFLESHNYAAAVKTGVELTGQATGGLRKPFALLGPELQEELKGLLKNAGV 295 >A8VW77.1 A8VW77_9BACI Dihydrodipicolinate synthase EC=4.2.1.52 Length = 295 Score = 147 bits (371), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 87/276 (31%), Positives = 143/276 (51%), Gaps = 1/276 (0%) Query: 18 ITPMMDTQAFDPSALRRNIDHYIASGAHGIIVGGTYAEYPSLTSDERKQLFTXXXXXXXG 77 +TP D D + I+H I +G+ I++ GT E P+L+ DE+ LF G Sbjct: 11 VTPFNDDMEVDFERTEQLIEHLIRTGSDAIVISGTTGEAPTLSIDEKNALFRFCVNTVNG 70 Query: 78 RVPLLCCTAASGTDEASELAHAAKLAGADGVMVTPPYVSEVRPQDILYHFQLLNESAELP 137 R+P++ T + T A EL A++AGADGVM+ PY ++ Q + HF+ + S LP Sbjct: 71 RIPVIAGTGTNSTAMALELTKMAEIAGADGVMLMAPYYNKPNQQGMYEHFKAIATSTTLP 130 Query: 138 ILIYN-SASIGVHLSPEEIAGLAKLDNVAGVKQGATDLHSLVRTVAYAGNDISVMCGSDG 196 +++YN GV+L PE L+++ N+ VK+ + DL ++ + + SV G D Sbjct: 131 VMLYNVPGRTGVNLLPETTIRLSRIPNIVSVKEASGDLDAISEIIEQTSEEFSVYSGDDS 190 Query: 197 LILGGLASGLPGCTSTNANFMTSEFVALYNEFQQGENARALERYYRWQPIRDLARKYGQP 256 L L ++ G G S +++ + E + + FQ+G+ A + PI + P Sbjct: 191 LTLPAMSVGANGVVSVSSHVVGDEMKQMIDFFQEGKFREAAAIHRHLVPIMNGMFIAPSP 250 Query: 257 AMVKAALDIIGLPSGPVRAPFRTLGEDARADIARTL 292 A VKAAL++IG+ +G VR P + ++ + I R L Sbjct: 251 APVKAALEMIGVLTGSVRLPIVPVDDEEKETIHRLL 286 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.135 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,700,975,768 Number of extensions: 68730342 Number of successful extensions: 181593 Number of sequences better than 1.0e-05: 3279 Number of HSP's gapped: 177891 Number of HSP's successfully gapped: 3279 Length of query: 298 Length of database: 3,060,696,203 Length adjustment: 135 Effective length of query: 163 Effective length of database: 1,788,859,178 Effective search space: 291584046014 Effective search space used: 291584046014 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 131 (55.1 bits)